Basic Information

Insect: Acromyrmex charruanus
Gene Symbol: MBD-R2
Assembly: GCA_017607545.1
Location: JAANIC010004487.1:1525800-1535814[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.4e-17 4.3e-14 50.9 0.3 8 69 524 585 518 593 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.4e-17	4.3e-14	50.9	0.3	8	69	524	585	518	593	0.92

Sequence Information

Coding Sequence: ATGGGAATGGCGCGCAAATGCTGCGTTGATAGCTGCAAGACGGACGTGCGGGAGGCGCGCGTCAAAGGATTGCCGCTGCATAAGTTCCCCAAGGACACCGCGCTAAAGGACAGGTGGTTGGCCAGCGGTGGCTTTGAGACGGGTTTCAAGCCGACGCCAGGCCAGGTCGTCTGCCATAGGCATTTTAAACGTGCCGACTACGAGACCGCGCGGGGCGGTCACAAGCTCTTGCTCAAGCGGGGCAGTGTACCCACGATTTTCGCGGACTATGACGATCATCCCGATCCTGTTATCATGTCGGTGAAGTCTTCAACATCGTACGCTCAAGAAGATTTGGATCTGATCAATTCGGAAATACTAAATTTGGAACATTCTGCCTCACCATTATTATCTGAGGCGAGAACACCTAAATCCGACAGTTGCGGTGAAACGTGTTATTCCAGACCTGAGTCGTCAGCAGACTCCTTAAATCTCCCTGATAACTCGGACGTAACAGATAATGaatacaaaatgataaattcaaaagaagaaagaaaaatattcgagACGAATAAACCGAGCAAAAATTCGGATAATAAAGTGAATACAGTAGCGATGCAACTTGGTATCGTCGAGCCAGAAACGGAAATGAAGACTAGTGCCAAAGATCTAATAGCAAAGgaggaattaaaattatctggcAACAAGGAATTCGACAAATCGGAAGAATTGAAACCAAAGGTTTTAAATCGTGgtgatttgaaattttttcctgGTGCCAAATTGGAAGCGAAAGACTTTAATGATAAGTGGCAAGTATCATCAGTGGTAGAAACAGATTGGGACGAGAGGGAAGTTTTAATACACTTTGACAAATGGAGTTCGAGATTTGATGAATGGATACCAATGGACAGTTCCAGACTACGTGTATTGCAAACCCCACAAAACGAACAGGCTTGGATTCCGCCATCTCCGGAAGTGAAGATGAAAGAATTTTCGGTGGGCGAAAGGATACTCGCTACGTGGGCGGATGGCAAAAAATATCCAGCCAAAGTGAGCGCGGTCCTGACGAATGACAGGTATAACGTGCTTTTCGACGATGGATACGCAAAGATCGTCAAGTCGTCGAAAATGACCAAGATCGCTGGAAATTCAAAGCAATTAAGTGAACTGGATGGATATATCGGCAGTAAACAAGAAAGAAGAGATAAGAAAAGGAAACATACAGTTATGGAGTTGTTTAACACTCACTCGAGGAAACGCACGAAACAAGATATCGACAAAACACCAAAAAAGGAGGAGACTGTCGTCAAGGAAAGTGGAGAAACCTCTTCAGAGAACAAGATCGAGATGGATGGTACTCAATACGGTCCTTGTTATGACCCAGGAACAGATTTGTTGAAAGGTTTTGAAACTAATCCCTCAAAAATCAAATCATATTCAAAGAAAAGTAAGAAGGAAGTACCCAAGGTTGAAACGGACCAAATTGAAGAAAACGTTGGTCCTGAATGGATTGATGGAGAACCACAAGGAACAGAATCTTATATTGTAGATGGCAATGATGGGCCTCGCCGATCTATAATAGTACCAGATAAGAGATTGCCTCCTGGTTGGGAAAAACACTTTACACAGAGAAAAGCTGGCTCATCTGCTGGAAAATGGGACGTCTTGTTTATACAtaaacaaaCTGGGAAGAAGTTCAGATCGAGAAATGACATCAGAATATTCATGGAGAATCAAGGACAGTACGACTTTGACCCCGAAAAATTCGACTTCTGTATACATCGCAGAAAACGAAACCACCCGCATCGTGTGAAACAGGAAGTTGCATCGGAAGTTACACCAAAGAAGATCAAAACCTTATTGCCTAAAACAAAAACACCTGAGAATACATTACTTACGACGGTGACGACTAATATCGACACTACACCAGTCACCTCCATGTCTACTACATCTACTACGGATGGTGCTGTTTTTATTGGACTTCGTGGTGGACTTCGTGTAGAAATGGAAGACAGCGCTTATAAATGTCCCAAAGAAggatgcaataaaaattttcgaaaagaaaatttgctGCAAATGCATATCAAACATTATCATCCTGAATATTCCAAATTTCTGGGCTCTACTCCAAAAGTTGAAGATTTAGCTTATGCAAGAACGATCGGGGAATCTATAGAAGATATAATTCCCAAAAAACCGACATTCATggagaaaatgaataaatctgCGAAAAAGAAATCTCTTCCTGAAAAATCGCCATCTACTTTATTGCAATCAACATTAAATACTATGCAACCAACATCTCCGTCAATACCTGGTCCAGTGATGCCAGAAGAAGAGGAAATGGATCAATTAACAAAGTGTAATGATTCGCAGAAGGAGgatatgaaaattgaaacaatgtCACCTATATCTAATCACAGTACGGAGATAGATgaagatattgaaaagaaaagggAGAATGTCTGTGCATTGTCTCCTGGTACATTATTTGACATGaaagtaaaagaagaaaaagcgCAAGGTGGCATTAAAACTCTGTTGCCTGTAAGACCAGTCGCAGCATCGGAGGTGCAAAGGACCGATAGGACAAAACCTCTGGATGATATGACGCACGTTGAACGCgcaaaaaatcagaaaaaaaggCTTACCGAACACAATGTGGATTTGTCAGTTAAAACAAAGAAGCGACATGATCTTACCGATAGTTTCGGTGATCTAGACGACAGTGCTATGGACGTCGAAGGACCTACGGCACTTATGTATAGATATAGCCGTAGAAAATCCGATTCAAAGAGCGACGAAAATAGCCAGAATAGTCAACTAAATGATTCACGCATTGATAAAGCTGATCCCCTAAAAGGGGATGCAATCAAaacagatattaataatgatgcaGAAGAAAGTGAAGGAGTGATGATGATGATCAATGGCGAACTGGTAAAAGTAGAACAGCTTCGAagagaagaaataataaattgcacGTGTGGCTTTATGGAAGAGGACGGTTTGATGATACAGTGCGATCTCTGTCTCTGCTGGCAACATGGTCAttgtaatttcattgaaaaggAAAAGGATGTTcctgaaaaatacatttgttaCATATGCCGAAATCCACATCGACAACGGCCttctaagaaatattttcatgatcaGGACTGGATTAAGGAAGGAAAATTGCCAAGTTTACCTAATCGAACTCGAAATCAGTATATGATCAATCAAAGGACTGCAATGTTGAAGCGTTCTTATGACTTAGTTGCTGCACTTTTACAAATTCAACAACTTCTTCATAGTTTGCGTGTAAAAATCAACGTAGCACAaAAGAAAGATCATCCGAAACTATATCTTTGGGCCAAGAATTGGGAGAAAATGGATATGTCAAAAATAGATATGGAACCAGTACCAGTAATGGAAATAACTAAAGCGGCAAGTTTTACTAATACAGGTTCGGAAATTCCGCGACGTGTCGAGACAAAGACTGATATCAAGTTGTCAAAGGATGATCAAGATGAAAAATCGATCGCTTCTGATTCGgaattgatgaaaattttggAAGAGGATAGCACACATTCTGATGAATCCAGGATTATCAAGAAGGAAGGCTTGATGAATTCGAAAGACAGCCATATACTTTTAGACGCATTAACGAGTAGTAATTCAGACATAAAAGAAAAGGACATTACTACGTCAGACATTAAAGCGGAAGAAGCAGATTTGTTAGCTGACAAAACTATTGCTAATCCTGTACCTGAGAATCTTAATTCTGGATCGCTTATTATCGACAACGTACAACAAGAAACTAGTATAACTGTCGAGAATGAAGTCTCCGCACTTCCGCAGCCTTTTATACCAGAGCCCGAAGCACCGATTGATCCAGCCGAATGCCGAATGCGATTGTTGGAACATATTGAGCATTTTCAATGTCATATTGATTCGAGATTAACATCCATAGAAACGCAAATTTTTgCTCTAGAGGCAATGGACCCGGATGAACTTGTATCAGATCCGCTTGTACAACCTCGTACTAAGCAGACGGTCCAGATGCTCCTTCGTGACTTGAACACAGTCCGAAAATTGGCAGCATTATGT
Protein Sequence: MGMARKCCVDSCKTDVREARVKGLPLHKFPKDTALKDRWLASGGFETGFKPTPGQVVCHRHFKRADYETARGGHKLLLKRGSVPTIFADYDDHPDPVIMSVKSSTSYAQEDLDLINSEILNLEHSASPLLSEARTPKSDSCGETCYSRPESSADSLNLPDNSDVTDNEYKMINSKEERKIFETNKPSKNSDNKVNTVAMQLGIVEPETEMKTSAKDLIAKEELKLSGNKEFDKSEELKPKVLNRGDLKFFPGAKLEAKDFNDKWQVSSVVETDWDEREVLIHFDKWSSRFDEWIPMDSSRLRVLQTPQNEQAWIPPSPEVKMKEFSVGERILATWADGKKYPAKVSAVLTNDRYNVLFDDGYAKIVKSSKMTKIAGNSKQLSELDGYIGSKQERRDKKRKHTVMELFNTHSRKRTKQDIDKTPKKEETVVKESGETSSENKIEMDGTQYGPCYDPGTDLLKGFETNPSKIKSYSKKSKKEVPKVETDQIEENVGPEWIDGEPQGTESYIVDGNDGPRRSIIVPDKRLPPGWEKHFTQRKAGSSAGKWDVLFIHKQTGKKFRSRNDIRIFMENQGQYDFDPEKFDFCIHRRKRNHPHRVKQEVASEVTPKKIKTLLPKTKTPENTLLTTVTTNIDTTPVTSMSTTSTTDGAVFIGLRGGLRVEMEDSAYKCPKEGCNKNFRKENLLQMHIKHYHPEYSKFLGSTPKVEDLAYARTIGESIEDIIPKKPTFMEKMNKSAKKKSLPEKSPSTLLQSTLNTMQPTSPSIPGPVMPEEEEMDQLTKCNDSQKEDMKIETMSPISNHSTEIDEDIEKKRENVCALSPGTLFDMKVKEEKAQGGIKTLLPVRPVAASEVQRTDRTKPLDDMTHVERAKNQKKRLTEHNVDLSVKTKKRHDLTDSFGDLDDSAMDVEGPTALMYRYSRRKSDSKSDENSQNSQLNDSRIDKADPLKGDAIKTDINNDAEESEGVMMMINGELVKVEQLRREEIINCTCGFMEEDGLMIQCDLCLCWQHGHCNFIEKEKDVPEKYICYICRNPHRQRPSKKYFHDQDWIKEGKLPSLPNRTRNQYMINQRTAMLKRSYDLVAALLQIQQLLHSLRVKINVAQKKDHPKLYLWAKNWEKMDMSKIDMEPVPVMEITKAASFTNTGSEIPRRVETKTDIKLSKDDQDEKSIASDSELMKILEEDSTHSDESRIIKKEGLMNSKDSHILLDALTSSNSDIKEKDITTSDIKAEEADLLADKTIANPVPENLNSGSLIIDNVQQETSITVENEVSALPQPFIPEPEAPIDPAECRMRLLEHIEHFQCHIDSRLTSIETQIFALEAMDPDELVSDPLVQPRTKQTVQMLLRDLNTVRKLAALC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00730116;
90% Identity: iTF_00014768; iTF_00181961; iTF_00181352; iTF_00181302; iTF_00182011; iTF_01476917; iTF_01476969; iTF_00015419; iTF_00015369; iTF_01476171; iTF_00016079; iTF_00016036; iTF_01261874; iTF_01261831; iTF_00016725; iTF_00016680; iTF_00417557; iTF_00417637; iTF_01477563; iTF_01477644; iTF_00182620;
80% Identity: iTF_00014768;