Basic Information

Insect: Agonum fuliginosum
Gene Symbol: -
Assembly: GCA_947534325.1
Location: OX384040.1:11728345-11733335[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.3e-14 1.5e-10 42.0 0.0 8 70 226 289 221 293 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.3e-14	1.5e-10	42.0	0.0	8	70	226	289	221	293	0.88

Sequence Information

Coding Sequence: ATGAGTACCAGTGAAGGTGAGAAAACAGAGGAAAGCAAAAATGAATCGGCAGAAGAAAGAATATCTACTCCAGTTAATGAAACGGCAGAAACCGAAACGTCGTCAGGCCTCAATGGTGATACAGAGATGGACGTTGACGAGAATTCTTTAGAAGATAGCAAAGATCCTGAAGACATTGTAGAGGAGAATAAGGTGGAAAATGAATCTGAAGACGATCCAGCGCCTCCCAAGAAACGAAAATTCAATGATTCTGGTGAATTATCGGACGATTCATCCTCAACAGAATTTTTAGGATTCCCAGACACGCGTACTGAAGAAGAGAAAAAAGCTGCTGCTTTTGCTGCTGCTGCTAAAAAAGAAAAGGAAGAAAAAGTGAAATTAGATTTATTAACATTCGATGCTGCAGCATTTGGAAAAGGCAAACGTTCAAGAGTACCTAATAAGAGATATCAAGGATTATCATCAACTATTAGATTTTCCAAAAGTTCACACAGACATAGTGAGCATCTAGATAATGATAGTGGGCATGAAGATAGAAATTTTGATGAAAACGATGATGAAGTATCAAGTAGTCATAGTAGTCCTCGTGCTAAATCACGTGTACCTGCTAGCCCTGCTACACCAAGCCATACACAGAAGAAAGCAAAGGTTGTTGACATGACAAATCCAAACTTTTTAAAACCGTTTGAATTGGGTTGGAAACGTGAACTTGTTTACCGTGCAACAATGGACAACAATATGAGAAGAAATGGCGACATTTATTATTATACACCAACAGGAAGAAAAATGCGATCCATGCGCGAACTCACAGATACGTTAAGAATAGACAAAATAACTGAACTAACTGTAGATGATTTTACATTTTTCAAAGAACCAGTTGGGATTAACGATCCCGAAAAGGAAATCATCAGAGAAGCAAAATACAAAAAAAATTCATCGCTTCTCAAAAGTGGAAAAGCTAAAACTCCTAGTAAAAATTCCAGCCCTAAAGTAGCAGCTCTAAATGAATCAAGTTCAAAAAATGCAAAATCACCACGATTAGGCGGATTTAAGGTCAAAATCACAGGTTCTTCAAAATTAAATCAAGGATCTAATAAAAAAGATAATAAACGTGCATCTGCAGACAATGATCTGGAAATCGGAATGCTGCCACCTGCTTGGTCTCCGAAAAAAGGATCTTCGGCAAAGCAGTCCAATTATTTAAAAACTGGCAGCTTAGCGGGCTCTCCATTGGATGCTAAACCGTGTCGACCGTGTTCCATCCGCTGCCAGGGCGTATCTGGTATTATACCCACACTGCAGTGCCGACTTTGCCTCTGCCTCTATCACAAAGAGTGCGTTGGAGAACTTTCCGACGACGTACCGGGTGGCTACGTGTGTAAGAACTGCCAACTGGACAATCAAGACAAAATTGAATCAGCATTTGAACCTGCCCCTCCGATAGGTCCGCCACCATTAACTCCAATTAGTTCCTTAAAATCCAATAATACTCAATCCGCTACTCCGCCAAAATTACAAAGGATTCCTAGACCTGGTGAGAAGGCATTTATTCCATTACCCACTCAACATGTTCCTAAACTTAACTCAATTCCCGAGCCGCTTAAATCGCATCTTATTAAATACCCTCCAACATTATATAACTTGGCAGCTCAAACCGAACCCAGTAAAAGTATTGTCGGTTCTGTTACAACATGGTTTCCTCCAAATTCTACACTTAAAATGAATGCAAGTAATTCGCAAAATAAAAATTCAACGGATATATTAACAACTAAACCACAGAATGTAGTATTTATGGGCGAAAGAAAATTTCTAGTTGTTCCCAAGGGTAACGTATTGTCTATATCACCAACATTAGGTGCCGCGGTAAATACTCCCAGTGCTAAACGTGTTACGTCCCCCACTGCTGACAAAGCCCCAGTATTTGATGGGAAAGAGATTGGCGGTAATAAAACTGTAGAAGGCGCTTCTTCTTTTGATTCCGTGCAAAAAAATTCTGTCCCAGCAAATGAATCTCCACTATCTAGTTTAACATCCGTACTCCATCCTAGTGATAAGTCCAGCCTTTCAGCAACTATTGAAAGACCGACAATCCCAATGTCTAGTGATCTGCTGGTTGTCAGAGAAGAAATCAGCAGCGCGACAGGAGAAACGCTTAAAGAAAATCAAATAGAAGCCACACCGCCAAAAACGAGAAGAGGAGGTGCGAGTAAGAAAACACCAACTGTTTCTATGCCAATTATAAAGAATGATGCAGAAACACGTTTCATGCAAAATTATTTACAAAATTTGTCTTATGGTTATCAAACTTTACTTTACGTGTTCCAATACTTAAAAGTGCAAGATTTGTTACGAGCCGGTTGTGTGTGTACTTTGTGGAGAGATATTGCTGGCCATCCAAGTCTTTGGAATACAGTTAGAATGAAAAATTCTCAAGTTGCTAATTGGGAAGGTTTGGCAGATGCTTTGAAAAAACACCGAACAAAAAATTTAGATCTACGTAAAATGTTATTACCTAACACAGGTGATGATATGTGGGCTCAGTTTTCAAAAGCCATCGCAAGAGTTGATTCATTAGTTAGAATAGAATTATGTCGGTGCCCTGCTTCAGTCATTGAACAGCTTGCAACGACAAATAAAAGTTTGCAAGTCATAAATGCTGTGATGATTAGATGCGAATCTATGGATATTTCCGCTTTGGATAATTTAGAAAATCTGCAGGAGTTAAGATTAAAATCTACAAACGGATTTGTTTTAACATCAGATTTAACACCACTTAAAACCTTAACAAAACTAAAACATCTTTCTTTGACATCAATTAAAGACTTACATAAACAAAACGTTCAAATCATAGGAGATTTAATAAATTTGGAGACATTAGATCTTGGTGAATGTAGTGATTTCCCGGATAATTTTGGTACAGATGTAATTACAAAATTAACAAAATTAGAAAAGTTACGATTAGAAAAAGGACAAGGTTCTTGTTGTACTTTTAACATTTTAGACGCTGTAAGTAAAATTCCGTGTTTAGAGCAATTAGAATTGGTCAACTTTGACGTAAAAGCGGGTTTCGATAAATCTTTGGGTGCGTGTGTAAACATTAAAAAATTATTAATAATTCCCACATACATATCTCAATCAGCAACAACAAATCACATGGTGTTAGGAGGTGTTATCAAGTTAAAATCTACACTTTCTCACTTTGTATGGGGAGTTACGTTAGAATTGTTAAGAGTAACAGAACTCTTTGTCGACCAATGTGAAGATTCTCCCAATAAGGATAAGAAGAAACCGACGGGGAATGGAGACAGTATACCAGTTCTCAAACCAGTGCCGATAATGAAAACAGATGAATCAAAAGATGAGTCGTCGAGTAAAGAGCAACCACAAGTTGAAATTTTACCTCTGCCTACATTACAGAAATTACTTTTGAATTGTTTACCGACAACAAGAGTAAAAATACTAAAAATACCTTTCCATGCAACATGGCGACAGAGCATAGTAGACACTGTGAATTAG
Protein Sequence: MSTSEGEKTEESKNESAEERISTPVNETAETETSSGLNGDTEMDVDENSLEDSKDPEDIVEENKVENESEDDPAPPKKRKFNDSGELSDDSSSTEFLGFPDTRTEEEKKAAAFAAAAKKEKEEKVKLDLLTFDAAAFGKGKRSRVPNKRYQGLSSTIRFSKSSHRHSEHLDNDSGHEDRNFDENDDEVSSSHSSPRAKSRVPASPATPSHTQKKAKVVDMTNPNFLKPFELGWKRELVYRATMDNNMRRNGDIYYYTPTGRKMRSMRELTDTLRIDKITELTVDDFTFFKEPVGINDPEKEIIREAKYKKNSSLLKSGKAKTPSKNSSPKVAALNESSSKNAKSPRLGGFKVKITGSSKLNQGSNKKDNKRASADNDLEIGMLPPAWSPKKGSSAKQSNYLKTGSLAGSPLDAKPCRPCSIRCQGVSGIIPTLQCRLCLCLYHKECVGELSDDVPGGYVCKNCQLDNQDKIESAFEPAPPIGPPPLTPISSLKSNNTQSATPPKLQRIPRPGEKAFIPLPTQHVPKLNSIPEPLKSHLIKYPPTLYNLAAQTEPSKSIVGSVTTWFPPNSTLKMNASNSQNKNSTDILTTKPQNVVFMGERKFLVVPKGNVLSISPTLGAAVNTPSAKRVTSPTADKAPVFDGKEIGGNKTVEGASSFDSVQKNSVPANESPLSSLTSVLHPSDKSSLSATIERPTIPMSSDLLVVREEISSATGETLKENQIEATPPKTRRGGASKKTPTVSMPIIKNDAETRFMQNYLQNLSYGYQTLLYVFQYLKVQDLLRAGCVCTLWRDIAGHPSLWNTVRMKNSQVANWEGLADALKKHRTKNLDLRKMLLPNTGDDMWAQFSKAIARVDSLVRIELCRCPASVIEQLATTNKSLQVINAVMIRCESMDISALDNLENLQELRLKSTNGFVLTSDLTPLKTLTKLKHLSLTSIKDLHKQNVQIIGDLINLETLDLGECSDFPDNFGTDVITKLTKLEKLRLEKGQGSCCTFNILDAVSKIPCLEQLELVNFDVKAGFDKSLGACVNIKKLLIIPTYISQSATTNHMVLGGVIKLKSTLSHFVWGVTLELLRVTELFVDQCEDSPNKDKKKPTGNGDSIPVLKPVPIMKTDESKDESSSKEQPQVEILPLPTLQKLLLNCLPTTRVKILKIPFHATWRQSIVDTVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01225685;
90% Identity: -
80% Identity: -