Alep022384.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Acronicta leporina
Gene Symbol
gprs
Assembly
GCA_947256265.1
Location
OX366524.1:5063564-5078644[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 4.5e-09 1.4e-06 28.8 0.0 9 45 51 88 44 104 0.85
2 2 2.1e-11 6.7e-09 36.3 0.0 44 106 135 197 122 200 0.82

Sequence Information

Coding Sequence
ATGGACATCACTATTACTAGACACTTCAGTTTGGATGAATCGTCAATGCGAAGCGGGGCGCTAGCGGCGATGGAGGCCGAGCCCGACCTCAGCACCTTCGAGAACAAGTCAGGGTTGGCAGAGGACATGAAGTTCCTCGCCTCCATGCCCGAGCTGTGTGACGTCACGTTCCTGGTGGGCGATACCAGGGAGCCAGTATGTGCTGTCAAAGCTGTGTTGGCTGCTAGGAGCAGAGTATTTCAAAAGATGCTCTATCAAGCTCCAAGCCCTCAACGCAAGAAGGAGCCAGCGCCTAGGGAGAACAAGCTACGGCTATTCTTAAAAAGATCTTCGGAGCCTCTACTGAATCTCCAAAACGCCGCACAACAGAGATCGACTTTCGCGCAGCAATTGGCACCAATACAAGAGCCATCTTCGCAACAGCATCAGACACTGATCATAGAAGAATTTGAACCCGACGTCTTTCGTCAACTGATTGAATATATTCACACTGGTTGTGTGACTCTGCAACCGAGGACATTACTAGGTGTAATGAACGCGGCTGACTACTACGGACTGGACGAGCTTCGCCGCGCGTGCGCCGGTTTCGTGCAATGCTGCATCACTGTGGACACAGTCTGTGCGCTTCTTGCGTCTGCTGAAAGATACATCCAGTACAAATGCACCAAGTCGTTGGTACAGAAGGTTTTGGAGTTCGTAGATGAACATGGCAATGAAGTTCTGAACCTTGGATCATTCACACTACTGCCCCAGCATGTGGTCAGGCTAATACTAGCGAGAGATGAGCTAAGAGCCGACGAGTTCACCAAGTTTCAGGCTGCGCTGATGTGGAGCAAGAAGTATTGCGACACCAATCAGAATATGATCCTGAAGGAGGTGATTGGCAATTTTCTGGAGTACATCCAGTTCCACAAGATCCCGGCTAATGTTCTGATGAGGGAGGTCCACCCGCTCGGGCTGGTGCCTTACTCTATCATAATGAACGCGCTCGCATACCAGGCAGACCCGGCCAGCGTAGATCCAGGCAAACTCTCCCCGGCGCGAGTCCGACGTGCCGGCCGCTCTATGTCCGTGCAGTCTTCACTTGACCCCTACGGATCCAACACCACCCTCTCCTCTACCGGCTCGAGCGATGTTCCGTCGTCAGACTCTCGGCACAACTAA
Protein Sequence
MDITITRHFSLDESSMRSGALAAMEAEPDLSTFENKSGLAEDMKFLASMPELCDVTFLVGDTREPVCAVKAVLAARSRVFQKMLYQAPSPQRKKEPAPRENKLRLFLKRSSEPLLNLQNAAQQRSTFAQQLAPIQEPSSQQHQTLIIEEFEPDVFRQLIEYIHTGCVTLQPRTLLGVMNAADYYGLDELRRACAGFVQCCITVDTVCALLASAERYIQYKCTKSLVQKVLEFVDEHGNEVLNLGSFTLLPQHVVRLILARDELRADEFTKFQAALMWSKKYCDTNQNMILKEVIGNFLEYIQFHKIPANVLMREVHPLGLVPYSIIMNALAYQADPASVDPGKLSPARVRRAGRSMSVQSSLDPYGSNTTLSSTGSSDVPSSDSRHN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01159553;
90% Identity
iTF_00001318; iTF_00908074; iTF_00301356; iTF_00449333; iTF_00622993; iTF_00114229; iTF_00373275; iTF_00410465; iTF_01246081; iTF_01385954; iTF_00022951; iTF_01134957; iTF_01388656; iTF_00659569; iTF_00412660; iTF_00656277; iTF_00342358; iTF_01463446; iTF_01386877; iTF_00952001; iTF_01159553; iTF_01438177; iTF_01144674; iTF_01157987; iTF_01430083; iTF_01140324; iTF_01130149; iTF_01179621; iTF_01359014; iTF_01080039; iTF_00428296; iTF_00858728; iTF_00341484; iTF_01279436; iTF_00948047; iTF_01147503; iTF_01141808; iTF_01156784; iTF_00075698; iTF_00197490; iTF_01125618; iTF_00076723; iTF_00971507; iTF_01010547; iTF_01142515; iTF_00840404; iTF_00970549; iTF_01082613; iTF_01115829; iTF_00212694; iTF_00365078; iTF_00408598; iTF_01073750; iTF_00622135; iTF_01148951; iTF_01341463; iTF_00889401; iTF_01141049; iTF_01282521; iTF_01180444; iTF_00279262; iTF_00819326; iTF_00429184; iTF_01149729; iTF_01124739; iTF_01359909; iTF_01453409; iTF_01451652; iTF_01452502; iTF_00403970; iTF_00933988; iTF_00934966; iTF_01248344; iTF_00209028; iTF_00638788; iTF_00699394; iTF_01529349; iTF_00662375; iTF_00663239; iTF_00701223; iTF_01219911; iTF_00321736; iTF_01429192; iTF_00704170; iTF_01528461; iTF_00700271; iTF_01183057; iTF_00697522; iTF_01170743; iTF_00706200; iTF_00811193; iTF_01071769; iTF_01171609; iTF_00267354; iTF_00