Basic Information

Insect: Agrotis clavis
Gene Symbol: CTCF
Assembly: GCA_954870645.1
Location: OX940917.1:34885640-34906539[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.014 1.7 10.7 4.9 1 23 183 205 183 205 0.98

2 11 3.4e-05 0.0042 18.9 1.3 1 23 211 233 211 233 0.98

3 11 9e-05 0.011 17.6 1.7 1 23 239 262 239 262 0.96

4 11 0.042 5.2 9.1 3.2 1 21 268 288 268 290 0.95

5 11 0.00013 0.016 17.0 2.7 1 23 296 318 296 318 0.99

6 11 1.8e-05 0.0022 19.7 5.3 1 23 324 346 324 346 0.98

7 11 0.0041 0.51 12.3 0.9 1 23 354 377 354 377 0.97

8 11 0.022 2.7 10.0 4.3 2 23 384 405 383 405 0.96

9 11 5.9e-05 0.0072 18.1 2.9 1 23 411 433 411 433 0.98

10 11 2.4e-05 0.003 19.3 1.7 1 23 439 462 439 462 0.93

11 11 8.5e-05 0.011 17.6 4.2 1 23 476 498 476 498 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.014	1.7	10.7	4.9	1	23	183	205	183	205	0.98
2	11	3.4e-05	0.0042	18.9	1.3	1	23	211	233	211	233	0.98
3	11	9e-05	0.011	17.6	1.7	1	23	239	262	239	262	0.96
4	11	0.042	5.2	9.1	3.2	1	21	268	288	268	290	0.95
5	11	0.00013	0.016	17.0	2.7	1	23	296	318	296	318	0.99
6	11	1.8e-05	0.0022	19.7	5.3	1	23	324	346	324	346	0.98
7	11	0.0041	0.51	12.3	0.9	1	23	354	377	354	377	0.97
8	11	0.022	2.7	10.0	4.3	2	23	384	405	383	405	0.96
9	11	5.9e-05	0.0072	18.1	2.9	1	23	411	433	411	433	0.98
10	11	2.4e-05	0.003	19.3	1.7	1	23	439	462	439	462	0.93
11	11	8.5e-05	0.011	17.6	4.2	1	23	476	498	476	498	0.97

