Aeri001465.1
Basic Information
- Insect
- Acraspis erinacei
- Gene Symbol
- -
- Assembly
- GCA_035041075.1
- Location
- JAWWLR010000002.1:20538055-20568050[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 3 1.2e+03 2.7 4.7 2 23 366 388 366 388 0.96 2 22 0.016 6.4 9.8 1.5 1 23 469 491 469 491 0.98 3 22 1.1 4.5e+02 4.0 0.5 1 19 498 516 498 516 0.97 4 22 0.0047 1.9 11.5 1.0 1 23 540 562 540 562 0.98 5 22 0.02 8.1 9.5 0.2 1 20 614 633 614 635 0.94 6 22 0.26 1e+02 6.0 2.1 1 23 647 670 647 670 0.93 7 22 0.006 2.4 11.2 1.2 2 23 676 697 675 697 0.95 8 22 0.0015 0.58 13.1 1.0 1 23 730 752 730 752 0.97 9 22 0.00085 0.34 13.8 0.1 1 23 758 780 758 780 0.97 10 22 2.3e-07 9.3e-05 25.0 0.6 2 23 817 839 817 839 0.96 11 22 0.0051 2 11.4 0.2 3 23 847 868 845 868 0.96 12 22 4.1e-05 0.016 18.0 0.2 2 23 876 898 875 898 0.96 13 22 0.0038 1.5 11.8 0.4 1 23 907 929 907 929 0.93 14 22 0.51 2e+02 5.1 0.1 2 19 1006 1023 1005 1024 0.93 15 22 0.076 30 7.7 0.0 2 23 1045 1066 1044 1066 0.96 16 22 0.012 4.7 10.2 1.2 1 23 1082 1104 1082 1104 0.97 17 22 0.00032 0.13 15.2 1.0 2 20 1122 1140 1122 1142 0.93 18 22 0.12 49 7.0 0.7 2 23 1173 1195 1172 1195 0.90 19 22 0.00025 0.1 15.5 0.4 2 23 1221 1243 1220 1243 0.92 20 22 0.0033 1.3 12.0 1.9 1 23 1249 1273 1249 1273 0.95 21 22 0.26 1e+02 6.0 2.0 1 23 1278 1301 1278 1301 0.91 22 22 1.7 6.6e+02 3.5 0.5 2 23 1332 1354 1331 1354 0.93
Sequence Information
- Coding Sequence
- ATGAATGAAATTGAAGAGCTGCAGGGCCTGGAAAGTGCGTGCCGACTTTGTTTAACGACAGATGAAACAAGATCATCCATTTTCGGGACAGCACATTCCGTAGTGCCGTTGACTCAAAAAATACAGAACTGTGTCACTGTTGAGgggagaaGTGCTGTTAAAGAGTGGAGGAGAAGTGGTGTAAAAGAGGAGAGGACAAGTGGTGTAAAAGAGGAGAGGACAGGTGGTGTAAAAGAGGAGAGGACACGTATTGTAAAATATGGGAGAAGTGGCGTAAAAGAGATTTCTCGAGAGGACAAGTTAACTACTTTGATTTGCATAACTTGTGTTAACAAAGTGAACCAATGGCATCAGTACAAACAATTGTGTCTCCAATCTCAGGACAAGTTGAAGGAATGGTTGACCAGGCAGTCCAAAACTTCTTCGGTCGCAACTGTAAAGCAAGAGCCGAGTACTCAAGAAACCGAAGAAGAAAGTCCACAATTATTGCCAGATAAGGATAAAATTCCTGAGGAGACCTCACCACCGCCAGAAGGTCCCAGCGATGAAATTGAAAAGCTTATGGCGGTTGACAGACCTGCTGAAGTTGAAACGCCAGCGGAAATTGAAGCACCTGTCGAAATAGAAGGAGAAACAGATGCAGCTGTTGAGACACCGGTAGAAATAGAGTCTCCCGTGGAAATTGACACACCCGTGGAGATTGACACTTCCGCGGGAGCTGAAACACCTGTGGACATTGAAACTCCCATGGAAGTTGACACAGAAGTCGAGGAGAGAGTCGAGCGTGAAACGAGAGGCAGTGCCAAGAGAAGATTGTCGAAAGAGACGGTCACTGCAGAGAAACGATCAGAGGCTGTCTCGATTAAAATCGAGCCACCAGATGACGAGTCCCAGGAAGTTGTCGACATCGTCACGCCCACGGAGATATTGCTCCGAAATCCGTTGGCTACGCCCGCCAACGGGAAAGAAGACCAGCCGGCGGAGCCCGATTCGACCCAGAAAATCGTGCCACTCTCGTCGCCGTCGCTTCGCGGCAAGAAAAAGGTTCGCCGCGGTCCGCACACCCACTTTCGCGGAGCGCGCATCTTCAAGAGAAAGTGCCTACACTGTCAAATCAATCTCCATTCCAAGACGTCGTACGCAAAGCACATGGCGAGGTTTCACGGCGGTGCGAGTGTTGTGACAACAACGTCAGTGCCGAAAGCGCCAGCGCCAAGAGTCGAGGCGCCAGCAGTTGCGGCAACCTCGAGAGCCAAGAGTGGCCAGAGTGTGATTCCGGTGGTGGACACGAGTGCCGACGACGTCGAGGAATTGATCGAGGACGTGGAGGAAGAATTGGAGAATTTGGGCGAGGATGCACCCTTGACGCCCGTCCAGCAGAACATCATCAGTCAGCTCAAGACCTACTCGTGCTACTCGTGCGACGAGTCCTTCCAGGATCGGCGGAGCACTCTCAATCACATCCGTCAGCACATGCCGGACTTGCGATCCTACACTTGTGTCGCCTGTCTCACCGAGTTTCCCGATCGTTCCACCTACAAAAAGCACTGCGAGGCGTCGTTTGAGTGCGCGATGAAGATTGCCCTGGTTGTTCCGGACCAGGGCACGGAGAAGTACTTCACCTGCAACATGTGTCTGCGACCCCTGTCCAACCGGAAGGATCTGCTGACACACTTGTCGAAGCACTCGGACAAGCAGTACGAGGAACTGATGTCGTCTCCCGCGGCACCACCAAAACTCACGCCGATGGTCTCCTCGACGCCGAATTTGCCGTCGTCGCGACAGTCGGCTGACATTCCAATTCGGTCGCCGTACGTGAACGGCGATCCGGCCTGCAATCACGAGTGCGATTTGTGCGGCATGATCTACCGATACAAGCCGAATATGGTGAAGCATCGTGAACTCTGCAACAGTTTGCAGCCGGAAGCGCGTACTTCGTACAAGTGTGTCGACTGTGGCATGACGTTTCTGGTGTTTAGCAAATTTCACAGTCATGTGACGACCGAGCACAGAAAGAAGGAGTTGAAGTGTCCGAAGTGTGCGGCGAAATTCCGCTCGCCGAGTGACTATCTCACGCATCACGAGTATCATCGAATGGGGAAGAAGGAGTCGTCTTCGTCGAGCCGGAATTACAAGAGTCAGGAGGTGGTGGTCGAGGAGGTGCAGGAGAGTCCCCAGAAACGAAGGTTCAATTGTACACTGTGCAGTTTGCAGTTTTCCACGCGAGTCGAACTCACCGAGCATCGTAATCTGCATCTGAAAGTCAAGATCTACTCGTGTGTGATTTGCCGGAGTATGTTTAGTAGCGCCGGAGCTCTGGAGATTCACATGAAGGATCATGGAATTGATGATCCGAATGAGAGAACGGCGAACAGTTCGTGCATGGAGTATGGACAGGAGGAGGGTTTAAATACGTCGAAGAATTCGAATCCGCCGCTCCGGAAGAACGAGTGTTTCGAGTGTGGCAAGACATTTTCGAATTACGCGAATCTGCGAAGGCACATAAGGAATGCGCACGAGGACGAGCGACGCATTGACTGCTCGGAGTGTATCCGCACTTTCAAGAGCAAGGAGGCCTACGAGGATCATCTCAGAAGTGCACACAATCCCGAGAAGACTGTCTTGCAGTGTCCTCAGTGTCCGAAGACGTTTGTCTTCCAGGCGAATTTGGATCTGCATCGGCGCAATGTGCACATCAATAAACCGGAGCCGAGCAATCACGAGTGCGATGTGTGCGGTAAATCGTTCCTGGAGGAATCCTCGCTGAAGATCCATCGCGGCTGGCACAATCGCGCCAATTCGCGTTTCAGTCTCGAAAACTACGAGCGAGATCGACTCGCAGTGCCGAATCCGAGTGTTGCCAAACCGGCCAAGGCGAGAAAGTCGTTTCCGAATGTTCCTCTTCAGCAGCAATTGCAACTGCAACAGCAGCACCATCAGCAGCAGAagcagcaacagcagcagcaacaacagcAGCAACAACAACAGCAGCAGCGTCAACAAATGCCCGAGCTTCAGTGTCAGGTCTGCGACGACAAATTCTTCGACGTCGCGGAATTGAGGAAACATGTGTGGGATGTTCATTGTGCTCGTGCAACCAAAGTCGAGAAACCATTCGTTGTCGGCGACCTGCAGTGTGAGCTCTGCACGAATATCCTGCCCGATCAGCAGAGTCTCGAGGCGCACATGGAGTGGCACGAACGCAATCCAATTTTGAGCAACAACTATGGCAACACGAATGCGTACCGTTGCGATGTTTGCGACAAGTACTACAGTTCACTCAAGATCCTCGCGAAGCACAAAAAGTTGCACAAGCAGGTTGCCCAGCCGCTGAGATTCCAGTCGCTGCCGATGAAGAGGCCCTCGTGCAACGTTTGCGGCAGGTGCTTCACAGCCGAGTCTTCGCTGAAAAGGCACAAGGCAATGTCGCCCGAGTGCCAGTCTTACTTGTCGGGAAGATTGACAGAGGAGCCGCCCCGAAATCTGGAGGATTCGATCTTCAAGAAGAAGCCTGTGACCTGTCACATTTGCAAGACTGTCTTCCCAAGTATGAGCATTCTGTATCAGCACAAGCAGCTGGCGCACAAGGTGGGCTTCAACAAGGACAGGAAGTCGCCGAGCGGCGAGTGCATGCCGCTGGCGAGTGGCGAGGGTGGTGTCTCGTGCAATGTTTGCGGCAAGCAATTCCCCGGCCTCTCCAATCTCAAGCAGCACTTCACGATCAAGCACAAAAATGTCACCCAGCATCCGTGCACAATTGCCAATTGCAAAATGATCTTCTCGACGTCGCATGCACTGAAAAATCACGAACTCACGCACTCGAACATGATCTACAGTTGCGGTCTCTGCGAGAGGCACTTTTTCCACCGAGGCGCGATCATCAAGCATGTGTTCAACGCCCACAAGATGATTTATCAGGCAACGGGCGACAAGGATTCTCTGTTCAAGGAGACCGATTTGAGTACGTATGTTGTGAAGGGCGCGACTGGCACTGTTTGTCCGCGATGCCGAATCAAGTATCCCAATATTAAGGCTATGAAGATTCACTACTTCAAATTCCACGAGACTTTTGCTTAA
- Protein Sequence
- MNEIEELQGLESACRLCLTTDETRSSIFGTAHSVVPLTQKIQNCVTVEGRSAVKEWRRSGVKEERTSGVKEERTGGVKEERTRIVKYGRSGVKEISREDKLTTLICITCVNKVNQWHQYKQLCLQSQDKLKEWLTRQSKTSSVATVKQEPSTQETEEESPQLLPDKDKIPEETSPPPEGPSDEIEKLMAVDRPAEVETPAEIEAPVEIEGETDAAVETPVEIESPVEIDTPVEIDTSAGAETPVDIETPMEVDTEVEERVERETRGSAKRRLSKETVTAEKRSEAVSIKIEPPDDESQEVVDIVTPTEILLRNPLATPANGKEDQPAEPDSTQKIVPLSSPSLRGKKKVRRGPHTHFRGARIFKRKCLHCQINLHSKTSYAKHMARFHGGASVVTTTSVPKAPAPRVEAPAVAATSRAKSGQSVIPVVDTSADDVEELIEDVEEELENLGEDAPLTPVQQNIISQLKTYSCYSCDESFQDRRSTLNHIRQHMPDLRSYTCVACLTEFPDRSTYKKHCEASFECAMKIALVVPDQGTEKYFTCNMCLRPLSNRKDLLTHLSKHSDKQYEELMSSPAAPPKLTPMVSSTPNLPSSRQSADIPIRSPYVNGDPACNHECDLCGMIYRYKPNMVKHRELCNSLQPEARTSYKCVDCGMTFLVFSKFHSHVTTEHRKKELKCPKCAAKFRSPSDYLTHHEYHRMGKKESSSSSRNYKSQEVVVEEVQESPQKRRFNCTLCSLQFSTRVELTEHRNLHLKVKIYSCVICRSMFSSAGALEIHMKDHGIDDPNERTANSSCMEYGQEEGLNTSKNSNPPLRKNECFECGKTFSNYANLRRHIRNAHEDERRIDCSECIRTFKSKEAYEDHLRSAHNPEKTVLQCPQCPKTFVFQANLDLHRRNVHINKPEPSNHECDVCGKSFLEESSLKIHRGWHNRANSRFSLENYERDRLAVPNPSVAKPAKARKSFPNVPLQQQLQLQQQHHQQQKQQQQQQQQQQQQQQQRQQMPELQCQVCDDKFFDVAELRKHVWDVHCARATKVEKPFVVGDLQCELCTNILPDQQSLEAHMEWHERNPILSNNYGNTNAYRCDVCDKYYSSLKILAKHKKLHKQVAQPLRFQSLPMKRPSCNVCGRCFTAESSLKRHKAMSPECQSYLSGRLTEEPPRNLEDSIFKKKPVTCHICKTVFPSMSILYQHKQLAHKVGFNKDRKSPSGECMPLASGEGGVSCNVCGKQFPGLSNLKQHFTIKHKNVTQHPCTIANCKMIFSTSHALKNHELTHSNMIYSCGLCERHFFHRGAIIKHVFNAHKMIYQATGDKDSLFKETDLSTYVVKGATGTVCPRCRIKYPNIKAMKIHYFKFHETFA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00200995;
- 90% Identity
- -
- 80% Identity
- -