RHD


Domain
RHD domain
Group
Beta-Scaffold Factors
PFAM
PF00554
Desciption
Proteins containing the Rel homology domain (RHD) are eukaryotic transcription factors. The RHD is composed of two structural domains. This is the N-terminal DNA-binding domain that is similar to that found in P53. The C-terminal domain has an immunoglobulin-like fold (See PF16179) that functions as a dimerisation domain [1-2].
Rederence
  • X-ray structure of a NF-kappaB p50/RelB/DNA complex reveals assembly of multiple dimers on tandem kappaB sites. Moorthy AK, Huang DB, Wang VY, Vu D, Ghosh G. J. Mol. Biol. 373, 723-34, (2007).
  • Structure of the NF-kappa B p50 homodimer bound to DNA. Muller CW, Rey FA, Sodeoka M, Verdine GL, Harrison SC. Nature 373, 311-7, (1995).

Statistic of Transcription Factors




Transcription Factor Table

Species


Gene ID Insect Gene Name Gene Symbol
iTF_00000087 Abrostola tripartita Atri016178.1 Rel
iTF_00000088 Abrostola tripartita Atri020910.1 dl
iTF_00000089 Abrostola tripartita Atri010554.1 NFAT5