Basic Information

Gene Symbol
-
Assembly
GCA_000696155.1
Location
NW:899395-909047[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 5.7e-08 2.1e-06 27.3 0.2 1 23 499 521 499 521 0.97
2 10 9.2e-06 0.00033 20.3 1.0 1 23 527 549 527 549 0.97
3 10 9.4e-06 0.00034 20.3 1.6 1 23 553 575 553 575 0.98
4 10 3.5e-06 0.00012 21.7 0.3 1 23 581 603 581 603 0.94
5 10 1.6e-05 0.00059 19.6 2.6 1 23 609 631 609 631 0.98
6 10 4.2e-06 0.00015 21.4 0.6 1 23 637 659 637 659 0.98
7 10 1.9e-07 6.9e-06 25.6 0.8 1 23 664 686 664 686 0.98
8 10 3.1e-06 0.00011 21.8 0.6 1 23 692 714 692 714 0.97
9 10 0.00041 0.015 15.1 5.3 1 23 720 742 720 742 0.98
10 10 0.0023 0.084 12.8 1.5 3 20 750 767 748 770 0.92

Sequence Information

Coding Sequence
ATGTGGTGTGATAACACTATAACTTTTGCACCAAATATCTGTCGTCTGTGTGCTAGTGTTAGTGAGGTTGTCATTCCAATGTTTGGAAAAGAAGGCGATAAAGAAAgaattgatttaaaaattaagaaatgtttaccAATTGTTGTAAGAGAAGAAGACTGCAAGCCAAAGCAGGTGTGTTTCACATGTGTGTCCAAGCTTGAGGTGTGCATGGATCTGGTTGAACAATGTCTTGCTGCAGAGTTCAAGTTTGAGTCAGTATTGCAAGCTAGATTTCCAGTTCTTAAAGGAACTGGAGCTGAAGCTACAGCTCTGCAGaatgatGTGGATCCTCAGAAGAATGGGATAGTACATGACACAGGTTTGGGTGTTGTGCCATTATTGGCTTCCCGGCCAACCCGTGTGTGGCCTGAAGATATTGGGAAAACTGATCAGAATGCAGGGAATACATTGACTGTCCAGCATGATGGAAGTGTAATTGTACTGAGCAAAGTTGATGCCGAAGCTGTTGGGCAGCATTCTAGAGAAGATTGTCAGGATATCTTGCTTATGGTAGAGTTGAAATATAAAGATGTGCCAGAATCACAGCAATCAACTGTAGCAAAGGCTCCAGCAATTACATATTCAGTGGAACCACATGAAAGTATTGTATCCAAATCACAAAGTCAGTCATTCTCAACAGAAGCAAATAAAGTTCACACAGTTACATTTACAAATGAGGTACCAACAGTTTCAACATCCAAAGCTCATACTCTGTCATACACGATAGAGCCTCAGTCTGTTTCTTCTAGCAAAACATATACACTAACTTACGCAACAGAGACACAGCCTGTAACTGCTGCAAAAACCCAAACAATTACTTACACAACTGAAACACAGCCTATTAATGTGTCAAAAATCCAGACGTTTTCGTACACAACAGATGctataaataaaccacagacaaTGACTTACACAGCAGAACCACATTCAGATTCATCTGAAAAGGCACATGCACTTGTGTATACAGCTGATCAACATCCGGTTTCTCTTAGCAAGACTCACAGTATGGACTTTACAGGAGAATTACAGCCTGTAGCACTAACGAAGAGTCATATGCTGTCATATGCATCTGATGAATCTCCTACTTTGACTAGTAAAACCCTCCTTGCTTATACAGCAGAACATACCACAAGTAGTGGTACAAAATCACACCTCCTGACGTACACATCGGAACAGGTATCAGATGCAAGCAACAAGACTCCCACTTTGGCTTATACAGAAGAACTGCAGCCCAACACTTTAGCAACAAAGGCAGATGTACTTTGTGCTACAGCAGAGGTTCAGCCAGATACAAGCACTAAAAATGCAACccttgtcttcccatctgagtCAGAAGAAGTTCTAGGGCTGGAATCTGCCATTCCTCAACAGACGACCATACTCATTGACACTAATAAATACAAAGCAGCAGTTGGAGGTGAGAGCATTAATCCTCCCCGCCCAGAGAAACCATTCCCATGCACCGAGTGTGGCAAATCATTCATGCGCCGCAGTAACTTGAATGCTCACATGGGGGTGCACACTCAGGTACGTCCTCATAGCTGTGAACAATGTGGCAAAAGTTTTGTGCTTCGTTGGGACTTGACACTACACCAACGCATTCATGCAGGACTCTTCTCATGTGAGTTTTGTAGCAAGGCTTTTAGCGTGCGTGGGAAACTTGAAAGACATAGACGAACACACACTGGTGAACGCCCATATCCATGCATCACATGTGGTAAAGCTTTCGGGGATAAACGGAATCTTGAGTCACATATGCGTACACATTCGGGTGAACGTCCGTTCATGTGTGGTACTTGTGGACGGAGGTTCCGTGTACGATCACATCTTTCAGACCACCGACGGGTTCATTCACAGGAGGCTCCTTTTACGTGTGATGTGTGTGGAAAGTCATTCAAATGGAAGACAAACCTAAACATTCACCTAAAGGTACATGCTGGTGAACGTTTTACATGTAGTGAATGTGGGCGTGAATTTTCTCGTCGAGCTGATCTTGCTAAACATAGGCGTTCTCACTCAGGTGATCGTCCCCATGTTTGTGGAATTTGTGGAAAGAGTTATGGTGACAAAGCCATGCTCCAGAAACACCTCAAATCACACAGTGAGCACAAACCATTTACATGTGATATATGTGGAAAAAGCTTCCACTTCCATTGGTATCTGGCAACACACAAAAAGACTCATGCAGAGGAAGGTACTTTTGGTTGTGTTGAGTGTGGCAAAGTTTTTAACAAACGAGGTAACCTATTGAGCCATGCAAAATGTCATGTTGATTCTTCTACACATTCCAAAAGTCACTCTGTTGACGTGAAATTGGTGCTGCCTGAGGAAGCTCCAGCTCTTGAGGCTACGCTCTGA
Protein Sequence
MWCDNTITFAPNICRLCASVSEVVIPMFGKEGDKERIDLKIKKCLPIVVREEDCKPKQVCFTCVSKLEVCMDLVEQCLAAEFKFESVLQARFPVLKGTGAEATALQNDVDPQKNGIVHDTGLGVVPLLASRPTRVWPEDIGKTDQNAGNTLTVQHDGSVIVLSKVDAEAVGQHSREDCQDILLMVELKYKDVPESQQSTVAKAPAITYSVEPHESIVSKSQSQSFSTEANKVHTVTFTNEVPTVSTSKAHTLSYTIEPQSVSSSKTYTLTYATETQPVTAAKTQTITYTTETQPINVSKIQTFSYTTDAINKPQTMTYTAEPHSDSSEKAHALVYTADQHPVSLSKTHSMDFTGELQPVALTKSHMLSYASDESPTLTSKTLLAYTAEHTTSSGTKSHLLTYTSEQVSDASNKTPTLAYTEELQPNTLATKADVLCATAEVQPDTSTKNATLVFPSESEEVLGLESAIPQQTTILIDTNKYKAAVGGESINPPRPEKPFPCTECGKSFMRRSNLNAHMGVHTQVRPHSCEQCGKSFVLRWDLTLHQRIHAGLFSCEFCSKAFSVRGKLERHRRTHTGERPYPCITCGKAFGDKRNLESHMRTHSGERPFMCGTCGRRFRVRSHLSDHRRVHSQEAPFTCDVCGKSFKWKTNLNIHLKVHAGERFTCSECGREFSRRADLAKHRRSHSGDRPHVCGICGKSYGDKAMLQKHLKSHSEHKPFTCDICGKSFHFHWYLATHKKTHAEEGTFGCVECGKVFNKRGNLLSHAKCHVDSSTHSKSHSVDVKLVLPEEAPALEATL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00396549;
90% Identity
-
80% Identity
-