Basic Information

Insect: Zeugodacus cucurbitae
Gene Symbol: wek_1
Assembly: GCA_028554725.2
Location: CM053020.1:71396768-71399192[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.7e-05 0.0022 19.4 1.8 1 23 370 393 370 393 0.96

2 8 1.3e-05 0.0018 19.7 0.6 1 23 402 424 402 424 0.99

3 8 0.0075 0.99 11.0 0.1 2 23 434 456 433 456 0.92

4 8 0.00044 0.058 14.9 0.0 1 23 462 484 462 484 0.97

5 8 1e-05 0.0013 20.1 0.5 1 23 490 512 490 512 0.98

6 8 0.00013 0.017 16.6 0.5 1 23 517 539 517 539 0.98

7 8 9.3e-05 0.012 17.0 0.5 1 23 545 567 545 567 0.97

8 8 0.015 2 10.1 6.4 1 23 573 596 573 596 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.7e-05	0.0022	19.4	1.8	1	23	370	393	370	393	0.96
2	8	1.3e-05	0.0018	19.7	0.6	1	23	402	424	402	424	0.99
3	8	0.0075	0.99	11.0	0.1	2	23	434	456	433	456	0.92
4	8	0.00044	0.058	14.9	0.0	1	23	462	484	462	484	0.97
5	8	1e-05	0.0013	20.1	0.5	1	23	490	512	490	512	0.98
6	8	0.00013	0.017	16.6	0.5	1	23	517	539	517	539	0.98
7	8	9.3e-05	0.012	17.0	0.5	1	23	545	567	545	567	0.97
8	8	0.015	2	10.1	6.4	1	23	573	596	573	596	0.97

