Afla001616.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Achlya flavicornis
Gene Symbol
zfh1
Assembly
GCA_947623365.1
Location
OX392494.1:984494-990422[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.00016 0.01 16.6 0.2 2 22 113 133 112 133 0.94
2 26 4.8 3.1e+02 2.5 0.4 2 23 138 158 137 158 0.91
3 26 0.0064 0.41 11.5 4.3 1 23 163 185 163 185 0.98
4 26 0.00089 0.057 14.2 1.5 1 23 190 212 190 212 0.96
5 26 0.31 20 6.2 5.7 2 20 216 234 215 236 0.91
6 26 0.00052 0.033 15.0 1.4 1 23 248 271 248 271 0.97
7 26 0.00017 0.011 16.5 4.0 1 23 277 299 277 299 0.98
8 26 0.087 5.6 8.0 0.9 5 23 309 327 307 327 0.97
9 26 0.16 11 7.1 2.8 1 21 345 365 345 365 0.95
10 26 7.5e-06 0.00048 20.8 2.4 2 21 503 522 502 523 0.93
11 26 0.15 9.7 7.2 0.2 2 23 528 549 528 549 0.94
12 26 0.0039 0.25 12.2 0.3 1 23 554 577 554 577 0.96
13 26 8.9e-05 0.0057 17.4 0.1 1 23 582 604 582 604 0.94
14 26 0.00022 0.014 16.2 1.0 1 23 640 663 640 663 0.93
15 26 2e-05 0.0013 19.4 2.8 1 23 669 691 669 691 0.98
16 26 5.8 3.7e+02 2.2 0.6 1 23 725 748 725 748 0.88
17 26 5.5e-05 0.0035 18.0 0.7 2 21 874 893 873 894 0.93
18 26 2.5 1.6e+02 3.4 0.0 3 23 901 922 899 922 0.95
19 26 0.0046 0.3 12.0 1.9 3 23 929 950 928 950 0.97
20 26 0.0001 0.0067 17.2 0.8 2 23 956 977 955 977 0.96
21 26 0.91 59 4.8 0.5 3 20 982 999 981 1001 0.91
22 26 3.8e-06 0.00024 21.7 0.9 1 23 1027 1050 1027 1050 0.95
23 26 0.00048 0.031 15.1 0.5 1 23 1056 1078 1056 1078 0.95
24 26 0.11 6.9 7.7 0.1 1 23 1084 1106 1084 1106 0.97
25 26 0.0015 0.098 13.5 0.5 1 23 1112 1135 1112 1135 0.94
26 26 0.00042 0.027 15.3 0.7 3 23 1142 1163 1140 1163 0.95

Sequence Information

Coding Sequence
ATGGAGTCGTCGACATCGCTGCCTAACAGACTATGCATCCACTGCGTGGACAAAATATTACCTATCATACCGTTCATAAAACTTTGCAAGGATTCCGACAGCAAGTGGAAGCATGTGATAGAGCACTTGACCCTACCGTCAGTACCTAAACCCAGAGTCTTCGTGCTCATATCAAGCGATTGTCAGAAACGAGAGCTGGTCCATTCTACCAAGAAGAATATCAAAGACAATACAGAAGCGGTAAAGGTTCTACAAAAACGTTTAATATGGAAAAAGTGCAATAGCATACGGCGCGAGAAAGAGAAACAATTGAAATTATCAAATGATAAGAACATGTCGTGTCCGGAATGCGAAAAATCTTTCTATACCATTGACACACTCAATAATCACATCAAACGTGTAAAGAAAAAGATGTGCCCGCACTGCAATCTTATTTTGGATCTAGAGGCGTATAAATCTCATGCAGAAACACATAATGCGAACGTTTATTCTTGCGATATATGTAATGAGTGTTTCGTATACAAGAAATACTTCTTGTTGCATAAATTAAAGCATTCAAGGGGCAAACACATATGTCCTGAATGCAAGCTATCATTTTCAAACATGGACAGGCTCTCCAGACATGTATCGAGACATAAGCAATGTGTTTGTTCGACGTGTAATAAGAAATTCACTAATAAAATCTGCTTTAGCAATCACAAGATAAACTGTGCTCAAAGCAGAGATATTAGTGTAGAGAAATTCATCTGTGATTATTGCTCGAAAGAGTATAATTTTAAAATGGCATTGAAAATGCATATGAAAATAAAGCATCTCGCAAGAAAGAAGTTTCAATGTGACAAGTGTGGCAAATCATTTCCATTTAAAGCACATTACATTGAACATGAACACACTCACAAGAAAGTCTTGGATAGATACGTCTGCAAGTGTGGAGCGAAGTATAGTTCTCGTAGGGGATACGAGAAGCATTTGAAAAAGCATTCAAGGGAAGATGAAATAAAAAAGGGGAAAGTTTCCAAAGCAAATTATTCATTTAAATGTGCTAAATGCAAAGATACTTTTGCTAATAAGAAAGACTTTTATAAACATACTAAATGTTCGGAGGCCAGTTCTCGTGGAGTTGGACGACGAACCGACTTTGGACAATTGTTACAATTAAACAGTTGTATTAAACCTCAAATCGATGTCCTGGAGGAGCCGTCCTTGCCTCAGGGGTTATGCAGAACATGCTCTGAAGACATCGTCACAGCGATACACATCGGACAACTGAGCAAACTCTCCGCACAGCACTGGGCCTCGGCGACCACATACCTGTCCCAAATCTACGACGCGACTGATGAAGATAAATGCGTCTATGTCTTCTATAATGGCGAAGAAAATACTATAGTGAAAGATCAAATTGATCGAGTCCCAAATGTACAAGAAGCTCTCTGGAGATTGAACGGAAAATTAGTTTTTGATAGCCCTAAGCCAAGGAAGATAAGACGTTTAAATGAGGTTTCATGTCAATGCCCGATTTGTGGCAAAGCGTTCACAAATCCATGTTACTTAAATAAACATTTGAAAAGTACCCCTAAAAGATCTTGCAGCGAATGTGGTCTAGTGGTACCGAAGAAGAATTTGAGCAAACATTTATCCAAAGCCCACGATATAGTCGTTTATAGTTGCACCCGTTGCAACGAAGTGTTCGAAGATGATGAATATTTGATGCAACATTGGCTAAAATCTCACGGCGCAAAGAAGTTCTCCTGCGAAGACTGTGGTCGGAGTTTTGTGAACGAACGAGCGTTGAGCGCTCATGTGTATGCCCACAGCCTTTTCCACTGCAAATCTTGCAGCCTTAGCTTTGAGAATCGGAAATGTTGTAAGCATCACGAGAAGCAATGCAATTCCGAGCAGCAACCAATCTCTTCGGCCTACGAATGCGACCACTGCGGTGTGTCATACAAAAAAAAGCCATCTTTAAAGATACATATAGTCCAAAAACATATGAATGTACTCCCATTCGTTTGCACAACATGTGGGAAGCGTACATCAACTAAAGCTCACTTGAGATCTCATGAAATGACGCATAAGAAAGTGAGGAAGATATACGAATGTTATTGCGGAGCGAAATTATTGTCCGAGCTGGGATATCAGTTGCATCAAAGGATACACAGTGGAGAGAAGCCATTCGCGTGTGACGAGTGCGGGGATAGATTCCTATCCTCTTCGCGGAGGTTGGATCATATAAAAAGGAAACATAGAGGCACCAATGGCCTGCCTTATGCTTGCGAGAAGTGTGCGGCGCGATTTGTAAAAGATGAAGCTCTCTGTCCACCAGGAGTATGCGTTGGTTGCGCCAGCACCGCCCTCGCCGCGCAGGAGTTCAGCATCTTTGTTAAAAACGCACAAAAAATGTGGCATAAAGCCGTCACAAGCTTATCGGTCCTTTCCACTTCCACAGCGCCCAACGTCAAATCACTATACGCCTTTGTCAGAAAAACTGATCTATCAATCCAAACCGTTAAAGACTTCGCAGGCGGTGACACGAAAACCATTCTAAACCGATTAAAAAACAGATTTAGTAAAAAGCCGGTTAATAGGAAGCCGAGGAACGCGCGCGCAGGGCCTTCATGCATTTGCCAGGACTGTGGGAAAACGTTCATCAGTCCATATTACTTGAATATGCATTTAAAAAACAGTGGACAAAAGGATGCTTGTTTAATTTGTGGGGCGGTCGTTTTTAGAGGACGCGAAATGAAGGACCATCTCTCAACAGTACATAAGGAAAAGGTGTCACTGTGTAAACATTGTCCTATGCTATTTAGTAGTGAGTCCAAACTTATGAAGCACGCAAAAAAAGCACATAGCCCCGGTGTCCTAACTTGCAGCGATTGCGGAAGGACTTTCCCTAGACACGCATCGTTTGAGCTGCACGCGCAAATGCATGCAGTCCGCATATGTCGAGCTTGCGGGATACAGTTTACCAATCGCGGCTGTTATAGGGAACATCGCGCACAATGCGAGCCAGACGCGAAACCTGACGCGCAATCTGTACCCCGAAACAGACGGTCGAATATCCGCGACCCAGCTCAATATACCTGCGATCATTGCGGCAAAACTTACAATTCTAGGCCGCAATTGAAGAACCATATCATCTGGATTCATATGGACGTGAGACCTCATCAGTGCCAGTGGTGTGGCAAACGTTTTTATACTCCAGCTAGGTTAGCTGAGCATACTGTAGTCCATACTCGTGTCAGAAACTTTGAGTGTGATATTTGTGGCGCGAAATTGGTTTCCAAAATGGCCGCCGTTTACCACAGGAGGCGTCATACAGGCGAGAAACCCTATAAATGTGAAGACTGCGGAGAGACGTTCATATCTGCCTCTAGAAGATCAGAACATGCAAAGAGAAGGCACAATGTGTTGAGAATTAATTGTACTCTGTGTACAGGTACTTTTGTGAGGCGATATGACCTTAAAAAGCATATGGACAAAGTACATAAAAAGGAGGACGAACCGGACGAGCCGATTGTGAAGCGGGATTTTGGGGAGTTGTGCGCAATAGAAAATTGA
Protein Sequence
MESSTSLPNRLCIHCVDKILPIIPFIKLCKDSDSKWKHVIEHLTLPSVPKPRVFVLISSDCQKRELVHSTKKNIKDNTEAVKVLQKRLIWKKCNSIRREKEKQLKLSNDKNMSCPECEKSFYTIDTLNNHIKRVKKKMCPHCNLILDLEAYKSHAETHNANVYSCDICNECFVYKKYFLLHKLKHSRGKHICPECKLSFSNMDRLSRHVSRHKQCVCSTCNKKFTNKICFSNHKINCAQSRDISVEKFICDYCSKEYNFKMALKMHMKIKHLARKKFQCDKCGKSFPFKAHYIEHEHTHKKVLDRYVCKCGAKYSSRRGYEKHLKKHSREDEIKKGKVSKANYSFKCAKCKDTFANKKDFYKHTKCSEASSRGVGRRTDFGQLLQLNSCIKPQIDVLEEPSLPQGLCRTCSEDIVTAIHIGQLSKLSAQHWASATTYLSQIYDATDEDKCVYVFYNGEENTIVKDQIDRVPNVQEALWRLNGKLVFDSPKPRKIRRLNEVSCQCPICGKAFTNPCYLNKHLKSTPKRSCSECGLVVPKKNLSKHLSKAHDIVVYSCTRCNEVFEDDEYLMQHWLKSHGAKKFSCEDCGRSFVNERALSAHVYAHSLFHCKSCSLSFENRKCCKHHEKQCNSEQQPISSAYECDHCGVSYKKKPSLKIHIVQKHMNVLPFVCTTCGKRTSTKAHLRSHEMTHKKVRKIYECYCGAKLLSELGYQLHQRIHSGEKPFACDECGDRFLSSSRRLDHIKRKHRGTNGLPYACEKCAARFVKDEALCPPGVCVGCASTALAAQEFSIFVKNAQKMWHKAVTSLSVLSTSTAPNVKSLYAFVRKTDLSIQTVKDFAGGDTKTILNRLKNRFSKKPVNRKPRNARAGPSCICQDCGKTFISPYYLNMHLKNSGQKDACLICGAVVFRGREMKDHLSTVHKEKVSLCKHCPMLFSSESKLMKHAKKAHSPGVLTCSDCGRTFPRHASFELHAQMHAVRICRACGIQFTNRGCYREHRAQCEPDAKPDAQSVPRNRRSNIRDPAQYTCDHCGKTYNSRPQLKNHIIWIHMDVRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICGAKLVSKMAAVYHRRRHTGEKPYKCEDCGETFISASRRSEHAKRRHNVLRINCTLCTGTFVRRYDLKKHMDKVHKKEDEPDEPIVKRDFGELCAIEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01252036;
90% Identity
-
80% Identity
-