Astr003945.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agriphila straminella
Gene Symbol
BAZ2B
Assembly
GCA_950108535.1
Location
OX467304.1:16026022-16070255[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 5.5e-09 2.5e-05 24.8 0.0 3 75 434 509 432 511 0.85
2 2 5.4 2.5e+04 -4.0 0.0 13 19 1929 1935 1925 1937 0.82

Sequence Information

Coding Sequence
ATGTCATGTCTTCTTATTGCTCTGACTCGAAATACCTATGAACAATTTCCACTCGCAGGTCGCAAACCCTCCAGCCAATCGTCATCTTCTAAGGGCAAGGAGCGCGACTTAGCGCTACTACGGGGCGACCTCATGCTGGCGCAGGCCGCGGCGCACGGCGCTTACCACGCGGCCGTCGCAGCCGCGGCCAAGGGGAAGAATATGTCATCCCTCTACCCGTTTGGCATGCCAGGCTCGGAGAAGGATCGGCATTCGGGCATAGACTCGCTCACCGGCCTCCCCCACACTATACTCAGtgCTGCTTTGGAAGGAGGtgaTCCGTCGTCAGTCCTGGGCGGTGTCCGATTGCCGCCAGACACAGAGATCATCAAGTACACCTCCTCGCTGGCGGGGCCCAAGGCACCTCCCGGCACCACGAATAGAGGGAGAAAAAAAACGATATCGTTAGACCCACCCCAAGTGTCGGTGCATCCTTCTTCAGGCGATAGGGCCACGCCGGTACCCAGCAAAAGGCAGAAAATGGACGAGTACGGCAACTCGCGGTCGTCGGTGGAGGTGATCCGGCTGCCGACTAAACCGGACCGGCCCGGATCGCACTCCGGAACGCCGCCGCCCAACCTGTCCGACTATGCTGGTATATCTCGCGAGCTGCTCCAAACCATCGCTAGTCAGAGCGGCGTCAGCCTCGCGGCGTTGGAGAGGCAACTCGCGGGCACCGCTAATAACACGGaTTCAGGTCTAAACCTAAGCACCAAATCTAGCGACGACACGCCCCTAGATCTGGGAGTGAAGCAATGTTCTATGGACGACGATGCTCCACTCAATCTGTCGCTGAAACCTACGCCTTCGAGCCACCAAGCTTCGGACGCCCTCTCGCGGTTAACGTCGCTAAGTAGTTCATTGAATGCTTCCGGCGGAAACGATAGGATATCTCGCCGCAAGCCGGGCGCCAAGCCGCGGCGGGTGGCGCCGGAGCTCAACACGCAGGTCGCGGACTCGCCGCGGCCCAAGTCCAGCGGCAGCGAGGACAGCGAGTCTATCTCCACGTGGCCCACCCGTGAAGGCCGGCCTCGCAACCTAGGCCGAGGTGTGAGCAAGCCAAAGAAGAACACTGTGGCCTCGCTGCTGGCCCAGAGCAGAGCCCTAGGCCTCCGCCCCGCGCTGGCGCAGCAGCTGCTGGGAGAGACTGACTTGGAGAAGCTAAAAGCACTGCTCGGCGAGAGTGCGAGCACAGACTCCGAGTGTGTGTCGGACAGTTGTCCGTCGGACTCGGACGCGTCCGACACATCGCGAAGATCTAATGACGCGCAACTAAGGCTACCTTTAGCTTTGGGTTGGAAACGAGTGACTGTGATAAGGGGCCTCTCGCGTAACTGCAACATCAAAGGCGACGTGAGCTACTCCCCGCCCGAGCCGCACGCGGCGATAGCTATCAAGACTGTACACGAATTACATGCGTTCATGGAATCAAACCCGAACCCTCCGTTATCGAGCGACAACTTCAGCTTCAGCGCTAGAGTGGTGCTAGGCGAGTACGTGCAGCCCGCCGAGTTAGGGGAGCCCTTAGTGTTCAACGAGCAGGAGATCACTAAACGTTTGGAAGAAGCCCGCGCCCTAGCGGCCCTGACCGGCCCTCGGCCCACGCCCCCGCCCGTCGACCGCCGCATAGAGCTCGCTAGAAGGCAACAAGCTGCTAGAGACGCGAGAAGGGACGCCAACGCGAGGTCGAGAGATCAGGCTCGCCTAGTCAGAGAGCTAGAAAGAACGGAAAAGGCCGAATCAGTGAAGCGGGATAAAGAGGCGAGATCCCAACAACTACTAGAGCATATCAACAAGAACCGAACGCAGCTCACCATCGAGCCGCTGCCTTCGATTCCGAAATCTGGTACGGATAACGAATGGAAGATACCAGAAATAGTGATGGGCCCCGCGATAAAAACCAGTAAAGACCGAACAATGCCACCCATAAGTCTCTCACTGATACCAGTTTCTGGGAAAGATTCCCACAATGCCCCTATAAAAACAATCAACTTCGATACCAACTGGAAAGAGGATGAATATAACGCTTTAGATAAAATGAAAGATTTTGCCGAAAAAGCTGCTTTCGACCTCCCCAAAAGGCCCAAAGACAAATATTTCGATATCTCCCTGATGAAGGCACACGAAAAGCGATTTAAATCCACAGACAAAGATAATAATTTGGAAAAGCTAATAGAATCGTACTCCCGTATAACGGAGTTTATAAACGGTTGCAATTGGTCGCAACTACCCGCGAAAAAGTCTGAGGACGCTATAGCGATTGAGCAGAAATAtttggatgccaaaaacgagTTTATGTCGCAAAACTTAGCGTTGATGCCGAAAGATGGGCAGAAATCGGTGCTAAAGGAAGTTATAGACTTAAGTGAGGATGATGAAATAATACTCAGtgatataataactaaaaagataagTGAAGGGACGTTCAATATCGGCAAAGATGGCGCGCTATCTATATCGGTACATCAACTCGGCAATAAGGATGCCTTAGGACTGGCTAAGAGAAAAAAACATGAGGAAATTGAGAAGCAGAAGATCGAAGATCAGGTGAAGAGGCAACAGGAAAGAGAACTTAAAAGACAACAAGCTATGCTTCTCAAAGAACagCAAAAGTATATCACTGAGGAGCGCGAAAGGAGGCGGCAACACACTACATTTATCCGACAACTGGACTCAAGAAAGAGATGGGAGGAGAGGGAACGGAGAAAGCACCAGAACCTTCTAGACCGGCTGCTGGTGAAAGAGAAAAAGCTGCAGCAGAGAAGGAAAGAGATGGAGCTACTGGCTGAACTTAGACGGCCGCAAGAAGACTCCTCGCTCTCCGACCAGAAGCCACTCCCCACTTTGAACCGGATCCCGGGGCTAAAACTGCCCGGGCAAGCGTTCGCAAACATACTACAAGTGTACGAGTTCATACACAACTTCGGACAGACTTTAGGATTCGATATGGACAACATTCCGTCTCTGAACACGTTCCAAATGGCTTTACTACCCGACTGCTGTGCGGACGCAGAGGATGAGCTTATTCAAGTGCTGACACAGCTGCTAGTTTGTGCTATTGAGGATCCCGGAATCCCGCACCCGGGACGCCATACAACTCTACTAGGCCACGCGATTCGTATGGGAGACATTACACCCTCCAACTTGAGCGAAGTGTTACGGATATACCTGTACGCTAACGCGACGGGCGAAGTCAAGGCTCTAACAGGTTTAACAGCGGAGAGAGAAAGAGAGCGGCGCGTGGCCGACCACCACCAGACGGAGGCAGAAATGCAGCACACGTGCGCTAGTACCAAGAACGCCAACTATTACGAACATCTGCATAGCAACAACACGTATAAACTCTCAGAAGCCCTACGAGATAAGCCGTTCCTAGCCCTAAACCCGACACACAAGGCCAAGATACTATCGTTCTTGTGCGACGAGCTGCTACAGAACAAATCGGTGCTGCGACAGATCGACGGCTCACTCGAACACCTCAACCAACTCAAGAAGGAACGATATCTACTCGATATGAAGATCAGAAAAGTCCGCGTCCTCCACCAGCGGAAACTCCGCACGGAACAGGCGGAGAAGCAGCAAGCGCTCGCCCTCGAGCGGATGCAGCGGTTGGTCGAAGAGAGCACGGCCAATCTGAACCGAGCCTCGCCGCTACCGCACGACGAAGAACAACCAACAGACAAAGAAACCCCCAAAAAAGACTCATCAACGCAAGAATCAGAAGAAAAACCGTCATCACCGTACAAAGAAGCTCCCCCCGAAGATAGCGACAAGGAATTGTCGCCCTTAAAGGATCTCTCCAACATGAACAAAAGCAAAGAAGCGCTGAATAACAATAAGGAGGATTGTTCTCCAGCAGACAACTCGAAGTTGGATAAAGATAGTGTGATTGGGGATTGCGATGCGAATCTTAGTGATTTGGAGAGTGAAGGCACGCAGCCTGAAGAggaCGAAGACAAAAACCTCTCATCCGAAGAGTTGTCCCGCAAACTAGACAAACTGATGCGTCAGTCGGAACAGCAATCACAACAGTTGGCCTCAGGGACTCACGCGCTTAGAGCAACTTGTTATGGACAAGACAGGTATTGGCGTCGATACTGGTCGCTGGGCAAATGTGGCGGCATTTTCGTGGAAGGTATGGAGTCTGCGCAGCCCGAGATCATGGACTACCAACATACTTTAGAAACTAACGCTAAGGATAAACCCGCGGAGAATACTAAGAAGAAAAAAGGCGCCAAAGAAAAGAAAGACTCCCAACTAGAACCAGAGAGCATGGACACCGAAGAGGCTATGAAGGTGGAAGCTCTAAAGACTGAGATGGAGCTGAAGAGCATCAAGTCGGAGCTCAACTTGAGCGATCACACGCAGATCATTAAGTACGAGCCGAATGTCAAACATGGCGCGTGTAAGGTTGAAGGTTCATCAATAAAAATGGAAGAGAAATACATACAACAGCAGCAACATAACGAAGCACAAGACATGCTAGATATAGAAGACTCCATCCCCACCGCATTCCTAGTACAAAAGCCTTCGCACAAACCAATGTACGCGTCACAAGCCGAACCCGTCGACAAACCACAAGAGATAGTCAAAGTAGAAAACgttgttaaaaaagaagagaGAGAAGAAGAAGAGAGTAAAGacgaattaattaataacttagAAGAATTAAGGAAACTAGCAGAAGCAGTTTCTTCTCAATTAGACGCGGCTAAGAAAGCAGAAGCCGAGATTAAAGTAGAAGAAAAGGAACCGCTAGAAGTAAAGAAAGAAGTAATGGAACCTACCGCCGCCCATAGTCATTTATACACGAAAATTTTAGAAGGCAAATGGTTCTCTATTTTAAGGCATGAAAGTGCATTTTTGAATAACATAAACGAGGTTGTGGATAAGACTGATGTGCCGAATTATTGTGATAACGAACATACTTGTGCTGAAGTGATATTGTGTCAGGGTCATAAGTGGGATGTGTCTAATAACTTGCATTTGTTGAACGACCCTAGTTTGTTCACTCTTAACTCTATGGTGACCAGTGTTCAGGTGCCGTCGAATAGTGTTTATGCGGACTCTAGCTTGACTATGTCTGGATTAGATCAGGATATGATCAACGCTAGTTTGAATAGAAATGACAAGGAAGAGGAGGAAGTTGAAAATGGCGTTAAAGAACAGGACAACGATTTAGAAAAGGAGTTACAAGCGGACGCCCTAAAGCACGACCTAGCAGTACAAAAGGCTAAAGCCAACAGTCTAATAAGCCTCGGTTTACTGAACTTCAACGCGTTATCTACGTACGTGACGTGTGACAGTCCGCCGCCGATACAAATGACGGTAGAAGAAGTGAAACAACTAGAtcaatgtaaacaatatggacTGCCGAAAAGATTAGAAGGGACTTTTGTACCGAGAGAACTTAGGCACGGCTGGTGGCGTATAACAGAATCGGATCAGCTGCGAGATTTGCTGGAAACTTTACACCCGCGCGGAGTGAGAGAGAGGGAACTACACACGGCGTTTGTGCAACATGTACCTACTGTTAATAATAAGATCTACATCGAGCGCGGCGACGTCAACATGACTGAGCTCTCTGTCACGCACATGGACCGCGTGATAGCGCAGAGCGGTGGTTTCCCAAGCCCCGATTTCGCAGAATCGTTTTGCGCCACTACTGCTAATAGGATAGACGAGCAAATGTTGAAGGCTGTTAAACAACTAGAACAGCGAGTGATCGCAGCGTCGTTGCAGACCAAAGGTTGGCGGCGAGCGGTGTCACCGGAACTAGATGACGTCACCGACATAGTGGCTGTAGCGAGGCAGCGATTGGCCGCCGTCGAAGCGCATATAGAGAGGCGATATCTAAAGCCGCCTCTGGCGCAAAGGTACGCTAGTAACGCGGAAGCGACGCTGGGCGCAGTTTTACAAGGCGAACACGGAAACTCATCTGCACCTTCGCCGCAGAACTCCAACGCTAACGAGGGAAAAGGTAAGATATATATCCAGCGATGA
Protein Sequence
MSCLLIALTRNTYEQFPLAGRKPSSQSSSSKGKERDLALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSSLYPFGMPGSEKDRHSGIDSLTGLPHTILSAALEGGDPSSVLGGVRLPPDTEIIKYTSSLAGPKAPPGTTNRGRKKTISLDPPQVSVHPSSGDRATPVPSKRQKMDEYGNSRSSVEVIRLPTKPDRPGSHSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGTANNTDSGLNLSTKSSDDTPLDLGVKQCSMDDDAPLNLSLKPTPSSHQASDALSRLTSLSSSLNASGGNDRISRRKPGAKPRRVAPELNTQVADSPRPKSSGSEDSESISTWPTREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAQQLLGETDLEKLKALLGESASTDSECVSDSCPSDSDASDTSRRSNDAQLRLPLALGWKRVTVIRGLSRNCNIKGDVSYSPPEPHAAIAIKTVHELHAFMESNPNPPLSSDNFSFSARVVLGEYVQPAELGEPLVFNEQEITKRLEEARALAALTGPRPTPPPVDRRIELARRQQAARDARRDANARSRDQARLVRELERTEKAESVKRDKEARSQQLLEHINKNRTQLTIEPLPSIPKSGTDNEWKIPEIVMGPAIKTSKDRTMPPISLSLIPVSGKDSHNAPIKTINFDTNWKEDEYNALDKMKDFAEKAAFDLPKRPKDKYFDISLMKAHEKRFKSTDKDNNLEKLIESYSRITEFINGCNWSQLPAKKSEDAIAIEQKYLDAKNEFMSQNLALMPKDGQKSVLKEVIDLSEDDEIILSDIITKKISEGTFNIGKDGALSISVHQLGNKDALGLAKRKKHEEIEKQKIEDQVKRQQERELKRQQAMLLKEQQKYITEERERRRQHTTFIRQLDSRKRWEERERRKHQNLLDRLLVKEKKLQQRRKEMELLAELRRPQEDSSLSDQKPLPTLNRIPGLKLPGQAFANILQVYEFIHNFGQTLGFDMDNIPSLNTFQMALLPDCCADAEDELIQVLTQLLVCAIEDPGIPHPGRHTTLLGHAIRMGDITPSNLSEVLRIYLYANATGEVKALTGLTAERERERRVADHHQTEAEMQHTCASTKNANYYEHLHSNNTYKLSEALRDKPFLALNPTHKAKILSFLCDELLQNKSVLRQIDGSLEHLNQLKKERYLLDMKIRKVRVLHQRKLRTEQAEKQQALALERMQRLVEESTANLNRASPLPHDEEQPTDKETPKKDSSTQESEEKPSSPYKEAPPEDSDKELSPLKDLSNMNKSKEALNNNKEDCSPADNSKLDKDSVIGDCDANLSDLESEGTQPEEDEDKNLSSEELSRKLDKLMRQSEQQSQQLASGTHALRATCYGQDRYWRRYWSLGKCGGIFVEGMESAQPEIMDYQHTLETNAKDKPAENTKKKKGAKEKKDSQLEPESMDTEEAMKVEALKTEMELKSIKSELNLSDHTQIIKYEPNVKHGACKVEGSSIKMEEKYIQQQQHNEAQDMLDIEDSIPTAFLVQKPSHKPMYASQAEPVDKPQEIVKVENVVKKEEREEEESKDELINNLEELRKLAEAVSSQLDAAKKAEAEIKVEEKEPLEVKKEVMEPTAAHSHLYTKILEGKWFSILRHESAFLNNINEVVDKTDVPNYCDNEHTCAEVILCQGHKWDVSNNLHLLNDPSLFTLNSMVTSVQVPSNSVYADSSLTMSGLDQDMINASLNRNDKEEEEVENGVKEQDNDLEKELQADALKHDLAVQKAKANSLISLGLLNFNALSTYVTCDSPPPIQMTVEEVKQLDQCKQYGLPKRLEGTFVPRELRHGWWRITESDQLRDLLETLHPRGVRERELHTAFVQHVPTVNNKIYIERGDVNMTELSVTHMDRVIAQSGGFPSPDFAESFCATTANRIDEQMLKAVKQLEQRVIAASLQTKGWRRAVSPELDDVTDIVAVARQRLAAVEAHIERRYLKPPLAQRYASNAEATLGAVLQGEHGNSSAPSPQNSNANEGKGKIYIQR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00347491;
90% Identity
-
80% Identity
-