Aips025867.1
Basic Information
- Insect
- Agrotis ipsilon
- Gene Symbol
- ZNF646
- Assembly
- GCA_028554685.1
- Location
- CM052983.1:7214485-7231912[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0013 0.13 13.7 1.0 1 23 229 251 229 251 0.98 2 12 0.012 1.2 10.7 2.3 1 23 258 281 258 281 0.95 3 12 0.15 15 7.2 3.5 1 23 285 307 285 307 0.96 4 12 0.0006 0.06 14.8 4.4 1 23 312 335 312 335 0.98 5 12 0.00013 0.013 16.9 1.9 1 23 339 362 339 362 0.97 6 12 0.28 28 6.4 0.4 5 22 385 402 382 406 0.89 7 12 0.0075 0.76 11.3 0.8 2 23 415 436 414 436 0.96 8 12 0.0026 0.26 12.8 1.6 1 23 454 477 454 477 0.97 9 12 6e-06 0.00061 21.0 1.8 2 23 487 508 486 508 0.97 10 12 1.4e-05 0.0014 19.9 2.4 1 23 514 536 514 536 0.98 11 12 5.1e-05 0.0051 18.1 0.2 1 23 542 564 542 564 0.98 12 12 3.5e-06 0.00035 21.8 2.2 1 23 570 593 570 593 0.98
Sequence Information
- Coding Sequence
- atggaaaaaatatcaaTGTGTAGACTATGTTTAGTGGAAAATGTTAGAATGTTTGTAGTGAGAAATAAGGACTTACAAGAGACATATGAGAAACTGACTAATACtccatttGTAAGTGAAGACAGTAGACCGATGCTCGCTTGTGTCTTCTGCTACACTAGACTGAAGCAATGCTGTCAATTGCAGAGGAAATGTCTGGAAGCAGAGAAGCTGTTCACTCAGATGTTGAATGGTGAATTTGGAGTAAGTTATGATAAAGGAGaagtgGAATGCTTTGGAGGATTCATCAGGACAGTGGTGCAGCATGTCAACATTGACCGGAGTGTGTCAGTAGACAGTGACATCAAGGAGGAACCTGCTGCGGACTGTCACAGAAATGATGATGTTATTAGTTATCAGTTCAAGGTGGAACAGAATGAGGATGTAGATCAGGAGAATACAGATAATGGTTTCCACGAAGATGATATGCCAACAATCCTGGATGGATCAGATTCAGAAGACGATGTGCCGCTAGTGAAGTTCAAGTTTGAACTGGAAGAAGAACCACGaggaaagaagaagaagaaaaagaccAGTAGGAATGAAATACGTAAACCAGACTGCAGCGAGATACTCCTGAGTAAGGAGGAACAGCATGAGAGTCTCCTGGCCAGGTCCAAGTCCTCAAACTACCTTCATTCGCCCTTCAAATGTAACTCTTGCTACAAAGGCTTCGTGGACGCGACGGCCTATGAGAACCACAAGATGAAACATGACTTGAGCAGTGGTCCTCACATGTGCGACATATGTCACATGCGGTACCGCTCCGTGCAACTCTTGCGCACACACGCCAGCACCGCACACGCACGGTTATTCAAATGTAATAAATGCGGCCATGTCTCACATACGAGCAATCAAGCCAGGATTCATGAGAAATGGCATGACGGACATACATACGAATGTCAACTGTGCAGTCATACATTCagGAAGCCTACCTCGTATCTATCTCACATGCGCAAGCGTCACCCGACTGAACACGTGTGTGACGTCTGTGGCGAGAGCTTCGTGGGCAAGCACGGACTGCAGATGCACAAGAGGAAGACTCATGTCAATGGAGAAAAgatGGTGGACCCCGCGGACCCCACGGACCCGGCGTCCAAGAGGTTCTGTATTGAATGTAACATACAGTTCTATAACTCCGAAGCTTGGAAACGACACATACTGCGCTCCCTCAAACATACGCTTAAAACTGAAGAGAGCAAGTCGTGTTCCATATGCCAGTGGACATATGCGGGTCACGAGACACTGGACACTCATATGAAGGAGCATGCTAAAGCCCTGCGCAGGCGCAAGCCGCCCGCCACTGACAAGGAACGGAGTTTTAGATGTAATCAGTGCGGCTCAAAGTTCCTGAGTCGGTCCAAGTTGCAGGCTCACGTCAACAGGACTCACTTGGGACTGAAACATAACAAGAACATCGTGTGCGAGGTTTGCGGGAAGAAATGTTCGTCGAACGCCACCCTGAAGTACCACCAGCGCACCCACACGGGCGAGAAGCCCTACCCGTGCCTCACCTGCTCCAAGCACTTCACAGACAGCAACCAGCTGCGCATCCACGTGCGCACACACACCGGGGAGAGACCCTACGTGTGCGCGGCCTGCGGGAACAGGTTCTCACAGAAGCCCGCGCTCAACAGACATTATAGAGTCCACACCGGGGCAAAGCCCTACACCTGCCAGTACTGCTCTCGAACATTCAGTCAGTCAAATTCACTGAAACTCCACGTGAAAACTGTGCATTTGAAACAGCCAGCCAACaggaagaataaaaataagacCGTTCAAGAAACTAAAGTGGAGAAGAATTGTGAAGAAGAAATTTGTTCATCGCTACAGACTGTTAGGGTGTTGTCTAAATAG
- Protein Sequence
- MEKISMCRLCLVENVRMFVVRNKDLQETYEKLTNTPFVSEDSRPMLACVFCYTRLKQCCQLQRKCLEAEKLFTQMLNGEFGVSYDKGEVECFGGFIRTVVQHVNIDRSVSVDSDIKEEPAADCHRNDDVISYQFKVEQNEDVDQENTDNGFHEDDMPTILDGSDSEDDVPLVKFKFELEEEPRGKKKKKKTSRNEIRKPDCSEILLSKEEQHESLLARSKSSNYLHSPFKCNSCYKGFVDATAYENHKMKHDLSSGPHMCDICHMRYRSVQLLRTHASTAHARLFKCNKCGHVSHTSNQARIHEKWHDGHTYECQLCSHTFRKPTSYLSHMRKRHPTEHVCDVCGESFVGKHGLQMHKRKTHVNGEKMVDPADPTDPASKRFCIECNIQFYNSEAWKRHILRSLKHTLKTEESKSCSICQWTYAGHETLDTHMKEHAKALRRRKPPATDKERSFRCNQCGSKFLSRSKLQAHVNRTHLGLKHNKNIVCEVCGKKCSSNATLKYHQRTHTGEKPYPCLTCSKHFTDSNQLRIHVRTHTGERPYVCAACGNRFSQKPALNRHYRVHTGAKPYTCQYCSRTFSQSNSLKLHVKTVHLKQPANRKNKNKTVQETKVEKNCEEEICSSLQTVRVLSK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00040132; iTF_00042890; iTF_00041166;
- 90% Identity
- -
- 80% Identity
- -