Basic Information

Insect: Zeugodacus cucurbitae
Gene Symbol: Zfy1
Assembly: GCA_028554725.2
Location: CM053021.1:922958-925187[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.2e-05 0.0029 19.0 3.5 1 23 267 289 267 289 0.96

2 11 0.00028 0.037 15.5 3.4 1 21 295 315 295 318 0.96

3 11 3.6e-05 0.0047 18.4 0.3 1 23 324 346 324 346 0.97

4 11 2.1e-06 0.00028 22.2 1.2 1 23 352 374 352 375 0.95

5 11 1.6e-07 2.1e-05 25.8 0.3 1 23 382 404 382 404 0.98

6 11 0.0014 0.18 13.4 1.0 1 23 410 433 410 433 0.96

7 11 0.16 22 6.8 0.1 1 23 439 460 439 460 0.94

8 11 0.00053 0.07 14.7 2.8 1 23 466 488 466 488 0.98

9 11 7.4e-05 0.0097 17.4 0.7 1 23 494 516 494 516 0.99

10 11 0.0027 0.36 12.4 0.7 1 23 522 547 522 547 0.96

11 11 0.00022 0.029 15.9 0.4 1 21 553 573 553 574 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.2e-05	0.0029	19.0	3.5	1	23	267	289	267	289	0.96
2	11	0.00028	0.037	15.5	3.4	1	21	295	315	295	318	0.96
3	11	3.6e-05	0.0047	18.4	0.3	1	23	324	346	324	346	0.97
4	11	2.1e-06	0.00028	22.2	1.2	1	23	352	374	352	375	0.95
5	11	1.6e-07	2.1e-05	25.8	0.3	1	23	382	404	382	404	0.98
6	11	0.0014	0.18	13.4	1.0	1	23	410	433	410	433	0.96
7	11	0.16	22	6.8	0.1	1	23	439	460	439	460	0.94
8	11	0.00053	0.07	14.7	2.8	1	23	466	488	466	488	0.98
9	11	7.4e-05	0.0097	17.4	0.7	1	23	494	516	494	516	0.99
10	11	0.0027	0.36	12.4	0.7	1	23	522	547	522	547	0.96
11	11	0.00022	0.029	15.9	0.4	1	21	553	573	553	574	0.96

