Basic Information

Gene Symbol
-
Assembly
GCA_034766995.1
Location
CM068321.1:28602138-28613822[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 31 0.0063 0.89 11.3 2.0 2 23 153 174 152 174 0.98
2 31 0.0011 0.15 13.8 2.7 2 23 181 203 180 203 0.95
3 31 0.0057 0.8 11.5 4.1 1 23 217 239 217 239 0.97
4 31 1.1e-05 0.0016 19.9 1.2 1 23 296 318 296 318 0.98
5 31 0.00035 0.049 15.3 6.4 3 23 326 346 325 346 0.98
6 31 0.00031 0.044 15.4 1.7 2 23 365 387 364 387 0.96
7 31 0.00026 0.037 15.7 8.4 1 23 451 473 451 473 0.97
8 31 0.0058 0.82 11.4 4.2 1 23 479 502 479 502 0.95
9 31 1e-05 0.0014 20.1 1.5 1 23 507 529 507 529 0.98
10 31 4.4e-06 0.00062 21.2 3.6 1 23 542 564 542 564 0.97
11 31 4.4e-07 6.2e-05 24.4 2.1 1 23 571 593 571 593 0.97
12 31 3.3e-06 0.00046 21.6 1.6 3 23 605 625 603 625 0.96
13 31 0.00014 0.019 16.5 4.3 1 23 631 653 631 653 0.99
14 31 2.1e-06 0.00029 22.3 1.8 1 23 659 681 659 681 0.99
15 31 1.6e-07 2.3e-05 25.8 0.5 1 23 687 709 687 709 0.99
16 31 0.00078 0.11 14.2 0.0 1 22 715 736 715 739 0.91
17 31 0.8 1.1e+02 4.7 0.0 8 23 879 894 878 894 0.93
18 31 6.7e-06 0.00094 20.7 2.1 1 23 1020 1042 1020 1042 0.98
19 31 5.5e-05 0.0078 17.8 0.6 1 23 1048 1071 1048 1071 0.95
20 31 0.0035 0.49 12.1 1.0 3 21 1091 1109 1089 1110 0.94
21 31 1.3e-06 0.00019 22.9 1.6 1 23 1118 1140 1118 1140 0.96
22 31 0.0021 0.29 12.8 3.7 1 21 1146 1166 1146 1168 0.94
23 31 0.00027 0.039 15.6 1.0 5 23 1178 1196 1174 1196 0.93
24 31 6.6e-07 9.2e-05 23.8 0.2 1 23 1202 1224 1202 1224 0.99
25 31 2.9e-05 0.004 18.7 1.6 1 23 1363 1385 1363 1385 0.97
26 31 1.4e-06 0.00019 22.8 3.1 1 23 1398 1420 1398 1420 0.98
27 31 0.00033 0.046 15.4 0.6 1 23 1426 1448 1426 1448 0.95
28 31 2.9e-06 0.0004 21.8 0.6 1 23 1454 1476 1454 1476 0.98
29 31 1.7e-05 0.0023 19.4 3.1 1 23 1482 1504 1482 1504 0.97
30 31 3.8e-07 5.3e-05 24.6 0.1 1 23 1510 1532 1510 1532 0.99
31 31 0.0016 0.22 13.2 0.9 1 23 1538 1561 1538 1561 0.96

Sequence Information

Coding Sequence
atggaagaaacagaaaaaaatgttcttccAATTACGTTGGAAAAAGTTTGTAGATCGTGTATGAACGAAAGGACTGATATGCGATCAGTTTTTAGTGAATTAGAAATTGCAGGACAACAAGCGCAAGTTTCACAAATCCTCATGGCGTGTGCGTCTGTGCagGTAATAACAGGTGATGGATTGCCTGGGTTAATTTGTCAGCCATGCGTCCATCTGTTAAGTAATGCGTATTCATTTAAACGACAATGTGAAAGTTCTGATACAAAGCTGCGCCAATATGTAAACTTAGAGTTCCCGGATATAAAAGAAGAACGAGAATCTGAGACATTAAACATTGTCGTTAAACCTGATATCGACGTCATGTCAGAAATAATGTTAGAAGATAATTCACCGTACGATGATTCTGATGCAGAAAGTAAcgataaattggaaaaaaatgataaattagttCCAAATCAgtgtaaattttgttttaagaaaTTAGCATCCAAACAAGGTTTAAGCATTCACATGAGAAAGCACACAGGACAAAATATGAAGGTGTGTCCAATTTGTCATGCAggttttacaaaaacaaatcatttgaaAAGGCATTTGCAACAGGTGCATACGAAAAAAGAACCAGACAATAATACTGAAACCAAAATACATGTATGCACagtttgtaatgaaaaattcgATAAAGTTACACATCTTATAAAACACAAACGTTTACATAGATTGtctaaaagtaatgaaaaaactGATGATGAAAAATCAACAGATCAGCAGCTAGTTAAATCAGAAATAGAAATTGAACGAGATGAAAATAATGACAACGATAAAGACagtatatctaataaaaaagatttggaTTATGTTCAACCAGGGAAGATTAAAGGAAAATTTGAATGTAAAGAATGTCATAAGATTCTTACAACTCCAAATGGATTACAAATACATATGCGTAGGCATACAGGCCATAATTTAGTATTGTGTTGTgtatgtaataaatcatttactaaAACAAGTCATCTTAAACGGCATTTAGCCACTCATGGCACACCCACAGAAGAAGTACGAGCTGAAATAAAGCCATCAAAATTAAGTTTACCATGTGAATTTTGTGATCGTAAATTTGTGTATCGTAAAAGCTTTGTACATCACATGCGAATTGAACATGGTATTTCAGATGatgaaaatattccattaaGTTCTTATGTTAAAACAGAGAAAAAAGAGCTTGATAATGAAGATGACCAAAATGTAAATGCTGAAGGAGAAATAAAGAGCAATGATGAGGGAGGATCTGATCATGATGAACCATATCATGAAGAAATAGATGAAAAAACAGgtgataaaaaaaaagtgttcgAATGCCATGTATGTCAGCATAAGTTTACAAGATCGAATCATTTAACTCGTCATATGACTTTACATAGAAACGTATTAACACATAAATGTGACCGATGCGAAAAGTCATTTTTAACAGAAGAACATTTACAGAAACATATACAGGAATATCATATTGATCGACCGTATATTTGTACAACGTGCAATAAACCATTTACCCGAGGAGAGCATCTTATACGTCACCTTAAAGTACATGATAAAGAAAAGAAAGATGATAATACAGTTATAGAACATAAATGCTCTGTATgtgataaagtatttataagaagTGATCATTTAGCCAGACATACTAAACTTCATTTGCTCAAAGATAAGAGACATGTATGTGATGTTTGTAACAAATCATTTAATCGTTTGGACAATTTACGTACTCATCAACGCGTTCATACAGGTCAAAGAGATCCAGTAAGACTTCACCTATGTGTATATTGTGGAAAAGAATTCAATAATTCTAGTAATATgATTGTTCATATGAGAAGACACACAGGAGAGCGGCCATATAAATGTAATGTGTGCGGAAAAGGTTTTCCACGTTCTCACGATCTTAAATGCCATGAACGAACACATTCTGGTGAACGACCTTATCAATGTTCATTATGTgggaaatcatttaataaaagtaacaaaTTGgTTCGACATACTCGTGTTCACACTGGTGAAAGGCcttatgtatgtaatttatgtgGTCGAGCTTTCACTCAGTCTAATGATTTAACATTGCATATGAGACGGCACACAGGGTCTAGACCGTATGCATGTGGAGTTTGTCCTGCTCGGTTTATTCAATCTGGTCAACTTAAAGCACATAGAAGAGCTCAAGAACATTGGGTAGAACAAGAAGTTCAATTCAGAGGTAATAGAGTGGAACCTGTACACATAGAAGGATTTGTTGAAACTCCCATCAAGCACAGAAATCGTGTTAAACCTATAAAACAGGAAATGAATGCTGTTCCTGAACCATTCACAGATAATCCATTTTTAGCTGTAAGTGCTAATGGTAGTGCTGCTGCAGTTGTTCGATCTTTTGTCAGAAGCAATAGAGACGATGTTGATGTAAAACCAACAGTTGAAGAAGCAGAAGAATACCAAAGTACAAGTACATCATTTCAACAAACCAGTATTGTGACTTCTGTTGCCGGTTCATTTTCTACTAGTGAAAACTTTAATTTCCAACAATACGATTCAATACCAGAAACCCCATCAAATTTTGCAGAAATGCTAATGGAATGTGCTTCTGTACAGGAAAGCTTCAATCGAGAAGATAGCTTGGAAGTTCATATTGCTTCTCATGATTCAAATGTAGACATTAAACCTATGTTAGATTCtttagaaaatatagaaaattatattcgtGTCGAAGATTATGCTGAtactttaatagaaaaaaattacttagaACCCCAAGTAAGCATATTTGAACAAGATAGTGACTTTGAAAAGGAtgatagttttgaaaataaagaaccAATActgataaatgaaacaaaaggAGATTCGATTATAAATGTAAGTAATATCAAGCCAGAAGCAGAATTTGaggaaaaatgtgatttatctGATACTTTACAAATTCCATCTGATACAGATAGTAAAGatgagaatgaatttaattctGATGTACCTCAAAAACGCAAACGTGGTAGACCAAGAAAAGAACACAAACCATATAGTTGTGATATTTGTACGAAATCATTTGCAAGAAAAGATCATATGATTCGCCATGTAAAACTTCAttcgtttgaaaaaaagtatgaatgtGATGTTTGTAAGCGTATGTTTTCTAGGGAAGAATTATTGAATAAACACAAAGCTGTTAAACATGAAAAATATCGTGATACTCATATGAAAGCACataaagaaaaagataaaatggTACATTGTAAAACTTGTGACAGGCATTTTGAAACTAGAGCGGAATTAGTTAATCATTTGAAGTTGACAAATGATTGTTCTCGCCGCTTTTTATGTTCAGAATGTGGgcaaagatttacaaaaaaagattatttacaaGTGCATATGCGTAGGCACCGTGGAGAAAAACCTTTTAAGTGTAAATATTGTGAGAAAgGTTTTCCACGCACTACTGATTTAAAAGCTCATGAAAAATGTCATACtggagaaaaaaatcatttatgtataGTATGTGGAAAAGGATTCGGCAGaGCTTATAAATTGACATTACATATGCGTACGCATACCGGTGAGAAACCTTATCAGTGCACTTATTGTGATGCAGCATTTGCTCAGAGTAATGATTTAAAAGCACATATTCGTAGACATACTGGTGAACGCTATCATTGTGATCTATGCACTGACGCCTTTTTGATGGGTTACATGCTTACTCAACATAAAAGAAATGTTCATGGTATTGAAGTTGCAACTTCACAACGTCCTATTGCGCGACTTCAACCATCTGTTTATAACATATCAGTTGTTAAACCAGAAACATTAAAAGCTCCAAGTACGGCAGCAACATTAGACCCTCGTCCTGTACAAACAAATGATGGTTTACCAGATTTGATTTGTTTAACTTGTATAAAAGAACTTCAAACAGCATATGTTTTTAAGTTACGTTCAGAAAAAACTGATTCAACATTACGACAGTATTTGAATAAAGATTATGAAACACATTTACTTTCATCAAAATCTGATAGTCTTGCTGAACATTTGAGAAGACATAAAGGTATCAAACCTCATCAATGTGAAGAATGTTCTAAACGATTTGTTAGTTTAAGTTCCCTTAAAGCCCACAAATTAATTCATGAACGAGATAATGGAAAAATGGCACAAGAGAAAAGACACCAATGTTCTTATTGTCAGAAgagttttgtttcaaattccAGTCTTATTATTCATACTAGAACTCACACAAAAGAGAAACCTTTTTTATGTACATCATGTGGTAAAAAATTTGCAACACAAGGTGGCCTTGATTTACATACACGTCGACATACTGGTGAACGACCATATAAGTGTGAGTTTTGTGGGCATGCCTTTGCTGAAAGTAGTAATTTACGAGTTCATATTCGTGGTCATACAGGAGATAAACCTCATATGTGTAGTTTATGTGGAAAAAGATTTAcacgaatgtttttattacagcTACACATTCGTACTCATACCggtGAAAAACCATATAAATGCACTGAATGTCCGAAGGCATTTGCTCAACAAGGTGATTTAGCTGCTCATAAACGAACACATTCAGGATATAGACCACATGTATGTGTTTATTGTGGTCAAGGTTTTATTAAAAGTGGTGGAATGAAAAAACACCTTCAATCAAAACATCGTTCTGAAATAAATGTCATCAAAACTAAAACTGAAGATGAGTAA
Protein Sequence
MEETEKNVLPITLEKVCRSCMNERTDMRSVFSELEIAGQQAQVSQILMACASVQVITGDGLPGLICQPCVHLLSNAYSFKRQCESSDTKLRQYVNLEFPDIKEERESETLNIVVKPDIDVMSEIMLEDNSPYDDSDAESNDKLEKNDKLVPNQCKFCFKKLASKQGLSIHMRKHTGQNMKVCPICHAGFTKTNHLKRHLQQVHTKKEPDNNTETKIHVCTVCNEKFDKVTHLIKHKRLHRLSKSNEKTDDEKSTDQQLVKSEIEIERDENNDNDKDSISNKKDLDYVQPGKIKGKFECKECHKILTTPNGLQIHMRRHTGHNLVLCCVCNKSFTKTSHLKRHLATHGTPTEEVRAEIKPSKLSLPCEFCDRKFVYRKSFVHHMRIEHGISDDENIPLSSYVKTEKKELDNEDDQNVNAEGEIKSNDEGGSDHDEPYHEEIDEKTGDKKKVFECHVCQHKFTRSNHLTRHMTLHRNVLTHKCDRCEKSFLTEEHLQKHIQEYHIDRPYICTTCNKPFTRGEHLIRHLKVHDKEKKDDNTVIEHKCSVCDKVFIRSDHLARHTKLHLLKDKRHVCDVCNKSFNRLDNLRTHQRVHTGQRDPVRLHLCVYCGKEFNNSSNMIVHMRRHTGERPYKCNVCGKGFPRSHDLKCHERTHSGERPYQCSLCGKSFNKSNKLVRHTRVHTGERPYVCNLCGRAFTQSNDLTLHMRRHTGSRPYACGVCPARFIQSGQLKAHRRAQEHWVEQEVQFRGNRVEPVHIEGFVETPIKHRNRVKPIKQEMNAVPEPFTDNPFLAVSANGSAAAVVRSFVRSNRDDVDVKPTVEEAEEYQSTSTSFQQTSIVTSVAGSFSTSENFNFQQYDSIPETPSNFAEMLMECASVQESFNREDSLEVHIASHDSNVDIKPMLDSLENIENYIRVEDYADTLIEKNYLEPQVSIFEQDSDFEKDDSFENKEPILINETKGDSIINVSNIKPEAEFEEKCDLSDTLQIPSDTDSKDENEFNSDVPQKRKRGRPRKEHKPYSCDICTKSFARKDHMIRHVKLHSFEKKYECDVCKRMFSREELLNKHKAVKHEKYRDTHMKAHKEKDKMVHCKTCDRHFETRAELVNHLKLTNDCSRRFLCSECGQRFTKKDYLQVHMRRHRGEKPFKCKYCEKGFPRTTDLKAHEKCHTGEKNHLCIVCGKGFGRAYKLTLHMRTHTGEKPYQCTYCDAAFAQSNDLKAHIRRHTGERYHCDLCTDAFLMGYMLTQHKRNVHGIEVATSQRPIARLQPSVYNISVVKPETLKAPSTAATLDPRPVQTNDGLPDLICLTCIKELQTAYVFKLRSEKTDSTLRQYLNKDYETHLLSSKSDSLAEHLRRHKGIKPHQCEECSKRFVSLSSLKAHKLIHERDNGKMAQEKRHQCSYCQKSFVSNSSLIIHTRTHTKEKPFLCTSCGKKFATQGGLDLHTRRHTGERPYKCEFCGHAFAESSNLRVHIRGHTGDKPHMCSLCGKRFTRMFLLQLHIRTHTGEKPYKCTECPKAFAQQGDLAAHKRTHSGYRPHVCVYCGQGFIKSGGMKKHLQSKHRSEINVIKTKTEDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01050519;
90% Identity
-
80% Identity
-