Basic Information

Gene Symbol
-
Assembly
GCA_907165275.1
Location
OU015649.1:4771309-4778666[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 2.3 1.7e+02 3.5 0.7 1 23 50 73 50 73 0.94
2 20 0.68 50 5.2 3.9 1 23 80 103 80 103 0.97
3 20 0.00081 0.06 14.4 0.8 2 23 186 207 185 207 0.97
4 20 1.4 1e+02 4.2 1.4 1 23 213 235 213 236 0.94
5 20 0.22 16 6.7 4.7 2 22 473 493 472 493 0.96
6 20 8.3 6.1e+02 1.8 1.4 1 22 592 613 592 614 0.77
7 20 0.51 37 5.6 0.4 2 23 748 769 747 769 0.96
8 20 0.3 22 6.3 0.6 2 23 848 869 847 869 0.96
9 20 0.29 21 6.4 2.2 1 23 877 899 877 899 0.95
10 20 0.1 7.4 7.8 3.6 1 23 937 959 937 959 0.95
11 20 0.00068 0.05 14.6 5.1 1 23 967 989 967 989 0.99
12 20 0.97 72 4.7 2.3 1 23 1074 1096 1074 1096 0.98
13 20 0.079 5.8 8.1 1.6 1 19 1152 1170 1152 1174 0.91
14 20 0.33 24 6.2 0.1 2 23 1181 1202 1180 1202 0.96
15 20 0.71 52 5.1 0.4 1 23 1268 1290 1268 1290 0.94
16 20 0.00011 0.0081 17.1 1.0 1 23 1296 1318 1296 1318 0.96
17 20 0.0072 0.53 11.4 2.6 1 23 1408 1430 1408 1430 0.97
18 20 0.00018 0.013 16.4 1.4 1 23 1436 1458 1436 1458 0.99
19 20 4.4 3.2e+02 2.6 2.9 1 23 1549 1571 1549 1571 0.94
20 20 0.00068 0.05 14.6 2.6 1 23 1582 1604 1582 1604 0.98

Sequence Information

Coding Sequence
ATGTCATCGCCGACGAGCACGTTAGCCGACCCAGTCGCGTCTATAGTGCGCCCGTTGGAAGGCCGCATTAGCGGCGAAGTTTCTTCTGGCGCCTCCTCGGACGCCACTGAAGATTTTGAACTACCGCAGTGCAAAATTAAGCGAAATTACAATTGCCCCAAGTGTACGTTCTATACGCAGAATCCTCGTGCTTATTTATTGCACACGCGCGACGTTCACTTTGAAAAAATTAAAATTTATGATTGTTCTTTCTGCGTGTACGCGTCGAAGCATTGCCAGAAACTTGTGAGACACATAAAAATGGTTCACAATGAATCTCCGGCGGCCGTCAGCGAACCCGATACGAAGTTATCTAATCCCGCCGCATCGGAAACTTCGGAGCAGATAGATGATATGGTCGAAGAAATCGAAGATTGTGATGAACAAGTCATGGATCTAGTTACTAATGTGGCCAAAGACAAGAGCAAATATTTCTGTTGCGACAAGTGCAATTATGTCACTCACATTAGAGCAAGATATACAAAACATGTCAAATATCATTCCACACCGATGATAAAGTGTACGATATGTGATTTCCGGACACCCTATAAGTGGAATTTGGATCGCCACATGAAGAACCACGGAGGCACCGGCAGCTTCAGTTGTTCGATGTGCAACTTCACAGCGGATATTAAGCAAAGTTTGACTGTGCACGAGATGAATCACCACGCGCCCACCGTGGGTCAATCGTGTTCGAATCGTCGACGGAACCGAGTGGGCGCTAGCGACACATCTGTCGCTCGTGCCGAGAGCGCGATGCACGTGAAGGAGGACGAAGGGAGCGGGGACTCGCGCTCTTCGTGCACAGCCTCGGATATGGGACTTCATGACGCGGACATTGAAATGATTACCTGCAATAGTGAATCCAATGACGCTTCCGATGATGCAATCAAAAATGATGATTCTCAAGATTACCACAATCAGCAAACACTGAATAATAGCTCATCAGATGAATCCAGATCTAATAAACAAAGCAGAAAAATATCCAGGCCTATACCACAGCTGATACCTTTAAATGCATCAACACCAAATCAAAACAAAATAAATACGGGTGAACCTCCAAAGAAAAAACTTAAAGAGAACCCGGAATCTTTAGATCTGACCGTCGAAAATAAATCAGATGTGCCTCAGAGTGATATAACATTTACACCTTCAAATAATTTGCCAAAAGAACCAGTAGTACGAAAGAAGAATGAGTCATTTTTTGATCGACTAAAAGAAAGACTTCTTACAGAAACAGGGGATGAGGGTTCCTTGGTATGTAAAAATTGTAAGTTTGAAAGCAAATGTTTATCGGAATATACGGTACATGAGAAAAATTGCACATCTCAAATTAATCGGATTACACCGAACCCGTCGTACCCATTAAGTTCAACTCGATGCCAGAACTGCAGACATAGGTGTAAATCTAGCGCTGATCTGTTTAATCACTTGCGTACATGTAAAAAAAACAATGAAACAGAATCAGTCATACCTAAAACTTCACAAAATCAAAACAACCATGATTCGAGTATTACTCAAGAAAAAGAAACTGAACCTCATCCTATGGAAAATGTTGTGTTTGTTTGGAATAATATAAATCGAGAAAATAGTAAGTTCAATACACCACTGGACATTAATATAAACGATGATTCTACCCTTCCTGAAGTGAATAAAAGTTTTGATTCTGAAATCACAGATGCAGATAATGATGGCATGAATTTGTCACCGAGTCACGCAATGGGCAAAAAAGTATTTAAATGTCCACATTGTCAGTTTTGGGCATCTTCTGCTTCACGTTTTCACGTACACATTGTGGGGCATTTAAACAAAAAGCCATTTGAATGTTCACTGTGTAAATATAGGTCAAATTGGCGATGGGACATTACCAAACATATAAAACTGAAATCTGCTAGAGATCCGGAACATAATGAAGCAAAAGTCTTGATGACCGATGAAACAGGACGTAGAAACTATAGTAAATACAATAAGTTTTTAGCTATATCAATTTTAAATGAAAGTGGAGAGAACGAATTTCATTATGTAGACCCAAATACATCGGTAGATGCGATGATGGAAGTGGACGAATCGATTGATGATAATCAGATTTCTGTATGTGATGTGCAGCCACTGAATCTACAAACACAAAACAATGATCAAAAATATGATTCAACAATGGAAAATAGAACTGACGATATGCGGAAACCGAAAAAGACATTTTGGAAATGCAAAAAATGTAATTACAAAGATCCATCAAAAGAAGCATTACTAGAACATGTCCGAAATCATTCAAAAGCGGATGGCGGGCAGGAAGATATAAAGTCAAATAACAAAAAGTTGGAGAGTACCACCGACCCAGCCGATTTGGCGTACCGTTGCGGACATTGCAATCAACTATCTAACTGGAAACATGTGATACAAAGACATTGTCGTCTGAAGCATGATGGCGTGATAAAAGTAATAACTACAGTGAAACCGAAGGGAGAACCTGGATCGCAATCCTTGAATGAAATAATCAGTGATACTTGTAGCAAGTGTCCATTTAAAGCAGATGACAAGAAAACGCTTTTAGAACACTTGCAACAGCACCAGCCTTCACCAGAATCTATATTCAAATGCTATTTTTGTCCATTTTTTGTCAAAAATGAACACGAGTTAATGCAACATTTAGTATTGCATGGAATTAATGATCCAGAAGACTACATTGCTAAAGCGATGGGATGCAAATCCCCGCTTCCCGATCAAACATCAAGTAATGCAGTTGTTGCAAATTCATCTTCTACTAAAAGACACAAATGCACCGAATGTCCATATGAAACAAACAGCAAATCCCAATTTATGTATCACGAACAATTTCACCGTCTTCCAGCCGATACTCCATATAAATGTCAGGTGTGCAACTATAGTGTGTCCAAACGACACTTGCTCCATCAACACATGCGGGTTCATGGAATCTTTCCAAAGAAATTTGAATCGGACACTGACGTGGATGCACCACCATCGCAACCCTTTAAAGCTGAAATAAAAATGGAATCAACCGTTAATATCGACGAAATCCCCTATGTTTGGGTATCAGCAAAAAACGAATTTCACAAAATGTACAAATGCCGCTACTGTTCTTATGTTAACTCGCAAAAAAATAAAATTCCATATCACGAGAAGATACATTTTATAAATTTCGAAAACAGTGAAATAACTATATACAAATGTCTGGAATGTAAGTTTACATGTGACAATGCATTACGATTAGCTGAGCATTCTAAAACGCATGGTGAAATATACGGACGCATATACTGTCCTGTCGAAGAGGACATTCCTGACGATGAACAAATTTCTAAGTTAAGGAAGGTGATTGAAAATGAAAAAATATGCATTGCTGAGGATATGCCTAAAGAAGATTGGGGATTGAAAGACGTGGAAGCCGTCAAAACATTGTACTTCTGCCAAAAGTGTCCAGCTAGATTCTTTACTGAAAGTGACTTAAAGCTGCATGATAAAAATCACGATTTATCTTTACCAAACAAATGCAAAAGTTGTGAATTTTCAGTCCCCTCAGAAAGTGATTTAATTGAGCATGTTTTCGTCCATTCTGATGAGCATCAGACAAAAACTAAAATGTTAAAATTCATGCATAATTCACACCCTGCTCACAAAGAACCTAGATTAGAATTAATACATTGTCAAACTACGTCAGAGATTACCTGGGTAGTATCTCACCCCAGCAAAAATTTCCAGCTAGCGGATTCCATTAAGAAAACGGAGATAAGGCACGTGCCAAAACAATATTTTTGCCAGGAATGTCCTGCAAAATTCTTAAAAAGCTCTGCACTCAGCTATCATGTAAGTTTACATGGAGCTGATGGCGATTATAAATGTAAAAAGTGTAATTATTCTGTCAAGAACTCTGGCAACTTAGCGAAGCATGAATTGTTACACGAAAATGATGGAAAAACTTCTAATTGTGATTACGAATCTGGTGAAGACTTGGATTACAAAAACGTTCCGTTGTCGGGTACAGATTTATTCCAACGAAAGACCGAAGCACAAAAAAGAGTTTTAAATGGCAAAGACAAATTAGTAAAACCAAATGACCATTTTCCTCCTGTACTTCAGGCTGACCCACAGTTTGGTTATTTGATGCACGGTAACCCAGAATTTATCTACCCAACTTATTTAAAAAATGGCCGACAGAAAGAGAAACGATATAAATGCCACAAATGTCCCTCCGCATTTGAAAAAAGAGAACAATACAAAATACACCTTTCTTTGCACGGATCAAAACAAAGATATAAGTGTGAGCTTTGCGATTACTCTGTCAAGTACTATGCTAATTACGTCCAACACATGCGAAAACACCAGATGAACGACGAAGCTCAAGCCGAAAGAAAAAAATGTAGTAACGAATTTAACGAACCTGCCAGTCAAGACAACAAAGAAGATGAAAGTCCAGACAATATTAAGCTTGCAATTAAAACGATGCCCAAACCGCCACCGCGAAGTGATTTTCAGCAATTTTCAATAAGCGACCAGCAAACACTGCGATTGCTGCAACGTAGACGTTCTGCTAATAATGCTGAAAAAGAAACTAATCCATCGGAACAGTCAACCACCAAAGAACGTAAGCTCCACATGTGTTTATTTTGTCCTTTCACTAACCAGCGGCAAGACGCTTTAAGTAACCACCGCAGAAGGCACAACGACGAAGACGTCCTCAACGTTGGCCACCATAGATGCCCCTATTGTGACCTATCGGTGGTACAGTCACATTTCTTACGCGATCACATTAAGATGCACTTTAGTTATCAGAAAACACTTATCCCCGAATGTTTCTTAGCAAGTGAAGAGTTTGTTAGTTTTAAAATTACAAAATTAGATGATGAAAATACGTCAGAAGATCTCATTTTGGTTGAAAAAGATATTTATAAATGTAATGAAGACAAAATGTTTGTCAATATTAAAACCGGAGAAGTTAAAGTTGAATAG
Protein Sequence
MSSPTSTLADPVASIVRPLEGRISGEVSSGASSDATEDFELPQCKIKRNYNCPKCTFYTQNPRAYLLHTRDVHFEKIKIYDCSFCVYASKHCQKLVRHIKMVHNESPAAVSEPDTKLSNPAASETSEQIDDMVEEIEDCDEQVMDLVTNVAKDKSKYFCCDKCNYVTHIRARYTKHVKYHSTPMIKCTICDFRTPYKWNLDRHMKNHGGTGSFSCSMCNFTADIKQSLTVHEMNHHAPTVGQSCSNRRRNRVGASDTSVARAESAMHVKEDEGSGDSRSSCTASDMGLHDADIEMITCNSESNDASDDAIKNDDSQDYHNQQTLNNSSSDESRSNKQSRKISRPIPQLIPLNASTPNQNKINTGEPPKKKLKENPESLDLTVENKSDVPQSDITFTPSNNLPKEPVVRKKNESFFDRLKERLLTETGDEGSLVCKNCKFESKCLSEYTVHEKNCTSQINRITPNPSYPLSSTRCQNCRHRCKSSADLFNHLRTCKKNNETESVIPKTSQNQNNHDSSITQEKETEPHPMENVVFVWNNINRENSKFNTPLDININDDSTLPEVNKSFDSEITDADNDGMNLSPSHAMGKKVFKCPHCQFWASSASRFHVHIVGHLNKKPFECSLCKYRSNWRWDITKHIKLKSARDPEHNEAKVLMTDETGRRNYSKYNKFLAISILNESGENEFHYVDPNTSVDAMMEVDESIDDNQISVCDVQPLNLQTQNNDQKYDSTMENRTDDMRKPKKTFWKCKKCNYKDPSKEALLEHVRNHSKADGGQEDIKSNNKKLESTTDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGVIKVITTVKPKGEPGSQSLNEIISDTCSKCPFKADDKKTLLEHLQQHQPSPESIFKCYFCPFFVKNEHELMQHLVLHGINDPEDYIAKAMGCKSPLPDQTSSNAVVANSSSTKRHKCTECPYETNSKSQFMYHEQFHRLPADTPYKCQVCNYSVSKRHLLHQHMRVHGIFPKKFESDTDVDAPPSQPFKAEIKMESTVNIDEIPYVWVSAKNEFHKMYKCRYCSYVNSQKNKIPYHEKIHFINFENSEITIYKCLECKFTCDNALRLAEHSKTHGEIYGRIYCPVEEDIPDDEQISKLRKVIENEKICIAEDMPKEDWGLKDVEAVKTLYFCQKCPARFFTESDLKLHDKNHDLSLPNKCKSCEFSVPSESDLIEHVFVHSDEHQTKTKMLKFMHNSHPAHKEPRLELIHCQTTSEITWVVSHPSKNFQLADSIKKTEIRHVPKQYFCQECPAKFLKSSALSYHVSLHGADGDYKCKKCNYSVKNSGNLAKHELLHENDGKTSNCDYESGEDLDYKNVPLSGTDLFQRKTEAQKRVLNGKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKCSNEFNEPASQDNKEDESPDNIKLAIKTMPKPPPRSDFQQFSISDQQTLRLLQRRRSANNAEKETNPSEQSTTKERKLHMCLFCPFTNQRQDALSNHRRRHNDEDVLNVGHHRCPYCDLSVVQSHFLRDHIKMHFSYQKTLIPECFLASEEFVSFKITKLDDENTSEDLILVEKDIYKCNEDKMFVNIKTGEVKVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-