Basic Information

Insect: Acraspis erinacei
Gene Symbol: Hr39
Assembly: GCA_035041075.1
Location: JAWWLR010000165.1:22472072-22493194[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 2 1e+05 -6.6 12.0 85 166 177 271 96 315 0.52

2 4 0.96 4.8e+04 -4.2 3.6 77 147 314 359 277 381 0.37

3 4 3.4e-08 0.0017 20.3 0.0 1 21 472 492 472 497 0.92

4 4 1.8e-72 9.1e-68 232.0 0.0 86 408 527 849 502 849 0.80

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	2	1e+05	-6.6	12.0	85	166	177	271	96	315	0.52
2	4	0.96	4.8e+04	-4.2	3.6	77	147	314	359	277	381	0.37
3	4	3.4e-08	0.0017	20.3	0.0	1	21	472	492	472	497	0.92
4	4	1.8e-72	9.1e-68	232.0	0.0	86	408	527	849	502	849	0.80

Sequence Information

Coding Sequence: ATGTCGCGACCACGTGTTTGGTCTTTCGAGCACGTTTTATGTGCGAGGGgTAAAAATGTCTGCAAGTATCTGGGTGGACAAAATGGCGTGACGGTTTCGGTAGTATCGAGTTGTGGGTCCGGTGGCGTTGATTCCGGTACCAGCATCGGATCCACGGAATCACCAAATGTTGATGATGTGGAGGACAGCGATGGGGAAGTTAGTAAAATAGACTTCCGAGGGGTCAATTTAAGAACGAAGAAAAAACGAGATGGATCTGTAGGACATGACAACGAAAGCTGCAACGAAAATTTGCAGCAACAACCAGAGAGACCTATGTCCTGGGAAGGAGAACTCTCCGATCAAGAAATGTCTTCTAACACTATTACGAATCAGGACCATGAGGAAACTTCAATGGAAGGAGTTCAGGTCTGCAATGCGAGTCCTGGACCTCAGGAACACAAGTTCCCAATAAAACCGGAGCCGGATTTCCGGTCGAGTCCGGGACTTTCACATAGCCTAAACGACACAGTACTACCATTGTCTCATGCTCAACAAGTCCAGCAGCAACAGCAGCATCAACATCAGCATCGAGGAGGAGGACTGGACAGTCTCGAGCAAACGCAGCAAAATGATCTGCCTTTGCTTGTTGGAAAACTCCTCGGTGGTTACAATTGTTCTACACCCAATCACAGTCCTGTGCTCAATCCAAGGCATCATCTGACCAAACACAGTCACACGAGGTCTCAGGTTCCGTCGCCTGATTCCGCAATTCACTCAGCCTACAGTGTCTTCAGTTCTCCAACACAGAGCCCACATGCAGCACGACATTCGGCACTGGGACCAGGAAGTCCAGTTCCTTCGTCCTCACTATCCCTCTCACGTCACAGTTTCAACAACTCAACATCCTCCCTATCATTATCACTTTCGCACTCCCTCTCGCGAAACAACTCAGACGCCTCTAGTAGTTGCTACAGCTACGGATCTCTCAGTCCCCCCACACACTCGCCAATCCAACAGCCAAGACATGCACATCCCCAGCATCATCATCAAGTCGCTCAAGGCAGTCCCTTGCACCTTCCAGCCCAATCCACTGGAGCTAGCCATCACTACTCAGCTCCAGGTTCCGAGGTCTCTTCCGAAGGGCATCCTGATGATCAAGATGACTGCAGAATACCATCAGCACCCACCGGGATCTCCACCCGCCAACAGCTGATCAACAGTCCCTGTCCGATTTGTGGCGACAAGATCAGTGGCTTCCACTACGGCATCTTTTCCTGTGAATCCtgcaaaggatttttcaaaagaacagTCCAAAACCGGAAGAATTATGTCTGTCTGAGAGGAGCCGGCTGTCCAGTAACGGTAGCGACACGAAAAAAATGTCCAGCCTGTCGATTCGACAAATGTCTCAACATGGGTATGAAACTCGAGGCGATCAGGGAGGACAGAACTCGAGGCGGACGAAGTACCTATCAGTGCACGTATACCTTGCCAGCGAATCTCATCGGTAGTCCTGCCGGAGGGATGTCTGGGGACAAAATGACCGGAGGATCTTGTAGTCCCGCGCCTCCCGGATCAGAGCATCATCATTCCATGCGACATCATTCGAATCATTCTCATAAAATGCAAGCAGTGCCACAACTTTTGCAAGACATCATGGATGTGGAGCATCTTTGGCATTATAATGATAATGATAGAGTTGGGGGAAGTCAGAGCAGTGGTGGTACTGGCGGAAATGGGAGCGTCAGTGGCAGCAGTGCAAGTGGAGATTCTCTCGCTAGCGGAGCCACCTCGAATGGAGCGAGTGGAAGTAATGGAAACATCAACAGTCGAGAACCGGCGAGGCCGAATTCTACGGGTTCGGTACCAGCCAGTAATCATGATCATCAACAGCACACATCGACGAGTGCTTCGGCCAATATCAGCCCCAGTCCTAACCCCAGTTGCAATCCTAACGGAAATCCCACCCAAAATCCTGACTTTTTGTCGAACCTGTGCAATATCGCGGATCATAGACTGTACAAAATTGTCAAATGGTGTAAAAGCCTGCCGCTATTCAAAAATATCTCGATTGATGATCAGATTTGTTTGCTGATCAACTCGTGGTGTGAGTTATTGCTCTTCTCGTGCTGCTTTCGAAGTATGAGCACGCCTGGAGAAATTAGAGTGTCACTGGGAAAGTCGATTACCCTGGAACAGGCGAGGCAACTTGGCTTGGCCACTTGTATTGAGAGGATGCTGGCTTTTACGAATAATCTTAGGCGGCTCAGGGTGGACCAGTACGAATACGTAGCGATGAAGGTGATAGTACTCCTAACATCGGACACAAGTGAACTGAAAGAGCCCGAGAAGGTGAGGGCTTCTCAGGAGAAGGCTCTCCAGGCCCTCCAACAATACACAATCGCCAGGTATCCGGAGATGCCAGCAAAGTTTGGTGAACTTCTCCTGAGGATTCCTGACCTACAAAGAACGTGCCAAGCAGGAAAGGAGTTGCTGAGCGCAAAACGTGCCGAAGGCGAGGGTTGTTCGTTTAATCTCCTGATGGAGTTGTTACGTGGGGACCACTGA
Protein Sequence: MSRPRVWSFEHVLCARGKNVCKYLGGQNGVTVSVVSSCGSGGVDSGTSIGSTESPNVDDVEDSDGEVSKIDFRGVNLRTKKKRDGSVGHDNESCNENLQQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCNASPGPQEHKFPIKPEPDFRSSPGLSHSLNDTVLPLSHAQQVQQQQQHQHQHRGGGLDSLEQTQQNDLPLLVGKLLGGYNCSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGPGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPIQQPRHAHPQHHHQVAQGSPLHLPAQSTGASHHYSAPGSEVSSEGHPDDQDDCRIPSAPTGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLIGSPAGGMSGDKMTGGSCSPAPPGSEHHHSMRHHSNHSHKMQAVPQLLQDIMDVEHLWHYNDNDRVGGSQSSGGTGGNGSVSGSSASGDSLASGATSNGASGSNGNINSREPARPNSTGSVPASNHDHQQHTSTSASANISPSPNPSCNPNGNPTQNPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGCSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00059522;
90% Identity: iTF_00980232;
80% Identity: iTF_00011215; iTF_00011125;