Basic Information

Gene Symbol
ZNF236
Assembly
GCA_037414775.1
Location
JAZBGX010000494.1:10380-14931[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.00024 0.014 15.6 2.4 1 23 118 140 118 140 0.97
2 23 0.00023 0.013 15.6 0.2 1 23 146 168 146 168 0.98
3 23 0.00016 0.009 16.2 0.3 2 23 174 195 174 195 0.97
4 23 9.8e-05 0.0057 16.8 0.4 1 23 201 223 201 223 0.98
5 23 0.11 6.6 7.1 0.6 2 23 234 255 233 255 0.93
6 23 4.4e-06 0.00025 21.0 1.6 1 23 279 301 279 301 0.96
7 23 0.00021 0.012 15.7 0.5 1 23 307 329 307 329 0.97
8 23 0.0014 0.083 13.1 1.5 1 23 335 358 335 358 0.96
9 23 0.0034 0.2 11.9 3.5 1 23 368 391 368 391 0.97
10 23 4.1e-07 2.4e-05 24.3 0.9 1 23 459 481 459 481 0.98
11 23 8.6e-06 0.0005 20.1 1.5 1 23 487 509 487 509 0.98
12 23 0.0005 0.029 14.6 0.1 1 23 515 537 515 537 0.98
13 23 5.1 2.9e+02 1.9 1.1 1 23 545 567 545 567 0.95
14 23 0.001 0.057 13.6 2.3 1 23 622 644 622 644 0.99
15 23 0.0052 0.3 11.3 3.1 1 23 650 672 650 672 0.97
16 23 2.3e-05 0.0013 18.7 3.0 1 23 679 701 679 701 0.98
17 23 2.2e-05 0.0013 18.8 3.8 1 23 752 774 752 774 0.97
18 23 1.5e-07 8.5e-06 25.7 1.1 2 23 786 807 786 807 0.97
19 23 6.3e-06 0.00037 20.5 2.5 1 23 813 835 813 835 0.96
20 23 6.9e-06 0.0004 20.4 0.9 2 23 844 865 843 865 0.96
21 23 0.15 8.4 6.8 4.2 1 23 871 894 871 895 0.92
22 23 5.5 3.2e+02 1.8 0.0 9 23 1026 1040 1024 1040 0.89
23 23 4.9e-05 0.0028 17.7 1.9 1 23 1046 1069 1046 1069 0.98

