Aexc019769.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agrotis exclamationis
Gene Symbol
Abtb2
Assembly
GCA_950005045.1
Location
OX465425.1:1055654-1079954[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.3e-16 8.4e-14 53.2 0.0 7 105 1455 1562 1451 1567 0.85

Sequence Information

Coding Sequence
ATGCTGTGCCCCGCGCGTTGCTCGTGCTTCCTCTGCCGCGAGCTGCAGTCCTGCCGCGCCGCGGACGCCAGAAAACCTAACAAAAACAACATGTGCGACAACTTCATACTCAAGAAGGCGGAGGCGTGGGAGCCCATGAAGTTCATTCGCGGAGCCGCGCGCATGTCCGTCCGCCACTGGCAGAGCAGGGACCCGCTCACCTCCAACAAGACGAGGGTCGCGACGCACAAGTCCACCAGCTGCGAGCAGCTATACCCGCACCCCTCCGAGGACGAGTCGGGACCGTTCGGCATGCGGCGCGCACCCAGCACCGACCGGGTCAAGCCGCAATCGGAACACAAGGCTCTGTTCAAACTCCTCGGGAATTCCCGGAATAAGAAAACGAACATCAGTGATGCTTCGGAATCAAAAGTACGTCGAAGTGTTCTGAATTTCAGAAAGACTGAAGCCCCTTCAAAGAATGTTCATGAAAAGTACATTCCTTTGCCGCAGGTGTCATCGCCCACGGAACATATTTATAGTGAACCTCGATCCTCCGTAAGGAACCCACAGTCTTCCCAGTTCGACGAGTGTTGTCGACCGCCGGTATACCAGAGCGTGGAAAAGAGGAAGGAAGAGCTCAACAAGTGCTCTGCGGACAAAAAGGTTTACAGCAACCGCCTTCCGTGTTACGAGGAATTAGCGCAGAGACTTTCCCAGGAAAAGATCAAAAAAGCTAACTTACCTCTTACGGAAGGAGGATTAGCAAATAAGATcacacagaataataataaagttgtGATTTATTTTGGCGATTCAATAATTCGCAAACATAATGAGCAAAAGAAAGAAGAATATCGACTCAAAGAGGAGCCCGCTAAGGAAGAAGTTATTTATGCCAATAGACTTTTAGAAGAAACGGGCAACTTGGGACTGAGTAGAGAAGTAGATAGAGGTGGAGGTAATACACAGATGGTATCTGAAGTTCAGGTTCCAGAAGCTATTTATTCTGAGATTAAGGCTGATGAAAGTAAAGACACTCTCGACGTCGTGACGATTAACGATGCGACGTACAAGAAGGATGTGTTTGGAACTATGAGTTCTGATGGGTTCCTAGTGGTTGAGTTTGAGGGGAATTTCGAAAGAGCTCGGCAGCTGGTTGAGCTGGTGCATGGAGGTGGGGTGGATCATCACGAGGCTACAGTGCTTGACGAAGATGAGCACTGTGACTGGAGTTTCATCCAAGACTGGAGGAAGCGGCCATCAAGCGGCTGTCGTCCATCAGAGGAGGGGGCGTGGTGCGGCGGCGTGTCGGGCGCGCGGGCACTGCGCGTGCGCGTGAGCGGGGCAGCGGCCGCCCCCGCGCCCGCGCACGCTCGCCGCCTGTCGCCGCCGCCGCACGCGCACCGAGCCACCACGCCGCCCAGGCCTACCTCACCCACCAATAAACCCATCCACGAAGAGCCCCCACCGCCATCAACAGATGGCCCCAGCTCTGCGCAGCTGAAGGCAGTGGGCGCGGTGTCCCAGCTGACCGTGGCCAGCGCGCCCGTCCGCAGTGCGCCCGCGCAGAACAGCTATGCGCTGGAGCGGCGCCCGGCGAAGCACGACCATCACCATAGGCCGGTTGAAACAGCACCACCAGTACAGAATGGCGTTCGTGAATGCAACAGCAGTTCGGACGAGAACAGGTCGTCCGGGCACGCGTCCATGTCGGACAGCGGGGGCGGCGGAGAGGCGGGCAGGGAGGAGCCGCGCCGGACACGCCAGCCGCCGCACGCCCGGACTAAGCATCGACCACATAATAAGTTACAGTCCCCATGGCCTGGAGGCGGGGGTCTGGAGGACATCAGGTCAGCTATCAAGCAGCTGACACTTCGCTCCAGAGACAGTAGCAGCACCGCCACGAGTGCTTCCAGTGCCGGTGGTGGCAGCAATAATGGAGCTCAGGAGAGTGGAAGTGCAGCCGAGGCTCGCAGGAGACGAGCTCCGCTGGTGAGACAGCCTTCACTGGACACCGTCTGCACAAACGTTACCAGTGCCGATGAGTTCGTGTGGGTGGACTCGCATAACAGGCTGGTGGAACTTCGTTGTGTGCCCTGGACAGCGAGTGAGGTCAGTCGAGCGCTACAAGCTGGAAGGTGCCGAGATATCGCACCCAGGATGGCACCAGACACACCTTCGAGACTCGCCTACTTACTACAAAGGGCACTAGTAAGAATAGCCCGTGAAGCGCAGCGTCTCTCCCAAAACTTCGGCTTCTGCTCCAAGCATGAAATAGCTGGTGCGTTCAGGATAGTACTCAGCACGCCGCTTGCTGACGCTTGCATTAAGGGTTGCCAACGAGCAGCGACAATGTACGCGACTTCAGGTAGTGCTGCGAGACGCCTCGGCTCAGCAGCTCGGGCACGGACCAGCCTCGCACCAGGGCGGTTCCAGAGATGGATGCTGGATGTCCGTGTCGCGTCGTTTGTGCACGAATACGCAGCTATCTATCTCTGCGCTGGTATGGAGACGCTGCTAGAGGAGATCGCACTGATAGCCGGCAGCAGCGCCGCCACCTCGCCTATCACACCGGCTGTGGTCGACCACGCCGTCGCCAACTGCGCTGATCTCTGGGGACTGCTGCAGCCTTACAGCCATTTGAATGCTGGAAGAGTCGCTTCAGGTGCATTATCACTGTCTCGTTGGGAATCCATGAGCTCGCTGGGTTCCGGGTCATCATCAGGAATATCCCGTCCTGAACATAGAGCGTTGGGTCTGAGTCACGATTCTGGTATCACTACTAACGGTTCTGGTGGTTCTGGAACCTCAGCTGGCTCAAACAACAGTTCTGGTGGTTCGACGGCATCAGTTCTGTTGACCACGTGTGCTGGCTCCGCGTCAGAGCTGCGAGCTGTGTTGCGGAGAGTACACCCGCGGCTGCCACCCCTGTCGCCTGCTGCTGAAAGAGCGTTGTACTACTTTATGAGATGCTCTCAGTTGGAGCACTCGAGCACGAGCGGCAGCTGCGGCGGCGCGGGGCTGTGGGGcgagcgcggcgcgggcgcactgCCGCCGCTGGGCGAGTGGGTGCGTGTGCTGCGCGCGCACGCCGCGCTACGTCCGCCACCCGCCGTGCCCGACGCTGATGACGTCATGCAGGCTGCCAGGCTGCTGCTGCCGCATGCCGACTGCCCGCCAAGACCTATCacCTTAGAAGACGCCATAGAGCCAGTTTGGTCCCGCTGCGCGCGCACGGCGGACGAGCTGAGCCGGGCAGCCGTCGGCGTCGCTCAGCGGGCCCTGCTCAGCGGGAGACCGGAGCTGGTGGGCGGCGTGCGGGCGCTGCTGCCGCCAGCTGGCATCGACGCACCTGACGCCTCGGGGCTGACAGCGCTCATGAAAGCGGCGTTTGCTGGCGATGAGCAGATTGTGGCTATGTTGCTAGAAGCGGGCGCGGACCCCAACATCGAGACAGGCGGCGCGTGCGCAGCCCACTGCGCACTGCCGCTGTCACCGCGGTCACCATCCACGCAACAAACAACCCCTACCTATACACCACCCACTGCAGGTTGGACAGCACTTGTGTACGCGTGCAGTGGCGGTGGAGGTGGCGCCGTGGAGTGCGCACGCCGCTTGATTTCTGCGGGtgcccgggtagacggcgcgCCAGCCCGGGGAGACGATGTTTGCACTCTAACGCCTCTACAAGTGGCCTGTGGCGTCGGTAACTTAGAGCTCGTACAGTTATTATTGTCACATGGCGCAGACCCGTTCCTGTCAACACAACTTAATGATGCCTTGTGCTACTCCGCCGCTGCACAGTATGGGTGTTACAGTGCGGTAGCCGTATGCTGTGCACATGGACGCCGTGCGTGCTTGCGTGCAGCAGTTCGTGGTGGAGCGCGAGGAAACGCTCAAGCTGTGTTGTCACTGGAGGAAGTTCTGGCTGAGGGTGCAGCTGCACCACCTGTAAGACACCCCGCCTTCACCAAACAGCAGCAGAGGGCGTTGCATGACGCCATGTACTGTGCCGCTGAGACTGATCATTTGGACATTACATTAGAACTACATGCGCTAGGCGTACCATGGTCACTGCACGCGTGGACTTTATCTCTAGCAGCCGCCGCAGACGCAGCACTTGATAGTGTTATTGACCAACTGCTACAAGACTTTCTACAGGTGTGTCCATCAGACGACAGCCACTACAGTAAACAGTTCATTTACGAATGCCTCCCCCTGCTGTTTAATATTCTACGATACAGCAAGAAGGAAGGCACTGTCTTACTGCTGGCTGATATCCTGTGCGCATGTTACGGACGGGAGCCCGTGCCGGGCGTAGCGCAACCACCTCCTCCTGTTGCGCCGGCACCTGCCAGGGTTGACCCCTCCTACGTCAACAATCCTTCACTTGCTGATGTCACGTTCAGGGTTGAAGGACGACTGTTCTATGGCCATAAAATAGTCCTTGTCTCGGAGTCAGCACGCTTACGAGCAATGTTAGCTCCTGCCAGATCATCGAATGAAGCCTTACCGGTCGCCAACGCAGCCCCACCGCTTGTACAAATTAACGATATCCGGTATCACATATTTGAGCAAGTGATGAAGTATCTCTACTCGGGTGGATGCACAGGATTAGACATCCCTGAGGTAGACGTATTAGAGGTACTAGCCGCCGCCTCCTTCTTCCAGCTTCTGCCGCTACAGAGGCACTGTGAGGCGAGAGCGGCCAAGTCTGTGGACTTACACAACCTCGTCTCAGTCTATATTCATGCTAAGGTTTACGGTGCTACTCAACTGTTGGAATACTGCCAGGGATTTCTACTTCAAAACATGGTCGCTCTTCTAACGTACGATGATTCCGTTAAGCGGTTGCTCTTCGGAAAACGATTACCCGGACATAATGTTCTTGGTGCTTTATTGGtaactttacaaaaaagaaTCGAAGCCAGAAAGAACCAAGCGAAAAatagataa
Protein Sequence
MLCPARCSCFLCRELQSCRAADARKPNKNNMCDNFILKKAEAWEPMKFIRGAARMSVRHWQSRDPLTSNKTRVATHKSTSCEQLYPHPSEDESGPFGMRRAPSTDRVKPQSEHKALFKLLGNSRNKKTNISDASESKVRRSVLNFRKTEAPSKNVHEKYIPLPQVSSPTEHIYSEPRSSVRNPQSSQFDECCRPPVYQSVEKRKEELNKCSADKKVYSNRLPCYEELAQRLSQEKIKKANLPLTEGGLANKITQNNNKVVIYFGDSIIRKHNEQKKEEYRLKEEPAKEEVIYANRLLEETGNLGLSREVDRGGGNTQMVSEVQVPEAIYSEIKADESKDTLDVVTINDATYKKDVFGTMSSDGFLVVEFEGNFERARQLVELVHGGGVDHHEATVLDEDEHCDWSFIQDWRKRPSSGCRPSEEGAWCGGVSGARALRVRVSGAAAAPAPAHARRLSPPPHAHRATTPPRPTSPTNKPIHEEPPPPSTDGPSSAQLKAVGAVSQLTVASAPVRSAPAQNSYALERRPAKHDHHHRPVETAPPVQNGVRECNSSSDENRSSGHASMSDSGGGGEAGREEPRRTRQPPHARTKHRPHNKLQSPWPGGGGLEDIRSAIKQLTLRSRDSSSTATSASSAGGGSNNGAQESGSAAEARRRRAPLVRQPSLDTVCTNVTSADEFVWVDSHNRLVELRCVPWTASEVSRALQAGRCRDIAPRMAPDTPSRLAYLLQRALVRIAREAQRLSQNFGFCSKHEIAGAFRIVLSTPLADACIKGCQRAATMYATSGSAARRLGSAARARTSLAPGRFQRWMLDVRVASFVHEYAAIYLCAGMETLLEEIALIAGSSAATSPITPAVVDHAVANCADLWGLLQPYSHLNAGRVASGALSLSRWESMSSLGSGSSSGISRPEHRALGLSHDSGITTNGSGGSGTSAGSNNSSGGSTASVLLTTCAGSASELRAVLRRVHPRLPPLSPAAERALYYFMRCSQLEHSSTSGSCGGAGLWGERGAGALPPLGEWVRVLRAHAALRPPPAVPDADDVMQAARLLLPHADCPPRPITLEDAIEPVWSRCARTADELSRAAVGVAQRALLSGRPELVGGVRALLPPAGIDAPDASGLTALMKAAFAGDEQIVAMLLEAGADPNIETGGACAAHCALPLSPRSPSTQQTTPTYTPPTAGWTALVYACSGGGGGAVECARRLISAGARVDGAPARGDDVCTLTPLQVACGVGNLELVQLLLSHGADPFLSTQLNDALCYSAAAQYGCYSAVAVCCAHGRRACLRAAVRGGARGNAQAVLSLEEVLAEGAAAPPVRHPAFTKQQQRALHDAMYCAAETDHLDITLELHALGVPWSLHAWTLSLAAAADAALDSVIDQLLQDFLQVCPSDDSHYSKQFIYECLPLLFNILRYSKKEGTVLLLADILCACYGREPVPGVAQPPPPVAPAPARVDPSYVNNPSLADVTFRVEGRLFYGHKIVLVSESARLRAMLAPARSSNEALPVANAAPPLVQINDIRYHIFEQVMKYLYSGGCTGLDIPEVDVLEVLAAASFFQLLPLQRHCEARAAKSVDLHNLVSVYIHAKVYGATQLLEYCQGFLLQNMVALLTYDDSVKRLLFGKRLPGHNVLGALLVTLQKRIEARKNQAKNR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00044674; iTF_01534114; iTF_00926788; iTF_01180452; iTF_01208452; iTF_00281541; iTF_00822131; iTF_01075668; iTF_00823191; iTF_01360856; iTF_00677817; iTF_00928869; iTF_00042822; iTF_01062038; iTF_00827174; iTF_00825979; iTF_00897030; iTF_01080870; iTF_01506508; iTF_01508219; iTF_01507373; iTF_01080048; iTF_01209478; iTF_01386886; iTF_00377255; iTF_00673639; iTF_00737639; iTF_00831399; iTF_00121619; iTF_01247280; iTF_00037982; iTF_00844551; iTF_01501327; iTF_00953703; iTF_00703177; iTF_00704179; iTF_00705214; iTF_01063913; iTF_00143210; iTF_01246090; iTF_01385962; iTF_01363275; iTF_00209036; iTF_00290860; iTF_00819336; iTF_01430088; iTF_00063758; iTF_00787833; iTF_00638796; iTF_00699404; iTF_00663245; iTF_01062989; iTF_00806894; iTF_00994504; iTF_01337040; iTF_00275483; iTF_01179630; iTF_01173448; iTF_01417006; iTF_00267375; iTF_00642511; iTF_00802063; iTF_01439184; iTF_01504048; iTF_01124753; iTF_00325586; iTF_01134964; iTF_00341490; iTF_00858735; iTF_00027027; iTF_01533235; iTF_01416052; iTF_00007282; iTF_01083517; iTF_01528468; iTF_00006421; iTF_00948053; iTF_00043734; iTF_00250646; iTF_00685622; iTF_00700278; iTF_00706214; iTF_00701236; iTF_01085558; iTF_01535094; iTF_00621367; iTF_00683511; iTF_00035894; iTF_01335158; iTF_00300408; iTF_01230793; iTF_00120687; iTF_01119537; iTF_00888435; iTF_01118488; iTF_01026494; iTF_01028479; iTF_00952000; iTF_00036993; iTF_00039009; iTF_00147681; iTF_00810273; iTF_00273775; iTF_00274578; iTF_00809332; iTF_01342371; iTF_00783689; iTF_00364204; iTF_01340384; iTF_00785357; iTF_01192878; iTF_00772177; iTF_01440247; iTF_00447416; iTF_00445373; iTF_01081752; iTF_01444057; iTF_00923002; iTF_00076731; iTF_00075706; iTF_01064827; iTF_01220795; iTF_00033980; iTF_01487868; iTF_00186440; iTF_01076697; iTF_01538939; iTF_00050110; iTF_00302301; iTF_00301365; iTF_00323645; iTF_00365085; iTF_00017502; iTF_00018326; iTF_00318238; iTF_00410494; iTF_00077663; iTF_00720511; iTF_00834815; iTF_00896095; iTF_01073759; iTF_00622143; iTF_01171615; iTF_01170746; iTF_00342368; iTF_00724096; iTF_01282528; iTF_01464320;
90% Identity
iTF_00039009;
80% Identity
-