Basic Information

Insect: Agrilus biguttatus
Gene Symbol: Znf423
Assembly: GCA_963921985.1
Location: OY998127.1:4981335-4987423[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 2.4e-06 0.00017 22.1 0.9 1 23 79 101 79 101 0.98

2 21 1 72 4.4 3.7 1 23 107 129 107 129 0.94

3 21 1.1e-06 7.4e-05 23.2 3.6 1 23 135 157 135 157 0.99

4 21 0.00017 0.012 16.3 0.6 1 23 163 185 163 185 0.98

5 21 0.00051 0.036 14.8 2.4 1 23 200 222 200 223 0.95

6 21 0.93 65 4.5 0.2 3 23 244 265 243 265 0.95

7 21 1.6 1.1e+02 3.8 2.0 1 23 297 320 297 320 0.96

8 21 0.0039 0.27 12.0 0.2 1 23 409 431 409 431 0.97

9 21 0.0013 0.088 13.6 0.1 2 23 445 466 444 466 0.96

10 21 0.021 1.5 9.7 1.5 3 23 476 498 474 498 0.80

11 21 0.035 2.4 9.0 0.4 1 23 503 526 503 526 0.97

12 21 9.5 6.6e+02 1.4 0.9 1 23 533 556 533 556 0.89

13 21 0.2 14 6.6 6.0 2 23 593 615 592 615 0.94

14 21 0.96 67 4.5 1.4 1 23 666 689 666 689 0.93

15 21 0.11 7.5 7.5 4.4 2 23 701 722 700 722 0.96

16 21 0.02 1.4 9.8 0.6 1 23 731 753 731 753 0.96

17 21 0.62 43 5.1 0.9 2 23 761 782 761 782 0.96

18 21 0.018 1.3 9.9 2.6 2 23 889 910 888 910 0.96

19 21 0.04 2.8 8.8 0.5 1 23 919 941 919 941 0.96

20 21 9.9e-05 0.0069 17.0 0.3 1 23 949 971 949 971 0.98

21 21 0.054 3.8 8.4 1.6 1 23 978 1000 978 1000 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	2.4e-06	0.00017	22.1	0.9	1	23	79	101	79	101	0.98
2	21	1	72	4.4	3.7	1	23	107	129	107	129	0.94
3	21	1.1e-06	7.4e-05	23.2	3.6	1	23	135	157	135	157	0.99
4	21	0.00017	0.012	16.3	0.6	1	23	163	185	163	185	0.98
5	21	0.00051	0.036	14.8	2.4	1	23	200	222	200	223	0.95
6	21	0.93	65	4.5	0.2	3	23	244	265	243	265	0.95
7	21	1.6	1.1e+02	3.8	2.0	1	23	297	320	297	320	0.96
8	21	0.0039	0.27	12.0	0.2	1	23	409	431	409	431	0.97
9	21	0.0013	0.088	13.6	0.1	2	23	445	466	444	466	0.96
10	21	0.021	1.5	9.7	1.5	3	23	476	498	474	498	0.80
11	21	0.035	2.4	9.0	0.4	1	23	503	526	503	526	0.97
12	21	9.5	6.6e+02	1.4	0.9	1	23	533	556	533	556	0.89
13	21	0.2	14	6.6	6.0	2	23	593	615	592	615	0.94
14	21	0.96	67	4.5	1.4	1	23	666	689	666	689	0.93
15	21	0.11	7.5	7.5	4.4	2	23	701	722	700	722	0.96
16	21	0.02	1.4	9.8	0.6	1	23	731	753	731	753	0.96
17	21	0.62	43	5.1	0.9	2	23	761	782	761	782	0.96
18	21	0.018	1.3	9.9	2.6	2	23	889	910	888	910	0.96
19	21	0.04	2.8	8.8	0.5	1	23	919	941	919	941	0.96
20	21	9.9e-05	0.0069	17.0	0.3	1	23	949	971	949	971	0.98
21	21	0.054	3.8	8.4	1.6	1	23	978	1000	978	1000	0.94

Sequence Information

Coding Sequence: ATGAAAATGCTTTTCAAAGGAAATAGTTCAACATTGGAATTACTCATAGAAAAAATACAATCAAAAAAGGAAGAAATATTAGAAGGATCAGTTGGAACAAATCAAGCCAGCTGGGATTCGAATACACCAGAGCAGGCATCCCCAACGTCCAGTTCGTGTCCTACACCCAGTTCAATTGTAAGCGATGTTACAGATGCGGATGTTTTTACAGTGGGTGTTACAGAAAGCACCCCGTACGCGTGTAAAATATGCAACAAAGCATTTGCAAAAACTTCACAACTTACTCGCCACGAACAGACTCATTCCGATCACTTACAGTACAACTGTATATACTGTCCCCGATTATTCAAACATAAAAGGTCAAGGGACAGACATATTAAACTTCATACCGgagataaaaaatacaaatgttcCTTTTGTGATACTGCGTTTTCAAGAAGCGATCACTTAAAGATCCATTTGAAAACTCACGACAATAGTAAACCTTTCAAATGTTTTCTATGTAATCGGGGCTACAACACGGCAGCAGCCCTAACATCTCACCAACAAAGTCATATTAAACAAGACAAAGATAAGGATCAAAATAATTCAGAAAATCATTCATGTTCGTATTGTTCGGAAACATTTCCAAAGATAGAATTATTACAGGCTCATATGTCTTCACATCATCTGGAGCCTTTAACAGATAACGCCCAAGAAGACGGCAACGATGATGGTACGAAATGGTTGTGTATGTATTGTGCTAAAGATTTTTTATCGCTAGACGAATTACAACAGCACGTAAATAATTCTCACGATGTTATAACTGATTCAAAGAGTAACGATTCCTCCTGTAAATCTTCGGTAAATAATTCGtctcaaattattaaacaaGTCCAGCGTGTCTCGTATCCTTGTTACAACTGTACAATGCAATTTTATTGCCTTGAAAAATTAAGGGACCACATGGCTCGAGTTCACTGGGGAGCGACGACACAACAGAAATTCCTCTCCAATGCCATTTTAAAAGATTGCAATATTTGTCTTCCTATATCCCAGAATAGCAGTGCACCTCCACCCCCTCTAACACAAACCTCTAGCGATCATGCCATTCAATTATTACCTACGGATCTAACTTGGAAACGTAAGGCGGAATTGTCTGACGAAAATGAACATTCGAAAAGGTTCCTTCAAAAAACAGACGCTGTCGATGGTTGTGATAACGACAAATGCGAATGGCCTATTTACATTTGTAATATCTGTGGAACACAGTTGCCAAATTTCTCTAGCTTTATGTTACATATGGACAATCACATACCGGGAACTGACAGGAACAGTACCATATTCCTGGATTATTGCCCTTTGTGCGGAGAGCCTTGTCGAGACCAGGTTGAAGTGAACAATCACATCCTGGTTCATGCCATCTCCTTGAAATTGGGCAAATGTTGTGGAATTTGCAAAAAGGTCTTTAATTACAATTCCGATGAATTGCAAAGGCACATGATGGACGTACATGTATCGACCACTTACAAATGCACCATTTGCGAAGACACGTTTGACATAAAGTCAGAAGTATTGATTCACATGACAAAGAAGCATAGTAACGAGTGTCAACATTATCGATGTAAGTTTTGTCCAGATCAAACATTCCATGAACGTGTTGATGCTGAAGTGCATATTTCCCAACACGCTCCCCAACTTCTAAATACATTATGTCGAAATACAAACCGCCTTATATACCCAACCATTAACAACTCTAACAACAGCGGATTACAACAAAAAAAGTCGAGAACACTGCAATGTCCCTTCTGTCACAAATGTTTCCAAACGGAGCAACATCAATACCTACACATAATAAGAGAACACAAAGATATTCGTGAAaTGTATAGGAAGAGAGTTTTGGAAATAAATCCCGATGCCCAACGTCAATTACAGTCTACATCTCCGAGCATTTCGTCTTTGAATCCTGTTCCATCTTCCGATCTTTCAACGAAATACGAAGTGAACCATGAGCGTTATAAATGCGACATTTGCGATTGTAAAGATTTTCTTAACGAAAATGATCTGTTAGCCCATAAGAAACTTCATCAGTCGAAATCGAAAGCGATTTCTGTTAGTCTTCATTGCGCATACTGTAACGAACTCTGTAAGTCTCGGACTGATTTGGAAAATCATACAAAGAGTCATCAAATTAACTCAACTAAAGGAAAACACAAGTGCAATATCTGCGACGAAATATTCCAGTCTGGAATGACTCTTGCGGAACATAAATTGTctcattgtaaaattgtttcgGGAAATTCCTGTACGCTTTGCAGAACTGTCCTTTCCGATGAACAAACATTCTACAATCACCAACTGCAACACAGTACCGTTCTTAACAAGCAAAACTCACAAATGTCTCTTCCTGCAAACTGCATTATTTGTTGTCAAACGTTACAAAGCGAAGTTGAAATAAAACTGCATGCAAATTTCCATCTCAGACATTTACTGAACAAAGAGTTGATTTGTAGCATTTGCAAAAATTCCTACGACAGTACGAATGGGCCTCTAATATCCACAGCGAATAATGACAATACGATTTTGTATGTTTGTAAAGAATGTTTCAGTAAAAATGGTACCAATAGCACTTCAAATAGTCCATTGTATCCCATTATTAAATACGAAACTGAAGAGAAGGTAACCACATGCCCCCATTGCCATCAGGTCTTTCAAACGGAGGAAAAGGCTATGAAACATTTGGCTTCCCATGGTGTTTTCGACACAGGATCTAGTTACGTGTGCCATCTATGTCGAAGTTTTTTTCCAACACCTTTGAAACTCCAAGTGCATGTCATAGAACATAATTTTTTCGGTTCAGGCCAGTTCAGATGTTATATTTGCAGCACCATTTTTACCACTGCTGCAGGTCTACTGTCCCATATGTTGAAGCACGGCTCGAACGCGAAACCTTACGAATGTTCGCAATGTCAGATGAAATTTTTCTTTCAAACCGAATTGGATAATCATCGTGATGACCATTTGGCATCTATACATCACAAGAATTACCAAACTGTGACATTTTCACCACATTCCAACGAAACAAACGATTTGTCATCGAACAAACAACAACATTGCCAGTGTTATGAGTATCCTTGGTCTCCGTCAACTTCCGAAAAGCATTTACAACATTGTCCCCTAAAGGTAACCATCAAGAAAGAGTATAGGTCTAGTGTTTCACCGAAaaacgaatttaatttaaaaaaagaagatggAGATGCGAGCACTTCTACACCTTCCGATGCTGAACGATGA
Protein Sequence: MKMLFKGNSSTLELLIEKIQSKKEEILEGSVGTNQASWDSNTPEQASPTSSSCPTPSSIVSDVTDADVFTVGVTESTPYACKICNKAFAKTSQLTRHEQTHSDHLQYNCIYCPRLFKHKRSRDRHIKLHTGDKKYKCSFCDTAFSRSDHLKIHLKTHDNSKPFKCFLCNRGYNTAAALTSHQQSHIKQDKDKDQNNSENHSCSYCSETFPKIELLQAHMSSHHLEPLTDNAQEDGNDDGTKWLCMYCAKDFLSLDELQQHVNNSHDVITDSKSNDSSCKSSVNNSSQIIKQVQRVSYPCYNCTMQFYCLEKLRDHMARVHWGATTQQKFLSNAILKDCNICLPISQNSSAPPPPLTQTSSDHAIQLLPTDLTWKRKAELSDENEHSKRFLQKTDAVDGCDNDKCEWPIYICNICGTQLPNFSSFMLHMDNHIPGTDRNSTIFLDYCPLCGEPCRDQVEVNNHILVHAISLKLGKCCGICKKVFNYNSDELQRHMMDVHVSTTYKCTICEDTFDIKSEVLIHMTKKHSNECQHYRCKFCPDQTFHERVDAEVHISQHAPQLLNTLCRNTNRLIYPTINNSNNSGLQQKKSRTLQCPFCHKCFQTEQHQYLHIIREHKDIREMYRKRVLEINPDAQRQLQSTSPSISSLNPVPSSDLSTKYEVNHERYKCDICDCKDFLNENDLLAHKKLHQSKSKAISVSLHCAYCNELCKSRTDLENHTKSHQINSTKGKHKCNICDEIFQSGMTLAEHKLSHCKIVSGNSCTLCRTVLSDEQTFYNHQLQHSTVLNKQNSQMSLPANCIICCQTLQSEVEIKLHANFHLRHLLNKELICSICKNSYDSTNGPLISTANNDNTILYVCKECFSKNGTNSTSNSPLYPIIKYETEEKVTTCPHCHQVFQTEEKAMKHLASHGVFDTGSSYVCHLCRSFFPTPLKLQVHVIEHNFFGSGQFRCYICSTIFTTAAGLLSHMLKHGSNAKPYECSQCQMKFFFQTELDNHRDDHLASIHHKNYQTVTFSPHSNETNDLSSNKQQHCQCYEYPWSPSTSEKHLQHCPLKVTIKKEYRSSVSPKNEFNLKKEDGDASTSTPSDAER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00032310;
90% Identity: iTF_00032310; iTF_00031309;
80% Identity: -