TSC22


Domain
TSC22 domain
Group
Basic Domians group
PFAM
PF01166
Desciption
These proteins are highly similar in a region of about 50 residues that include a conserved leucine-zipper domain most probably involved in homo- or hetero-dimerisation. Drosophila protein bunched [1] (gene bun) (also known as shortsighted), a probable transcription factor required for peripheral nervous system morphogenesis, eye development and oogenesis.
Rederence
  • Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity. Kester HA, Blanchetot C, den Hertog J, van der Saag PT, van der Burg B. J Biol Chem 274, 27439-47, (1999).

Statistic of Transcription Factors




Transcription Factor Table

Species


Gene ID Insect Gene Name Gene Symbol