Basic Information

Insect: Agrotis ipsilon
Gene Symbol: CTCF
Assembly: GCA_028554685.1
Location: CM052954.1:22556556-22569126[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0046 0.47 12.0 5.9 1 23 185 207 185 207 0.98

2 11 2.5e-05 0.0026 19.1 1.3 1 23 213 235 213 235 0.98

3 11 6.7e-05 0.0068 17.8 1.7 1 23 241 264 241 264 0.96

4 11 0.032 3.2 9.3 3.2 1 21 270 290 270 292 0.95

5 11 0.0001 0.01 17.2 2.7 1 23 298 320 298 320 0.99

6 11 1.4e-05 0.0014 19.9 5.3 1 23 326 348 326 348 0.98

7 11 0.0015 0.16 13.5 1.5 1 23 356 379 356 379 0.97

8 11 0.017 1.7 10.2 4.3 2 23 386 407 385 407 0.96

9 11 4.4e-05 0.0045 18.3 2.9 1 23 413 435 413 435 0.98

10 11 1.8e-05 0.0018 19.5 1.7 1 23 441 464 441 464 0.93

11 11 1e-05 0.001 20.3 3.2 1 23 478 500 478 500 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0046	0.47	12.0	5.9	1	23	185	207	185	207	0.98
2	11	2.5e-05	0.0026	19.1	1.3	1	23	213	235	213	235	0.98
3	11	6.7e-05	0.0068	17.8	1.7	1	23	241	264	241	264	0.96
4	11	0.032	3.2	9.3	3.2	1	21	270	290	270	292	0.95
5	11	0.0001	0.01	17.2	2.7	1	23	298	320	298	320	0.99
6	11	1.4e-05	0.0014	19.9	5.3	1	23	326	348	326	348	0.98
7	11	0.0015	0.16	13.5	1.5	1	23	356	379	356	379	0.97
8	11	0.017	1.7	10.2	4.3	2	23	386	407	385	407	0.96
9	11	4.4e-05	0.0045	18.3	2.9	1	23	413	435	413	435	0.98
10	11	1.8e-05	0.0018	19.5	1.7	1	23	441	464	441	464	0.93
11	11	1e-05	0.001	20.3	3.2	1	23	478	500	478	500	0.97

Sequence Information

Coding Sequence: ATGCCTCCTCCTGTTAAAAAGGATAAAAACAAGCAATCGCTTATCCAAACATATTTGAACCAAGGAGCAGTCATCACTGTCAATGCCGCCACCGATAGACAGTTAGATACTGGAATGGTGGAGTATTTCGTGGATGAAGATGGCAAGTACTACTATCAGTCTACTGTTGGAGGGCAGGTGGTCCTGAATAGTGCTGAAGCCGCTCAAGAAAATGAGGAGGGTAATGAAGCTTCGGACCCAATTATGACCGGCGACGACGATACTTACCAGACGGTCACCTTTGTCCCCTCTGAGAGCAATGGCGAAGTGAGCTACGTACTAGTAGTGCAGGATGAGAGCAAGGGTGGCGTCGTCAACATTGATCTCAAGGTGGACCAAGCGCGGGAGAACGTAAAGaccGAGGCAGAGGATAAAGGCAACGAGGACGTGTACAACTTCGATGAGGAGGAGGCCggggaggaggaggaggaggatgAAGCAGACACGGAGATGGCGGACGGCACTAAGCCCAAGGTGTCGGCAAAGACACGCACCAAACACGTGCGCCCGAACTTTACGTGCAACTTCTGCTCTTACACTAGTCATCGCCGGTACCTCCTCCTGCGCCACATGAAGTCCCACTCGGAGGACAGGCCGCACAAGTGCAGCGTGTGCGAGCGCGGCTTCAAGACGCTGGCCTCGCTGCAGAACCACGTCAACATGCACAACGGCATCAAGCCGCACGTCTGCAAGTACTGCAACAGCCCCTTTACCACCTCTGGCGAGTTGGTGCGTCACGTACGCTACAAGCACACGCACGAGAAGCCGCACAAGTGCTCGGAGTGCGACTACGCGTCTGTGGAGCTGTCTAAGCTGCGTCGCCACGTTCGTTGCCACACCGGCGAAAGGCCCTATCAGTGCCCGCACTGCACGTACGCATCACCGGACACGTTCAAGCTGAAGCGCCACTTGCGCACCCACACCGGTGAGAAGCCCTACAAATGCGAGCACTGCAACATGTGCTTCACGCAGTCCAACTCGCTGAAAGCTCACCGGCTCATTCACAATGTATCCGAGAAGCCGATGTATTCGTGCGAGCTGTGCCCGACGAAGTGCGGCCGCAAGACGGACCTGCGCATTCACGTGCAGAAGCTGCACACGTCTGACAAGCCGCTGAAGTGTCGCCGCTGCGGCAAGTCCTTCCCCGACCGCTACTCCTGCAAGGTGCACAATAAGACCCACGAGGGCGAGAAATGCTTCAAATGCGACCTGTGCCCGTACGCGTCAACCACGCAGCGCCACCTCAAGACGCACATGCTCAAACACACCGATGAGAAGCCGTTCCTCTGCGACTTGTGTGACCAGTCCTTCAGGCAAAAGCAGTTGCTTCGTCGTCACCAAAATCTGTACCACAATCCCAACTACGTGCCGAAGCCTCCCAAAGAGAAGAAGCATGAGTGCCACGAATGCCAGCGTATGTTCGCGCACAGGGGCAACCTCATCCGGCACTTGGCCGTGCACGACCCGGAGTCCGGTCATCATGAGCGCGCGCTTGCCCTCAAGATCGGACGCCAGAGGAAGGTCCGCTTCGTCGATGGAGAACCTATGAGGGATATCCGCGTCCTGGACTCAGCAGACGCCGAAAACATGATGAAGCTTGGTTTGAGCAACAACGAGCTGAAGCGCGGCGAGCTGGTGACTGTGGCCGACGGCGACGGCCATCAGTACGTGGTGCTCGAGGTCATTCAGCTCGAGGATGGCACCGAGCAGCAGGTGGCCGTCGTGGCACCTGACTTCATGGAAGGGGATGAGGGTGGTCAGTTACATTCTTAA
Protein Sequence: MPPPVKKDKNKQSLIQTYLNQGAVITVNAATDRQLDTGMVEYFVDEDGKYYYQSTVGGQVVLNSAEAAQENEEGNEASDPIMTGDDDTYQTVTFVPSESNGEVSYVLVVQDESKGGVVNIDLKVDQARENVKTEAEDKGNEDVYNFDEEEAGEEEEEDEADTEMADGTKPKVSAKTRTKHVRPNFTCNFCSYTSHRRYLLLRHMKSHSEDRPHKCSVCERGFKTLASLQNHVNMHNGIKPHVCKYCNSPFTTSGELVRHVRYKHTHEKPHKCSECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCEHCNMCFTQSNSLKAHRLIHNVSEKPMYSCELCPTKCGRKTDLRIHVQKLHTSDKPLKCRRCGKSFPDRYSCKVHNKTHEGEKCFKCDLCPYASTTQRHLKTHMLKHTDEKPFLCDLCDQSFRQKQLLRRHQNLYHNPNYVPKPPKEKKHECHECQRMFAHRGNLIRHLAVHDPESGHHERALALKIGRQRKVRFVDGEPMRDIRVLDSADAENMMKLGLSNNELKRGELVTVADGDGHQYVVLEVIQLEDGTEQQVAVVAPDFMEGDEGGQLHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00177438;
90% Identity: iTF_00041134;
80% Identity: -