Basic Information

Gene Symbol
-
Assembly
GCA_037414775.1
Location
JAZBGX010000375.1:19002-20415[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0049 0.28 11.4 1.3 2 21 138 157 137 158 0.92
2 10 0.0085 0.49 10.7 3.3 1 23 168 190 168 190 0.98
3 10 0.0072 0.42 10.9 1.8 1 19 233 251 233 253 0.96
4 10 0.053 3.1 8.2 0.2 2 23 257 277 256 277 0.95
5 10 0.00085 0.049 13.8 0.1 3 23 284 305 282 305 0.95
6 10 0.00014 0.0081 16.3 2.5 1 23 310 332 310 332 0.99
7 10 2.1e-06 0.00012 22.1 3.8 1 23 338 361 338 361 0.96
8 10 0.00021 0.012 15.7 3.8 1 23 367 389 367 389 0.96
9 10 9.6e-07 5.6e-05 23.1 0.8 1 23 395 418 395 418 0.98
10 10 2.5e-05 0.0015 18.6 1.0 2 23 427 448 426 448 0.96

Sequence Information

Coding Sequence
ATGGACATggacaaaaaaatttgtagattatgTTCAGGGAAATTTCccgtttatttttctttattaaattcaaatattccaaatatgTTGGAAGCTTTAACATCAATTAagGTATCCGCAAACGATGAACTATCCACTGTTGGTTGTACgaaatgtttattaaatttgaaattagcaTTCAATATTCAACAGAATATACTAAAATCCGATGAAAAATTGCGTAATAATTGTAtgaattttgttggaattaaaGAAGAAATTTATGATGTGACttttaatgagaaaattgaacCGATTTCTGCAAAAATAACAGAAACATTGGAAATTTGTGATGGTTTATGTAGAATTTgtggaatttcaattgaagaCAATATGATCAATCATCTAAAAGAACATTTCCAATCAGAACAAGTGTGCAATAATTGCCAAGAAACCTTCAAAAATATACATGAATATCGTcaacatacaacaacaaactgtaGACAATTGAAAGTAGAATTTTACACGTGTGAATCTTGTGATAGTAAATTTCGTTACAAATCGTTCTATAATTTACATGTAAAGAATCATCGGCTCAATGATAATACTGTTGGTAATGTTGTAGATCGTGATGATGTCAATGAAGGTAATGAATCAATAGATGGGAAACATTTGAGTGGTAAATACTTTCGTATTGCAGTCGATAATAAGAAGACGTTTCGTTGTGATGTTTGTTTGAAAGTTTATAAATCACGCCGACAATTCACTGTTCATTCGCACGAACGTAAAGAATGTCCAATATGTAAAGCAAACATCACTAGAAGCAATTGGATAAAACATGTCCGTAATCACAATTCAGGACCGCAAATATGTGAATTATGTGGGGCAACATTACGAAGTTTCGAAAGCTTAAGGGCCCATATGAATTATGTACATAGTCAAGAACGTTATAAATGTGACGAATGTAATTTAGTTTTTAAATTACGTTATACTTATATGCTGCATCGTAAAACgcataataatgaaaaagatCATATTTGTGATCAGTGCGGTCGCGGTTTTATAACGAAACATTATCTAAATAAACATATGCGTAttaaacatttgaaattacGCCCGCATATATGTGAATTTTGTAATAGAAGATTCTCAACTAGAAATGCATGGAGGACACATCAGCGACAACATACAAATGAAACACCGTATCGTTGTGAAGTGTGCGGTGAAGCTTTCCGACAAAACGTTTCATTACGTACACATCGGAAATCTAaacataatattattgaaccGATAACGTGTGCATGTGATGTTTGTGGTAAAGAATTTAGCAGTCGACAAGCTGTTTTCAGTCACATGAGATTACATTGA
Protein Sequence
MDMDKKICRLCSGKFPVYFSLLNSNIPNMLEALTSIKVSANDELSTVGCTKCLLNLKLAFNIQQNILKSDEKLRNNCMNFVGIKEEIYDVTFNEKIEPISAKITETLEICDGLCRICGISIEDNMINHLKEHFQSEQVCNNCQETFKNIHEYRQHTTTNCRQLKVEFYTCESCDSKFRYKSFYNLHVKNHRLNDNTVGNVVDRDDVNEGNESIDGKHLSGKYFRIAVDNKKTFRCDVCLKVYKSRRQFTVHSHERKECPICKANITRSNWIKHVRNHNSGPQICELCGATLRSFESLRAHMNYVHSQERYKCDECNLVFKLRYTYMLHRKTHNNEKDHICDQCGRGFITKHYLNKHMRIKHLKLRPHICEFCNRRFSTRNAWRTHQRQHTNETPYRCEVCGEAFRQNVSLRTHRKSKHNIIEPITCACDVCGKEFSSRQAVFSHMRLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-