Basic Information

Insect: Agrilus mali
Gene Symbol: Znf423
Assembly: GCA_029378335.1
Location: CM055664.1:1364103-1377071[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 3.1e-06 0.00031 22.0 0.9 1 23 127 149 127 149 0.98

2 21 1.3 1.3e+02 4.3 3.7 1 23 155 177 155 177 0.94

3 21 1.4e-06 0.00013 23.2 3.6 1 23 183 205 183 205 0.99

4 21 0.00022 0.022 16.2 0.6 1 23 211 233 211 233 0.98

5 21 0.013 1.2 10.7 3.1 1 23 250 272 250 273 0.93

6 21 0.28 27 6.5 0.4 3 23 290 311 289 311 0.95

7 21 2.1 2e+02 3.7 2.0 1 23 343 366 343 366 0.96

8 21 0.0051 0.5 11.9 0.2 1 23 456 478 456 478 0.97

9 21 0.0016 0.16 13.5 0.1 2 23 492 513 491 513 0.96

10 21 0.058 5.6 8.6 1.6 3 22 523 543 521 545 0.76

11 21 0.052 5.1 8.8 0.4 1 23 550 573 550 573 0.97

12 21 2.3 2.2e+02 3.6 0.9 1 23 580 603 580 603 0.95

13 21 0.14 14 7.4 7.2 1 23 640 663 640 663 0.96

14 21 0.015 1.5 10.4 1.7 1 23 714 737 714 737 0.98

15 21 0.14 14 7.4 4.4 2 23 749 770 748 770 0.96

16 21 0.026 2.5 9.7 0.6 1 23 779 801 779 801 0.96

17 21 0.65 64 5.3 2.7 2 23 809 830 809 830 0.96

18 21 0.024 2.3 9.8 2.6 2 23 937 958 936 958 0.96

19 21 0.052 5.1 8.8 0.5 1 23 967 989 967 989 0.96

20 21 4e-05 0.0039 18.6 0.6 1 23 997 1019 997 1019 0.98

21 21 0.07 6.9 8.4 1.6 1 23 1026 1048 1026 1048 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	3.1e-06	0.00031	22.0	0.9	1	23	127	149	127	149	0.98
2	21	1.3	1.3e+02	4.3	3.7	1	23	155	177	155	177	0.94
3	21	1.4e-06	0.00013	23.2	3.6	1	23	183	205	183	205	0.99
4	21	0.00022	0.022	16.2	0.6	1	23	211	233	211	233	0.98
5	21	0.013	1.2	10.7	3.1	1	23	250	272	250	273	0.93
6	21	0.28	27	6.5	0.4	3	23	290	311	289	311	0.95
7	21	2.1	2e+02	3.7	2.0	1	23	343	366	343	366	0.96
8	21	0.0051	0.5	11.9	0.2	1	23	456	478	456	478	0.97
9	21	0.0016	0.16	13.5	0.1	2	23	492	513	491	513	0.96
10	21	0.058	5.6	8.6	1.6	3	22	523	543	521	545	0.76
11	21	0.052	5.1	8.8	0.4	1	23	550	573	550	573	0.97
12	21	2.3	2.2e+02	3.6	0.9	1	23	580	603	580	603	0.95
13	21	0.14	14	7.4	7.2	1	23	640	663	640	663	0.96
14	21	0.015	1.5	10.4	1.7	1	23	714	737	714	737	0.98
15	21	0.14	14	7.4	4.4	2	23	749	770	748	770	0.96
16	21	0.026	2.5	9.7	0.6	1	23	779	801	779	801	0.96
17	21	0.65	64	5.3	2.7	2	23	809	830	809	830	0.96
18	21	0.024	2.3	9.8	2.6	2	23	937	958	936	958	0.96
19	21	0.052	5.1	8.8	0.5	1	23	967	989	967	989	0.96
20	21	4e-05	0.0039	18.6	0.6	1	23	997	1019	997	1019	0.98
21	21	0.07	6.9	8.4	1.6	1	23	1026	1048	1026	1048	0.94

