Basic Information

Insect: Acraspis erinacei
Gene Symbol: ZFX
Assembly: GCA_035041075.1
Location: JAWWLR010000004.1:70904628-70906310[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3 1.2e+03 2.7 2.7 1 23 72 95 72 95 0.81

2 14 2.5e-05 0.01 18.6 0.3 3 23 177 198 175 198 0.96

3 14 0.002 0.81 12.6 0.1 2 23 211 232 211 232 0.98

4 14 4.2e-05 0.017 18.0 1.9 2 23 235 256 234 256 0.96

5 14 0.0058 2.3 11.2 0.3 1 23 262 284 262 284 0.95

6 14 9.9e-06 0.0039 19.9 4.5 2 23 291 312 290 313 0.95

7 14 0.044 18 8.4 3.7 5 23 326 344 325 344 0.97

8 14 8.9e-06 0.0035 20.1 1.5 3 23 351 372 350 372 0.97

9 14 0.0041 1.6 11.7 0.3 2 23 388 408 387 408 0.97

10 14 4e-05 0.016 18.0 1.2 1 20 414 433 414 436 0.92

11 14 3.3e-05 0.013 18.3 2.7 1 23 444 466 444 466 0.99

12 14 0.00093 0.37 13.7 3.2 1 23 472 494 472 494 0.97

13 14 1.7e-05 0.0068 19.2 9.8 1 23 500 522 500 522 0.99

14 14 0.0031 1.2 12.1 6.6 1 23 528 550 528 551 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3	1.2e+03	2.7	2.7	1	23	72	95	72	95	0.81
2	14	2.5e-05	0.01	18.6	0.3	3	23	177	198	175	198	0.96
3	14	0.002	0.81	12.6	0.1	2	23	211	232	211	232	0.98
4	14	4.2e-05	0.017	18.0	1.9	2	23	235	256	234	256	0.96
5	14	0.0058	2.3	11.2	0.3	1	23	262	284	262	284	0.95
6	14	9.9e-06	0.0039	19.9	4.5	2	23	291	312	290	313	0.95
7	14	0.044	18	8.4	3.7	5	23	326	344	325	344	0.97
8	14	8.9e-06	0.0035	20.1	1.5	3	23	351	372	350	372	0.97
9	14	0.0041	1.6	11.7	0.3	2	23	388	408	387	408	0.97
10	14	4e-05	0.016	18.0	1.2	1	20	414	433	414	436	0.92
11	14	3.3e-05	0.013	18.3	2.7	1	23	444	466	444	466	0.99
12	14	0.00093	0.37	13.7	3.2	1	23	472	494	472	494	0.97
13	14	1.7e-05	0.0068	19.2	9.8	1	23	500	522	500	522	0.99
14	14	0.0031	1.2	12.1	6.6	1	23	528	550	528	551	0.96

Sequence Information

Coding Sequence: ATGTCTGGTTTTTTATTCTTACAGATTTATATCGGACAAGAAACATCACGTATGTCAACATCATATGATCTTATGGCTCGCGAAACTTGGGATGAATCAGAGGGTTCGGATAATGAGATAGGAGGATCTCTTTTAGATAGCCGATCCTTAGCAACGCATTTTACGTCTAGTCTGTTTTTAGATCGCGATAGAAAGACGCCTACGCGGCGAATTTTCAAGTGCTCATTCTGCACTGAGGTGTTTGAATGTCCCAAGGAACGTAGAGTTCATAGTACAACTGTCCACAAAGATGCTGGTCCTAGTAATAGTAGAGATCCTGCTCACCAGActgaaattaaagatattaaattattGGATGGACGTATGAATATGTTCGAAGACATTTTCGTAGCAGGATTACATGTTCAACAAACATATCATCAACCACTGTTACATCAGCTTCAACCACCACAACAACTAGATGTAggaaaacctgaaaatgataaaaaggtTGATAATTTAAGAATTCCAACCTCAATGGAcattatttgcaatatttgtaaTCAAAGTTTTAATGGTGAAAAGTCGTTACAAGTTCATCAGAGAAGGGTCCATATTAAGGAATCTGTAAAGCGCGTGCGGGAAAATGCTAAGTGCCAGATTTGTAATCAGGAATTTCCTTCAGTTATTTTATTCAATGCgcatttaaaaatccatcctttagAATGCGGTCAGTGTGGTAAATATTTctatagaaaacaaaatttcaaattgcacgTAAAACGCCACCTTGGAATAAAACCCTTTCCATGTTCAGTATGTGACAAAGCTTTTCTTACGAAGCAAAAGCTTGATGAACACACCAATGGACACACTGGTAATGCTCCCGTTAAATGCAATTTATGTAATGAAACTTTTCGAAGATACTCGAACTTAACTCAACATAAAAATAGACATCACTTGCAcgtgaaaaaaaagttaaaggaTTATATATGCCACTGTGGAGAAGTATTTCATACAAAGAAGAAACTCGCATGGCATAAAGAGACACATGATGAAAAACCAAAAGCTTGTACATATTGTAATGAAAGGTTCATTCACATGGCTAGCCTAACTCGTCACATGCGACGTGCTCACAATCGAAGATTTGTTCCTGATGCTCAAAGGGAAAGTGAAAATGTAGAGTGTCCGATATGTAAATGCATTTACTTACGGTCCTCTTTAGCTGTACATATGAGAGTGCATAATGGAGAAAAGCCATATGATTGTCAAGTTTGCTCTAAATCTTTTAGTACGAAATGGAATTTGCAATTACACAAATGGACTCATGCTGCAAGAAGTACTAAACCATTTAAATGCAATCAATGTAGTGCTGCCTTCTACCGACATAGTGACTACACAGCACACATGAATTCTCACAGAAATGTACGGCCTTACACGTGCAATTATTGTGGAGCTCAGTTTATACGAAAATACAATTGTCTCAGGCATGTCAAGGAACACGAAGAAAATAAAGCTTACACATGTCATCACTGTAACAAAACTTTTCATAGATCGTATTACCTCAAAGAACATTTGCGTGTACATACGGGTGCAAAACCATATTCGTGTCATATTTGTGGTAAACTGAGTAGCACTAAATCCAACCATAATAAGCATGTGAGAATTCATCACGCGCGAGAGCCTGTAAATaccgaaaattaa
Protein Sequence: MSGFLFLQIYIGQETSRMSTSYDLMARETWDESEGSDNEIGGSLLDSRSLATHFTSSLFLDRDRKTPTRRIFKCSFCTEVFECPKERRVHSTTVHKDAGPSNSRDPAHQTEIKDIKLLDGRMNMFEDIFVAGLHVQQTYHQPLLHQLQPPQQLDVGKPENDKKVDNLRIPTSMDIICNICNQSFNGEKSLQVHQRRVHIKESVKRVRENAKCQICNQEFPSVILFNAHLKIHPLECGQCGKYFYRKQNFKLHVKRHLGIKPFPCSVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLHVKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGEKPYDCQVCSKSFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCHHCNKTFHRSYYLKEHLRVHTGAKPYSCHICGKLSSTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01389664;
90% Identity: iTF_01389664;
80% Identity: -