696603; iTF_00703164; iTF_00698461; iTF_00737631; iTF_00119744; iTF_01090948; iTF_00744901; iTF_00837733; iTF_00161702; iTF_00818473; iTF_00000481; iTF_00649281; iTF_00925889; iTF_00290850; iTF_00374370; iTF_00673634; iTF_00786946; iTF_01095106; iTF_00012163; iTF_00783683; iTF_00839555; iTF_01492163; iTF_00806884; iTF_00935876; iTF_00650181; iTF_00785349; iTF_01062981; iTF_01093285; iTF_00033062; iTF_00249830; iTF_00709414; iTF_01363270; iTF_01416998; iTF_00115080; iTF_00206248; iTF_01152328; iTF_00007273; iTF_00063753; iTF_00686505; iTF_01092201; iTF_00120682; iTF_00180618; iTF_00356458; iTF_00761834; iTF_00772170; iTF_01336074; iTF_00666667; iTF_01084427; iTF_01494443; iTF_00406892; iTF_00467532; iTF_00683500; iTF_00888428; iTF_01425260; iTF_00156397; iTF_00407725; iTF_00685613; iTF_00809325; iTF_01317453; iTF_01361805; iTF_01416045; iTF_00008175; iTF_00018319; iTF_00055599; iTF_00072975; iTF_00327216; iTF_00383856; iTF_00657360; iTF_00790448; iTF_01285712; iTF_00187313; iTF_00468305; iTF_00922993; iTF_01020465; iTF_01260273; iTF_01377649; iTF_01526225; iTF_01302546; iTF_01437234; iTF_01538930; iTF_00282579; iTF_00462547; iTF_00835763; iTF_00050100; iTF_00146580; iTF_00632916; iTF_00827156; iTF_01205044; iTF_01220788; iTF_01064821; iTF_01444053; iTF_00648278; iTF_00724086; iTF_01026486; iTF_00155447; iTF_01221751; iTF_01251991; iTF_00124440; iTF_00682584; iTF_00758424; iTF_00810264; iTF_00869816; iTF_00968184; iTF_00323641; iTF_00791353; iTF_01135929; iTF_01172537; iTF_01464313; iTF_01495161; iTF_00185466; iTF_00752219; iTF_01280539; iTF_01342363; iTF_00041052; iTF_00186428; iTF_01178780; iTF_00044669; iTF_00204477; iTF_00928861; iTF_01495901; iTF_01496701; iTF_00195294; iTF_00377246; iTF_00961086; iTF_01030398; iTF_01209470; iTF_01503134; iTF_00878975; iTF_00651904; iTF_00859648; iTF_01569504; iTF_01337861; iTF_00325574; iTF_01316520; iTF_00027019; iTF_01205840; iTF_01487857; iTF_00154642; iTF_00763973; iTF_00318227; iTF_00345971; iTF_00640565; iTF_00705206; iTF_01083510; iTF_01348214; iTF_00710359; iTF_01534104; iTF_00634644; iTF_01562136; iTF_00375481; iTF_00844543; iTF_01337034; iTF_01501322; iTF_00771211; iTF_00822124; iTF_00450321; iTF_01202606; iTF_01509742; iTF_01436272; iTF_00006417; iTF_01081746; iTF_00276602; iTF_00441681; iTF_00909841; iTF_01137041; iTF_01197937; iTF_01502246; iTF_01206709; iTF_00077654; iTF_00235991; iTF_01544087; iTF_01561250; iTF_00707131; iTF_01222620; iTF_01368270; iTF_01545023; iTF_01543103; iTF_00361784; iTF_00208057; iTF_01401441; iTF_00299257; iTF_00815234; iTF_00158189; iTF_00815924; iTF_00799404; iTF_00828090; iTF_00284699; iTF_00358780; iTF_00824028; iTF_00986397; iTF_00419107; iTF_00842820; iTF_00802053; iTF_00842821; iTF_01021445; iTF_01506501; iTF_01507366; iTF_00824903; iTF_00354314; iTF_00205326; iTF_00353294; iTF_00781966; iTF_01017870; iTF_00458192; iTF_00621360; iTF_00461713; iTF_00778129; iTF_00457362; iTF_00774610; iTF_01508210; iTF_00421493; iTF_00695829; iTF_00782773; iTF_00213686; iTF_00723286; iTF_01033879; iTF_01078359; iTF_00247352; iTF_01034744; iTF_00958779; iTF_00777468; iTF_00248253; iTF_00897021; iTF_01080863; iTF_00775392; iTF_00953696; iTF_01018720; iTF_01151349; iTF_00954710; iTF_01079197; iTF_00856798; iTF_00906334; iTF_01016894; iTF_01166879; iTF_00909021; iTF_01387776;
80% Identity
iTF_00001318;