Basic Information

Insect: Agriphila geniculea
Gene Symbol: ibtk
Assembly: GCA_943789515.1
Location: CALSUL010000095.1:2092455-2120828[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 5.8e-13 4.8e-10 41.4 0.0 8 79 1107 1176 1100 1184 0.90

2 3 1.7e-10 1.4e-07 33.4 0.0 9 106 1296 1397 1290 1401 0.84

3 3 2.1 1.7e+03 1.0 0.2 79 107 1402 1430 1396 1433 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	5.8e-13	4.8e-10	41.4	0.0	8	79	1107	1176	1100	1184	0.90
2	3	1.7e-10	1.4e-07	33.4	0.0	9	106	1296	1397	1290	1401	0.84
3	3	2.1	1.7e+03	1.0	0.2	79	107	1402	1430	1396	1433	0.88

Sequence Information

Coding Sequence: ATGCACACCGTTGGATTGCCCCGAACCTGTTTAGGTTTCACGAACATTCTGTTCTTTATGTTTGGATTAATTGGTTTCGTAATTTGCGCGTGGTGTGCGTTCAACACACAGTTCTTTCAAGACGTCAATTATACAGTCACCAATAGTCCAAAAGTTGGAGATATCGCCGAATTCGTTAACCTGAAATTGTGGTACATTCCTATGACGACGATACTAATAAGTATGGCGGTTTTGACTATGCTGACCTCTTGTTGTGGAATTCTAGCGGCTGGATGCCAACTGAGATGCGCCGTTAAATCGTACATATTCCTTGTTACCCTCATCTCTTCAGTGGCATTTTGGGTGTTCTTCATATCTGGAATACACAACATATACACTAAAAACGAGAAGACACGAAAGTATTTCGAAAGAACGATACATTCCGATTACGGAATGGAAAACGACTTGATAACTTATTTCTGGAATTACGTTATGATGGAATACAAATGTTGCGGCACGAATAGTTACAAAGATTTTGCGGACTCGAATTGGCAGAAGAAAACTAAGAAACTGTATCCCGTGCAATGTTGCAAGTTGGCGAACAAAACCGCGCTCATACCCGTTTCAAAGGACTGCACTTTGATTGTTGATAAATCGATCGAATCTTTTATAGATACCGGTTGTTTCGACGTCCTGAGTGAATCTATAGCGTCGAATAAGGGGAAGTTGATATTTTACGTGATTCTGTTGATAATAGCGTACTCAGTATTGATTTTGTTCGCATATTGCATTTTTAGAGGAGAGCCTCTGATAAGGGCTTTAACTGGAGGATATGAGTATCCGTCGACTGTTCAAAGTCATCCTAGTGAAGCGGTGCCTGCCAGGTCGTATACTGAGAATATTTCATATGTAGAGGAACCTACGAAGAAAGTTGTAAGAGTGATTTCCGCTGTCAACCCATTTCAAACTTACAAGTTTACGCCGAATACCATGCCTTACAGTGATGATGGATATCATTATCCAACGATTAAGTGGTACGAAATAAGGATTCTGATCCTTCATTCGATCATAGCAGAAACGAGATTTCTCTGTGAGAATAGTTGGAGGCGACTGATGACGAAGGTGCGCGAGCTACGCAGCGTCAGAGTGTGCTTAGGCAAATTCCACAGCGTATACGTATGCTCGGGCGCGTCGCACGGCGAAGTATGGTGTTGCGGACAAGTGTCCCGGGCGGGCGGGCCGCGCGCTACTTGCCTCGCGCCCGCACTACTGGCGCTGTGGGAGCCGTGCGTGCAGGCTGCGGTGATGCTGCACGCGACCGTGCTGCTGCTGGAGAGCGGCGCGGTGAGTATTAGCCGGGGTACATGTAGCGGGCGAGTGCCCCGCGCGAGCGGGCCGCGCGCTACTTGCCTCGCGCCCGCACTACTGGCGCTGTGGGAGCCGTGCGTGCAGGCTGCGGTGATGCTGCACGCGACCGTGCTGCTGCTGGAGAGCGGCGCGGTGAGTATTAGCCGGGGTACATGTAGCGGGCGAGTGCCCCGCGCGAGCGGGCCGCGCGCTACTTGCCTCGCGCCCGCACTACTGGCGCTGTGGGAGCCGTGCGTGCAGGCTGCGGTGATGCTGCACGCGACCGTGCTGCTGCTGGAGAGCGGCGCGGTGAGTACTAGCCGGGGTACATGTAGCGGGCGAGTGCCCCGCGCGGGCGGGCCGCGCGCTACTTGCCTCGCGCCCGCACTACTGGCGCTGTGGGAGCCGTGCGTGCAGGCTGCGGTGATGCTGCACGCGACCGTGCTGCTGCTGGAGAGCGGCGCGGTGAGTATTAGCCGGGGTACATGTAGCGGGCGAGTGCCCCGCGCGAGCGGGCCGCGCGCTACTTGCCTCGCGCCCGCACTACTGGCGCTGTGGGAGCCGTGCGTGCAGGCTGCGGTGATGCTGCACGCGACCGTGCTGCTGCTGGAGAGCGGCGCGGTGAGTACTAGCCGGGGTACATGTAGCGGGCGAGTGCCCCGCGCGGGCGGGCCGCGCGCTACTTGCCTCGCGCCCGCACTACTGGCGCTGTGGGAGCCGTGCGTGCAGGCTGCGGTGATGCTGCACGCGACCGTGCTGCTGCTGGAGAGCGGCGCGGTGAGTATTAGCCGGGGTACATGTAGCGGGCGAGTGCCCCGCGCGAGCGGGCCGCGCGCTACTTGCCTCGCGCCCGCACTACTGGCGCTGTGGGAGCCGTGCGTGCAGGCTGCGGTGATGCTGCACGCGACCGTGCTGCTGCTGGAGAGCGGCGCGGTGAGTACTAGCCGGGGTACATGTAGCGGGCGAGTGCCCCGCGCGGGCGGGCCGCGCGCTACTTGCCTCGCGCCCGCACTACTGGCGCTGTGGGAGCCGTGCGTGCAGGCTGCGGTGATGCTGCACGCGACCGTGCTGCTGCTGGAGAGCGGCGCGGTTGTTCAATACTCGCTAAACAGCACCGACAACGTGAGCCAATCTGGCGTTAAAACCCCAACATCCATCAAGCTGCCTGCAATCAAACCACTGCTAAAGTTGTCGCAGCCTATCGGCGTGTGCGCAGGGAGGTCGCACGCGGTCGTGTGGAACATACGCGCAGTGTATACGTGGGGGACCAATGTTGGACAATTGGGGCATCCGCATGAAGAAAAAGTAGTTGCCGCACCAAAACGAGTAGCAATATCTATAAACAACAAGGAAGACGCAGGTTTTCAGCTAGCGGGCGCCGCAGACGCCGCCACCGTCCTCACCACGAGCCGCGGCGACGTGTACTTACTGCACAAGTACATGTGCAAGAAGATCGCCATCAAGCAAATTAACCTTCGCCAAGTGTGCGTGGAGGCTAAAGTGAGCGAGCAGGGTGTGTATTCAAGAGTGACAGTACTACTGCTGACCACTGTTGGGCAACTGCTCATATGGCAAGACACCACCAACCAACTTACCAGATGCGTCTTCGGCCTAAGCCACCAAACCGTGATAACTCAAGTGACGTTAACCCACGACGCTCTCTACTTCACGACTAAACACGGCGAAGCGTTCATTGGCAGTATATCTAGAAAGACCACGCCCACTCAGCCGCAGCCAATCAAAAGGGAGAAGGAAAGAGACAACAACAAGTCGGCCCTAGTGAAGTTTTTGGAGAAGGATGATTGTACTCCGGTCAGGATCACGAAAATACCGAATGTTCATAGAGCAGTGTCGATTGCAGTGGACAGTGAAGGTCTTAACTTCGCTTGCTTACAAATAAAGCCGACATGCGGACTGCGATCTCTGCCGGAATTATCGCCATCAGGATTAGCCAAGCACATGGAGTCACTTATGGAATCGGCCGCTGACGGCGACCTACTGCACGATGTTATATTCAAGGTGGGCCCCAAACTATTCCCAGCGCACATATTCATAGTAGCATCCAACAGTGATTTCCTCTACAAGCTCTACCAAGACCTCAAACTCCCTGGAGACAAACCTACAATAAATCTAGACCATATACACCCAGACGTGTTCCAAAGGATACTGAAGTTCGCGTATACTGGAACGTGTGACGTGGCGGAATTAGGCCCCTGCAGTTTGAAGATAAGGAAGGAAGATCTGCCGGTGGTGAAGAAAGGGAAGGAGAATGTTGAGGAAGATACGGAGCTCATTGAAAACTCATCAGAAATATCAGCGTACGATGTGTACAAACAAGACAAGCAGAAGCGTAAAGGTCGTCGCAGCACCGAAACGCCGCCGAAGCACACGCACTGCGACCCCGTGAAGTTGGTGCAGGCGGCGGCCAAGCGACTGCAAGTGATGTCACTGCACAAACTACTCGACAAATTCTACTACCGAGATGGTACTATTTATCTCAAGGAATCTGCTACCTACTCCAAAAACTTGCCCCAATATTGGCAGCGAGATTCCTTGCCCGAGCTAGTGGACACCAACGTGTGTTCCAAAGACGGGATTCTGGTGCCCGCGCATAAGTGCGTGCTAGCCGCTAGATTGGACTATTTTCAGGGCATGTTCCTGCATTCTTGGACTGAGAATAAACTTCTTTCAAAAGTCAATCTACCGATAAACCATGGGATTCTTCTACCGGTCATAAACTTTTTATACACCGACACATGCCCTGAAATTGAAACTTCAGACAGCATTGACTTCATATGCAGCATGCTCATAGTCGCAGATCAGCTGTTCATAACGCGTCTACGAGAAATGTGTGAAGTCACTCTAGCAAATCTGATCACGCTCAAAAACTGCGCAGAACTTTGCCAATTCGCCCACACGTACAACGCTACCCAGCTCAAACAATGCTGCATGGAATTCATATCCCTAAATCTGTCCAGCGTCCTTGAAAACAAGTCTTTAGATGTCATTGAAGAAGTTTTACTTGACGACATTTCTAAATACTACTGCAAATTCAACCCTATTATGTCATCGAGAGTGATAACACCATTTTACTGCGCCCCCAGTGATGAAATGATTGAAGAATGCGCCCTAAACTATCCTGTCAATTTAGATTACACCGATGAAGAAATGAAAAAAGATGAAGCATTCTTAGAgctgaataaaaagaaaagtaaatcTAAAAAGATTGAGTACACGGAAAGTGAGAAAGCCAGGATGAGATACGAATCTGTTAGCTCAGTGACGTCACTAGACTTGTCGAATGAAATTTCCGGAGACATCACTTTGTCACTCAGCAATATATCTAAAGAATCTGAGAAAGGTATtcgtgaaaaaaaagaaaagtggATAGAAGTACCGTCTGCTTTACAAAAGCAGCAAAAGGTTATCCAAGCTAGATTGAAAGCTGTGAGCAGCGCTAAAGACATTCTGAATGagcctcaaactgaacaattcacAAGGTTGACTAAGAATAACTCATTTAGCTCTATTCCTCGAAGTCAAGAGAAAAATCCGACTACTTCACGAATGTCTGTCTCTCCGAAGGAATCTCCTCTTGCAGATTTGGCTAGAAGTCCTCAAGGCAATCTGGTCATAAGTCATGTAGGACCAAAACTGTCCCAAAAGCAAAGAAAGAAAATGGCTACGCTTGGTGAAAATACTTCACAAAACCTAAATGATTACTCTGCTAATAAGTTAATCATAGAAAGTCCCTCAGAAAAGCCTAAGAATCCGTGGAAGATTTGCGAGCCCCCCATCGCCAGTAGCAGTCCTAAAGCAAAAACTATTCAATTTAATCAAATATTAACAGATCAAAGGAAACAGAAGGAAGACCTTTCAAGAATCATGACAAAACCTCTCGCATTGACACAGCTTGAAGATAAAGCCATAGAAGAGTTGGAGAGATTCTACAATATCCATGAAATAGACGATGAGCTTATCACAGTTAGACGCATCGAGCTTCAAGTGTCCCCGCCACAGTGGGTCCACACCACCCCAAAGTGA
Protein Sequence: MHTVGLPRTCLGFTNILFFMFGLIGFVICAWCAFNTQFFQDVNYTVTNSPKVGDIAEFVNLKLWYIPMTTILISMAVLTMLTSCCGILAAGCQLRCAVKSYIFLVTLISSVAFWVFFISGIHNIYTKNEKTRKYFERTIHSDYGMENDLITYFWNYVMMEYKCCGTNSYKDFADSNWQKKTKKLYPVQCCKLANKTALIPVSKDCTLIVDKSIESFIDTGCFDVLSESIASNKGKLIFYVILLIIAYSVLILFAYCIFRGEPLIRALTGGYEYPSTVQSHPSEAVPARSYTENISYVEEPTKKVVRVISAVNPFQTYKFTPNTMPYSDDGYHYPTIKWYEIRILILHSIIAETRFLCENSWRRLMTKVRELRSVRVCLGKFHSVYVCSGASHGEVWCCGQVSRAGGPRATCLAPALLALWEPCVQAAVMLHATVLLLESGAVSISRGTCSGRVPRASGPRATCLAPALLALWEPCVQAAVMLHATVLLLESGAVSISRGTCSGRVPRASGPRATCLAPALLALWEPCVQAAVMLHATVLLLESGAVSTSRGTCSGRVPRAGGPRATCLAPALLALWEPCVQAAVMLHATVLLLESGAVSISRGTCSGRVPRASGPRATCLAPALLALWEPCVQAAVMLHATVLLLESGAVSTSRGTCSGRVPRAGGPRATCLAPALLALWEPCVQAAVMLHATVLLLESGAVSISRGTCSGRVPRASGPRATCLAPALLALWEPCVQAAVMLHATVLLLESGAVSTSRGTCSGRVPRAGGPRATCLAPALLALWEPCVQAAVMLHATVLLLESGAVVQYSLNSTDNVSQSGVKTPTSIKLPAIKPLLKLSQPIGVCAGRSHAVVWNIRAVYTWGTNVGQLGHPHEEKVVAAPKRVAISINNKEDAGFQLAGAADAATVLTTSRGDVYLLHKYMCKKIAIKQINLRQVCVEAKVSEQGVYSRVTVLLLTTVGQLLIWQDTTNQLTRCVFGLSHQTVITQVTLTHDALYFTTKHGEAFIGSISRKTTPTQPQPIKREKERDNNKSALVKFLEKDDCTPVRITKIPNVHRAVSIAVDSEGLNFACLQIKPTCGLRSLPELSPSGLAKHMESLMESAADGDLLHDVIFKVGPKLFPAHIFIVASNSDFLYKLYQDLKLPGDKPTINLDHIHPDVFQRILKFAYTGTCDVAELGPCSLKIRKEDLPVVKKGKENVEEDTELIENSSEISAYDVYKQDKQKRKGRRSTETPPKHTHCDPVKLVQAAAKRLQVMSLHKLLDKFYYRDGTIYLKESATYSKNLPQYWQRDSLPELVDTNVCSKDGILVPAHKCVLAARLDYFQGMFLHSWTENKLLSKVNLPINHGILLPVINFLYTDTCPEIETSDSIDFICSMLIVADQLFITRLREMCEVTLANLITLKNCAELCQFAHTYNATQLKQCCMEFISLNLSSVLENKSLDVIEEVLLDDISKYYCKFNPIMSSRVITPFYCAPSDEMIEECALNYPVNLDYTDEEMKKDEAFLELNKKKSKSKKIEYTESEKARMRYESVSSVTSLDLSNEISGDITLSLSNISKESEKGIREKKEKWIEVPSALQKQQKVIQARLKAVSSAKDILNEPQTEQFTRLTKNNSFSSIPRSQEKNPTTSRMSVSPKESPLADLARSPQGNLVISHVGPKLSQKQRKKMATLGENTSQNLNDYSANKLIIESPSEKPKNPWKICEPPIASSSPKAKTIQFNQILTDQRKQKEDLSRIMTKPLALTQLEDKAIEELERFYNIHEIDDELITVRRIELQVSPPQWVHTTPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -