Basic Information

Insect: Zygaena filipendulae
Gene Symbol: zfh1
Assembly: GCA_907165275.1
Location: OU015657.1:13480669-13486752[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.027 2 9.6 0.4 1 23 64 86 64 86 0.97

2 8 5.1e-05 0.0038 18.2 3.5 1 23 97 119 97 119 0.98

3 8 1.3e-06 9.3e-05 23.2 6.1 1 23 128 150 128 150 0.99

4 8 0.00013 0.0097 16.9 1.0 1 21 156 176 156 177 0.95

5 8 0.0089 0.66 11.1 0.8 1 20 442 461 442 463 0.93

6 8 9.8e-06 0.00073 20.4 1.1 1 23 767 789 767 789 0.94

7 8 6.1e-05 0.0045 17.9 7.2 1 23 795 817 795 817 0.98

8 8 0.0035 0.26 12.4 4.5 1 21 823 843 823 844 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.027	2	9.6	0.4	1	23	64	86	64	86	0.97
2	8	5.1e-05	0.0038	18.2	3.5	1	23	97	119	97	119	0.98
3	8	1.3e-06	9.3e-05	23.2	6.1	1	23	128	150	128	150	0.99
4	8	0.00013	0.0097	16.9	1.0	1	21	156	176	156	177	0.95
5	8	0.0089	0.66	11.1	0.8	1	20	442	461	442	463	0.93
6	8	9.8e-06	0.00073	20.4	1.1	1	23	767	789	767	789	0.94
7	8	6.1e-05	0.0045	17.9	7.2	1	23	795	817	795	817	0.98
8	8	0.0035	0.26	12.4	4.5	1	21	823	843	823	844	0.96

