Aeph018712.1
Basic Information
- Insect
- Acentria ephemerella
- Gene Symbol
- ZEB2
- Assembly
- GCA_943193655.1
- Location
- CALPDL010000149.1:1540250-1548721[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 9 6.1e+02 1.5 1.1 3 21 461 479 460 483 0.92 2 13 0.021 1.5 9.7 0.7 3 22 506 525 504 528 0.89 3 13 0.12 8.5 7.3 3.3 1 23 542 565 542 565 0.95 4 13 0.067 4.6 8.2 1.1 1 22 570 591 570 594 0.89 5 13 4.6 3.2e+02 2.4 0.4 2 23 615 639 614 639 0.83 6 13 0.013 0.92 10.4 0.2 2 22 645 665 644 665 0.94 7 13 1.5e-05 0.001 19.7 1.6 1 23 724 745 724 745 0.98 8 13 6.8e-06 0.00046 20.7 1.1 1 23 751 774 751 774 0.98 9 13 0.00021 0.014 16.0 1.9 2 20 798 816 797 818 0.93 10 13 0.049 3.4 8.6 1.5 2 23 822 845 822 845 0.95 11 13 0.18 12 6.8 5.5 1 21 852 872 852 874 0.95 12 13 0.002 0.14 13.0 1.9 1 21 880 900 880 905 0.92 13 13 0.017 1.1 10.1 3.2 1 23 911 934 911 934 0.98
Sequence Information
- Coding Sequence
- ATGCTGTCGCCGCGGGACGACGACGATGATGACAGCCATCTGTGCATCAAGTGCAACACTACTATAGTTGGCCTCGAGAATTACGTGAAGCACAGAAAACAAAGATGCGGAAAAATATCTAAACCCGAAACTTCAAAGGCAGATATCTCGAGCATTGATACATTAGACCCTGCGTATAGTCTTGGCGCAGATGTCTTCTTTCAATCTTTGGAGTTACAGAGCAGCGTTAAAAAGACTTCTTTATCCAGACTCACTCCTACACTACCTATATCGAAAGCAGTTTTAGATTCAAAAACGACTTTAGTAGAAGCTTCCACGTCAAGAGATATTCCACGAATGAGTCCTTTGGAAACCAATTTGAGAGAAGAAGACTGGATTGGAGGACATTCCTTAAGAATCAGTGGTCATGAAGATAACCAGACTAAGTTGATTAATGCTGTAGCTAGTATCAGTGGTACGGCTAAAAAAGAAATTACCAGGTCTACTTATAGTATCGCAGCGTATAATGATTTTAAATGTGACGAGGATTTTGATGAGTTAGATGAATCTGAAGAAGAAGAAGAGGAAGAACCTCATGCCAGTTGTATTAAGTGGAAGCTACCACCAAATTACACTGGTGGTAAATGGCGGCCCGCTTCACCTGATCATGAAGACTGGGATATGAGGGAAGAGCAAGAGCACACAGGAGGAAAATGGAAGCCTATAATGGGTGACTCCAACGAAAGAGATGACGATTACGACGTCCCACCACCGGGACACACAAAAGGGAAATGGGTGCCTGGTCATGAAAAAACACAAATCATGCAACCAACATTACAATCAAAGGGTTCTGTTCAATACTGGTGTGGTCCTTGCAATCGGCGACTAGGATCACGCGCCATTTATGAAAAACATTTAATGTCTAGTTTGCACATGAGAAAAGTTCTTCCCGAACATGAATTAGAGTTTTCCGGGCATTTAGAACCGATAAGTTCTGTAAAAAGATCCTTACGTCCCTCTCGCTTTACTGATGACAGCGTTTACGTGCAAGTTCAGAAAAAAGCGGGAAAAGAACTGAAACCGAAACTTACGGTCAAAGTAGAAAAGAAAAAACGGAAACGAAATCCGACCTTTGTACACTGCTCCGGTTGTAAATCGCGGGTGAGATTGCATTTGATGGGAAAGCATTTAATTTCTCATTACCACTTCCGAAAAGCCACTGATATCAAAAGCGAATCTTATCAGCAGTTAATTCTAGGTAATATAGACGCCATCGTCCATCAATCACCTTTTCAGTGCAGCCCATGTAAATTTTATACCAACTGGCTGCCCAATTTTATGCAGCATTGGTTATCTGACGAACATAACAATAAAACAGCAATGTTAGAAGGTAGATTCTGGTGTTCCTTTTGCAAGTTTGATTGTGTAACATCACAAGATATGTTAGAACATATGTCTGGGTCAGAACACAGCGAAGTGGTCGCTGTAATAAATAGATCAATGCCTATAATTATTAGGAAGAAAAACATTATTGCATGTGGGACGTGCAGAAAAGAGTTCAAATATAATGTGGAAATGAGAAGACATTTTAACAGAACTGGCCATAAACCAGCTTATACTGCGACAGATGATTATCAAGAATTTCATAAATGCCGTCAGTGCAGTTCTAAATTCAAAACCTCTTTAGCTCTTGCAGCTCACTTAAAGTTCAAGCACAAACAAAAAGCTTACTTCTGCCTTGTATGCTCAATAACTTTTAAAACATTTGAAGAAGCTAAACGCCATCGATATACTTCAGCTCATCGCATCAAAAGAAAAGAAATATTAATCAGTAAAGGAATACCTGTGAAGAATTTAAGCAAGAAGTGTCCTTACTGTTCTGATAACGTGGTGTTGAGAAGTATTTTGGAGTTGAAGGAACACATTCGTGTTGTGCATCCAGAAATAAAAAAGAGATGTCCTAAATGCGGCATGACCTTCATTCTATTCCAAGAAGTCAGTCGCCACATTCGAAGTAACGCGTGCCAGTTTCAAGACTCCCATCCTCTCGACTCTTCTGTCATGTGGAACTGTAGCCAATGTTTGTACAGCACCGATTCGCAGGCCGAATGCTATTACCACGAGGTTTTGCATACAGAAACAATTAAAGAACATCGGAAAGCTGGAAGCAAAGAAGTCCTGGTGGAAAAGTATCCATGTCCTATCTGCTCTAAGACGTTCAGAAAAAGATATCTTCGTCAGCATTTAAGGTTGCATACTTTTGAAAGGCCTTTCGTGTGCTCAACGTGTGGAGCAAACTTTACTACTCAGTCCAGTCTCTCTAACCATACCAAGACCAGTCATCAAGCACGCGTCACTGCTGATCCAAAAAAGGTTGTAATACCAGTAATACCTTCTTTAAAGGACGACTGGAAATGTAACAGATGCTCGAAAACATTCTCTAATAGGAGTGCTTTGAGTCGCCACGCATGCGATGCTGTCAGACGATGCCCGCATGATAACTGCTCCTACGTTGCTACCACTCCGGCGCATTTAGCCAGGCATAGAACGAGTCATGGTGAAAATATAAAAAATCATGAATGTACCCTTTGTCCTTTTAAGACAAACCAGGCTAGCCACATGGAGAGACATTTGCGTTGCCATAAAGGTGTAAAGCCATACGCTTGTCCACACTGTGATTTTACTTGCGGTAGTTTGGAAAACCTTCGGAAACACGTTCTCAAAAGTGGTCGGCATCCTGGGAAGTTCTTATATCGCTGCCAGTCTTGTACTTTCTGTACCAACACAGCTACTGATTTACGTGCCCATTTAACTACGACTCATGCTGACAATTACGACGCTAAATCAGCAATCCAAGCTGTTAAATATATTTTATTTAAAAATAATGTATAA
- Protein Sequence
- MLSPRDDDDDDSHLCIKCNTTIVGLENYVKHRKQRCGKISKPETSKADISSIDTLDPAYSLGADVFFQSLELQSSVKKTSLSRLTPTLPISKAVLDSKTTLVEASTSRDIPRMSPLETNLREEDWIGGHSLRISGHEDNQTKLINAVASISGTAKKEITRSTYSIAAYNDFKCDEDFDELDESEEEEEEEPHASCIKWKLPPNYTGGKWRPASPDHEDWDMREEQEHTGGKWKPIMGDSNERDDDYDVPPPGHTKGKWVPGHEKTQIMQPTLQSKGSVQYWCGPCNRRLGSRAIYEKHLMSSLHMRKVLPEHELEFSGHLEPISSVKRSLRPSRFTDDSVYVQVQKKAGKELKPKLTVKVEKKKRKRNPTFVHCSGCKSRVRLHLMGKHLISHYHFRKATDIKSESYQQLILGNIDAIVHQSPFQCSPCKFYTNWLPNFMQHWLSDEHNNKTAMLEGRFWCSFCKFDCVTSQDMLEHMSGSEHSEVVAVINRSMPIIIRKKNIIACGTCRKEFKYNVEMRRHFNRTGHKPAYTATDDYQEFHKCRQCSSKFKTSLALAAHLKFKHKQKAYFCLVCSITFKTFEEAKRHRYTSAHRIKRKEILISKGIPVKNLSKKCPYCSDNVVLRSILELKEHIRVVHPEIKKRCPKCGMTFILFQEVSRHIRSNACQFQDSHPLDSSVMWNCSQCLYSTDSQAECYYHEVLHTETIKEHRKAGSKEVLVEKYPCPICSKTFRKRYLRQHLRLHTFERPFVCSTCGANFTTQSSLSNHTKTSHQARVTADPKKVVIPVIPSLKDDWKCNRCSKTFSNRSALSRHACDAVRRCPHDNCSYVATTPAHLARHRTSHGENIKNHECTLCPFKTNQASHMERHLRCHKGVKPYACPHCDFTCGSLENLRKHVLKSGRHPGKFLYRCQSCTFCTNTATDLRAHLTTTHADNYDAKSAIQAVKYILFKNNV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01082029;
- 90% Identity
- -
- 80% Identity
- -