Basic Information

Insect: Agelastica alni
Gene Symbol: topi
Assembly: GCA_950111635.2
Location: OX467716.1:31481551-31485389[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0019 0.48 12.6 2.1 2 21 102 121 101 122 0.94

2 14 5.3e-06 0.0013 20.7 1.2 1 23 147 169 147 169 0.98

3 14 0.03 7.3 8.9 2.1 2 23 176 197 176 197 0.94

4 14 0.023 5.7 9.3 0.3 2 20 216 234 215 236 0.84

5 14 0.00038 0.093 14.9 1.1 2 23 291 312 290 312 0.97

6 14 1.5 3.6e+02 3.6 0.1 1 12 318 329 318 338 0.86

7 14 0.0017 0.41 12.8 3.1 2 22 355 375 354 378 0.88

8 14 0.00025 0.062 15.4 0.3 1 23 491 514 491 514 0.97

9 14 0.0067 1.6 10.9 0.2 1 23 518 540 518 540 0.97

10 14 6.3e-07 0.00015 23.6 2.4 1 23 546 568 546 568 0.98

11 14 0.018 4.4 9.6 0.1 1 23 574 599 574 599 0.96

12 14 0.061 15 7.9 2.9 1 23 605 627 605 627 0.86

13 14 3.9e-06 0.00095 21.1 0.3 1 23 633 655 633 655 0.98

14 14 2.6e-06 0.00063 21.7 2.2 1 23 661 684 661 684 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0019	0.48	12.6	2.1	2	21	102	121	101	122	0.94
2	14	5.3e-06	0.0013	20.7	1.2	1	23	147	169	147	169	0.98
3	14	0.03	7.3	8.9	2.1	2	23	176	197	176	197	0.94
4	14	0.023	5.7	9.3	0.3	2	20	216	234	215	236	0.84
5	14	0.00038	0.093	14.9	1.1	2	23	291	312	290	312	0.97
6	14	1.5	3.6e+02	3.6	0.1	1	12	318	329	318	338	0.86
7	14	0.0017	0.41	12.8	3.1	2	22	355	375	354	378	0.88
8	14	0.00025	0.062	15.4	0.3	1	23	491	514	491	514	0.97
9	14	0.0067	1.6	10.9	0.2	1	23	518	540	518	540	0.97
10	14	6.3e-07	0.00015	23.6	2.4	1	23	546	568	546	568	0.98
11	14	0.018	4.4	9.6	0.1	1	23	574	599	574	599	0.96
12	14	0.061	15	7.9	2.9	1	23	605	627	605	627	0.86
13	14	3.9e-06	0.00095	21.1	0.3	1	23	633	655	633	655	0.98
14	14	2.6e-06	0.00063	21.7	2.2	1	23	661	684	661	684	0.98

