Afla014475.1
Basic Information
- Insect
- Achlya flavicornis
- Gene Symbol
- -
- Assembly
- GCA_947623365.1
- Location
- OX392493.1:8624303-8627475[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.0079 0.51 11.3 2.2 1 23 276 299 276 299 0.97 2 18 1.5e-06 9.4e-05 23.0 1.9 1 23 304 326 304 326 0.99 3 18 0.0017 0.11 13.3 1.9 1 23 356 379 356 379 0.97 4 18 0.00093 0.06 14.2 0.5 2 23 440 462 439 462 0.96 5 18 3.4e-05 0.0022 18.7 1.3 1 23 468 491 468 491 0.95 6 18 0.036 2.3 9.2 0.4 2 21 496 515 495 516 0.93 7 18 0.13 8.6 7.4 0.1 3 23 526 547 524 547 0.92 8 18 0.59 38 5.4 0.7 1 23 552 575 552 575 0.92 9 18 0.0011 0.07 14.0 0.1 2 23 588 609 587 609 0.94 10 18 0.0035 0.23 12.3 2.2 1 23 615 637 615 637 0.98 11 18 7.8 5e+02 1.8 0.1 2 10 643 651 642 653 0.87 12 18 0.00019 0.012 16.3 1.1 1 23 674 696 674 696 0.97 13 18 0.041 2.6 9.0 0.0 3 23 702 722 701 722 0.93 14 18 0.0027 0.17 12.7 0.9 2 23 735 757 734 757 0.96 15 18 0.0054 0.35 11.8 3.8 1 23 763 785 763 785 0.98 16 18 0.00026 0.016 15.9 5.7 2 23 792 813 791 813 0.96 17 18 3.3e-05 0.0021 18.8 1.1 1 23 819 842 819 842 0.96 18 18 8.6 5.5e+02 1.7 2.3 3 23 849 870 847 870 0.93
Sequence Information
- Coding Sequence
- ATGATTGAAGAGGATACTGAACATGAAGAAATCTACGCCATACATGTAACAAACGAAGCAAACAATATCGAATGGCTGAAACAAAGGCTAAACAAAGTATGGAGCTGCCCAAAGTTCTGTGGCATTTGTCTAGAAGATGGCGGGAACCTGTACTCCCTTGAAATGGAGTTCAAATTCGGTCGACAGACCAATGCCAAGTCTTTGCAGTACCTCATTAATTATGTATTTAATGGCGATATCGAAGAAATCCTGGCAAGCTTGCACGTCTGCGAACAGTGCGCAGAAAAAACAATACAGTCATACCAATTCATACACAAAACAAAACGGACTGCGAAAATCATGGATAGCTGTGTAAAAGATATGATGTCCAAAGTTGTAGATATAGACGAACGATTGCATGGATCTACAAATTATGAAAATGCTAATGTCATGATAGTTCTTGAAACAGATACAGAAATGAATGATTATATTGACGACATCACCACATTTATCACTGAAATTGTTCCAAAAGAAAAGAATTCTAAAATTAACATTTCCCAAGAAATCCCCAAAGAGATACTTAAAGTTTTCGAACAAGCTAAAGAATCAGAGGCAAAAGAAACTAAACCACCAGTAGAAACACTCAAACCACGAATAAATGTTCTCAAACCACAAGAAAATGTCGTTAGAGAATTTAAAAAACCTAAACCTATAATAAGAAAAATACTCGAAAAAAAAGCTATAAAAAGCGAAGGGTCTCCGAATATATCTTTGAAAGAGGGAAAGATTATTATAAAGCCGTTATCTGCATCGAGAGACCCGAACTTAGCTCCAATTTTTAACACATATAGATGCACACAATGTCCTGATATATTCACAACATACAAATCTTTGAAAGATCATGAAAAGAAAAAACACATGACGTTTGTTTATAGTTGTAATATCTGTAATAAATCTTACAACACTCAGCAATACTTGAATGTGCATCTTAAGACGCATTCTAAAGCTAGATGCAAGATTTGTAGATTAATTCTACCCGAAGAAGATTTGCTCCATCATTTGAGATTGAAACATGAAATGCTTGTGCACGTCTGCAAATTCTGCAATCAAGTTTACTATTCAGCGGAATCATTGGAAACACATTTCAAAACGGTACATTTGGTTAATGACATAAAGTCGAAATTGCAATGTGTTATGTGTCTCAGAAACTTTAAAGAAGAACACATGAGGAAGCATCGGTGCAAGTTCTTTTGTCCAGAGTGTATAGTTATGCCATGCATACACCACAGCTACCTAATGTCTTATAGAGAACAAATATTGAACCACGTTTCTGTTGTGAAATGCATGGACTGTGATTATACTACTCGAAGAAAAGAATATCTAATAAGTCACGCCAATCGGGAACATCTAGGACACCATCCCTTCACTTGTGACGATTGCGGACAACAATTCTACACTAAAATGAGCTTAAAAACGCATATAATACAATTTCACCAAGATCTATGTGTTTGCGAATACTGCGATAATACAGTCAAAGATAAAATTAAATTGGAAGCGCATAGGAAAGCGTGTAAGACTATTATAAGGGCATACGGTTGTGATATGTGCGTAGCTTCATTTGACACTGCACAAGAATTCGAGAAACATGTGGAATTAAGACATAACGATGGTATATACCCCTGTAATTTATGCAAGAGGGAATTCTTAACACTTTTAAAGCTTGAAGAGCATCATGCGAGAGCGCACAGTGGTATACAATATAAGAGAAGAAGGAAGTTCATAGAATGCACGATTTGCGATATAAAATTCAATGATTTAAGAGAATTGACTCAGCACGAGGAACTACATGGGCCTAGCGTGAAATACCCCTGTAAGGTGTGCTCGAAAGAGTATACAAGTTTGAAGAAGCTTTATATGCACAAACAACGGCATTACACAGACAGAGTGCAATGTGACAATTGTAATAAGTCGGTTTCAGCGACATTCTACCCTCAACATGTGATCCGTTGTGCTTATAAATCCAAAACACCGTCTAAGGGCCACATTTGTGAGACCTGTGGCAAAATTTTCCGTGCCGTGTCATTGTTGAAGATGCACCAAAAAAGTCATCAAAAACGTGAGCCTTGTTCCATTTGCGGTAAAATGGTGAAGCCTGCATATTACAAAAAGCATATTGATGTCGCTCATAGAGGGTTGAAACGTCCTCCCGCGCCTAAAGGAGTAACCTGCGATTTGTGTGGTCATAACATGAGGAAGAACTCTGATTTGGAAGCCCACATGAATAGATATCATTTGAAGATTAAGCCATTTGTATGTCATATATGCAGCAAAGATTTTTGCGGTAAGATGAGGTTAAGAGAGCACGTTTTGACTCACACGAGCGAAAATAGCTGTTTTTGTTCGCAATGCGGGAAAAAGTTCGCGAATCGTGTTTGTTTGAAAATGCATATACGTATGCATACAGGGGAGAATCCATATCCTTGTGATATTTGTGGAGAAAAATTCAGATCCTCAAGTATGATGAAGACGCATAAATTGAAAAAGCATCAGGAGAAGACTGTGTGCTGTCCACTTTGCGACGGCATGTTTTATATCGTTAGGGATATGAGACACCACTTTAAGAAAGTGCATTGGAAGCGCAAGGATAGGCCATTTAATCCGAGGGAGGTTAAGGAATTGAATGAGAAGTATTATCACTTGTTCGACGATGGTAGATTTCCAAAGCTGGATGATGATTAG
- Protein Sequence
- MIEEDTEHEEIYAIHVTNEANNIEWLKQRLNKVWSCPKFCGICLEDGGNLYSLEMEFKFGRQTNAKSLQYLINYVFNGDIEEILASLHVCEQCAEKTIQSYQFIHKTKRTAKIMDSCVKDMMSKVVDIDERLHGSTNYENANVMIVLETDTEMNDYIDDITTFITEIVPKEKNSKINISQEIPKEILKVFEQAKESEAKETKPPVETLKPRINVLKPQENVVREFKKPKPIIRKILEKKAIKSEGSPNISLKEGKIIIKPLSASRDPNLAPIFNTYRCTQCPDIFTTYKSLKDHEKKKHMTFVYSCNICNKSYNTQQYLNVHLKTHSKARCKICRLILPEEDLLHHLRLKHEMLVHVCKFCNQVYYSAESLETHFKTVHLVNDIKSKLQCVMCLRNFKEEHMRKHRCKFFCPECIVMPCIHHSYLMSYREQILNHVSVVKCMDCDYTTRRKEYLISHANREHLGHHPFTCDDCGQQFYTKMSLKTHIIQFHQDLCVCEYCDNTVKDKIKLEAHRKACKTIIRAYGCDMCVASFDTAQEFEKHVELRHNDGIYPCNLCKREFLTLLKLEEHHARAHSGIQYKRRRKFIECTICDIKFNDLRELTQHEELHGPSVKYPCKVCSKEYTSLKKLYMHKQRHYTDRVQCDNCNKSVSATFYPQHVIRCAYKSKTPSKGHICETCGKIFRAVSLLKMHQKSHQKREPCSICGKMVKPAYYKKHIDVAHRGLKRPPAPKGVTCDLCGHNMRKNSDLEAHMNRYHLKIKPFVCHICSKDFCGKMRLREHVLTHTSENSCFCSQCGKKFANRVCLKMHIRMHTGENPYPCDICGEKFRSSSMMKTHKLKKHQEKTVCCPLCDGMFYIVRDMRHHFKKVHWKRKDRPFNPREVKELNEKYYHLFDDGRFPKLDDD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01417127;
- 90% Identity
- iTF_01252100;
- 80% Identity
- -