Zhep004256.1
Basic Information
- Insect
- Zelleria hepariella
- Gene Symbol
- topi
- Assembly
- GCA_949319315.1
- Location
- OX439379.1:33147749-33161122[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 9.7 5.3e+02 1.8 0.5 1 23 222 246 222 246 0.81 2 13 6.5e-05 0.0035 18.1 1.5 1 23 253 275 253 275 0.97 3 13 1.1 63 4.7 1.3 1 20 315 334 315 335 0.93 4 13 0.013 0.72 10.8 4.7 1 20 340 359 340 362 0.94 5 13 0.00021 0.011 16.5 2.6 2 22 371 391 370 395 0.92 6 13 0.65 35 5.5 2.5 1 23 403 426 403 426 0.86 7 13 1.3e-05 0.00071 20.3 0.6 1 23 432 455 432 455 0.95 8 13 4.8e-06 0.00026 21.7 2.1 2 23 468 489 467 489 0.97 9 13 0.0035 0.19 12.7 0.1 1 23 495 518 495 518 0.93 10 13 1.9e-06 0.00011 22.9 1.9 1 23 533 556 533 556 0.96 11 13 6.5e-05 0.0035 18.1 1.0 1 23 562 585 562 585 0.91 12 13 1.2e-06 6.4e-05 23.6 2.7 1 23 593 615 593 615 0.99 13 13 0.85 47 5.1 4.1 1 23 623 646 623 646 0.95
Sequence Information
- Coding Sequence
- ATGATAAATCGAAAACAATCTCACTCCCACCAGTACATCAAATATCTGCAAACTGAGGGCAAGCTCCGCGCGTGTTGGCACTGCCAAGCCAAAGTCAACAACTTCGCCAAATTTGCACTTAGTGCCCAGAAGAGTGTGCGAATACTGAAAGACTATTTGTCTGCCAATGAGGTGCCACCGACGTTGCAGCCCAGTCTGTGCATAACTGAAGTGGAGATTGTTGACATAGCACCGTTCCCATTGAAGCCTGAGCCAGAGGGCAGCCAGCTCACCAAGGATGAGCCCCATGGAGATAAGAGCATCCATTCTGAGCTGATAAAGCTCTCAAAAGAAGGCATCAAACTCGAAGAAGATTCACCTGATGATGACTATTCCGACGGAGACTTCCCAGTGCAAGAAAAGGAGGTGATAAAAAAGGAGAGGGTGGTGGAAGTTCAACCTCCAAAGGCTCCAGTGAAGAAAGAAGTGGCCGCGAAGAAGAAGAGCTTGAAGACTGTGAACACAAAAAAGAGCATAACCAAACAaaaattaatcaaaaagaaGAGCGCTAAAACTAAATCTAAGGGCGCAGCCAAGCAGGACGGTTGGTCGGTGCGGTGGGTGTCCAACGAGAAGGCGTCCAGTTGGTACGACGAGGAGAGAGCCGGCGAGACCGCCAGCAACTTCGCCTGCGCCCAGTGCAAGCGCGCCACCTTCAGCACCGAGGAACGGCTGGCGCAGCACTACACTGACAAACACGATGAAAGCGCCGGCGAGTTCCAGTGTAATGTATGCAAATACAGATTCAGAACGCTCTCGGTGCTGCGGCAGCACATCGAGCAACACTTCGTGGTGTACACGTGCCGCCTGTGCGCCTTCGAAGGGAGGAGCACCAAGTGCCTGCAGCAGCACTGCGCCGAGGCGCACAACCTGCGCGTCAAGAGAAGGACCAAGCCGACCTCCTACCTGTGCAAACGGTGCAAGGATACCTTCGCAACGTTCCACCTGCTCCGCGAGCACCGCGTGGACTGTAGCACGTACAAGTGTGCCAAGTGCGAGAAGAGTTTCAAGAACAAGTGCACCTACTTCGATCACTTGCCTCTGCACAAAGAAGGCGCCAAGGAGAAGCTCTATTGCCATGTGTGTGACAAGCAGTTCACGAGCGCGAGCTGGTTCAAGACGCACTTCCGCACCAGCCTCAAGCACGTCTCGCGTGACACCTTCCAACACGAGTGTCCGCACTGTCAGATGCGGTTCCACATCGCGCAGCGACTCAAGGAGCACGTCGCGGCCAAACATCTGAACCGAGGGCTCTACGCCTGCGACCTTTGTCCCAAGAGCTTCACTGTGAACAAGAGTCTGAAGAAGCACCGCGCGCGCGTGCACAACATCGGCTCCGTGGGCGTGCCCGTGCGCGACAAGGTCTGCGAACACTGCGGGAAGGCTTTCACGTCGACGACGTTCTTAAACGACCACATGCGCATGCACACCGGCGAGAAACCGTTCAAGTGTCAGCTGTGCCCCGCCGCCTTCGCGCAGAacggcaccctgtatatacacaCGCTCGGCGTGCACAAGAAGAAGCTGAGGAAGGACGGGCTGGCCGATTCGCCCTCGTACCAGTGTGAGGAGTGCGGCAAAGAGTTCTCGTCGAACAGTCAGATGCGGACGCACCACAAGCTGGCTCATCTCAAACAGAGCAACTTTGCCTGCGAGGCCTGCAACAAGGTATTCTCGTCGTCGACGCACCTCAAGAACCACCTGGCGGGGCGGCACGGCGTCCTCTCCAGCGACACCTTCAAGTGCGACACCTGCGGGAAGAGATACAACACAAACACGGCGCTGAAGACGCACATGAAGCGGCACGGCGGGCTCGGCGCCAGCCTGCACAAGTGCCGCGCGTGCGACGCTGAGTTCAAACACCTCACCGCACTGCACCTGCACTTCAAGATCATCCACCTCAAGCTCAAGAAGACCGACAAGGTCAGCCTCAAGAACATCGGCAACCCCGACAAGGAGCTCGTCATCAACGGGGAGGTGCAGAGGATAACGCCCTAG
- Protein Sequence
- MINRKQSHSHQYIKYLQTEGKLRACWHCQAKVNNFAKFALSAQKSVRILKDYLSANEVPPTLQPSLCITEVEIVDIAPFPLKPEPEGSQLTKDEPHGDKSIHSELIKLSKEGIKLEEDSPDDDYSDGDFPVQEKEVIKKERVVEVQPPKAPVKKEVAAKKKSLKTVNTKKSITKQKLIKKKSAKTKSKGAAKQDGWSVRWVSNEKASSWYDEERAGETASNFACAQCKRATFSTEERLAQHYTDKHDESAGEFQCNVCKYRFRTLSVLRQHIEQHFVVYTCRLCAFEGRSTKCLQQHCAEAHNLRVKRRTKPTSYLCKRCKDTFATFHLLREHRVDCSTYKCAKCEKSFKNKCTYFDHLPLHKEGAKEKLYCHVCDKQFTSASWFKTHFRTSLKHVSRDTFQHECPHCQMRFHIAQRLKEHVAAKHLNRGLYACDLCPKSFTVNKSLKKHRARVHNIGSVGVPVRDKVCEHCGKAFTSTTFLNDHMRMHTGEKPFKCQLCPAAFAQNGTLYIHTLGVHKKKLRKDGLADSPSYQCEECGKEFSSNSQMRTHHKLAHLKQSNFACEACNKVFSSSTHLKNHLAGRHGVLSSDTFKCDTCGKRYNTNTALKTHMKRHGGLGASLHKCRACDAEFKHLTALHLHFKIIHLKLKKTDKVSLKNIGNPDKELVINGEVQRITP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -