Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00065 6.8 8.1 0.0 25 44 71 90 66 94 0.87

2 7 0.028 3e+02 2.8 0.2 21 44 95 118 90 126 0.84

3 7 0.12 1.2e+03 0.9 0.2 21 43 123 145 119 150 0.83

4 7 0.00037 3.9 8.8 0.6 21 43 151 173 143 178 0.82

5 7 0.0022 23 6.4 0.2 18 52 176 211 171 213 0.85

6 7 0.00073 7.6 7.9 0.0 20 44 235 259 228 269 0.78

7 7 0.013 1.3e+02 3.9 0.1 21 43 292 314 275 318 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00065	6.8	8.1	0.0	25	44	71	90	66	94	0.87
2	7	0.028	3e+02	2.8	0.2	21	44	95	118	90	126	0.84
3	7	0.12	1.2e+03	0.9	0.2	21	43	123	145	119	150	0.83
4	7	0.00037	3.9	8.8	0.6	21	43	151	173	143	178	0.82
5	7	0.0022	23	6.4	0.2	18	52	176	211	171	213	0.85
6	7	0.00073	7.6	7.9	0.0	20	44	235	259	228	269	0.78
7	7	0.013	1.3e+02	3.9	0.1	21	43	292	314	275	318	0.89

Coding Sequence: ATGCATAAATTGCAAGCAGCTTATCATTTTCGAACACTCTGTGTACAAACAGATGTAACTTTACGTACTTTTGTCACTAATGTTAGTCAATACACAGGAAGTTATGAACCTATTGACTGGAGTAAAATTCATATGAATCAAGAaggTACAAGAACATACACAGATCCACAAGGAAATCAAATAACAGTACCTATAAAACCGAAAGCAAGCACAAAGTGTGATGTTTGTAGTAAAGTGTTCAGAAAAAGTTCTGATTTAACAAGACATAAAAGAGTTCATAGTGGAGAGAGGCCTTACAAATGTGATATCTGTGATCGTACTTTTAGTCAGCCAGCTCATCTTAAAACCCACAAAAGAGTCCATACTGgtGAACATCCATACATgtgttatatttgtaataaaggATTTGCACATAATTCTGCATTAACACGTCATAAACGAGTTCATAGTGGTGAACGTCCTTATAAATGTcctatatgttttaaattttttgttagtAGTAGTTGTTTATCTAAACACCGTCGTATTCATACAGATGAAAAACCATATCAGTGTGATATTTGTCAGGAGAAGTTTGCTCAGTTGTACAGTcttaaatcacataaaataatgCAACATGGATTTAAAAAACCTTACATCTGTGAACTGTGTAATCAAGGTTTTATATCGAGATTTGCATTTCAAAGACATAAGAGAAAACATACAGGAGAAAAACTGGCAACCTGTCATATTTGTTACAAGAAATTCAGTGATAATACCAGTTTAATGGTACACATGAGAGTTCATACGGATGAAAGGAGATATAAATGTGATATGTGTGATAAAAGATTTCGAGCAAGTTCAGTGTTAGTAAATCATAAACGAGTTCATACAGGAGAAAAACCATTTCATTGCGATATTTGCAGTATGAGATTCAACACACGCAGTAACTTATTAAGGCATAAAAAGAGTCATAAATAG
Protein Sequence: MHKLQAAYHFRTLCVQTDVTLRTFVTNVSQYTGSYEPIDWSKIHMNQEGTRTYTDPQGNQITVPIKPKASTKCDVCSKVFRKSSDLTRHKRVHSGERPYKCDICDRTFSQPAHLKTHKRVHTGEHPYMCYICNKGFAHNSALTRHKRVHSGERPYKCPICFKFFVSSSCLSKHRRIHTDEKPYQCDICQEKFAQLYSLKSHKIMQHGFKKPYICELCNQGFISRFAFQRHKRKHTGEKLATCHICYKKFSDNTSLMVHMRVHTDERRYKCDMCDKRFRASSVLVNHKRVHTGEKPFHCDICSMRFNTRSNLLRHKKSHK

Sequence clustering based on sequence similarity using MMseqs2