Sequence Information

Coding Sequence: ATGAACACCcttgataataatataattataaatgtatATAGGATAGAAGAGAACGGGATAGCGAGTTCAGCATTATGGTACGAAATGAATTCAACTACCAAAGAACCTATATCAACCAAAAATTTTTGTCCGATAAACGTGAGTTTCGACCCCAAAATGTTACTTTCCAACGAAAGCATATTTACGTTAAATTTCCAACATTTCGACATCAACGAAGAGCACATCAAATGCATTAAGTTCGAAGAGACGGAAGACGCATCCACCTCATTGGGTAAGCCAGTTTTGAATATACCTACTATGATACGATGCCAAAATTGCGAAACGAATTTTCCTACTAAATATCAGTATCAAAGGCATCAGTGCGAATTTAATGCCGAAAAAGTCGTTTTAAAATCTGACCTTAGTTGTAAGGATGTGGATAATGGAATTCGCGTTAAATACATCTGCGAATTTTGTAATAAGCAATTTGTTAACAGAAATAATTTAGCACGCCATCAATCCAGCCACGAAAATACGCAAGATAACGTGTGCGAACACTGCAACAAGCAGTTTATCAGCGACAATCGCCTGAGAATCCACAAGGAAAACCATTGCAAAAAAGCGGGCGATATTTCAAAGTTTTACAGAAGCGACGTTGCCGTCTGGAAGTGCAAAAAGTGCCACGAAGTGTTTTCTTCACCTTTAACCGCTAACTATCACGTATTGACCTGCGTGAATACCTTAGAAATCGAAGACCAATCAGAGAAAATGCAATATTCTGACGACGACAAGGGCCTAGACGACGAAAACTCCAAcggcagcagcagcagcagcaaagAAATCGTCATTGACGATAAGAACATCGAAAAAGTCATGACGGAACTCCTACTACAATGTGAATTTTGCAACAGAACCTACGCTGAAAAGAATCTGCTGCTGATGCACCAAAGAAAACACACCACGTCTAGAAACTACGAATGCGTCAATTGTTCTAAAATATTCGATTCGTATCCACCCGCTGCCCAACACTGGATGGTGAAATGCTCGGAGTACGTCAACCTCTTCTATTTACCGAAACTGATGTACTGCGAATACTGCGACAGAACGTTCAAGTCACACGAGCTGCTATACACGCACAAGATCAAGAAGAAGCACTACACGTCCAAGCTTCATGTGCCCGCTATCCATGAAACTACCAAAGAGAACGACGGCAACAACAACGCCGAGAAGAGCGTCGACAACAAAGAAATCCTCAACAAACTCATCGAAGACGTTTTGAAAACGCTGGACGTGCCTGTCGCAAACAAAGTCAACGGCCAAGCAGTCGAACCGAGTAAAAAGAACGAGAAAAAGGACAGCGAAGTCGATACGAACAAGATTCATAGTACCGATTTGACAGAAAAGAAGAAGAGAGGCAGAAAGAGGAAATGGCCGAAAAATCAGTGCATTCGTACGAAAAAGTTTAACACGGATGTTAACGAAGGATTTAAATATCAATGCGAAAGATGCGTGAAGGTTTTCAATAACATTGAGGATTTAGAATCGCACCGGGAGAAGGAGCACGCTTCGAATTTCACTTGCGATGAGTGTGGACAGATCCTCCACAGTGCGAAGGCATTAATGATTCACAGTCGCGCTCACAAAATGTTAAAGCCCTACGTTTGCGAAACTTGCGGTCGCAGTTACTCTCAGACTTCCCATCTGTGGCAACATATGCGATTTCATCAAGGTATAAAGCCCTTTGCTTGTCCCCACGAAGGATGCGAAGCCCGATACACCATCAGACCGGATTTAAAAGACCACATTCGAAAGGCACACACGCGTGAACGTCCATTCAAATGCAACGTTTGTGACAAATGTTTTTTAACTGGCTCTGTCTACTACCAACATCGCTTGATACATACCAACGATAGAAGATATGCTTGCGACTTGTGTCCTAAACGGTTTTTCAGAGCAGACGCTTTGAATAATCATAGAAGGATCCACACCGACGAACGTCCTTATCCCTGTCACGTTTGTGGAAGAGAATTCAGACAAAAAGGAGATCGTAACAAACATCTCAGAACGCAGCACCCTGATAcagttttagtttaa
Protein Sequence: MNTLDNNIIINVYRIEENGIASSALWYEMNSTTKEPISTKNFCPINVSFDPKMLLSNESIFTLNFQHFDINEEHIKCIKFEETEDASTSLGKPVLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKSDLSCKDVDNGIRVKYICEFCNKQFVNRNNLARHQSSHENTQDNVCEHCNKQFISDNRLRIHKENHCKKAGDISKFYRSDVAVWKCKKCHEVFSSPLTANYHVLTCVNTLEIEDQSEKMQYSDDDKGLDDENSNGSSSSSKEIVIDDKNIEKVMTELLLQCEFCNRTYAEKNLLLMHQRKHTTSRNYECVNCSKIFDSYPPAAQHWMVKCSEYVNLFYLPKLMYCEYCDRTFKSHELLYTHKIKKKHYTSKLHVPAIHETTKENDGNNNAEKSVDNKEILNKLIEDVLKTLDVPVANKVNGQAVEPSKKNEKKDSEVDTNKIHSTDLTEKKKRGRKRKWPKNQCIRTKKFNTDVNEGFKYQCERCVKVFNNIEDLESHREKEHASNFTCDECGQILHSAKALMIHSRAHKMLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKAHTRERPFKCNVCDKCFLTGSVYYQHRLIHTNDRRYACDLCPKRFFRADALNNHRRIHTDERPYPCHVCGREFRQKGDRNKHLRTQHPDTVLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00736063;
90% Identity: -
80% Identity: -