DM
- Domain
- DM domain
- Group
- Zinc-Coordinating Group
- PFAM
- PF00751
- Desciption
- The DM domain is named after dsx and mab-3 [2]. dsx contains a single amino-terminal DM domain, whereas mab-3 contains two amino-terminal domains. The DM domain has a pattern of conserved zinc chelating residues C2H2C4 [1]. The dsx DM domain has been shown to dimerise and bind palindromic DNA [3].
- Rederence
-
- The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain. Erdman SE, Burtis KC. EMBO J. 12, 527-35, (1993).
- Evidence for evolutionary conservation of sex-determining genes. Raymond CS, Shamu CE, Shen MM, Seifert KJ, Hirsch B, Hodgkin J, Zarkower D. Nature 391, 691-5, (1998).
- Functional and genetic characterization of the oligomerization and DNA binding properties of the Drosophila doublesex proteins. Erdman SE, Chen HJ, Burtis KC. Genetics 144, 1639-52, (1996).
Statistic of Transcription Factors
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Transcription Factor Table
| Gene ID | Insect | Gene Name | Gene Symbol |
|---|---|---|---|
| iTF_00000382 | Abrostola tripartita | Atri005808.1 | dmrta2 |
| iTF_00000383 | Abrostola tripartita | Atri011529.1 | LIG4 |
| iTF_00000384 | Abrostola tripartita | Atri018515.1 | dmd-4 |
| iTF_00000385 | Abrostola tripartita | Atri022195.1 | dsx |