Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.016 8.1 6.6 0.0 21 47 33 59 26 65 0.86

2 10 1 5.3e+02 0.8 0.0 21 44 61 84 57 93 0.82

3 10 2.5 1.3e+03 -0.5 0.0 20 43 88 111 81 117 0.81

4 10 0.0031 1.6 8.9 0.0 21 48 117 144 100 149 0.83

5 10 0.26 1.3e+02 2.7 0.1 21 43 145 167 141 173 0.88

6 10 0.0018 0.92 9.6 0.4 10 43 161 195 156 200 0.78

7 10 0.21 1.1e+02 3.0 0.0 21 43 201 223 198 228 0.89

8 10 0.22 1.1e+02 2.9 0.0 21 46 229 254 226 262 0.83

9 10 1.6 8.1e+02 0.2 0.0 23 43 259 279 252 285 0.83

10 10 0.022 11 6.1 0.0 21 43 285 307 277 313 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.016	8.1	6.6	0.0	21	47	33	59	26	65	0.86
2	10	1	5.3e+02	0.8	0.0	21	44	61	84	57	93	0.82
3	10	2.5	1.3e+03	-0.5	0.0	20	43	88	111	81	117	0.81
4	10	0.0031	1.6	8.9	0.0	21	48	117	144	100	149	0.83
5	10	0.26	1.3e+02	2.7	0.1	21	43	145	167	141	173	0.88
6	10	0.0018	0.92	9.6	0.4	10	43	161	195	156	200	0.78
7	10	0.21	1.1e+02	3.0	0.0	21	43	201	223	198	228	0.89
8	10	0.22	1.1e+02	2.9	0.0	21	46	229	254	226	262	0.83
9	10	1.6	8.1e+02	0.2	0.0	23	43	259	279	252	285	0.83
10	10	0.022	11	6.1	0.0	21	43	285	307	277	313	0.87

Coding Sequence: ATGAATTCGGACGAGACATCTAACTGCTCAAGGGAAAATCCACTGACTAATATCTGTGAGAAAATGTCTACAGCAACCAATTTAACGGCACATAACGAAGAAAAGCCGTATAAATGTGATATATGTGAAAAAAAGATATCTACAGCATCAGATTTAACAAAGCATTTAAGGACACATACCGGAGAAAAGCCGTATAAATGCGATTTATGTGATCAAGCTTTTTCTCAAGCACATTATTTAACTGTGCATACAAGGAAACATAATGGAGAAAAGCCGTACAAATGTGATTTCTGTGATAAAAGGTTTTCTACATCATCAGCATTAACAAAGCATACAAGGACACATACCGGAGACAAGCCTTATAAATGTGATATCTGTGATCAAGCTTTTTCtcagaaaacaaatttaaaaaaacatacaaggATACatactggagaaaaaccgtatAAATGTGATATCTGTGATCAAAGTTTTTCCCAACCACATACTTTAAAAACCCATAAAAGGACACATACCGGTGAAATTGCGTTTAAATGTGTAATCTGTGATCGTGCTTTTTCTCAAGCATATAATTTAAGAAGGCATGCAATGACACATACCGGAGAAAAACCTTATAAATGTGATATCTGTGAAAAGGGGTTTTGTACATCATTAGATTTAACAAGGCATACAATGACACATACCGGAGAAACACCATATAAATGTGATATCTGTGATAAGGGATTTTGTACATCATTAGAATTAACAAGGCATACAAGGACACATACCGGTGTTAAGCCGTATAAATGTGATATATGTGATCAATCCTTTTCTCAAGCACATCATTTAACGGGGCATACAAGGACACACACCGGAGAAAAGCCTTATAAATGTGATATCTGTGATCAAGCTTTTTCtcagaaaacaaatttaaatactcataaaagGACACATACCAATATAGAgccatataaatatgttatctgTGATTTAGCGTTTTCTAAAgcctcaaattaa
Protein Sequence: MNSDETSNCSRENPLTNICEKMSTATNLTAHNEEKPYKCDICEKKISTASDLTKHLRTHTGEKPYKCDLCDQAFSQAHYLTVHTRKHNGEKPYKCDFCDKRFSTSSALTKHTRTHTGDKPYKCDICDQAFSQKTNLKKHTRIHTGEKPYKCDICDQSFSQPHTLKTHKRTHTGEIAFKCVICDRAFSQAYNLRRHAMTHTGEKPYKCDICEKGFCTSLDLTRHTMTHTGETPYKCDICDKGFCTSLELTRHTRTHTGVKPYKCDICDQSFSQAHHLTGHTRTHTGEKPYKCDICDQAFSQKTNLNTHKRTHTNIEPYKYVICDLAFSKASN

Sequence clustering based on sequence similarity using MMseqs2