Acon031717.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Acrobasis consociella
Gene Symbol
egg
Assembly
GCA_963555685.1
Location
OY743134.1:4796928-4843241[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.9 1.2e+04 -3.0 0.1 28 38 1676 1697 1663 1698 0.64
2 2 2.8e-13 1.7e-09 38.1 0.0 4 74 1729 1792 1726 1795 0.88

Sequence Information

Coding Sequence
atgAGTTCCACAGAGCAGGAGCTACCTTCCACCAATGACAAACCCAATTCCCCATCACCACCTACAGACACCACAGCTGAGTCAAAACCTGATGAGGATCATAAAGACTGTGGAGATGTAGAAATACAGAAAATTGATGATGATATTACTAAAACTGTTGAGTCTAAACATACTGAAGATACAACTAGCAATTTGCctccaaatcaagttgaaattGATAAAAACTTCgaatttgatgatgatgatgatgatgacgattttAACAGTGACGACATGCATTTGAAAtgggaagatgatgatgatgagacaatCAATAATGATAAATCTAAAGACTCTGAATCAAATAATCCATCAACTTCATTAGTTACTGCTGTAAAAGACTTAGAAAATGCTCTTAAAGAAACCACCAATTTTAATCCTAATGTTGAAAGCTCTATTAAAGAGAATGAAGCTGGTAAAGACGTTTTAGAAGAACCTGAAAGTAGTTCATCTAAAGAGATTTTAGATGATATTGATAAGCTTATTGGAAATGATGAAACAACTGAtgtaaataaagaagaaagtttACAAAAGAATTCTAAGAAAATCGGTGGATCGggagaaaaaattaaagatcCTGTAGTTAGCATTGATGAACCCAAATCAAATGTTAGTAATCAAATAGAGGAAAGTACTCCAATTAGTTCAACAAAAGATGAGACTAAGAGTGAAGCTGATTGCATCAATCTAGATGACTCTACTGAAAGTGTTGAAATGATAAATGAAAGTAGCCTCCTTTCAAGCACAGTAAATTATTCCATTGTAGAAGGAAACACTAAGTTTGAACATGGACTTAAAAGGCCGGACGTGATGTTGGAGATACCGACCCAAGAATTAATCGACTGTTTGGATGACTTTGACTCAGACAATGAAAAAAGTGATGAAAAAGTTCAAAGTATTGATGTtagtaaacaaattaatagtTTAGAAGAAGATATTGATTCGAAGGCATTAGATAATGAGATAGGAAGAATCGATCAAGAATTGACTGAGAATATTTCAGCTTTAACTGAAAAAAGTCTAGATGTAGATGAAAAAGTTGAAGGTGAAGAAAACACTGCATCCAAAACAGAGGGCAGTGAAATGGAAATTATTGTCCAACAAATTGTTGACAACATCCCAATTGTGACTGAAATAAATGAAGGTATTGCAGAACAAACAAATAGTGTAAAAGCAAACAATGAAGCAAAAATACTTGACAATGAGATAGAAATGATAGATAAACAAATATCAGACAGTATTCCTGATTCTACAACAAAAGATGAAGGCCTTGAAATGAGCGACGATATGTCTATGACTAAAAAGGAACAAGattctaaaaatgtaattaatgatGTAGAAATGTGTGATGTTTCtgaattagtaaataaaattgaaaaagatGTCAAATCGCAAACGTTAGAGGCAGAAAACAAGGCTGAAATAATGCCAGAACTTGTTAAGCTTTCACCAAGTGATGTACCTAAAGGTACACCTATAGTAGACACTCCAATGGAAGTGGAAGAAACTAATACTTCTGAAAAAGTTACTTCTCAAGAACAGTTCACCTCTCTACCACAAACAAATAAAGATTTAGAAAAAGACCAGATACCCATAAAATCATCAATTGAAACCAAACACACAgaccaagaaaaaaatattaaacaaagtGATGAAAAAGTTAATAAGAAAACATCAGAGCAAGAAAATACCACAACACACGACATCAAAGAATCATGTAATTTACAACCTACTTCCTCTGAGGCTTTAGAATCTGTTGCCATAGAAACCTTAGACAAAATTGATGAAAAAATCATAGTGACAACTACTAATGAAACAGCGATAACTAATTTAGAAACAGCAATTTCGGATACAGAATCAGACATAAACGATACATCAACCATtgacaaacaaaaagaaaatgtagATGTACCAACCATACCAGTATTGGAACAGAAGTCAGGCTTAGACCAACCATCAAAAGAGTCTACTGTGTCTGATAATATAGAACCAATACCTACACCAACAGTAGAGCAAAAAATTGAAAGTGAACATCCTACAGATGATTCAGAAAATAAAGATGCAACAGACGTACAAACATTGAAACAACCATCAACAGATTTagatattaaagaaaattcagAAATATCAGTGTTGTCAGAAAAAGTTAAAGATTCTGAATCAGATATTATACCAGAAATAGCAGAAATATCTGCATCCAAAGATGATATCAATTCAGTTGATGCAGAACCAAAACTTTCACCAATGTTAGACCAACCATGTACATCTAAAGATGTAGTAAATACAGTACATGAAGAGCCCAAAACTACACCCGTATTGGACCAATGTAAAGAAGCCACAGTTGATTCTTCCATAGCACCAACAACACCGTTATTAGATCAACCTTCTACATCCAAAACAGAATCAGACAATTCTGTAGGCAAAGAAGCATTGGACAAAAAAGATGAACTTCAGGGTCAAATACCTGATACGACGGATGAAGTGCCAGAGATGGAAGACACTTTGGGGCTGTTGGCGGAGTCCTCCAGGGTGGTGGAAGACGCTGAGGGTAGTAGTGAAGGTGGTGATGCTGAAGAAGACGAAGAAGGTGATGAGGATGATGACTTTGATCCTGATGATGAGAGCAGCAACCAAATGACAGCAGAGCACTCAGAAGAATCAAACACGCTACCCGAAAAAGAAGACGCACAGACGGATAAAGAAGACAAAACTCCGGAGCAGGAGAAAGACTGCAACTTAGCTATAGCTCCTGTCACTGCGGAGGATGAAACAAAGGGTGTTGATATGGAAGTGACTTCCGGGGACTCCAAGGTCCCCAATGACGGTGCAATACCTGAAGAGGTCACTGCTGCAACAGACTCCACTACTGAAGTGAAGGCCAATGATTCTGAGAACAAGGAGacTGCAGTCACAAAAGAGATAGAAACAGTCAAGTTGTCGGACACGTCTGACAACGAAACGGATATAGCTACTAGTATCCTGAAGGAACTGTTGTTGACTGAAGCAAAACCTCCGATGGTGAAAACTGAAGCTTCAACTGACACTGGTGTGGTGGATGTCGAAAGCTCATCAGAAGACGATGTTCAAGAGATAAGCAAGAAGAAAACTGAAGAAGAGAATGTTGTCAAAGAAGAGGAGACAAAATCGCAGCAGGAAGACTCAAAAACGGAAGAAGCGGAAATTACTTCAGAGAAAATTGATAATCTACCAAAAATCGTTGAGGCCAAATCGGAGTCGACGAAGCCCGAGGCTGCCGCGAGTTCGGAAGTGTTCAACCTGGACTCTGATGACGAAGACGTGCCCAGTTTAGCTAACGAAATAGTTATCGAGGAGAAACTGGAGTCGAACAAGTGCATCAACCCCGCTTGTCGCAGCGGCGCGAACGCTACGTACGTGGTGGCTGACGTGGCGGCTAGGGCTTACTTTGACGCGAACAAGAACAAGAAGTACAGGGTGTGCTTGGCCTGCGCCGACGCGGTGGTCGAGAGGACCAAGGGATTGGTAAACGGAATCAAGGGAATGACTCCTTTACTGGAGCTGGACCTTCGAAAGGTCTCGTCCGAGACTGTGGAGATCTCTGACTCGGACTCGGAAGACGGGGAGACAGACAGCGTGAAGCCAGAAATCATTGGGGAGAGCGGTGCAAAGTTTTTGGAGGAACATTTGGCTGACGTGATCAACGAGACGTGGATCAAGTACAAGCTGGACGAGCGGCTCGGCTATGCCCAGAGCGAGCTCGACGATGAGCTGGCAAAGCTGGAagCGGAGAGCAAAGAGATCGATACGATGCTATCGGAGTGCCAGGTGGCGACGGACCTGCTGCGGAACCAGCTGTACGCCTCCTTCGAGCCGGAGCGGCGCGAGCTCTCGGCCATTTGCATCATCGATACGCCCAACGAGAAATTTTCCCAGATTCGCTTGAAGCGCAAGTCGACCGCCGCCAGCGAGCAGCCCGCCAAGAAGCCCGCCATCCCGCTGGGGTACGCGCCGATAGAGGCGGACGGCGCAGACAAgGACTCTAAGCAACCTAAGGAAGATAGTACTGCTGATGACgatAAGGACGTGTCAGTCGTAAAGTTGTCAGCGGAAGCGGCGCCCTCAGACCTGCCTCCGCCAGGGGAGATATCACGTCCTCAGCTGCGGCCGGGCATGTCAGTGTTCGCTATGAGGAACTCATTCTGCACCTGGGTGCCGGGGAAGATAATAGACGTGCATCCTAAGAACCCAGCCAATCCGTTCACAATGTGCCGCGTGCGATTCGAAATCCGAACAAAGATCGCGACGCGTTTGCTCGCCGCTAGATGTCTCGCCTACCTCGAGCCTGCTGACGTCAGACTGACTATCGGTACTCGCGTCATAGCGCTGTCAAAAGAGAACGCGAAGATGGATGAGCCCGCCAAAAAGAAGAGTTTCTACTCGGGAATAGTCGCTGAGATCCCGAACCCTGTCAACAACTACAGGTACCTAATCTTCTTCGACCACGGTTACGCGCAATACGTCCAACACCGCGAAACCCGCGTGGTCTGCGAGAGTGCCAACCTTGTGTGGGAGGAAGTACACCCCAATTCGCGGGAGTTCGTCAAGCAGTATCTATTGGCGTATCCAGAGCGGCCCATGGTGCGCCTGCATGCTGGACAGAGCCTGAAAACAGAGTGGAACGGAAAATGGTGGGTGACCAAGGTGCTACAAGTGGACGCTTCCCTGGTGGAGGTTTCCTTCGAGGACAACCGGTCGGAGTGGATCTACCGCGGCTCCACCAGACTGGCGCCGCTGTTCCTGGAGCTGCAGGCGGCTGAGCGGCAGCGGGCCCGGCCTCTGCCCAGGAGTAACCAGAGGAGGATGAACATGCCGTACGTGGAGTACACGCGGTCAGAAGAGCAGAACAAGGCGGAGGCGCTCGCGGCGGACCAGGCAaggcagcagcagcagcagcatgAGGAGTTGCGCCGGCAGCGCGCGGTGGCCAAGAAGTCGACggctgcgcccgcgccgcccgcgccgacCGCGCCCAACCTCGACAGCGTCACCAGCCGGGTCGTGTACTACACGCCGAAGAACGCAGTGAAGCCCCACAAGATGTCGCCACACACGTGCTCTCCCAAATGCAAACGCACGGACACTCTAGCGCTCAAAGATCTCAGGACGTACAACCCGCTGGCTAAACCACTGCTCAGCGGGTGGGAAAGACAAATCGTTCGCTTCAAAGGCCACAAAGAGGTCATGTACCGCGCCCCGTGCGGTCGCCGGCTGAGAAACGTGCAGGAGTTACATCGGTACTTACGAACCGTACAGTCCGATATGGGAGTCGACCTGTTCGACTTTGGTGCGAATACTCATTGCTTGGCCGAGTTTGTGTTGAACAAGTGTCTAGTGGGCAAAAAGGATTTGTCCCACGGCAAAGAGAATGTCCCAGTCCCATGCGTGAACTACTATGACGAGTCGCTGCCAGAGTTTTGTTCCTACAACACCGAGAGGACGCCCACCGCTGGGGTCCCACTCAATCTAGACCCAGAGTTCCTGTGCGGCTGTGACTGTACCGATGACTGTGAGgacaAGACAAAATGCGCGTGTTGGAAGATGACGCTAGAGGGCGCCCGGACCATAGGCCTGCAAGGGCCCAACATTGGGTACGAGTACAAGAGACTGCAAGAGCCACTGCCTTCCGGAATTTACGAGTGTAATTCTAGGTGTAAATGCAAGCATACCTGTCTCAATCGAGTTGCGCAACACCCACTGCAGCTTAAGTTACAGGTGTTCAAGACGATGAACCGCGGCTGGGGCATCCGCGCGCTGAACGACGTGCCCAAGGGGTCGTTCCTGTGCGTGTACGCGGGGAACCTGCTCACCGACGCCACCGCCAACCTGGACGGGCTCAACGAAGGTGACGAGTACCTGGCAGAGCTTGACTACATCGAGGTTGTGGAGCAAATGAAGGAGGGCTACGAGGAAGACATCCCGGAGGCCGACAAGAAGTTAGACCGGAAATCATCTAAATCATCATCGGAGGAGGAGGAATCGTCGTCAGAAGAGGAGAGCACGAATAAGAACGACAAGATGGACGACGACTTCCAGCCGGGCTCTATCGGACTAGGGCTTACTGAATTCAACAAACGCTTGCGGAAAAGAGACAGGACGAGAAGAAGAGATGCAGAGAAGCAGAAAGGGAAGGAGATAGACAAGGGTATGGAAGATGACGGCTGCATCACCATCAGTGATGACGAAGAAGCAAAAGAGCCGACTCGGTTCATGGCACAGGCCAACATTGGCGGAAACGAGTTTGTACCTAAATATAGGTCTGTGCGTACATTATTCGGCAAGGACGAGGCTTGCTACATCATGGACGCGAAGGTCCAGGGCAACATCGGCAGATACCTCAACCACTCGTGCACGCCCAACGTGTTCGTGCAGAACGTGTTCGTGGACACGCACGACCCGCGCTTCCCGTGGGTCGCGTTCTTCGCGCTGGCGCACGTGCGCGCCGGCTCCGAGCTCACGTGGAACTACAACTACGACGTGGGCTCCGTGCCCGGCAAGGTGCTGTACTGCTACTGCGGCGCGCCCAACTGCCGCGGCCGGCTGCTCTAA
Protein Sequence
MSSTEQELPSTNDKPNSPSPPTDTTAESKPDEDHKDCGDVEIQKIDDDITKTVESKHTEDTTSNLPPNQVEIDKNFEFDDDDDDDDFNSDDMHLKWEDDDDETINNDKSKDSESNNPSTSLVTAVKDLENALKETTNFNPNVESSIKENEAGKDVLEEPESSSSKEILDDIDKLIGNDETTDVNKEESLQKNSKKIGGSGEKIKDPVVSIDEPKSNVSNQIEESTPISSTKDETKSEADCINLDDSTESVEMINESSLLSSTVNYSIVEGNTKFEHGLKRPDVMLEIPTQELIDCLDDFDSDNEKSDEKVQSIDVSKQINSLEEDIDSKALDNEIGRIDQELTENISALTEKSLDVDEKVEGEENTASKTEGSEMEIIVQQIVDNIPIVTEINEGIAEQTNSVKANNEAKILDNEIEMIDKQISDSIPDSTTKDEGLEMSDDMSMTKKEQDSKNVINDVEMCDVSELVNKIEKDVKSQTLEAENKAEIMPELVKLSPSDVPKGTPIVDTPMEVEETNTSEKVTSQEQFTSLPQTNKDLEKDQIPIKSSIETKHTDQEKNIKQSDEKVNKKTSEQENTTTHDIKESCNLQPTSSEALESVAIETLDKIDEKIIVTTTNETAITNLETAISDTESDINDTSTIDKQKENVDVPTIPVLEQKSGLDQPSKESTVSDNIEPIPTPTVEQKIESEHPTDDSENKDATDVQTLKQPSTDLDIKENSEISVLSEKVKDSESDIIPEIAEISASKDDINSVDAEPKLSPMLDQPCTSKDVVNTVHEEPKTTPVLDQCKEATVDSSIAPTTPLLDQPSTSKTESDNSVGKEALDKKDELQGQIPDTTDEVPEMEDTLGLLAESSRVVEDAEGSSEGGDAEEDEEGDEDDDFDPDDESSNQMTAEHSEESNTLPEKEDAQTDKEDKTPEQEKDCNLAIAPVTAEDETKGVDMEVTSGDSKVPNDGAIPEEVTAATDSTTEVKANDSENKETAVTKEIETVKLSDTSDNETDIATSILKELLLTEAKPPMVKTEASTDTGVVDVESSSEDDVQEISKKKTEEENVVKEEETKSQQEDSKTEEAEITSEKIDNLPKIVEAKSESTKPEAAASSEVFNLDSDDEDVPSLANEIVIEEKLESNKCINPACRSGANATYVVADVAARAYFDANKNKKYRVCLACADAVVERTKGLVNGIKGMTPLLELDLRKVSSETVEISDSDSEDGETDSVKPEIIGESGAKFLEEHLADVINETWIKYKLDERLGYAQSELDDELAKLEAESKEIDTMLSECQVATDLLRNQLYASFEPERRELSAICIIDTPNEKFSQIRLKRKSTAASEQPAKKPAIPLGYAPIEADGADKDSKQPKEDSTADDDKDVSVVKLSAEAAPSDLPPPGEISRPQLRPGMSVFAMRNSFCTWVPGKIIDVHPKNPANPFTMCRVRFEIRTKIATRLLAARCLAYLEPADVRLTIGTRVIALSKENAKMDEPAKKKSFYSGIVAEIPNPVNNYRYLIFFDHGYAQYVQHRETRVVCESANLVWEEVHPNSREFVKQYLLAYPERPMVRLHAGQSLKTEWNGKWWVTKVLQVDASLVEVSFEDNRSEWIYRGSTRLAPLFLELQAAERQRARPLPRSNQRRMNMPYVEYTRSEEQNKAEALAADQARQQQQQHEELRRQRAVAKKSTAAPAPPAPTAPNLDSVTSRVVYYTPKNAVKPHKMSPHTCSPKCKRTDTLALKDLRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNVQELHRYLRTVQSDMGVDLFDFGANTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDESLPEFCSYNTERTPTAGVPLNLDPEFLCGCDCTDDCEDKTKCACWKMTLEGARTIGLQGPNIGYEYKRLQEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTMNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDRKSSKSSSEEEESSSEEESTNKNDKMDDDFQPGSIGLGLTEFNKRLRKRDRTRRRDAEKQKGKEIDKGMEDDGCITISDDEEAKEPTRFMAQANIGGNEFVPKYRSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCTPNVFVQNVFVDTHDPRFPWVAFFALAHVRAGSELTWNYNYDVGSVPGKVLYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-