Basic Information

Gene Symbol
-
Assembly
GCA_037414775.1
Location
JAZBGX010004947.1:877-5950[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 31 0.00073 0.042 14.0 0.1 1 23 9 31 9 31 0.98
2 31 7.9e-06 0.00046 20.2 0.9 1 23 37 59 37 59 0.98
3 31 4.1e-07 2.4e-05 24.3 0.1 1 23 65 87 65 87 0.98
4 31 0.4 23 5.4 5.3 1 23 93 116 93 116 0.96
5 31 0.18 10 6.5 0.3 2 23 125 147 124 147 0.93
6 31 0.00015 0.0086 16.2 2.1 1 23 153 176 153 176 0.96
7 31 0.0016 0.095 12.9 1.9 2 23 178 199 177 199 0.98
8 31 0.00032 0.018 15.2 0.4 3 23 234 254 233 254 0.97
9 31 0.0046 0.26 11.5 3.7 1 23 264 287 264 287 0.97
10 31 0.45 26 5.3 0.5 1 23 294 316 294 316 0.94
11 31 3.3e-07 1.9e-05 24.6 2.0 1 23 322 344 322 344 0.98
12 31 1.7e-06 9.5e-05 22.4 1.2 1 23 350 372 350 372 0.97
13 31 0.00034 0.02 15.1 2.0 1 23 385 408 385 408 0.96
14 31 8.1e-06 0.00047 20.2 3.6 1 23 414 436 414 436 0.98
15 31 0.00053 0.03 14.5 5.7 1 23 442 464 442 464 0.98
16 31 0.00024 0.014 15.6 1.2 1 23 470 493 470 493 0.93
17 31 1.9e-05 0.0011 19.0 1.6 1 23 497 519 497 519 0.96
18 31 6.3e-06 0.00036 20.5 3.3 1 23 529 552 529 552 0.98
19 31 0.0017 0.098 12.9 0.3 1 23 559 581 559 581 0.98
20 31 1.7e-05 0.00097 19.2 5.2 1 23 587 609 587 609 0.97
21 31 9.8e-07 5.7e-05 23.1 2.2 1 23 615 637 615 637 0.99
22 31 7.9e-05 0.0046 17.1 2.6 2 23 652 674 651 674 0.95
23 31 8.9e-06 0.00052 20.1 2.5 1 23 679 701 679 701 0.98
24 31 0.0012 0.069 13.4 0.2 1 23 707 729 707 729 0.98
25 31 6.2e-05 0.0036 17.4 0.9 1 23 735 758 735 758 0.94
26 31 0.00022 0.013 15.7 1.3 1 23 762 784 762 784 0.98
27 31 0.003 0.17 12.1 7.0 1 23 794 817 794 817 0.97
28 31 0.0059 0.34 11.2 0.5 1 23 824 846 824 846 0.96
29 31 1.9e-05 0.0011 19.0 5.2 1 23 852 874 852 874 0.98
30 31 5.2e-07 3e-05 23.9 3.4 1 23 880 902 880 902 0.98
31 31 0.46 27 5.2 6.7 1 23 908 931 908 931 0.96

Sequence Information

Coding Sequence
ATGCACAATGCTAATccacaaaaatatatatgcgATTTGTGCGGTAAAGAAATAACAACATTGAAAGGTCTACGTGACCATCGTAATATCCATTTGGATGTGAAATCATTTGAATGTGTTACGTGTGGTAAGAAATTCGTTCGACGATTGACTTTAGTCAATCATCTACGTACACATACCGGAGAGAAACCGTATATTTGTAATGTTTGTGGGAGGGCTTTTGCACAACAAAGTCCTCTAACAATACATTTGCGCACGCACACCGGAGAAAAACCGTACAATTGCGAAATTTGTCAAGAGAAATTCGTTAGTAAGCATGCTTGTGATTATCATATGAAgaaaaaacatcaaaaattgaGCAACGAGTCGAATCAATGTGCTCTATGTTTGCGAGTCTTTCAATCGCTGCAAGGCTTGAAACAACATTGGTTATATAATCATCCGAAATATCGTCCATATACATGCGAGATATGTAAGCATTCATTCAAGAAAGTATCTCTATTGAAGATTCATCAATCGAATGGTCATAAACAATGTCCAGTTTGTTTGAAATATCTACAAACtaataaaacattgaaaaatcatATGAAAACCCATACGCaagattataaaatattttgtgaaatttgttGTCGAGGCTTTTTGAATAATAGTGCATGTCGAGCACATATAGAAAGTAAACATAATCGTACACAATTTTGTGAGACTTGCGGTAAATCGTTGTCGAATCAATACGCTCTAGATGCACATCGGAAATTACACGAGcgaaattataaagaaaatcgtAATTTTGAATGTagattttgtacaaaaaaattcttacaatCAACCCATTTGCAACAACACATCAATGTAATGCACAATGATAATCGCCGTAAATTCATTTGTGATTTTTGTGGTAAACAACTATTATCGACTACTGGTTTAAAAATCCATACAAAACTACATACGGGTAGCAAAGAGTATGATTGTAAAGTTTGcaataagaaattttccagGCAAACTTTATTAACAATCCATTTACGGACACATACCGGTGAGAAACCGTACGATTGTAGTTATTGCGATAAGAAATTTGCACAACgtaataatttgattctacATTTACGCCAACATACCGGAGATAAACCGTACCAATCAAGTGATGGTGGTTATCAATGTAATCAATGCCAAAAATATCTCAAGACTTTACCATCGTTGAAACGACATTTAAGATTTGTCCATACCGACAATCGTCCTTACACATGCGACATTTGTAAGAAATCATTTAAACTTAAAGACCATTTGGCGACACATCGGAATTCACacgagaaaatattgaaatatcaatGTGATATTTGCGAGAAGAAATTCTATATGAATCatcatttgaaaattcataagGAACGACATACGaacattagaaaatattgttgtgAAATTTGCGGTCAAcgatttattttgaatggtGATTATAAACGGCATATGGATGGTAAACATATGAATGTGTTTCGTTGTGATGAATGTGGGAAATCGTTGTCTGATAAGcattcattgaaattacatAGAGCACTACATGACGACAATTATACGGAGAATCGTCATTACAAATGTGAATTGTGTACGAAATCATTTCGGCAATTATTGCATTTGAAAGTCCACATTCGACGGATGCATAACGACAATCGACATAACTATATATGTGACTTATGCGGTAAAGAGATAACAACGTTGCAACGTTTGAACGAACATAGAAATACACATTTCGATTTGAAATTGTTCGATTGTAGTAATTGCGGTAAGAAATTCACGAAAAAGTGCTCACTCACTTTACATTTACGTACACATACCGGAGAAAAACCGTATAGTTGTCATATTTGCGGTAAATCATATTCGCAACGTACTCCTCTAACCGTACATTTACGTAAACATACCGGAGAGAAACCgtATCATTCAACATCCGATGGTTCACTTCAATGTCCGCATTGTTCGAAAACATTCAAAAAACGAGCCTTTTTCATACGCCATCTATTATCTGTACATAGCGCAACATCCTATTCATGTGATATATGTAAGAAAACATTCCAACAAAAGAATGCATTGAAGGTGCATCGTAAACGACATTATCGTACTGAACGTTTCAAATGTGACATATGCCAAATGATAGTTGATAGTAATTATGCATTGAAGATACATCAAGATCGCCATTTGAAGAATTACCATTTCTATTGTGAGATTTGTGGTAAAGGATTTGTTAAGAATAGCGGCTATAAGAATCATAAAAATGCTAAACATAATCATACGTTCAGTTGTGATGTTTGCGGTAGATCATTGAATAGTGAACGTAGTTTGAGATCGCATAAGAAACGACatgaagaaaattatatgGAGAATCGTAATCATAAATGTGAATTTTGTCGTAAGACATTCATGCAAGAATTCCATCTGAAATTGCACATCAAACGCATGCATAATGACAATCGTCCGAAATACATCTGTGATTTGTGTGGCAAAGAATTGCGGAGTTTGGAGAGTTTCAAAGACCACAACAACTACCATTTGGGTAATAAAATGCATGAATGCGGCACGTGTGGCAAGAAGTTTATACGTAAATGTACTTTGAGAATACATTTACGTACACATACCGGTGTTAAACCGCATACGTGTCATATTTGTGGTAAAGCGTTCACACAACGTAGTCCTTTAACTATACATTTACGTAAACATACCGGAGAGAAACCGTACAGTTGCGATATTTGCCATGAGAAATTCTTTAGTAAACACGAACGAGATTATCATTTGAAGAAGAAACATCAAGCTTTACAATGA
Protein Sequence
MHNANPQKYICDLCGKEITTLKGLRDHRNIHLDVKSFECVTCGKKFVRRLTLVNHLRTHTGEKPYICNVCGRAFAQQSPLTIHLRTHTGEKPYNCEICQEKFVSKHACDYHMKKKHQKLSNESNQCALCLRVFQSLQGLKQHWLYNHPKYRPYTCEICKHSFKKVSLLKIHQSNGHKQCPVCLKYLQTNKTLKNHMKTHTQDYKIFCEICCRGFLNNSACRAHIESKHNRTQFCETCGKSLSNQYALDAHRKLHERNYKENRNFECRFCTKKFLQSTHLQQHINVMHNDNRRKFICDFCGKQLLSTTGLKIHTKLHTGSKEYDCKVCNKKFSRQTLLTIHLRTHTGEKPYDCSYCDKKFAQRNNLILHLRQHTGDKPYQSSDGGYQCNQCQKYLKTLPSLKRHLRFVHTDNRPYTCDICKKSFKLKDHLATHRNSHEKILKYQCDICEKKFYMNHHLKIHKERHTNIRKYCCEICGQRFILNGDYKRHMDGKHMNVFRCDECGKSLSDKHSLKLHRALHDDNYTENRHYKCELCTKSFRQLLHLKVHIRRMHNDNRHNYICDLCGKEITTLQRLNEHRNTHFDLKLFDCSNCGKKFTKKCSLTLHLRTHTGEKPYSCHICGKSYSQRTPLTVHLRKHTGEKPYHSTSDGSLQCPHCSKTFKKRAFFIRHLLSVHSATSYSCDICKKTFQQKNALKVHRKRHYRTERFKCDICQMIVDSNYALKIHQDRHLKNYHFYCEICGKGFVKNSGYKNHKNAKHNHTFSCDVCGRSLNSERSLRSHKKRHEENYMENRNHKCEFCRKTFMQEFHLKLHIKRMHNDNRPKYICDLCGKELRSLESFKDHNNYHLGNKMHECGTCGKKFIRKCTLRIHLRTHTGVKPHTCHICGKAFTQRSPLTIHLRKHTGEKPYSCDICHEKFFSKHERDYHLKKKHQALQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-