Basic Information

Gene Symbol
Zfy1
Assembly
GCA_950005045.1
Location
OX465436.1:704316-709807[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.15 21 7.3 1.1 2 23 246 267 245 267 0.96
2 15 0.59 81 5.4 0.0 6 23 279 297 279 297 0.95
3 15 3.4 4.7e+02 3.0 0.4 6 23 312 330 308 330 0.90
4 15 1.1e-06 0.00015 23.5 0.6 2 23 353 374 353 374 0.97
5 15 2.8e-05 0.0038 19.1 2.6 1 23 380 403 380 403 0.96
6 15 0.0046 0.63 12.1 0.0 1 23 409 431 409 431 0.97
7 15 6.8e-06 0.00094 21.0 2.9 1 23 437 459 437 459 0.98
8 15 5.7 7.8e+02 2.3 0.7 1 9 465 473 465 475 0.89
9 15 0.0011 0.16 14.0 2.8 1 23 578 600 578 600 0.99
10 15 9e-05 0.012 17.5 4.5 2 23 607 629 606 629 0.92
11 15 1.2e-06 0.00016 23.4 1.6 1 23 635 657 635 657 0.98
12 15 1.9e-06 0.00027 22.7 4.6 1 23 663 685 663 685 0.98
13 15 0.00032 0.043 15.7 0.2 1 23 691 713 691 713 0.97
14 15 0.0013 0.18 13.8 0.2 1 23 719 741 719 741 0.91
15 15 0.00023 0.031 16.2 2.9 1 23 747 770 747 770 0.95

