Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 7.3e-05 1.4 10.2 0.9 15 50 83 117 73 123 0.83

2 5 0.15 2.8e+03 -0.4 0.0 24 46 120 142 117 148 0.80

3 5 1.7e-05 0.32 12.2 0.1 22 47 146 171 138 176 0.89

4 5 0.048 8.9e+02 1.1 0.1 25 43 177 195 172 199 0.83

5 5 0.0003 5.5 8.2 0.1 13 51 193 230 184 232 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	7.3e-05	1.4	10.2	0.9	15	50	83	117	73	123	0.83
2	5	0.15	2.8e+03	-0.4	0.0	24	46	120	142	117	148	0.80
3	5	1.7e-05	0.32	12.2	0.1	22	47	146	171	138	176	0.89
4	5	0.048	8.9e+02	1.1	0.1	25	43	177	195	172	199	0.83
5	5	0.0003	5.5	8.2	0.1	13	51	193	230	184	232	0.85

Coding Sequence: atgaacaacgTACCTCCTGGTCTCTCTTTAGTTGCCGAAAATGATCACTTAGTCTTGAAACGCGATTGTGTTCTCGAAGTACAGTATCATTTGGACGAGCAGACATacctttcaaaattcgaaactaTGGGATTGCCGTATCAACACGATTTGCTAAAGCAGTCCGGACGTAAAGTCATGGCAAAAGATTTAATGTTCAGacctgatgatgatgaaaaaAAACCTATGTACCCTATCCCGCATCCACCGAAGTACTCCAACTCCAGCGAGAAACCGTATCAATGCAATACCTGCAAAAAGACGTTTTCGCAACAGTCGAATCTGTGCAAGCACCAGCTTATCCACTTCGGTGTGAAACCGTACGGCTGCGATACGTGCGGTAAACGTTTCACCCAGCAGGCGAATCTGATCAAACACAAACGCATTCATACGGGCGATAAACCTTTTACATGCAAAGTATGTCAGCGACAGTTCTCTCAAAACGCCAACCTCAAGAAACATATGCAGCTGCACACCGGTGAGAAGCGCTACCGTTGTGAATTCTGCGATAAAGCTTTCGTTCAGCAGGCAAATTTGGAACGTCATCGACGTACCCACACTGGTGAAAAGCCGTTTTCGTGTGAAGTTTGTCAGAAGAAATTCACGCAGAAGGGTAACCTTGTGAAGCATGAAGTCATTCATTATCTCAAAGATAACTCGCGACTAGCGTCTCAGTTTCAAACCAAAGTGCCTAGCAAGGAAGTACTTCATAATTTGATTCACGTCGCCGACCTTCCGAGTCAGTCAACATCGAACGATGGTTACCATAAAAAGATGGGAGCTCCGGTGATCGTATCAGCGAGGGAGGGAATGTTCGTTAAACGATTTTGA
Protein Sequence: MNNVPPGLSLVAENDHLVLKRDCVLEVQYHLDEQTYLSKFETMGLPYQHDLLKQSGRKVMAKDLMFRPDDDEKKPMYPIPHPPKYSNSSEKPYQCNTCKKTFSQQSNLCKHQLIHFGVKPYGCDTCGKRFTQQANLIKHKRIHTGDKPFTCKVCQRQFSQNANLKKHMQLHTGEKRYRCEFCDKAFVQQANLERHRRTHTGEKPFSCEVCQKKFTQKGNLVKHEVIHYLKDNSRLASQFQTKVPSKEVLHNLIHVADLPSQSTSNDGYHKKMGAPVIVSAREGMFVKRF

Sequence clustering based on sequence similarity using MMseqs2