Sequence Information

Coding Sequence: aTGGTGCGCAGTCGCCGCTCGTTGTCCAAAGAAGATGGTACATCGTTGCTTACCGACAGCGGTGTTTCGCTTTCGTCGCCACCCGCTGCGCGTACAGAGCACGGCGATGGCGAGGACGCGCAGGACTTGCATGCAGTGACCAACAAAAAAACAGTACGACGGCGCGTCGGTGGCACGAAAGCGACAAAAAGAGTACGGAAGGTCAAATCTGTGTCCACGGAAGCTACGACAGTGTCAAAGAAACAGAAAATTGGTTATTCAGCGGATTCAGCAGTTAGCGAAAGTAATTCAGCGCAGTTGGAAGATCACTTACCGGCCGTGGAAGCGCAATTGCTGCATGCGGAGACTAATTCAGCGCCTAAAAATGAGTCATCCACCACTTCGTCGGTTGAATTGGTTGTTGCAGCGGAAGCTGCAAGTACAGATGCAGCGCAGTCTACAGTTAATGAGACACAGGAAGCAAACGATCTAACGAGTATACCAAATTTGAGCGCTGAGACTGTCAATCCAGCTTTTATTGTAATACCAGCTGCTGGCACTACGGTCGACTCGTTTAATACAGTGGATATAACTGAAAAACCCATACTTGTTGTAACGACCATTTTGGAGACCTCCATTTCGGTGGCTGACTCTGCTTTTTCCGAGACAGACGTTACACAATCGGCAGCCGATTTGTCGGATATCACCCATTCAGCGAATGACTCTGCAAATTCTATTGGCGATTCAGCCTCTGCTTCCGATGCGACGCTAACACCAGCCGCCAATAAGCGCTCGGGCAAAGTGTTCATGCGTAAGGTGCACATTTGCCACATTTGTTCGAAGCAATTTCGTGGCAATAACGATCTGCGTCGCCACATGCTCATCCATTCGGACGAGCGCCCGTATAAGTGCGAGCAATGTGGCAACTGCTACCGGCAAGCGGTTAACCTCAGGAATCACATCAACTGCGCCCACACGAATCAACGGCAGTTCGCTTGCGAGCAATGCCCGAAAATGTTTGCGGTGAAGGAGCGTCTGCGGCTCCACATGCGACTGCACTCGGGCGAGAAACCCTACGCTTGTCCGGAGTGTGATAAACGCTTTGCACGCGGCGGACATTTGAAGCAGCACATCATTAGCCATCACAAGGGCAGCACCAAACAGTATGTGTGTGAGAAGTGCTCCACCGCCTTTTCAACGCCCTCCAACTTGCGCGCCCACATGGATCGCCATGAGAATGGACCCGAACACTATTGTGAGATCTGTAAGGAGCACTTTCCCAACGAACCGGTACTCAAGGCGCACATTAATAAACTCCACTACAAGCTGGGCCAGTTCGACTGCGACATCTGCAAGGAGACCATCGAAGATGATGCGCTGGCCAATCACATGAAGACCCACACGAATGTGAAGACACATGTTTGCGAGGTGTGCAAGTCGTATTTCATGCAGAAGTCCCAGTACAATGTGCATATGCGCATGCACACTGGTGAGCGCCCCTATCAGTGTAGGATTTGCTGGCAAACTTACGCCTACTCCAGTGTCCTAAAGCTGCACATACGCAAGCACACTGGCGAGAAACCATTCCAATGCTTGATTTGTACGGACGTGGTCGCCTTCTCGCAGTTGGCTCACCTCAAGACACACATGAAGAAAATCCATAAGCAGACGAATCCCTACATGTGCGAAGGCTGCCACCAGTTCTTCAAAATCAAAGCGGAGCTTCAAGCGCATATGCAACAGTGCGACAGCTGCAATGTCGACGTGGAGGAGGAGAATGCCAAAAACAGTGACTTGCAAACACTGTCGCACCTACGCTTTCTTATGGCATTACTGCTGAAGAAAATCTCTTCGCAGCAAAAGCTGCAGAAATTGGGCTACGAAAAGCGACTTATCGACAATGTTGTCGTCGCCTCACTGAAGCTTGCCAATCGCAAAGCGTGCGAGGATCAATCGCTGACGGCAATCGAACGTATGCGTCGTAATGTTGAAGAATTCCTGAATTGGATTGTGCCGGCAAAGGCAATGGAGACATTTCGTCAAGAGCAACAATCCGTGGAGAATATATTGGATAAAATAGTCACCATGTATATGAAGCACAAGTGA
Protein Sequence: MVRSRRSLSKEDGTSLLTDSGVSLSSPPAARTEHGDGEDAQDLHAVTNKKTVRRRVGGTKATKRVRKVKSVSTEATTVSKKQKIGYSADSAVSESNSAQLEDHLPAVEAQLLHAETNSAPKNESSTTSSVELVVAAEAASTDAAQSTVNETQEANDLTSIPNLSAETVNPAFIVIPAAGTTVDSFNTVDITEKPILVVTTILETSISVADSAFSETDVTQSAADLSDITHSANDSANSIGDSASASDATLTPAANKRSGKVFMRKVHICHICSKQFRGNNDLRRHMLIHSDERPYKCEQCGNCYRQAVNLRNHINCAHTNQRQFACEQCPKMFAVKERLRLHMRLHSGEKPYACPECDKRFARGGHLKQHIISHHKGSTKQYVCEKCSTAFSTPSNLRAHMDRHENGPEHYCEICKEHFPNEPVLKAHINKLHYKLGQFDCDICKETIEDDALANHMKTHTNVKTHVCEVCKSYFMQKSQYNVHMRMHTGERPYQCRICWQTYAYSSVLKLHIRKHTGEKPFQCLICTDVVAFSQLAHLKTHMKKIHKQTNPYMCEGCHQFFKIKAELQAHMQQCDSCNVDVEEENAKNSDLQTLSHLRFLMALLLKKISSQQKLQKLGYEKRLIDNVVVASLKLANRKACEDQSLTAIERMRRNVEEFLNWIVPAKAMETFRQEQQSVENILDKIVTMYMKHK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00192964;
90% Identity: iTF_01563949;
80% Identity: -