Basic Information

Gene Symbol
-
Assembly
GCA_027724725.1
Location
JALNTZ010000004.1:55211499-55213697[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 3.2 1.9e+02 4.0 3.5 1 23 21 43 21 43 0.96
2 19 0.027 1.6 10.5 6.0 1 23 141 164 141 164 0.93
3 19 0.092 5.5 8.8 2.7 1 23 173 195 173 195 0.98
4 19 0.0021 0.13 14.0 1.8 1 23 222 245 222 245 0.98
5 19 0.11 6.6 8.6 0.4 1 23 254 277 254 277 0.96
6 19 0.44 27 6.6 3.9 1 23 286 309 286 309 0.95
7 19 0.0053 0.32 12.7 1.6 3 23 320 341 319 341 0.96
8 19 0.0061 0.36 12.5 4.1 1 23 349 372 349 372 0.92
9 19 0.049 3 9.6 1.0 1 23 381 404 381 404 0.96
10 19 0.034 2.1 10.1 7.1 1 23 413 435 413 436 0.95
11 19 0.15 8.8 8.2 0.8 2 23 446 468 446 468 0.95
12 19 0.0014 0.082 14.5 2.5 1 23 477 500 477 500 0.98
13 19 0.0014 0.082 14.5 2.5 1 23 509 532 509 532 0.98
14 19 0.02 1.2 10.9 5.1 1 23 541 564 541 564 0.98
15 19 0.0016 0.094 14.4 1.0 1 23 573 596 573 596 0.96
16 19 0.00012 0.0074 17.8 2.9 1 23 605 628 605 628 0.98
17 19 7.9 4.8e+02 2.7 5.0 1 23 637 659 637 660 0.94
18 19 0.00047 0.028 16.0 1.9 1 23 669 692 669 692 0.96
19 19 0.08 4.8 9.0 2.8 1 23 701 723 701 724 0.96