Sequence Information

Coding Sequence: ATGCCACCTCCTGTTAAAAAGGATAAAAACAAGCAATCGCTTATCCAAACATACTTAAACCAAGGAGCAGTCATCACGGTCAACGCCGCCACAGATAGACAGTTAGATACTGGAATGGTGGAGTATTTCGTAGATGAAGACGGCAAGTACTACTATCAGTCAACTGTTGGAGGGCAGGTGGTCCTGAATAGTGCTGAAGCTGCCCAAGAAAATGAGGAGGCTGCTGAAGCTTCGGACCCAATTATGACCGGCGACGACGATACTTACCAGACGGTCACCTTCGTCCCCTCTGAGAGCAATGGGGAAGTGAGCTACGTGCTAGTAGTGCAAGATGAGAGCAAGGGTGGCGTTGTCAACATTGATCTCAAGGTGGACCAGGCACGGGAGAACACCGAAGCAGAGGATAAAGGCAACGAGGACGTGTACAACTTCGATGAGGAGGAGGCCggagaggaggaggaggaggatgAAGGAGACACGGAGATGGCAGACGGCACTAAGCCCAAGGTGTCGGCCAAGACACGCGCCAAGCACGTGCGCCCGAACTTTACGTGCAATTTCTGCGCTTACACTAGTCATCGCCGGTACCTCCTCCTGCGCCACATGAAATCACACTCGGAGGACAGGCCTCACAAGTGCAGCGTGTGCGAGCGCGGCTTCAAGACGTTGGCCTCGCTGCAGAACCACGTCAACATGCACAACGGCATCAAGCCGCACGTCTGCAAGTACTGCAACAGCCCCTTCACCACCTCGGGCGAGCTGGTGCGTCACGTGCGCTACAAGCACACGCACGAGAAGCCGCACAAGTGCTCGGAGTGCGACTACGCGTCTGTGGAGCTGTCCAAGCTGCGTCGCCACGTGCGCTGCCACACCGGCGAGAGGCCCTATCAGTGCCCGCACTGCACGTACGCGTCGCCGGACACGTTCAAGCTGAAGCGCCACTTGCGCACCCACACCGGCGAGAAACCATACAAGTGCGAGCACTGCAACATGTGCTTCACGCAGTCCAACTCGCTGAAAGCTCACCGGCTCATTCACAATGTATCCGAGAAGCCGATGTACTCATGCGAGCTGTGCCCGGCCAAGTGCGGCCGCAAGACGGACCTGCGCATCCACGTGCAGAAGCTGCACACGTCTGACAAGCCGCTGAAGTGCCGCCGCTGCGGAAAATCCTTCCCTGACCGCTACTCCTGCAAGGTGCACAATAAGACTCACGAGGGCGAGAAATGCTTCAAGTGCGACCTGTGCCCGTACGCGTCGACCACGCAGCGTCACCTCAAGACGCACATGCTCAAGCACACCGATGAGAAGCCGTTCCTCTGCGACTTGTGTGACCAGTCCTTCAGGCAAAAGCAGTTACTCCGTCGTCATCAGAACTTGTATCACAATCCGAACTACGTGCCGAAGCCTCCCAAAGAGAAGACGCACAAGTGTCACGAGTGCCAGCGCCTGTTCGCGCACAAGGGCAACCTCATCCGGCACCTGGCCGTGCACGACCCGGAGTCCGGCCACCATGAGCGCGCGCTCGCTCTCAAGATCGGACGCCAGAGGAAGGTCCGCTTCGTTGATGGGGAGCCTATGAGGGATATCCGCGTTCTGGACTCAGCGGACGCCGAGAACATGATGAAGCTTGGTCTGACCAACAACGAGCTGAAGCGCGGGGAGTTGGTGACTGTGGCCGACGGCGAAGGCCATCAGTACGTGGTGCTCGAGGTCATTCAGCTCGAGGACGGCACTGAGCAACAGGTTGCCGTTGTGGCACCCAACTTCATGGAAGAGTATGAGGCTGAAGAGgaagaggaggaggaggaggaagaagaagaagaagaagaggaagaagaggaggaggaggaggaggtgAAGAACAAGAGTTTTGTTGTGAAGAAAGGAGGCCAGAATGCCACCAACACCCTCTCTACGCAGAGCATTAAACTCGAGCAGGAGGTCGACACCTGCTTTGGATTTGATGAGGAGGAAGAAGAGCCTGATGACGTTGATGTTGATGTCAACTATACGGACAAAGTCGTGTTGCGCTTAGTTTAG
Protein Sequence: MPPPVKKDKNKQSLIQTYLNQGAVITVNAATDRQLDTGMVEYFVDEDGKYYYQSTVGGQVVLNSAEAAQENEEAAEASDPIMTGDDDTYQTVTFVPSESNGEVSYVLVVQDESKGGVVNIDLKVDQARENTEAEDKGNEDVYNFDEEEAGEEEEEDEGDTEMADGTKPKVSAKTRAKHVRPNFTCNFCAYTSHRRYLLLRHMKSHSEDRPHKCSVCERGFKTLASLQNHVNMHNGIKPHVCKYCNSPFTTSGELVRHVRYKHTHEKPHKCSECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCEHCNMCFTQSNSLKAHRLIHNVSEKPMYSCELCPAKCGRKTDLRIHVQKLHTSDKPLKCRRCGKSFPDRYSCKVHNKTHEGEKCFKCDLCPYASTTQRHLKTHMLKHTDEKPFLCDLCDQSFRQKQLLRRHQNLYHNPNYVPKPPKEKTHKCHECQRLFAHKGNLIRHLAVHDPESGHHERALALKIGRQRKVRFVDGEPMRDIRVLDSADAENMMKLGLTNNELKRGELVTVADGEGHQYVVLEVIQLEDGTEQQVAVVAPNFMEEYEAEEEEEEEEEEEEEEEEEEEEEEEVKNKSFVVKKGGQNATNTLSTQSIKLEQEVDTCFGFDEEEEEPDDVDVDVNYTDKVVLRLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00301464;
90% Identity: iTF_00041134;
80% Identity: -