Sequence Information

Coding Sequence
atggCTCAAGatagttttttaattaatgaaaaattaccaacattaATAGCTTTACCAATCGAAACTTATGATAATATAATccaattatcgaataatttacgTGTTGTTTCCGATGTTGTTATTAAACCATTATCTGAAGGTTCGTTTTATATTGTCGATCAGAATGAGgtGAATATCAACGGAAATCCAGTAGAActtctaaacaacaacaacaataataatacgttAATGTTACTGAATATACCAACAGATCAGCAAATTAATGCAAAGAATGAAGAAACtgataaATTATCTACAAGTCTCGATGTCATagtagaaaaaacaaatgataatacaaAACCAATATCAGTATATCGCTGTACAAAATGTAATGAAGAATTCAAAAAGTTTAGTTTATATCGTAAACATATTATATGGCATagtaatataaagaaatacaAATGTGATAAATGTTCAATCAGTTACAATATTGAagagaatttgaaaatacataTGGCAATGCATAATGATGGTAAACCGACATGTCCAATATGTAAAATATCATTTCAACGATTAGCTAGTTTAAAATCACATTTAATGTTACATCAAATCGAAGAATTATATACATGCGATGAATGTTCATTGGAATTTCAACGTGAAgaagaattaaataaacatttacaaAGTCACATGAATCACACGAAAAATGATGATGGTTTGATTTGTTCGTATTGTCGTGTTACATTTAATGAACCAAATCTTTATAAAGAACATGTAGCACATCATATCAAAgtgaaaaaaatgattgtttctGGAAAGCGTACACGTAAAACTCATAATAATCGCGAATATCATCATATTTGTAATGTTTGTCAAAAGTCTTTTTCGAAAGCATCATTATTGGAGCGCCATTCACGTGTTCATAGCGGCGAGAAGccatttattTGTCAATTCTGTGAACGTGGCTTTAATCAAAAAGGCGCTTTACAAGTTCATTTAACTAAACATACAGGTATAAAACCATATCATTGTACATTATGTTCAGCTGAATTCTATCAAAAAGGTAATTTACGTGTACATGTTGAAAAAACACATACGGCTCCATCACCTGGTGTTAAAACCTACAAATGTTCACATTGTTcttgtatatttaaaaaaattgcaagTTTGAATGTTCATATAACAAGGGCACATGCTAGCAATCAAAATCGTCCAGATGAAATGGtcgatttaatcaataaattgaaacaaattgaaCCGAATAGTCAACAAATACCAAATTCAAGagacgatgataataataatgtgaattATATACGTGTAGCTGAATCATTTGCAGACGGTACAACACGTCGTTATTTGATTAAACAGAAAAGAATCAACGATActagaatttatatttgtaattattgttccAAGGAATTTAAAAAACCATCAGATTTAATCCGACATACACGTGTCCATACACGCGAACGTCCATTCATgTGTAAAGACTGCAATATATctttttcattgaaatcaacgttattatCGCATTTGAAAACACATACAGGAAAATGTCATTATATGTGTCCGATTTGTATGAAGAAATTCTCAACAGCGCGTGCTGTAAATATTCACTTGagAGGCCATTCCGAACGTTTAACGCAAGCTTTCAAATGTAATCCATGTAATAAATGGTTTAGTTCAGTGCAAAAAATGTTAGTCCATAAAGAGAAACATCGTAGACAAGAAGAGAATTCATTAATAGAACAACAAGTTGAAATCGATGAGAATTTAAATAGAGAAATATCAACAGATCTTGCAAtacaattaccaaataatattCAACCAACTTGTGAtccattatttatagaaacaacaacaaacaataataataaacaatacgAATGTCATATatgcaaattgaaaatttcaaaattgtacaatttacGAGAACATCTCAGTACGCATTCAGCCGATAAACATTATAAATGTGAACATTGTCCaaaaTTGTTTTTCACATTGGATGCTTTCAAAGAACATAAATTCGTACATGATACCTCTCCAAAATTATATCATTGCAGTGATTGTGgtaaaaaattttcaacaattccaTTATTGAAACGCCATAAATTGAGacataatcaacaatatttatgttCATATTGTGATAAAgaagaagatttggatattaataatataaataataatgataaagaagTTGAATCAGatgtaacaaaaattaataatgacagtaataataatactaataataatagtaataaacgTAAATATGTTTGTACATATTGTAAACGTACTTTCACAAGTAAATCGACATTTTCCAAACATTTGGATAATCATATGAAACGTAAAAAAAGTGAACCAGTATTGCGTGtatgtaattattgtaataaaggATTTAAGAAACAATCCGATTTAGTACGTCATATACGTACGCATACCGGTGAACGTCCATTTCTATGTGATAAATGCGATAAACGTTTCTCATtgaaatcaacattattatcacaTCAACGTACACATAATCCAGTtaatacgaaaaaaataacatgTAATATATGTAATTCAACATTTACATCGAAATCAAGTTTAAGAGTACATATGAGTTTACATACAGGTATTAAACCGTACGATTGTGTATATTGTCCAATGAAATTTCGTACATTGTCACATAAAAAATATCACGAAGCATCACAACATCATTGTTGtacgaataataatgaacatcatttattgaaaatgaaaaatgataataatttattagatggtgatggtgatgatttattaaatgacAATCAACAAAATGATATTACTTTAGAAATTGCAACGACTAATCAATTCGATgagaaaaatgataatattctAGTTGTACAAGAATCATTACAATTACCATCattgattaatgataataataatctaaatataaaCGAAACAATACAATTAGAACCgaatattttacaacaatgGCAGAATAATTTACTACTACAAGATCCAATattacaatcatcatcattgataCAATTGGATGATGGtacattattgaatataaaaacaatcaataatgatattgattttgttgataatcatAATTTAGGTTTTGATACTGAAGAGGCATTAGAGAAACATACTAAATTGCATTCAGGCTATCGTCCATTCACTTGTATGTAttgtaataatagtttttcgAAACAACAAAGTCTATCAGCACATATGAAAAGGATACATAAATTGTCCAATAGTTTATGGAAAGATGATGTATTCTTCACATTATCgtcttga
Protein Sequence
MAQDSFLINEKLPTLIALPIETYDNIIQLSNNLRVVSDVVIKPLSEGSFYIVDQNEVNINGNPVELLNNNNNNNTLMLLNIPTDQQINAKNEETDKLSTSLDVIVEKTNDNTKPISVYRCTKCNEEFKKFSLYRKHIIWHSNIKKYKCDKCSISYNIEENLKIHMAMHNDGKPTCPICKISFQRLASLKSHLMLHQIEELYTCDECSLEFQREEELNKHLQSHMNHTKNDDGLICSYCRVTFNEPNLYKEHVAHHIKVKKMIVSGKRTRKTHNNREYHHICNVCQKSFSKASLLERHSRVHSGEKPFICQFCERGFNQKGALQVHLTKHTGIKPYHCTLCSAEFYQKGNLRVHVEKTHTAPSPGVKTYKCSHCSCIFKKIASLNVHITRAHASNQNRPDEMVDLINKLKQIEPNSQQIPNSRDDDNNNVNYIRVAESFADGTTRRYLIKQKRINDTRIYICNYCSKEFKKPSDLIRHTRVHTRERPFMCKDCNISFSLKSTLLSHLKTHTGKCHYMCPICMKKFSTARAVNIHLRGHSERLTQAFKCNPCNKWFSSVQKMLVHKEKHRRQEENSLIEQQVEIDENLNREISTDLAIQLPNNIQPTCDPLFIETTTNNNNKQYECHICKLKISKLYNLREHLSTHSADKHYKCEHCPKLFFTLDAFKEHKFVHDTSPKLYHCSDCGKKFSTIPLLKRHKLRHNQQYLCSYCDKEEDLDINNINNNDKEVESDVTKINNDSNNNTNNNSNKRKYVCTYCKRTFTSKSTFSKHLDNHMKRKKSEPVLRVCNYCNKGFKKQSDLVRHIRTHTGERPFLCDKCDKRFSLKSTLLSHQRTHNPVNTKKITCNICNSTFTSKSSLRVHMSLHTGIKPYDCVYCPMKFRTLSHKKYHEASQHHCCTNNNEHHLLKMKNDNNLLDGDGDDLLNDNQQNDITLEIATTNQFDEKNDNILVVQESLQLPSLINDNNNLNINETIQLEPNILQQWQNNLLLQDPILQSSSLIQLDDGTLLNIKTINNDIDFVDNHNLGFDTEEALEKHTKLHSGYRPFTCMYCNNSFSKQQSLSAHMKRIHKLSNSLWKDDVFFTLSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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