Sequence Information

Coding Sequence: ATGTCCAGACGAAAACAACCTAACCCTGCCAAACTAGAAGAAACTGAAATTCCCAACACCGACCATACGTACAAAACAAATTCTAACACGGCACAATCTCAAGTCAAAGAAGAGGAAGAGGCTGATGGTAACTTTCAAAGAAATAACTTCGAATCTTCCACTGACAATAACGACGAAAATTACGTCAAGGTAGAACCATTTGACCAAGAGGACCATGAAGACAGTCTAGGATCGGTTGGAACAAACCAGGCGAGTTGGGATTCGAATACACCAGAGCAAGCATCCCCAGCGTCCAGTTCCTGTCCCACCCCCAGCTCAATTGTAAGCGATGTTACAGACGCGGAAGTTTTTACGGTGGGTGTTACAGAAACTACCCCGTACGCGTGTAAAATATGCAACAAAGCGTTCGCAAAAACTTCACAACTCACCCGCCACGAACAGactCACTCCGATCATTTACAGTATAATTGCATTTACTGCCCTCGTTTATTCAAACATAAAAGGTCAAGGGATAGGCACATTAAACTCCATACGGgagataaaaaatacaaatgctCCTTTTGTGATACCGCGTTTTCAAGAAGcGATCACTTAAAGATCCATTTGAAAACCCACGACAATAGTAAACCGTTCAAATGTTTCCTGTGCAATCGGGGGTATAACACAGCAGCAGCCCTAACGTCCCACCAACAGAGCCATATTAAACAGGATAAAGATAATAAGGACCATAATAATAGTTCAGAAAGTCATGCATGCTCGTACTGTTCAGAAACGTTTCAGAAACTAGAACTTCTACAGGCTCATACGTCTTCACACCACCTTGAGCCTTTAACAGAAGAAGGAAACGGGGATGGTACGAAGTGGTTGTGTATGTACTGTACTAAAGATTTTTTATCGCTCGACGAATTACAGCAGCACGTAAATAATTCGCACGATGTTGTAACAGATTCAAAAAGCGACGATTCGTCCTGTAAATCTTCGATAAATAATTCGTCTCAAATTATTAATCAAGTCCAGCGCGTCTCGTATCCCTGTTACAACTGCACAATGCAATTTTATTGCCTTGAAAAATTAAGGGACCACATGGCTAGAGTTCACTGGGGAGCGACGACACAACAGAAACTCCTCTCCAATGCCGTTTTAAAAGATTGCAATATTTGTCTTCCTATATCCCAGAATTGCAGTGCACCCCCGCCCTCTCTGACACAAACCTCCACCGATCATTCCATTCAGTTATTGCCCACGGATCTAAGTTGGAAACGCAAAGCAGAATTGTCCGACGAAAACGAACATTCAACAAAAAGGTTCCTTCAAAAAACGGACGTTGTAGAGGGTTGCGATAACGACAAGTGCGAATGGCCCATTTACATTTGTAATATCTGCGGAACCCAGTTGCCAAATTTCTCTAGCTTTATGTTACACATGGACAATCATATACCGGGAACGGACAGGAACAGTACCATATTTTTGGACTATTGTCCTTTGTGTGGGGAGCCTTGCAGGGACCAGGTGGAGGTAAACAATCACATCCTGGTCCACGCCATCTCCTTGAAATTGGGAAAGTGCTGTAGCATTTGCAAAAAGGTCTTTAATTACAATTCAGACGAATTGCAGAGGCACATGGTCGACGTACACGTCTCAACCACTTACAAATGCTCCATTTGTGAAGACACCTTTGATATTAAGTCAGAAGTACTGatacACATGACAAAAAAGCATAGCAACGAATGTCAACATTATCGTTGTAAATTTTGTCCTGACCAAACATTCCATGATCGTGTTGATGCTGAGGTCCACATCTCCCAACATTCTCCCCAACTTCTAAACACTTTATGCAGAAACACAAACCGCCTTATCTACCCTTCCATTAACAATTCCAATAGTGGTGGATTGCTGCAGCAAAAGAAGTCGAAAACATTTCAGTGTCCTTTCTGTCACAAATGTTTCCAGACTGAGCAACACCAATACCTTCACATAATAAGGGAGCACAAGGATATTCGTGACATGTACAGGAAGAGGGTCCTCGAAATAAACCCAGATGCCCAAAGGCAACTACAGTCAACATCTCCAAGCATTTCTTCACTGAATTCTGTCCCAAATGCTGacctttcaaataaatatgagGTGAACCATGATCGTTATAAATGTGACATTTGCGACTGCAAAGATTTTGTTAACGAATCTGACTTTTTGGCCCACAAGAAGCTCCACCAGTCAAAATCCAAAGCGATATCAGTCAGCCTCCACTGTGCTTACTGCAATGAACTTTGCAAATCTCGGACTGATTTAGAAAACCATACAAAGAGTCACCAAATAAATTCGGCCAAAGGAAAACACAAATGTAATATCTGTGACGAAATATTCCAGTCTGGAATGACCCTTGCTGAACACAAACTGTCCCATTGTAAAATTGTTTCGGGAAATTCCTGTACCCATTGCAGAACTGTCCTTTCCGACGAACAGACTTTCTACAACCACCAACTCCAACACAGCACCGTTCTTAACAAGCAAAACTCACAAATGTCTCTTCCGGCCAACTGTATTATATGTTGCCAAACGTTACAGAGCGAAGTCGAAATTAAACTCCATGCAAATTTCCATTTGAGGCATCTGCTGAACAAGGATTTGATTTGCAGTATCTGCAAGAACTCGTATGATAGTACCAATGGACCTTTGATATCAACAGCAAATAGTGACAATacaattttgtatatttgtaaaGAATGTTTTAGTAAAAATGGTACCAGCAGCACTTCCAATAGTCCCCTATATCCCATTATCAAATACGAGACTGATGATAAGGTGACCACTTGTCCCCACTGTCATCAGGTCTTCCAAACAGAAGAAAAGGCTATGAAGCATTTAGCTTCCCATGGTGTTTTCGACACAGGATCGAGTTATGTGTGCCACCTCTGTCGTAGTTTTTTCCCGACACCCTTAAAACTCCAAGTGCATGTCAtagaacataattttttcgGTTCCGGTCAGTTTAGATGTTACATTTGCAGTACCATTTTTACCACAGCTTCGGGCCTGTTGTCCCACATGTTGAAGCACGGCTCGAACGCGAAACCTTACGAATGTTCGCAATGTCAAATGAAGTTTTTCTTTCAAACCGAACTTGATAATCACCGTGATGACCATTTAGCATCGATTCATCACAAGGGTTACCAAACAGTAACTTTTTCGCCAAATTCGAGCGAAGCAAACGATTTGGTACCGAATAAACAGCAACACTGTCAGTGTTACGAGTATCCATGGTCCCCATCAGCTTCagaaaaacatttacaacattGCCCTTTGAAGGTCACAATTAAGAAAGAGTTAAGGTCAAGTGTTTCGCCCAAGAATgagtttaatttgaaaaaagaagATGGGGACGCCTGCACTTCTACTCCTTCGGATGTTGAACgatga
Protein Sequence: MSRRKQPNPAKLEETEIPNTDHTYKTNSNTAQSQVKEEEEADGNFQRNNFESSTDNNDENYVKVEPFDQEDHEDSLGSVGTNQASWDSNTPEQASPASSSCPTPSSIVSDVTDAEVFTVGVTETTPYACKICNKAFAKTSQLTRHEQTHSDHLQYNCIYCPRLFKHKRSRDRHIKLHTGDKKYKCSFCDTAFSRSDHLKIHLKTHDNSKPFKCFLCNRGYNTAAALTSHQQSHIKQDKDNKDHNNSSESHACSYCSETFQKLELLQAHTSSHHLEPLTEEGNGDGTKWLCMYCTKDFLSLDELQQHVNNSHDVVTDSKSDDSSCKSSINNSSQIINQVQRVSYPCYNCTMQFYCLEKLRDHMARVHWGATTQQKLLSNAVLKDCNICLPISQNCSAPPPSLTQTSTDHSIQLLPTDLSWKRKAELSDENEHSTKRFLQKTDVVEGCDNDKCEWPIYICNICGTQLPNFSSFMLHMDNHIPGTDRNSTIFLDYCPLCGEPCRDQVEVNNHILVHAISLKLGKCCSICKKVFNYNSDELQRHMVDVHVSTTYKCSICEDTFDIKSEVLIHMTKKHSNECQHYRCKFCPDQTFHDRVDAEVHISQHSPQLLNTLCRNTNRLIYPSINNSNSGGLLQQKKSKTFQCPFCHKCFQTEQHQYLHIIREHKDIRDMYRKRVLEINPDAQRQLQSTSPSISSLNSVPNADLSNKYEVNHDRYKCDICDCKDFVNESDFLAHKKLHQSKSKAISVSLHCAYCNELCKSRTDLENHTKSHQINSAKGKHKCNICDEIFQSGMTLAEHKLSHCKIVSGNSCTHCRTVLSDEQTFYNHQLQHSTVLNKQNSQMSLPANCIICCQTLQSEVEIKLHANFHLRHLLNKDLICSICKNSYDSTNGPLISTANSDNTILYICKECFSKNGTSSTSNSPLYPIIKYETDDKVTTCPHCHQVFQTEEKAMKHLASHGVFDTGSSYVCHLCRSFFPTPLKLQVHVIEHNFFGSGQFRCYICSTIFTTASGLLSHMLKHGSNAKPYECSQCQMKFFFQTELDNHRDDHLASIHHKGYQTVTFSPNSSEANDLVPNKQQHCQCYEYPWSPSASEKHLQHCPLKVTIKKELRSSVSPKNEFNLKKEDGDACTSTPSDVER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00030482; iTF_00031309;
90% Identity: iTF_00030482;
80% Identity: -