Basic Information

Insect: Agrilus biguttatus
Gene Symbol: ubtf-b
Assembly: GCA_963921985.1
Location: OY998127.1:6202785-6205177[+]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.7e-20 1.7e-17 63.8 6.9 1 68 162 229 162 230 0.97

2 5 9.2e-11 5.9e-08 33.3 0.5 1 69 248 314 248 314 0.97

3 5 1.6e-06 0.001 19.7 1.5 2 68 347 411 346 412 0.83

4 5 4.3 2.7e+03 -0.9 0.1 3 15 494 506 493 515 0.77

5 5 0.0074 4.7 8.0 3.2 33 68 510 545 503 546 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.7e-20	1.7e-17	63.8	6.9	1	68	162	229	162	230	0.97
2	5	9.2e-11	5.9e-08	33.3	0.5	1	69	248	314	248	314	0.97
3	5	1.6e-06	0.001	19.7	1.5	2	68	347	411	346	412	0.83
4	5	4.3	2.7e+03	-0.9	0.1	3	15	494	506	493	515	0.77
5	5	0.0074	4.7	8.0	3.2	33	68	510	545	503	546	0.90

Sequence Information

Coding Sequence: ATGGGTTCTAAACGTAAGGATAGATCTGAAAAATCAGATGAAggggaaaaaaagaaaaaacataaaaaggtcaaaataaaagaagaacCAACTAGTGATATTGAAATTGAAGACACCAAAGTTAAAGATTCAGATCACTTAAATGTTTTCAAAGAAGAACCAATAGAGCATGTTGACCATGAAGATAATGAAACTATTAGCATGCGTGAAGAAGATTTATCAGAGCTTTTTAGTAAGATAGAACAAATTCTTCCTGAACAAGATACAATGTCTTATAGTACACGAGTAGAGAAACTCAAATGGGAAGATgtaGCTTTTAAGAATTATTCTGCTGAAGAGTGCAAAAAAACTTGGCTCCTTGTTCAAAAAAGAGTACGAAGGTTTAGAATTTTGAAAGAACTTCTTCATGATGCAAAAGATTGGTTAAATAAACCATGGACCAATTTTTATCGTGGTAACAAAATGAACCGTCACCCTGATATGCCAAGAAAGCCATTATCTTCATACATGATATTTTACAAGAAAAAGAGAGACAAAATCATAAAAGAGAAACCAGGAATGGATATTACTGAAGTAACTAAAATTATTGCACAAATGTACAAGTCTATATCTCCAGAAAAGAGGCAAAAATATAACAAACTTGCAGCTGAACAGAAAAAACAGTATGAAGAAAAATTACAAGAGTTTTACAACCAACATCCAGAAATACCAAGACTTGTTAACAAATCTGTTACCCAAGGACCAAAAAGACCCCTTACACCATTTTTGCTTTTCTTTCAAAGCCAAATTAAAAACATGGCTCCTGAGGATATTGATAAAGCAACTATTAAAGAGCAATGCAGAGAGCTTTGGAAAAATTTTCCTGATAAAAAGAGACTTGTTTGGATAGAGTTAGCTTTAGAACATGAAGCAAAATATCTTCAAGATGTTAACAAATACAAAGAAATGAACCCTGACTTTGAACCTCCAccatttaaatctattttaactaaagaagaaaaagcTCTCAAAGAACGACTCTTAGATGGAAAACCTGTCAAACCTCCTAATTCAGCTTACAGTTTATTTTCTACAAAGATGCTACAAAGTGAAGAAATAAAAAGCTGTCCATTAAAGGACAGAATGAATTATATTTCAGGTTTATGGAAGAATATGAGTGACTTGGAGAAGAAAGAGTATATTGATCAGACAAAACAGTTAATAGAACAATACAAGTTAGATTATGCAAGTTATATTAAAGCACTTCCCAAAGAAAAGCGTCAAGAAGAACTGAAGACCCTTTCAAAGAGAAAACAGAAATCCATGAATGAAATCAATAATCATACTCCAAAGAAAAAGCGAAAAGAGAAAGCAGTAAAAGTAGATGTGAAAGAGGAAGAAGTGCATGAAGAGGTCAGCTTAAGTGAACAGCCTTTGGAAGATGATAATGAAGTTGAAGAATCATTAATGGCTAAAATTGTTTCCTTAGAACCTGAACAGCCTCCATTGAACGCATTTGGtttgtttcttaaaaattattctGGAAAAAAGCTGGCAAAGGAAGAATTCAATAAACTAGGCCGAGCAGAAAAACGTAAGTTGGAAAAAGAAGTGCAAAATTTGAAGAAAGCTTATATTAAAGACTATGAAGAATTTCTGAATGGTTTAACAAAGAAGCAGTTAAAAACTTTTTCGAAATGGTCAAAAAAGAGGGATGAGAATAAGAAAGATTCTGAAATAAGCAAAATTGGAAAAGCTGAAGCTGAAGTATCATCATCTTCTGATTCAGAATCAGATTCATCTAGTTCGTCGTAA
Protein Sequence: MGSKRKDRSEKSDEGEKKKKHKKVKIKEEPTSDIEIEDTKVKDSDHLNVFKEEPIEHVDHEDNETISMREEDLSELFSKIEQILPEQDTMSYSTRVEKLKWEDVAFKNYSAEECKKTWLLVQKRVRRFRILKELLHDAKDWLNKPWTNFYRGNKMNRHPDMPRKPLSSYMIFYKKKRDKIIKEKPGMDITEVTKIIAQMYKSISPEKRQKYNKLAAEQKKQYEEKLQEFYNQHPEIPRLVNKSVTQGPKRPLTPFLLFFQSQIKNMAPEDIDKATIKEQCRELWKNFPDKKRLVWIELALEHEAKYLQDVNKYKEMNPDFEPPPFKSILTKEEKALKERLLDGKPVKPPNSAYSLFSTKMLQSEEIKSCPLKDRMNYISGLWKNMSDLEKKEYIDQTKQLIEQYKLDYASYIKALPKEKRQEELKTLSKRKQKSMNEINNHTPKKKRKEKAVKVDVKEEEVHEEVSLSEQPLEDDNEVEESLMAKIVSLEPEQPPLNAFGLFLKNYSGKKLAKEEFNKLGRAEKRKLEKEVQNLKKAYIKDYEEFLNGLTKKQLKTFSKWSKKRDENKKDSEISKIGKAEAEVSSSSDSESDSSSSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00031001;
90% Identity: iTF_00031910;
80% Identity: -