Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 6.7 3.4e+03 -1.8 0.0 25 44 88 107 77 111 0.64

2 6 1.2 6.3e+02 0.5 0.0 21 30 138 147 128 154 0.84

3 6 7.7e-05 0.039 14.0 0.0 21 47 166 192 162 198 0.86

4 6 0.3 1.5e+02 2.5 0.0 22 43 195 216 189 221 0.84

5 6 0.00039 0.2 11.7 0.1 21 45 222 246 216 253 0.86

6 6 0.012 6 7.0 0.1 21 48 250 277 245 281 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	6.7	3.4e+03	-1.8	0.0	25	44	88	107	77	111	0.64
2	6	1.2	6.3e+02	0.5	0.0	21	30	138	147	128	154	0.84
3	6	7.7e-05	0.039	14.0	0.0	21	47	166	192	162	198	0.86
4	6	0.3	1.5e+02	2.5	0.0	22	43	195	216	189	221	0.84
5	6	0.00039	0.2	11.7	0.1	21	45	222	246	216	253	0.86
6	6	0.012	6	7.0	0.1	21	48	250	277	245	281	0.86

Coding Sequence: atgaCGCCCAATGGCGTCAAACAGCGTCTgtctaaaaaattattcaatgacGCTGATGACGCCAATAGgcgtcataaaaaaaaaggtggATCTTTGAGCAGAActgaagaaaacaaaattaaaaccgaaataaaaatcgaaaaaaatgttGTCGACAGTTTTGAATTTGAAGGAACAGTTTTTGAGGAAAATAATACTGCAGAACTTATTAATCGGATGAATTTGGACAAGACATCTAGATCTAACTTAAGAAAAAAAGaattcatttgttttatttgtaataaatcatttaattataaatcaccATTGAAAAAACATATACTCCTTCATTCCAGAAAAGAACTTTACAATAGCacggtttataataaaaaacataataagtatttaaaaccaAACTTGAAAATGCACATAAGTGATAAacctattaaatgtaatatctgTGATCGAACGTTTTCATcgagattttatttaataagtcaCACAATGACACACGCCGGAGAAAAACCATTCATATGTGGTATCTGTGGTCAAGCGTTTCCTCAATCACGTTCTTTAAAAAGACACTCAAGGATACACACAGGAGATAAACCATTCAAATGTGATATCTGTGGGCATGCGTTTTTTCAATCATCAGATTTATCAATACATACAAGGACACATACTGGAGAAAAACCATTCAAATGTGATATATGTGATCGAGCGTTTTCTCAATCACAATCTTTAAAAAGACACACGAGGACACACACTGGAGAAAAGCCATTCATATGTGATATCTGTGGTCGAGCGTATTCTCAatcaacacatttaaaaaatcatacgAGGAAATATCATGGGGAAAAAGCCAAATAA
Protein Sequence: MTPNGVKQRLSKKLFNDADDANRRHKKKGGSLSRTEENKIKTEIKIEKNVVDSFEFEGTVFEENNTAELINRMNLDKTSRSNLRKKEFICFICNKSFNYKSPLKKHILLHSRKELYNSTVYNKKHNKYLKPNLKMHISDKPIKCNICDRTFSSRFYLISHTMTHAGEKPFICGICGQAFPQSRSLKRHSRIHTGDKPFKCDICGHAFFQSSDLSIHTRTHTGEKPFKCDICDRAFSQSQSLKRHTRTHTGEKPFICDICGRAYSQSTHLKNHTRKYHGEKAK

Sequence clustering based on sequence similarity using MMseqs2