Basic Information

Insect: Zaprionus tsacasi
Gene Symbol: zfh1
Assembly: GCA_018904105.1
Location: JAEIFR010000295.1:2726315-2730513[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.5e-05 0.0017 18.5 1.0 1 23 150 172 150 172 0.97

2 15 0.0029 0.2 12.0 0.8 3 23 180 200 178 200 0.93

3 15 8.4e-05 0.0058 16.9 0.1 1 23 362 384 362 384 0.98

4 15 0.00079 0.054 13.8 2.2 1 23 390 412 390 412 0.98

5 15 2.9e-05 0.002 18.3 3.2 1 23 443 466 443 466 0.96

6 15 0.00056 0.039 14.3 1.9 1 23 499 521 499 521 0.95

7 15 0.016 1.1 9.7 1.4 1 23 527 550 527 550 0.97

8 15 0.025 1.7 9.1 0.4 3 19 559 575 558 576 0.95

9 15 0.00015 0.01 16.1 5.6 1 23 585 607 585 607 0.97

10 15 0.038 2.6 8.5 1.2 2 23 613 634 612 634 0.96

11 15 8.6e-06 0.00059 20.0 1.0 1 23 643 665 643 665 0.98

12 15 0.00097 0.067 13.5 0.1 3 23 673 693 671 693 0.97

13 15 5.2e-05 0.0036 17.5 0.5 1 23 699 721 699 722 0.95

14 15 0.048 3.3 8.2 0.4 1 23 732 754 732 754 0.97

15 15 0.0037 0.26 11.7 0.2 1 23 1296 1318 1296 1318 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.5e-05	0.0017	18.5	1.0	1	23	150	172	150	172	0.97
2	15	0.0029	0.2	12.0	0.8	3	23	180	200	178	200	0.93
3	15	8.4e-05	0.0058	16.9	0.1	1	23	362	384	362	384	0.98
4	15	0.00079	0.054	13.8	2.2	1	23	390	412	390	412	0.98
5	15	2.9e-05	0.002	18.3	3.2	1	23	443	466	443	466	0.96
6	15	0.00056	0.039	14.3	1.9	1	23	499	521	499	521	0.95
7	15	0.016	1.1	9.7	1.4	1	23	527	550	527	550	0.97
8	15	0.025	1.7	9.1	0.4	3	19	559	575	558	576	0.95
9	15	0.00015	0.01	16.1	5.6	1	23	585	607	585	607	0.97
10	15	0.038	2.6	8.5	1.2	2	23	613	634	612	634	0.96
11	15	8.6e-06	0.00059	20.0	1.0	1	23	643	665	643	665	0.98
12	15	0.00097	0.067	13.5	0.1	3	23	673	693	671	693	0.97
13	15	5.2e-05	0.0036	17.5	0.5	1	23	699	721	699	722	0.95
14	15	0.048	3.3	8.2	0.4	1	23	732	754	732	754	0.97
15	15	0.0037	0.26	11.7	0.2	1	23	1296	1318	1296	1318	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGATTATGGCGGCATCCGATGGATACAGCAGCACGCATCTGCGGTTGAGTCTGAGGTTGATATGCTGGAAAGCGGCGCACCCGACAGTGAGGTGACTGCTGCCTACTTGGTAAATGGGAATGCAACCGATGAAGATCTTGACCAAATGGCGGCCGAGAATCTAATCTTCATGGCGCGCGACGGTCAGCTGAGTGAAATTATAGCTGCCAACGAAACTGACGGCGAAACAGTTCTAATCACAGACAGCGGGACAGTGGAGTATGCAGAGTCATTCGACGATGATGCGCAGGTTGTAACCGAGGAAATAATAACTGATGATTGGGTACAGCATCAAGGCGCCGAACGTGTGGAAATCGCTGCTGAGCAAATTGCTGGCAATTCGAATTCCCTAGAGTTGCTGGATATGGAACAGGATGAATACACGGCGTTACGTCCTTATCCATGTGACTTCTGCAGTCGGCGTTTCCGCAAAAAGGCCAGCCTTAATAATCATATGCTGGCTCATCAAAACGATCGTCCACACCTGTGTAAACTGTGCGGTGCGCGTTTTTCACGTCGCGCTGAGCTCATAGGTCATTTTAAGGCACATGCTGTGGCTCAGGATGCAGCAGATGCGGAGGCCGCGGCAGCAGCTTCAATTAAATTTGAGCCCCAACTGCAGCAACATCGCCAAGGCGATGATCACTTCTATGAACAAGAATGGCCAATGTATCAGGATCAGGAGCATGAGCAAATACAGGATCAGGGACAGCAACTGGAGCAAGAGCATTTATCAGTAGCCAGTCAAGTTGTGCAACAAGCCAGCTATGCTTCCGTCAGCTCTGTGCAAGCTCCCACAGCAGCTCGTGGACGTATAAGTCGTCTGAAGCCCAAGGAGGAGACCACACAGTACATTGTGATTACTGACAAGCAGGCAACAGACGATATGCAACAGTATATGCATTGTGATGAGCTACAATCACCCCTAGCCGACAGTGCAACATCCACCAATGCGATGAACCCTATGGACAGCAGCCAAGCTGTTGAAGCAGTAGACGGTTCTCGTTATCCGGTTTTGGATGACAGCAAACCCTTTGTTTGTCAACAGTGTGGATTGGCATTTGCTCGCGAGAAGGCGCTTGTCTCGCACATTAAGAATCATCGCATGGACTCCCCCTTCGAATGCAATCAATGTCAGGAAATGTTTTGGGACAATCACAGTCTGCAGGAGCATCAGAAAACACATCAGTTTGAGGAGAGCAATTCAGAGTACGATCCAGCCTCGGCGGGTGAGGATAGTGCCAGTGAATCGGAGCCAGATCAGCTTTATGGCGACTTCTACTGCAGCGAGTGTGGTATTTCGTTTCATCGCCAAGATTTGCTGCGTAGGCACACCAAACAACAGCATAAGCTTGGCAACGCGGGAAGTGCGGCGGCTGCTCATCAAGCAACAGATGTGGAGGGCAGTGCTGATGCGGAAGCTGATAATGCCAAAGATGCACCACACTGCTGTCACACCTGCGGTAAATCGTTTCCTAGCGCATTGGAACTGCTTGCTCATGCAGAGATTCACGCACGCTTTCCCCCCTTCAAATGTGTCTTGTGTGGAATTAGTTTTTACGAGGAGCAGGGCATCAAACGCCATCTGCACACCCGTCATCCGCACGAGCTTAAGCCAAATTCATGCGTGCTGTGCGGCAAGGAATGCCGCGATCGCAAGGCCCTGATCAAACACGCCTGGGATCATTCGCGTGAGAAGTGCCACTCGTGCTCAAAGTGTGGTAAAAACTTTCATAACAAAGCCCGCCTGAAGCGACATATGGCCTCGCATCGCGACAAGTCAGTGGTGTGCGAGGTGTGCCACGAGGAGTTCCCCGATGGCCGCACCCTTTCCAATCATCGTCATTCGCATAGCACTACCTCGCCGGGGAAACTATTTCCATGTCACGAGTGCGGCAAGACCTTTGGCTCACGCAGCTCGCAACAGATTCATGTGCGCATTCATACGGGAGAACGTCCATATGGTTGTCGGTACTGCTGGAAGGCCTTCGCCGATGGCGGCACACTACGTAAGCATGAGCGGATTCATACTGGCGAGAAGCCTTATGCCTGCAGCGTATGTCCACGAGCTTTCAACCAACGTGTCGTGCTGCGTGAGCACATACGTTCTCATCATTCGGGACTCGATGCTGTTCGGGGCACGTATCATTGTACTGTCTGCACAGCTGACTTATCGTCATCCAATGAGCTTATACAGCATCTCATCCAGCACAGCGACACAAACACAGCCAAACAGCGTCAGCCAATTACTGGTCCGCGCAAGTATAAGCGACGTAGGAAACTGCAACCACATGAGATTGCACACATGCGAGCCGAACACAAGGATGGCGAGGAATATGCCAGTGACATGGATCTCTGCGACCTAGATGTGGAAAATGTTGACGATCTCTTTGACGGAAACGATGCACCGCCACCCAAAAAGGAGAAGCGCAAGCGCAGTGCTGCCAGCCAAGCGAAAGCAGTGGCAAATGGCGTTGCAGGAAGTGTGCATAACAATGCCTCTGCTGTTAAGCAACCGGATCGACTCTGGGATGAGAAATTTGCACAGTCAAATGGCAATGCGAATGGCGGCGGTAATGGTCAGGCCTGTGATGATGCCTACAAAGGTTTCTATCAAATTGACTCGCTGCTGGTTGTTAATGATACAACGCTGCAGCCCGTGAGCTCATCAAGTAGTACCAATACGTCGAAGACGCGACGCAGTGGCAAGCAGCCGGCACAGATGCAGACGAACAATAGTAATAAGTCAGCAGCTGGAACTGCATCCGCAGTCGGTACAGGATCACCTGGTGGCGACGAGTGCAGCAAATCGAATTCTACCTCCATTTCAACAAGCAGTCGCAGCAGTAGCAGGAAGAAGGCTAGCAAGGCGTCCAAGAGTTTGGCAGCCACCGGCTCAACTTCCAACAGCAGCAGTAGCGCACGTCCACGCATGATACATACGGAAAAGTCACGTGTGCCACAGGAGAATGTCTCGAAGAAGACAGGCCGAGGCCGGACATACGTAACGCGCACGAACACAAGCGAGACCAGCCAGCTGGGTCTGGTTAAGTCAAGCAATGTCGCCAGTTCGCGCATAGTTGATGATTATGAAATAATTTCACCTGCCCTACAGCCTCCTAATCAGATTAGTTCCAGTCCATTGCATATAAAGCAGGAGCAAGAACAACAGCAGCGCGTGCAGCTGATGTACGATGATACGCATCTGTTGATCGATGCGGGACTGTTGCGCGAGAAGACGTACGAGAAGTTTAATCCCAGTATAGTCAATGATTTGGAGGAGATTCTGCGTAGCCCGCTCAAACATGATCGCAATGCACGGTTGCGTTTCACCAGCGAATCATCGACAACACCACAATTTCTTCCCGAGGAGGAACAGAATCTGATAAAAATCGAACCCACTTCGCCGGATTTACGTGAAATGGTCGAGAGCCAGCAACGTGTCACATCTGCAGGACATGGAGCCACACCCACATCCTCATCGTCATCGGCGCGCACATCACGGCACCTGCGTCAGCTCACTGCCAATTCTAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATTCCGCTTCCAGCTCCAAAAAGTCATCCAGTGTTGCTGCCAGCAGTAAGACGAGCTCGTATCTCAACTACGGCGTCGACTCGTACAATGTGAGTAGCGGTACGAATGCCAGCTCATCGGATGTTAGCTCCGGATTCTTTTCCATCTCTGAGGTGGTATCCGCAGCAGATGCTGCCGATGCGGCGGCCAAAGCGGCAGCTGCCAACAAATCTGAGCGCAGGACGCGATGCTTTGAGTGTGAGATGTGCTCGGCAAATTTTCCGGATCGCGCTCAGCTGCTGGAACATGTGCATATACACATCTGA
Protein Sequence: MNNQDYGGIRWIQQHASAVESEVDMLESGAPDSEVTAAYLVNGNATDEDLDQMAAENLIFMARDGQLSEIIAANETDGETVLITDSGTVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNSNSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELIGHFKAHAVAQDAADAEAAAAASIKFEPQLQQHRQGDDHFYEQEWPMYQDQEHEQIQDQGQQLEQEHLSVASQVVQQASYASVSSVQAPTAARGRISRLKPKEETTQYIVITDKQATDDMQQYMHCDELQSPLADSATSTNAMNPMDSSQAVEAVDGSRYPVLDDSKPFVCQQCGLAFAREKALVSHIKNHRMDSPFECNQCQEMFWDNHSLQEHQKTHQFEESNSEYDPASAGEDSASESEPDQLYGDFYCSECGISFHRQDLLRRHTKQQHKLGNAGSAAAAHQATDVEGSADAEADNAKDAPHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQGIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCTADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGEEYASDMDLCDLDVENVDDLFDGNDAPPPKKEKRKRSAASQAKAVANGVAGSVHNNASAVKQPDRLWDEKFAQSNGNANGGGNGQACDDAYKGFYQIDSLLVVNDTTLQPVSSSSSTNTSKTRRSGKQPAQMQTNNSNKSAAGTASAVGTGSPGGDECSKSNSTSISTSSRSSSRKKASKASKSLAATGSTSNSSSSARPRMIHTEKSRVPQENVSKKTGRGRTYVTRTNTSETSQLGLVKSSNVASSRIVDDYEIISPALQPPNQISSSPLHIKQEQEQQQRVQLMYDDTHLLIDAGLLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTSAGHGATPTSSSSSARTSRHLRQLTANSXXXXXXXXXXXXXXXXXXXXXXXXXSASSSKKSSSVAASSKTSSYLNYGVDSYNVSSGTNASSSDVSSGFFSISEVVSAADAADAAAKAAAANKSERRTRCFECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01552585;
90% Identity: -
80% Identity: -