Basic Information

Insect: Agrochola lota
Gene Symbol: Hr39
Assembly: GCA_947364205.1
Location: OX376221.1:4888942-4912921[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.11 9.2e+02 -0.6 4.4 69 186 219 335 129 367 0.58

2 3 4e-08 0.00034 20.6 0.1 1 21 444 464 444 480 0.90

3 3 1.2e-64 1e-60 206.8 0.0 152 408 497 763 473 763 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.11	9.2e+02	-0.6	4.4	69	186	219	335	129	367	0.58
2	3	4e-08	0.00034	20.6	0.1	1	21	444	464	444	480	0.90
3	3	1.2e-64	1e-60	206.8	0.0	152	408	497	763	473	763	0.85

Sequence Information

Coding Sequence: ATGGTGATGAGCACCGCGATGAGCAGTGAGGGCGACGCGGTGAAGGTGGAGGGGGGACACGTATCTGTCACCACTATCAGCATGTCGGGCCCGGAGACTAGCAACGGTCAGTTCTCGTACAGCTCGAGCGGCGTGCGCATCAGTGTGTCTTCAGTGCCTCATGATGAAGACTCCACTGACGCCGAGATCTCCAAGATCGACTTCTCACAACATCAGTACGAGGTGAACATGCGTAATAAGAAGAAGCGTTCATTGGGCGGCGCGCACGAAGTCGCCAGCAATGAGCGCGAACGACCCATGTCCTGGGAGGGCGAGCTGTCAGACTCCGAGATGGTTATAGATACCAGTGTAAATAATGACGAGACCAACAGCTCTCTAGACCTCCAGTCATCGAGAGACTCAATCGACACGCTCCGCAATGTAAGCATCAAGACCGAACCCGTCAAGACGGAGGGCTTCCAGAGCTTGGACGAGCAGCGGGTCCTGGACCTGAAGTATAGCGCGCCGCTGCAGCCGCACCAGAGGAGTCTTAGTATGAATAGGATATCAGTGCTAACGGACGGCACAACACTCTCTCTAGCAAGACGCCCGTCTTCTCCGACTAGTAGTGCCAAGTCCCTCGCACTGAGCGACCAAGGCTCAAACCACATGCCACATACCGGCTTGGATCAAGTACAGAACTTGACTATCAAGAAGGAGACACAGTTATCTGAGTTAAAATGCGAGCAGTCAGTGGGTATGGACAAGCTGATCGGCGCGCTGCACGGCTCGCCACTGCTGGGCCGCCTGCCGCGCGTGCAGTCCAGTGCCAGCACGGACTCTGCAGTGCACTCTATGTATACACACAGTGTATACAGCAGTCCATCAGCGAGTCCCCGCGCGTCCCGGCACTACACGCCGTCGCTGTCGCGCAACAACAGCGACGCGTCGCATTCCTCCTGCTACTCGTACAGCTCCGAGTTCTCGCCCACGCACTCGCCAGTACAGGGTCGGCACCCACATGTGATGTACCGCGAGGCTGCGCCAGCGTACGACGGCACACATGACGACGAGCCCGACGCGCCTGAAGACAGGCTACATCATCATCAGGGTATCAGCAGACAGCAGCTTATTAACAGTCCATGTCCAATCTGCGGCGACAAGATCAGCGGCTTCCACTACGGCATCTTCTCGTGCGAGTCTTGCAAGGGCTTCTTCAAGAGAACAGTTCAGAACCGCAAGAACTACATGTGCTTGAGGGGGGGCAACTGTCCCGTAACTGTGACTACGAGGAAGAAGTGTCCTGCGTGTAGATTTGATAAGTGTCTGGGGTGCGGGATGAAGCTTGAAGCTATCAGAGAAGACCGCACCCGCGGCGGCCGCTCCACGTACCAGTGCTCCTACACGCTGTCGGGCGCCGCGTCCACGGGCTCGCTGCTGGCGCCGCACGCGCCCGCCACGCTGCGCCACGCCTCCAGCCTCACGTGTGTTAACGGTCCCGGATCATACAGCAGCAGAGGAGAGTCCAGTAACAGCCAAGTTACACCAGATATACCGCCATTATTACAGGAAATAATGGACGTGGAACATCTGTGGCAGTACAACGAGTCGGAACTGAGCAGGCTAGGCAAGTCCACCGGCGGCAGTCCTTCTGCCAACCCCCTGCTAGCCGCGAGCGGGATCACGGCACATAACTCCAGCCCCGACTTCCTGGCTGACCTGTGCAATATAGCTGATCATAGATTATACAAGATTGTGAAGTGGTGCAAGAGTTTGCCGCTTTTTAAGAATATTTCGATCGACGATCAAATCTGCCTGCTGATCAATAGCTGGTGCGAACTCCTGGTACTGTCGTGTTGCTACCGCGGCGTCAGTACTCCGGGTGAAGTACGAGTTGGTGGGGGACGTGGCATCACGCTGCATCAGAGTGccaaACTGGGTCTGACGCCGTGTATCGAGCGCATGCTCAGCTTCACGGACCACCTCCGGAGGCTGCGCGTGGACCGATACGAATACGTGGCGCTCAAAGTTATTGTACTACTCACTTCAGACGCCCCAGATTTACGTGAAGTGGAGAAAGTACGAGCTTCCCAAGAGAAAGCGTTGGCAGCACTGCAGGCATACATCGCGACACACTCCCCCGGCACGCCGGCCAAGTTCGGAGAACTGCTGCTGCGTATACCTGAACTGCAAAGGACTTGTCAGTTTTTCATGCAAGTCGGCAAAGAAATGCTGAACCCAGCCAACAAAAGCAAAGATGGCGACGGACCCAGCTTCAATTTACTCATGGAACTGTTGCGCGGCGACCATTGA
Protein Sequence: MVMSTAMSSEGDAVKVEGGHVSVTTISMSGPETSNGQFSYSSSGVRISVSSVPHDEDSTDAEISKIDFSQHQYEVNMRNKKKRSLGGAHEVASNERERPMSWEGELSDSEMVIDTSVNNDETNSSLDLQSSRDSIDTLRNVSIKTEPVKTEGFQSLDEQRVLDLKYSAPLQPHQRSLSMNRISVLTDGTTLSLARRPSSPTSSAKSLALSDQGSNHMPHTGLDQVQNLTIKKETQLSELKCEQSVGMDKLIGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVMYREAAPAYDGTHDDEPDAPEDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVTTRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLAPHAPATLRHASSLTCVNGPGSYSSRGESSNSQVTPDIPPLLQEIMDVEHLWQYNESELSRLGKSTGGSPSANPLLAASGITAHNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLREVEKVRASQEKALAALQAYIATHSPGTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042698;
90% Identity: iTF_01076559;
80% Identity: iTF_00037925;