Alit001704.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agrochola litura
Gene Symbol
mod(mdg4)
Assembly
GCA_949152395.1
Location
OX424490.1:25286314-25287427[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 9.8e-28 6e-25 89.0 0.1 2 99 23 116 22 125 0.92

Sequence Information

Coding Sequence
ATGGCGTCGGACGAACAATTTTCACTATGTTGgaacaatttccacgcaaacatGTCAGCAGGCTTTCACGGCCTGCTGTCGCGTGGAGATCTAGTAGATGTTACGCTGGCTGCCGAAGGCAGATTATTACAGGCACACAAATTAGTCTTATCAGTATGTTCTCCTTATTTTCAAGAGATGTTCAAAATGAATCCCACACAACATCCCATAGtatTTTTAAAAGATGTTAGTCATTCAGCGTTAAGAGACTTATTACAGTTTATGTACCAAGGTGAAGTTAATGTTAAGCAGGAAGAGTTAGCATCGTTTATTAGTACCGCGGAACAGCTTCAAGTGAAAGGTCTAACCGGAAATCAAAATGAAGAAAGTTCCACGCCATCCAAACCAAAGCCGACCTCTAGGCCAGGCCCGAGGTCGTCACAACAAAGGCAATCATCCGTTATGACTAAGTTAGAGACTGATTTAGATTCTAAGCCCTCCACCACTCCAGTAGCGGTTAAGCGACCAAATAGGCCATCAATAGCGTCAAATAATTCGTCGTCTTCACAAAGTGGAcctgcgaaacgaaaatgtgtGGACCCATTAGAAGCCGGACCGTCAGGATCAGCGAAAGAGGAATTTGTGACGATACCTGATGAGGACGAAAACAACGCCGTGGCACCTAAAATGGAACCTGAATTCGTAAATGAAAGTATGTGGGACGACGACGATGATGGCGCTAACAATGAGGAAACCAATTTCGGCGAAGATGACTCTAATATGGAAATGACTGGCTTTGATGGCTCTACGACTGGTGATGGCAATATAACTGGAGGCGGTGAAGGTGGAGCAGTTGGAGATGCACAAGGTAGGTTTGCAACTTCCTTTTGTAAAGACAGTTCGTCCAAGTCCCCTATTCTTGGACTAGCTGTCTCGTAA
Protein Sequence
MASDEQFSLCWNNFHANMSAGFHGLLSRGDLVDVTLAAEGRLLQAHKLVLSVCSPYFQEMFKMNPTQHPIVFLKDVSHSALRDLLQFMYQGEVNVKQEELASFISTAEQLQVKGLTGNQNEESSTPSKPKPTSRPGPRSSQQRQSSVMTKLETDLDSKPSTTPVAVKRPNRPSIASNNSSSSQSGPAKRKCVDPLEAGPSGSAKEEFVTIPDEDENNAVAPKMEPEFVNESMWDDDDDGANNEETNFGEDDSNMEMTGFDGSTTGDGNITGGGEGGAVGDAQGRFATSFCKDSSSKSPILGLAVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01028450; iTF_00185444; iTF_00758405; iTF_00124421; iTF_00374347; iTF_00374348; iTF_01093266; iTF_00924915; iTF_00123515; iTF_00147654; iTF_00831367; iTF_00237896; iTF_00374346; iTF_01117482; iTF_01527466; iTF_00364171; iTF_00364172; iTF_00745932; iTF_00122550; iTF_01441228; iTF_00071630; iTF_00273742; iTF_01095087; iTF_01192847; iTF_00345943; iTF_00345944; iTF_00786925; iTF_00925864; iTF_00761809; iTF_00839538; iTF_00851952; iTF_01119506; iTF_00301331; iTF_00425587; iTF_01094186; iTF_01247251; iTF_01247252; iTF_00120664; iTF_00120665; iTF_00111796; iTF_00173204; iTF_01197908; iTF_00040021; iTF_00622969; iTF_00121594; iTF_01197914; iTF_01339066; iTF_01340356; iTF_00712059; iTF_01526203; iTF_00375452; iTF_00375451; iTF_00952828; iTF_01031260; iTF_00667677; iTF_00302270; iTF_00850910; iTF_00906303; iTF_00951967; iTF_00177312; iTF_00907168;
90% Identity
iTF_00041026; iTF_00786116; iTF_01340356; iTF_00124421; iTF_00758405; iTF_00374347; iTF_00374348; iTF_00071630; iTF_01095087; iTF_01192847; iTF_01093266; iTF_00121594; iTF_00667677; iTF_00147654; iTF_00171974; iTF_00831367; iTF_00237896; iTF_00374346; iTF_01094186; iTF_01117482; iTF_01527466; iTF_00364171; iTF_00364172; iTF_00745932; iTF_01441228; iTF_00273742; iTF_01119506; iTF_01533202; iTF_01532240; iTF_00301331; iTF_00425587; iTF_00924915; iTF_01247251; iTF_01247252; iTF_00120664; iTF_00120665; iTF_00111796; iTF_00173204; iTF_00122550; iTF_00823158; iTF_00622969; iTF_01339066; iTF_00123515; iTF_00712059; iTF_01062009; iTF_01526203; iTF_00375452; iTF_00375451; iTF_00677788; iTF_00144769; iTF_00144770; iTF_00256068; iTF_00358755; iTF_01569476; iTF_00115056; iTF_01388624; iTF_01385927; iTF_01387726; iTF_01386847; iTF_00839538; iTF_00923827; iTF_00689496; iTF_01206685; iTF_00037950; iTF_00302270; iTF_00906303; iTF_00907168;
80% Identity
iTF_00364171;