Sequence Information

Coding Sequence: ATGCTTGCCTCTAAAATACCACAAAAGGCAATAGTAGCAGAGGCGCGTACTGAGTCCAGTTCACCAACTAATGACATGGCTTGGAAACATTGGTGTCGATTATGTGCTAAAGAAGATGATGACAGTCATTTGTGTGTCTTTCCAGAAATCAATGAGCCCGGAAAATTAGTGGATAGTAGTTTAGCTACAACAATTGGCAAATTTTTCTGGGTTAATataaGACCAAACGACGGATTATCGAATTATGTATGCCTTGAATGTCACACATTAGTGACTTCATTGACGCAGTTTACGGAACGCGTTAATAAAGTACAGGCTATGTTCTGCGCATTACAAAATTCTGACCCTACTAGTACAATGAATCTGAGTGAAGTTAGACTACAATACGGTTTATTGGATATGGAATGGGATCATATAATAAAGTCTGAACGAGTCATTGAAAACAAGAAAACCAACAGTGAGAAACCAACCAGTGATGTTGGTGATTGGGAATTGGATGGTGAAGATAATAAAGAAGATACAGAAGAATTTGAgttacaagaaaataaaaaacgcaaagCTGGTGAAAATTTCTCCTTTGAACTTGTTAAGCGTGGAATTAAAAGAAAGCGACAAGATGTTGAACATGATGAAGTGGAAGATAATGAGGGAGACAATATGTTAACGTTTGGTGCACTAGTAGGCGAATCTGAAGAAGATACAgaagaacattttataatcgaaAATATGACAACAGAAGAAGAGCTTGATGATGCTGAGCTACTACGTCAATTAAGAGGAGATGATGATGAGGAGGAAGATGAAAATGAACAGTTACAAGATACAAAAAAGGAGGAACATGAAGacaaattgaaaagtgaaaacgcTGAAGAAGATTGTGAAAATTATAacttagaagaagaagaagaagatatagaaCAAAATGATGATACAGACGAATATGTTGGTGGTGAGAAGTCAGCTCAAGTGAATAAAATTGATTCAAGTAGTCGTGTGCGAAAGAAAAGACGAGGACGACAACCTAAATATCAAACAAGTACAGAACATGCACCAGACGAAGCCGAGTCCGATGATGATGCAAATGATAATTCACAAACATCATACAAATATGAGTGTAGCATATGTCAGAAGAAGTACAAAAATCCTACATCATATCGTAAACACATTATGGAAAAACATAACCAGGAACCAGATATACCCGATTTCAAATGTGAAACCTGCAATAAAATCTATCCAACAGAACGTCAGTTACAAATACATGCGCGCACACATCTCGCACTGGAGGACAAACTCGATATACCGTGTCCATATTGTGAACGTAAATTCACCAAAGTGTCTGTTATGCGGCAACATGTGCAGGGAATACATGAAAACAAGAAACCGTATATTTGCGACGAATGTGGGCGTTCATTAAAAACATTAGCGGCATTAGCCGAGCATAAGCTAGTGCATACCAATGATACACCATTCGAATGCGAAGTGTGCCAGCGAGCTTTCAAGAATAAAGCACGATTAAAggtACATTTGGAGACACACAATGACTCCTCCTACATCTGCACAGAGTGCGGCCTTAAGTTGAACACGCGACGTACATTAAAAATGCACATGCTCGTGCATTCGGATGCCAAACGTTACAAGTGTGATTTCTGTCCTGCCGCATTTAAACGCACTAAAGCATTGAAAAATCACTTAATCCTACACACCGGCATGCGGCCATACAAGTGTAATTTCTGTGAGAAAACCTTTTCGAATGGCTCCAATTGTCGTTCGCACAAAAAGAAAATGCATGCACTAGAGTTGGCCGAAGAAGAGGCAATGGGTAAGAAAGCCGAAGCTGTAACAGTGCCGAAATTGGAGGAGCTGCGTTCGAGCACCAATGTTGTTGGCAATCCGCGTCGTGTGCAGCGTCATCAGGGCGGTTTACCGTTGCATATGCGACAATTGTTAATCGCAGCTGAGGAGCGCGCAAAACGTGACGAAACCACGAAGCACACGAATGGCACACAATCCAATGCTACACTTGAAATGCACGAGGAAGACACAGAAACACATTCGAAGGCGGTTTCTACAATACATTTAGAGGGTGACGACGACTCAGAGTTTATTGAATTGAATGAAGATTTGCTGCgtgatgacgatgacgatgatgagGAAGAGGATGATAATGAAATGGTTGTATATGAAATAATTGCTGAAATATAA
Protein Sequence: MLASKIPQKAIVAEARTESSSPTNDMAWKHWCRLCAKEDDDSHLCVFPEINEPGKLVDSSLATTIGKFFWVNIRPNDGLSNYVCLECHTLVTSLTQFTERVNKVQAMFCALQNSDPTSTMNLSEVRLQYGLLDMEWDHIIKSERVIENKKTNSEKPTSDVGDWELDGEDNKEDTEEFELQENKKRKAGENFSFELVKRGIKRKRQDVEHDEVEDNEGDNMLTFGALVGESEEDTEEHFIIENMTTEEELDDAELLRQLRGDDDEEEDENEQLQDTKKEEHEDKLKSENAEEDCENYNLEEEEEDIEQNDDTDEYVGGEKSAQVNKIDSSSRVRKKRRGRQPKYQTSTEHAPDEAESDDDANDNSQTSYKYECSICQKKYKNPTSYRKHIMEKHNQEPDIPDFKCETCNKIYPTERQLQIHARTHLALEDKLDIPCPYCERKFTKVSVMRQHVQGIHENKKPYICDECGRSLKTLAALAEHKLVHTNDTPFECEVCQRAFKNKARLKVHLETHNDSSYICTECGLKLNTRRTLKMHMLVHSDAKRYKCDFCPAAFKRTKALKNHLILHTGMRPYKCNFCEKTFSNGSNCRSHKKKMHALELAEEEAMGKKAEAVTVPKLEELRSSTNVVGNPRRVQRHQGGLPLHMRQLLIAAEERAKRDETTKHTNGTQSNATLEMHEEDTETHSKAVSTIHLEGDDDSEFIELNEDLLRDDDDDDEEEDDNEMVVYEIIAEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00193007;
90% Identity: iTF_01563989;
80% Identity: -