Sequence Information

Coding Sequence
ATGTCGCTACTAAAATACTCGAAGAAGCTCGCCCACATGAAGCCTTCCCTGGACAATGTCCACCACTGTAAGGTTTGTCCGTATTTCACAACCTCACTTTTGCTCATGGTGAACCACGTTAAACGCCACCAAGCTCCCCCACAATATTTCAACTGTGAAAATATCGACGTCGAAACTTACCACTGCGAGGACTGCAATTTCCAGACAGAACTAACACTTCTTTTCAAGCAGCACGCCCGACTGTGTTATAGGAAGTCTGAAGAGAATTTACCAGAGCAAGTTTACTCAACTCAAAGTTTCATTTGCAAGAAGTGCAGTTTCGAAACACATTTCAAGCTTAAGTGGCTTCAGCACGGTACACAGTGTTTGGGGAGCAATCACCCTCAAATAGTAACAACTAATGATAAAATTACCACATGGTATCACTGCAACCAGTGTGAATGCAGATTCAAAAAGAAACCAAACCTGAAGGCACACAAAATTTTAAAGCATTTGAGTGACGATCAACGTAGGTGGTATTCTTGTGAACATTGCTCCTATAAATCCATTCTGAAATCGCGTTTAAAAGTACATGTAATGAGGCATATGAACAAACCAAAGAGACGGATTTCTTTAAAAACTCCCGGTGTTATGGAGTATGTGGATGAGCAGGGTATTAAATGGTATAAATGTGAAAAGTGTCCACATAAATCTAAAATTAAGTGGAATTTAATGAAACATATAAATTCGTGGCACTTACATGAGAAGGATATTACATGGCACGAGTGCCAGACTTGTCCATACAGAGGTAAAAATTTATTGGCTTTAAAGACACACATTATTGTAAATCATTTGAAAGATAAGGATGTCTCATGGCACAAATGCCAAGACTGTCAATTTAAGACTAAACATGATTCAGTATTAAAGGAACATATAAATGCGCAGCATTTAGATGAACAAGATATTATATGGAACATATGTGAAGAGTGTTCATATAAAACTAAATACCAAAGCAGCTTGTCACGTCACAAACGTCTATCACACAAAACTGAAAACGTAAAGTGGTACAAATGTGAAAAATGTCCATTCAAAACGAAACAAAAGAGCAATTTCAAGACGCACAGCAACTTTGTTCATATGAATAAAAAAGACATTAAATGGTACGAATGCCAAATTTGCTATTTTAAAACTAAATATGCGGGGTCTTTCAAAACTCACTTAATTATCCAACACGGGTGTGAAGAAAATATTAAATGGTTTAAATGTAACCAATGTCCACATAAAGCTAAAAAGAAGACGCATTTAAAAAAACATATAATTGCTCACCATTTAAATCCACAAGATATAGAATGGCGGCAATGTACAGAGTGTCTATATAAAGCCAAAGACTCGTCGAGGCTAAATAGTCACATTAAAGCACGCCACTTGGACGAGAAAAATATTAAGTGGTATAGATGTGATAAATGTGATTACAAAGCAAAAAATAACTTTACCTTGAAAAGTCATATCATGAGGCGACATACAAATTCACGCGATATTAAATGGTATAGATGTGATAAATGTGATTACAAAGCAAAAAATAACTTTACCTTGAAAAGTCATATCATGAGGCGACATACAAATTCACGCGATATTAAATGGTACGAATGTAAAGATTGCTCCTTCAAATTTAAATGTACCAGTAGTTTAAAGCTTCACATAAGGATGCGCCACTTGAAGGATGAAGATGTTAAATGGTATGAATGCTACAACTGTCCATATAAAGCTAAAACAAAAACCAATTTGAGAACTCATATAAATGCTCGGCATTTGGACAAAGAAGCCATTGAATGGTATAAATGTGATAAATGCGATTATAAATCAAAACGAACCAGTGACTTGAAAACTCATATCATGAGGCGACATACAAATCCACGCGATATTAAATGGCACGAATGTAAACTTTGTCCCTTCAAAGCCAAATGTCGCGGTAATTTAAACCAGCACGTAAACATACACCATTTAAAGGATGAAGATGTTAAATGGTACGAATGCTACAAATGTCCATACAAATCTAAAAATAAAAGCACATTGAAAAATCATATAAATGCTCGGCATTTGGACAAAGAAGCCATTGAATGTTATAAATGTGAAAAGTGTCCATACAAAAATAAACTCAAGTCACAGTTAAAAATTCATGTAGCTAGGCATCATTTGGACAGACAAGGGCGTAAATCGTAG
Protein Sequence
MSLLKYSKKLAHMKPSLDNVHHCKVCPYFTTSLLLMVNHVKRHQAPPQYFNCENIDVETYHCEDCNFQTELTLLFKQHARLCYRKSEENLPEQVYSTQSFICKKCSFETHFKLKWLQHGTQCLGSNHPQIVTTNDKITTWYHCNQCECRFKKKPNLKAHKILKHLSDDQRRWYSCEHCSYKSILKSRLKVHVMRHMNKPKRRISLKTPGVMEYVDEQGIKWYKCEKCPHKSKIKWNLMKHINSWHLHEKDITWHECQTCPYRGKNLLALKTHIIVNHLKDKDVSWHKCQDCQFKTKHDSVLKEHINAQHLDEQDIIWNICEECSYKTKYQSSLSRHKRLSHKTENVKWYKCEKCPFKTKQKSNFKTHSNFVHMNKKDIKWYECQICYFKTKYAGSFKTHLIIQHGCEENIKWFKCNQCPHKAKKKTHLKKHIIAHHLNPQDIEWRQCTECLYKAKDSSRLNSHIKARHLDEKNIKWYRCDKCDYKAKNNFTLKSHIMRRHTNSRDIKWYRCDKCDYKAKNNFTLKSHIMRRHTNSRDIKWYECKDCSFKFKCTSSLKLHIRMRHLKDEDVKWYECYNCPYKAKTKTNLRTHINARHLDKEAIEWYKCDKCDYKSKRTSDLKTHIMRRHTNPRDIKWHECKLCPFKAKCRGNLNQHVNIHHLKDEDVKWYECYKCPYKSKNKSTLKNHINARHLDKEAIECYKCEKCPYKNKLKSQLKIHVARHHLDRQGRKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01568339;
90% Identity
-
80% Identity
-