Sequence Information

Coding Sequence
atgaataatggaactgaacaaatatttttactaaatgCTGCCCCGAGTCAGTCTTCAGCCCCTACGCAGAGGATGGGCGCCCTAGCACCGCCGCCGATCTATCAGGTTAACCTTGAtaATGTTGAAGATTTTTCACATGTGTGTCGGACATGTGCCACTATCACGGAGTTTGTCATGCCCATATTCTCTGGCGAGGGGCTCCAGAACAACCTGGCAGACAAGATAAAGAAACACTTACCAATTCAGGTCCGCGAGGGTGATGAGCTCCCGCTGGTGGTGTGCTACCAGTGCGCGAGCACCCTGCTGGCGTGGCACGAGCTCGTCAAGTGCTGCGTGCAGGCCGACGCCGCCTTGCGTGCCAAGCTCAGCTCCAACCAGCGGaAAACAAATCCATCGAACAATGTAACCATAAAATCAAACCCAAGCATACAAGATGATCCACCAAGCAAGTTATATTACGAGAGTGTCAGGAATGCTCTTACTGACTTTCATCTGGACGAAGATGATACAGATGTTGAGTTTGTTTGTCAAAAATGTGTTGCAAAACCAGCACTGACCACTGTGTACAGCCTCGCATACCATATCCGTGACGAACATTCTCCTGAAATAATCAACAATAGTGTGCAATCATTCATCACCAACCATGTCACGTTCGAACAAATGCTAGCTGAAGATTCTGACAGAGAAACACAATCTGACACCAAAGAGAAACCACAAGTAGTTCTACCGAGCCTGCACTGTCCGTTCTGCGCAAGTGTGTTCTCGTCAGCCACGCGGTTACTGTACCATCTCAACAAACACGTGGAGGTGAGCTTAGCGGACGGAGTCACGTGCTGCGACCTCGTGTACAGCGATAAGAAACTCTTCGTGCAGCACTTGCAAGAGGCTCACGTCGATAAGACAGCGGAGGAACTAGTACAAGTGTGCATTAGCTGTGGCTTCAAGACCGACACAACTGATGAACTAAAACTGCACTATAAAGATAAACACAGCGATGTGAAAAGCACGAAAGAGAAGAAAGAAGAGAGTCCAAACAACCAGAAGTACATCCCAGCAGTGTGCCCGGAGTGCAACAAGACGTTCTCCAACAAGTACAACATGTTCGTACACCTGCGCGGCCACTCGCGGGCCGGGGTCTACCCGTGCGACAAGTGCACGCGCACCTACCGCAACCAGGGCAACCTCACCCACCACAAGAACATCATGCACCAGGGAATACTCAAGTTCATATGTGTGGAATGCGGCGAGGCCTTCCCCAGCCGCTCGGAGCGAGACATCCACGCGCGCATACACTCCGGGGAGAGACCCTACAAGTGCTCGCACTGCGGCAAGTCATACCGCGCCAAGAACACGCTCACGCGACACCTCGAGATACACGCAGACATACGAAAATATGAGTGCAAGATCTGCTCCAAAAAGAGCCCCTGCCACTCGCCTGAGGAGCCCCGAAGTGCGCATTCCGACCACTCCGAGCTGTCCGAtgacaaacacaacaaaaatctCTATTCCAACTTCTACAATGCCCTCGTAAAGTTTAGAGATCATTTTGTGAATGATCAACATCATGAGGATTATCCTGACTTCACTGACTCGAGTGTGTCGGACGCCGAGGACAACGAGGTGGACAAGTTCGACGACCTGACGCAGAACAACAAGCGCGGAGACCGGCTGGACGAGGAGACCAGGCTGGAGCTGAGAGAAGTGCAGAACAAGATCGACAACAAGACGTACTACACGTGTAAGATCTGCGGGAAGAACCTGAGCTCGACGCACACGTACCTGATCCACAAGCGCATCCACACGGGCGAGCGGCCGTGCGTGTGCCACGTGTGCGGCAAACAGTTCCGCTCGCCCAGCGGCCTGCACCGACACCTCACGGAGACACACGAGCGTCTGCGCCGGTACAACTGCAGCCTCTGCACCAAGAACTTCGCCAACTCGCAGAATCTCAAGCAGCACATGCGGATACACACGGGAGAGAAGCCTTTCGTGTGCTCGCACTGCGGGAAGAGGTTCACTCAGAGCGGAACGCTACACGTCCATCTGAAGACTCACAGCGAACAGTTCCCGTACGACTGTGCTGAGTGCGGCGCCAAGTTCAGGCTGCGCTCGGGCCTGGTGCGGCACCGGCTGAAGCACACGGGCGAGAGACCACACGCGTGCGCCGTCTGCGGCGCCGGCTTCCGCCAACGACACGAGCTGCGTGCGCACGCCGCAGCACACAGCGGCGTCGCGCCGCACGCCTGCGCCTCCTGCCCGCGCGCCTTCCGCCAGCGTCGCGCGCTGCGGCACCACATGAAGCGCGTGCACGAGGCCGAGCCGCCCGACCTCGGCCAAGCGACGTACTCGCACGTCGCGCCATACTAG
Protein Sequence
MNNGTEQIFLLNAAPSQSSAPTQRMGALAPPPIYQVNLDNVEDFSHVCRTCATITEFVMPIFSGEGLQNNLADKIKKHLPIQVREGDELPLVVCYQCASTLLAWHELVKCCVQADAALRAKLSSNQRKTNPSNNVTIKSNPSIQDDPPSKLYYESVRNALTDFHLDEDDTDVEFVCQKCVAKPALTTVYSLAYHIRDEHSPEIINNSVQSFITNHVTFEQMLAEDSDRETQSDTKEKPQVVLPSLHCPFCASVFSSATRLLYHLNKHVEVSLADGVTCCDLVYSDKKLFVQHLQEAHVDKTAEELVQVCISCGFKTDTTDELKLHYKDKHSDVKSTKEKKEESPNNQKYIPAVCPECNKTFSNKYNMFVHLRGHSRAGVYPCDKCTRTYRNQGNLTHHKNIMHQGILKFICVECGEAFPSRSERDIHARIHSGERPYKCSHCGKSYRAKNTLTRHLEIHADIRKYECKICSKKSPCHSPEEPRSAHSDHSELSDDKHNKNLYSNFYNALVKFRDHFVNDQHHEDYPDFTDSSVSDAEDNEVDKFDDLTQNNKRGDRLDEETRLELREVQNKIDNKTYYTCKICGKNLSSTHTYLIHKRIHTGERPCVCHVCGKQFRSPSGLHRHLTETHERLRRYNCSLCTKNFANSQNLKQHMRIHTGEKPFVCSHCGKRFTQSGTLHVHLKTHSEQFPYDCAECGAKFRLRSGLVRHRLKHTGERPHACAVCGAGFRQRHELRAHAAAHSGVAPHACASCPRAFRQRRALRHHMKRVHEAEPPDLGQATYSHVAPY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00712186;
90% Identity
-
80% Identity
-