Sequence Information

Coding Sequence: ATGAAGATCCACTCACAACTACCTAACATAACTGTTATCAATATCTCCACCTGCGAAAAATTACTAACCATCGAGCATTGCACCGCGCACATACTAGTCCGGCCCGTGGCTGGCAGCGGACCGGGCGGGGAGGTCAAGCCCGAGGAGGAGGAGGACCGCGGCGGCTCCCCGCTGGGCCCCGGCGGCCCCTACAGCTGCAGCCAGTGCCGCGGGGCCTACCCCACGCGCGAGCAGCTCGACCGACACGAGAAGCTGCACTCGCCCAACACACAGGTGGATACTGTCAAATATACATGCATGAAATGCCACAAGAGCTTCGCGAACGTGTACCGCCTGCAGCGGCACATGATCAGCCACGACGAGAGTGCGAACCTGCGCAAGTACAAGTGCAACGACTGCGACAAGGCGTTCAAGTTCAAACACCACCTCAAAGAGCACCTGCGCATCCACAGCGGTGAGAAGCCCTTCGAGTGCGCCAACTGCGGGAAGAAGTTCTCGCACTCCGGCTCCTACTCCAGCCACATGACCTCCAAGAAGTGTCTCGTGATGAACTTGAAAATGGGAAGAATAAAACCGAATAACCCCGCGCTCAACCCGGATCGAAGTCCTGCCAGAAAACGAAACAATGCCCTGGTCGCATCGCAACTCAACAATAACATGCCATCCAATGGAAATACATTTCCACATTTCCAGCCCATTCTAAATCCTAAATATAACGATGCCGCCGCCTACCTGGCCGCCATATCCTCCCCAGAAAGTAACTTTCATCACCCTCCTCTAGTTCAGCCAGGGATGGCTCCATTTTATTTACCCCCAAGTATGCCAATGGGTCCAGCCAGCGGAATGGCACCTTATAGCATTCCGCCGTCTTGGAGACAACTTTTTGAACATATAGCAGCTCAACAATATCAAGAACGAAAACCTGACGATTATGTTAGTCCAAATCTTAACAATTCTCATACAGATCCTGAAGACATGATCGAAGAAGTCACCGAAGAGGATGACAAAAGGTCAGAAGGAAGCGCAGAGCTCGTTATGGATATAGAAGACGAAGCTGTATCTATAAAAAAAGAACAAGATGAACGAGAAAATGATCCGAGGTCGTCACCTCGTCATTTCGATTCCGTCCCCTTAAATAATAATAGCCCCCGTCTTGATAATAATGGCTTTAACACGATATTAGAATCCGTGAGTGAATCTGTGACCAAACACTTCTTGAGAGAAAATATGGATAAGCTGTCTCCCGGCCCTGGCAGGATTTGTGATGGTATTGACTTACCGCCGACTGCAAACGTTACTATAAAAGAAGAACCAGTCGATGTTCATAGATGTCTTAAATGTAGTGTTACATTTAGCAACAAAAACGACCTATTAGAACATGAAAAAGAATTATGCGGAAGCATATTTAGAAAACATGAAAGTTTAGCAGCTCAAGTAGCAGAAACGGTAGCACTCAATAGATTAGAAGCAGAAATGCGAGTTTCAATACAAATTGGTGTAAGTGTAAGTGAAGATGAAGATTATATCAGAGAAGAGCGCGATGATAAAGTCTCTATTCATGATGCTGACAGAAAAATTAGAGTTCGCACTGCTTTAAGCGAAGAGCAACAGTTGATATTAAAAGAGCATTATGATATCAATCCTCGACCGAACCGAGATGAATTCAAAAAAATCGCCCAACAGATTGGTCTTGACAGTCGAGTAGTGCAGGTTTGGTTTCAAAACAACAGAGCTAGAGTGCGAAGGATGGCTCAAGTTATACCCGCGGCCGATCAGCCATTAGACTTGTCCACTAAGAAGTCGAACCCATCCGTGACGTCGAGTCCGTCTGTATCGCCAGCTTGCAGCATTTCTGTAACACATTCCGATTATGAAGAAGCTGTGAATCTCAGCCAAAGATCATCCCGCAGTACGACACCGCACCATACCAATTATTTGAATACGTATCCACATTCCAATTGTTCCTCCTCGTCCTTAAATGACGGTCGCTTATCCCCATCACCCGGTGACATGATAAACGGTCAAAAGCGTTTATTGCGACATAAAATGCCAATCAGCCCCATAATTCCAATGGACAAACTATTGAAATACAATGACCTAGTAAAATCGCGATCTCCATTGCTCAGCATGCATATGCCATCGGATGTCAACCAGCAGAGGTCGAGTCCCGGACCTCTGTACGAGCGGCCGCCGTGGGCCGATGATGTCCAAGGATCGAACGAATTCGACGACGACCCGACTGTACTTAAGAAGAGGAAATTGAACCAGAGCACCGAGTTCAAAGATGGCGAAGGGCAGTTCGTTTGCGACCAATGCGACAAAACGTTCGTGAAACAGAGCTCCCTCGCAAGACACAAATATGAACATTCAGGCCAACGGCCGTACAAGTGCGTGGAGTGCCCCAAGGCGTTCAAGCACAAGCACCATCTCACCGAGCACAAGCGGTTGCACACCGGCGAGAAGCCCTTCCAGTGCAGCAAGTGCCTCAAGAAGTTTTCACACTCCGGCTCCTACAGCCAACACATGAATCACAGGTTCGCCATCTGCAAGCCTTACAGAGATTAG
Protein Sequence: MKIHSQLPNITVINISTCEKLLTIEHCTAHILVRPVAGSGPGGEVKPEEEEDRGGSPLGPGGPYSCSQCRGAYPTREQLDRHEKLHSPNTQVDTVKYTCMKCHKSFANVYRLQRHMISHDESANLRKYKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRSPARKRNNALVASQLNNNMPSNGNTFPHFQPILNPKYNDAAAYLAAISSPESNFHHPPLVQPGMAPFYLPPSMPMGPASGMAPYSIPPSWRQLFEHIAAQQYQERKPDDYVSPNLNNSHTDPEDMIEEVTEEDDKRSEGSAELVMDIEDEAVSIKKEQDERENDPRSSPRHFDSVPLNNNSPRLDNNGFNTILESVSESVTKHFLRENMDKLSPGPGRICDGIDLPPTANVTIKEEPVDVHRCLKCSVTFSNKNDLLEHEKELCGSIFRKHESLAAQVAETVALNRLEAEMRVSIQIGVSVSEDEDYIREERDDKVSIHDADRKIRVRTALSEEQQLILKEHYDINPRPNRDEFKKIAQQIGLDSRVVQVWFQNNRARVRRMAQVIPAADQPLDLSTKKSNPSVTSSPSVSPACSISVTHSDYEEAVNLSQRSSRSTTPHHTNYLNTYPHSNCSSSSLNDGRLSPSPGDMINGQKRLLRHKMPISPIIPMDKLLKYNDLVKSRSPLLSMHMPSDVNQQRSSPGPLYERPPWADDVQGSNEFDDDPTVLKKRKLNQSTEFKDGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCVECPKAFKHKHHLTEHKRLHTGEKPFQCSKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01569194;
90% Identity: iTF_01569194;
80% Identity: iTF_01569194;