Basic Information

Gene Symbol
-
Assembly
GCA_963924505.1
Location
OZ004687.1:503082-504656[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0012 0.079 13.9 0.4 2 23 164 186 163 186 0.92
2 10 8.2 5.3e+02 1.9 0.8 1 23 192 214 192 214 0.75
3 10 0.21 13 6.9 1.7 2 23 221 242 220 242 0.94
4 10 2.7e-05 0.0018 19.1 0.3 1 21 247 267 247 268 0.92
5 10 7.6e-05 0.0049 17.7 1.3 3 23 290 310 288 310 0.92
6 10 0.00038 0.025 15.5 3.1 1 23 317 339 317 339 0.97
7 10 1e-05 0.00066 20.5 1.3 1 23 345 367 345 367 0.96
8 10 0.00014 0.0089 16.9 2.0 1 23 373 395 373 395 0.95
9 10 0.00075 0.048 14.6 2.0 1 23 401 423 401 423 0.98
10 10 2.1e-06 0.00013 22.6 0.9 1 23 429 452 429 452 0.97

Sequence Information

Coding Sequence
ATGAGTGCCGTCAACTCTTACTGCCGATTGTGCGCTGCACTAAAAACTCTCGACAAACTCATCGATCTAAAGCAAGACGAGACCAAACGTCGAGAAATCGTTGAAAAACTGACTCGTATCTACCCTGGTATAGACTTTACGGACGATGCATTGCCTAAAACCGTGTGTCTAGTTTGCGTTAGCTTCTTAGATAAAGCCTTTGACTTCGTCCTTGGCATAGAACAAGCGCAGGGAGCTTTAACCGACATACTTTTAGTGCAAGAAATAAAGAAAGAGGCTCAAGAATCTGAATTTTCAGACGACGATTTCCCATCCGATCCACCAGAAGTCAAAGACGAAAATGTCAACGTTAAAAGTGAAACAGAAGATGTCGAACCCCAGAAAGTTAAAGAGAGATGCAAAACTAAACAGAAGAGAAAAGGTACACATTTCAGTTTAGATGCGATCCCTTTATCGCAGTTGAAGTTATCGTGGAAAGAATATTTTTGGACGTGTTCGTATTGTGAAACTCAATTCTCAAACATAGACGAACTACGAGCACATTCGATGCAATTCCACGATTGCTGCAACTCGTTCCGATGCGCAGATTGTAATATTAGAAAACTGCGTCTGGACAGCTTTCTCGTCCACGTGCAACGGCATAGAAGATACCTTAAATTGTCCTGTTATAAATGTCATGAACATTTCATATCGTTAACGGAAGCTAATGCGCACAAAGCGGTCCACAAAAACACGAAACACATATGCCCTGGTTGCAACACAACTTTTTCTTCCTCCGAGGAGCTCCAACAACACACTTCTACGTACTATCAAGCTCAGAGATCAAGAACGTTAAAGCTACAAAAAAGTATAACGGACAATCTCACTTGCATCATATGTAAGAAAACGTTTAAACACAAAGGTACTTTAAATGCGCATATTTTAATACATACGGAGAGAAAAAGAGATCACACGTGCGATAAATGCGGCAAATGCTTCCTTAACAAGCAAAACTTAGCCGGCCATATGATTCTGCACGACAACGTACGGCCGTTCCAGTGCGAAATCTGCAAAGCGTGCTTCAAAACTCAAGGCCAACTGCGAAATCATGTCGGAGTGCACGATAATAAAAAACCGTTCGCCTGCGAGCAATGCGGACGATGTTTTCGACTCCAGAAACAACTTACTTCGCATAGCATAATCCATACAGACTCTATGCCATATGTATGTTCGTTTTGCAACAAAGGTTTTCGcttcaaaacaattttaaatcaaCATATTCGTCAACACACTGGAGTAAAACCATATGCCTGCGAAATATGTCAGCGAGATTTCACAAATTGGCCGAATTATAATAAGCATATGAAGCGAAGACATGGTATGGATATGGCTAAGAAAAAGCACACACCAGACGGAGTGTACCCAATCAACCCGGCAACGGGTGAAGTCATTATATACCCGCAAACTAATAAAACTGTGGAATGGAAAAAGCAGTTGTTGCGTCAAAGAAGGCCGGGGCGGCCAAAGGTGGCGTTCAAAAACGAGGAACCCGTAGAAAATAAGAGTACAGAAAATCAGAGTGAAATGAGTCaatga
Protein Sequence
MSAVNSYCRLCAALKTLDKLIDLKQDETKRREIVEKLTRIYPGIDFTDDALPKTVCLVCVSFLDKAFDFVLGIEQAQGALTDILLVQEIKKEAQESEFSDDDFPSDPPEVKDENVNVKSETEDVEPQKVKERCKTKQKRKGTHFSLDAIPLSQLKLSWKEYFWTCSYCETQFSNIDELRAHSMQFHDCCNSFRCADCNIRKLRLDSFLVHVQRHRRYLKLSCYKCHEHFISLTEANAHKAVHKNTKHICPGCNTTFSSSEELQQHTSTYYQAQRSRTLKLQKSITDNLTCIICKKTFKHKGTLNAHILIHTERKRDHTCDKCGKCFLNKQNLAGHMILHDNVRPFQCEICKACFKTQGQLRNHVGVHDNKKPFACEQCGRCFRLQKQLTSHSIIHTDSMPYVCSFCNKGFRFKTILNQHIRQHTGVKPYACEICQRDFTNWPNYNKHMKRRHGMDMAKKKHTPDGVYPINPATGEVIIYPQTNKTVEWKKQLLRQRRPGRPKVAFKNEEPVENKSTENQSEMSQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00028045;
90% Identity
iTF_00028045;
80% Identity
-