Basic Information

Gene Symbol
-
Assembly
GCA_018904035.1
Location
JAEIFZ010000115.1:5276025-5282244[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.032 2.5 8.7 0.2 1 23 931 954 931 954 0.94
2 13 5.2 4e+02 1.7 0.2 1 23 1116 1138 1116 1138 0.91
3 13 0.00012 0.009 16.4 2.7 2 23 1141 1162 1141 1162 0.97
4 13 4.5e-05 0.0035 17.7 0.2 3 23 1170 1190 1168 1190 0.98
5 13 3.8e-07 2.9e-05 24.2 4.1 2 23 1197 1218 1196 1218 0.97
6 13 3.3 2.6e+02 2.4 0.4 5 23 1231 1249 1228 1249 0.95
7 13 0.88 68 4.2 5.4 3 23 1256 1277 1254 1277 0.93
8 13 0.094 7.3 7.2 0.2 2 23 1288 1308 1287 1308 0.96
9 13 3.6e-05 0.0028 18.0 0.4 1 19 1314 1332 1314 1336 0.95
10 13 1e-05 0.00079 19.7 0.5 1 23 1344 1366 1344 1366 0.98
11 13 6.7e-05 0.0052 17.1 7.6 1 23 1372 1394 1372 1395 0.96
12 13 0.00013 0.01 16.2 5.9 1 23 1400 1422 1400 1422 0.98
13 13 0.019 1.4 9.5 8.2 1 23 1428 1450 1428 1451 0.95

Sequence Information

Coding Sequence
ATGGTTGAAAGTATGCAGTGCCCCGTGTGCACCTTGTACCTGCATGCGGGTATGAATCTCTCCGATCATTTGGAGACACATCCCAAGGAGCAGGTGATCAAAGCCTTGGTGCAGATGACTATTGTTGGCAACAATGTGGCAGGCAGTTCCTTAGCTACAGCTGTGCTTTCTAGTGCTGCCGGTTGTGGCACAACAGATGGCGGTGGCACGCATTCATCGCTGCCTCCTCCGCCACCGCCTCCACTTCAGCTCTTTGCGCAACAGTCGACGACAACGCTGTCGCATCAGAAGCCCCCACCCGCCTATGGCGCCGCCATCAGGGCATCATCTGTGCTGCGTTATGCCGAATCACCTGTGGCCCACTACTTAGAGCGCGATAATGGCGACTTTATTGTTCAAGAGACGCCCAAGCATATTGTAGAATGCGTTGAAAAGGATGATGGTGAATTCTCTGTCATTGAACGCATCTATCAATCGCCACCCAGCGTGTTGCACATTCACGACGATGACGAAGACGACGACGAAGATGAGGAGGAGACGGAGGAGAAGGTGCACAACTGGACGCATAGCGAGGATGAGGATCAGTCCAATGTGTCACATACCCATGTGGAAGATGGCGATGATGAGCGCGAGGACAGCCGGAGTAGAGTGGGCGTTAAGCAGACAATGAAAAGAACATCGCGCAAAACTAAGTCCGGTGGAAGGATAAGCAAACGCACTTCCAAGCATCATCAGCATCAGCCAGTGGAGGATGAAGATGACTTCATGAGCGTCGGCAGCAGTTGTGCTGATAGTGACCATCAGTCCGAGCAGCAGCATCAACAGCCACAGACTGCCTCAACTGCAGCTGCTGCTGCCGCCAACAGTGGTGCCTCTTCCGCAGCGGGTAGTTCCAGCGGGGCCACCAAATCGAAAAAGAATCGCGTGACGGTGTTGAGTGATGTGCCACTGAATATGAATGAGTATTTGGATCTGGTTGGCAACATTGTGGCATCAAGTCGCATTGGTGCGGCTCGTCCGTTTGCTGCCGTAGCACCCATACCGCTACTTAAGGTAGAGAAGGAGGAGCCACTGGACGATTACGATGGCATGCAGGCCACACTGACACCGTTGTCCTCGACGACAATGTCGCTGCAGGCAATCAAAGTGGAAGTGGAGGCGACGAAACTTTTGCCGCAACGCTTTACAGCACCAGCGCAGCAGCGTGGACCCAAAAAATTAGTCATCAAACCAAAGGCTACAGCAACGGCTACAGCGACGTTGGCGTCGACAACGACTACAAAAAAGACTGATAACAACGCTACCAGCAGCAGCAGCAACGGCGGCAGCAAAATCAGCGTGGAATCTCTCAGCATATCAGCTAAAATGCAAGGTCCAACTGGGGAGCTGGTGCAGATTAAGAGCGAGCGTACGGAAGTGGCATCAGGAATTGGCAGTATATTGGAAAAGCATCTGACAACCAGCTATGCAGCTACACAAAACCAACAGCAGCAACTACAGCAACAATTGTCGCGTAAACATTCGTCTGTCAATGATGATGATGCGAGAGTGCTACTGGAATTTGCCAACTCAAATTCAAAGCAGCAGCAGACCCAATCGGGCACTACGTTTGTTGTGAATGCGGCAAGTTTTGCCTCGGCCGGATCCGTCTTTGCTGTCAATGCCAGCAGCAATGCCGTCGGCAGTACGAGTGCAAAGAAGGCAACCAATACGCAGGGAGAAGAATATATATTGCCCGATGATAACAATCTGGAAGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTTTGCCTCCTCCTCTCAGCAACAGCAGCAGGAACAAACTCAACACCAGCACCAGCCTCACCATCAGCCAACGTCGACAACGCAGGCGCATTTGCAGCCTCCGCAAGGCTTCAATGATTTTAATTTTTTGTACCACCACCAAAACAACTCAGCAATAACAGCAACAACTACAGCTTCCAATTTCACACAATTTGGTCTGCAACAGCAACAACAACCACAGCAACATGGATCAAGCGAAGCAACAAATGCTGCAACACTTGCCTCATCTTCAAGCAATTCATCAGCATTGGATCAAGATTCCTCTATGAATGCCACATTTCGTGTGGCTAGGCCACAGTCCACACTGGGCACCTGTGTGGCGGCGGTTGATAGTGATGCAAAATATTTGGATTTAGATACATGCAAGCGGGAACAGTTGAGCAACAGCAGCAGCCATTTGCCATCTGTCTCGGCATCTACATCAACCACGTCTTCTTCATTTGCTGCTGCCGCAACGGAGAGCAGTTTAGTGGGTGGTTTGGGTCTCAACATACGCACGGATGAGAAGATGCCAGCCAAAGGGGAAATATCTGAGCAGGAGAGCAATTGTGACATTGAGAACTCCTGGAGTCAATCGGTAGGTATGTACGGCGACATATCACAGCGTTACTTTAGAAATCAGTTCTCAGATGGATACAATCAACAGCTGGCCGATTGGCGTCAGGATTACTATCCGGCGCAAGATCTCAGTGGCCAACAATCACAGCAGGAGCAGCGTGAGCCCAAACGCACTTTTGATTTTAATGCAGTCGCTTCGGAGTATGTACAACCGGGTGATCTGGACGCCTCATCGAGCTCGGCGAGAAGCAACAATAATTTATTAGATGCTCAACCCACCACCTCATCGTCGTCATCGGCATTGCTGGCTGGTCCACCAATTGCCTCGACTTCTCGTGCCGCAGCCGAAGCAGAAGCAGCTGTTGCAGCTGCGTTGGCACAACGCAAACCACCGCGTCGCAAGATTTACAAGTGCCCGCATTGTGTGGCCATATTTGAAAAGCTGAAAGAGCGCAATGCTCATATGATCGGCGAGCACAATTATGTGCGTCAGAATCGGCGTTTAATCTGTACACAGCCATTGGTTAGTGGCTCGATTATCTCGCAGCCTCAGGATGGGCAACAGCAGCAGGCGCAGCAATTAACTCTGCAATCGGAGGCAAGCGATATTGGTACTCTGCAAGAAGATTCCAAGGATGGCATAGTGAAGATCAAGCAGGAACATTGTCAAGATAAACAAGACACGCCAGGGCAGATGCTTGATCAAATGGACCTACCCGATGTGAAGGATGCCGATTTACTCGATGTGAACGGTTCAAATGGACGCGATGCCGACATGAAACCACCGACAAGCACCACTGAAATTGATCAGAAGCCAACAATGGCACCATTGGCAATTACCACACCTGCTGCCAAGTTGGCGGCTCTTTATCGCATGCTTATTTCCTACAATGAATCGAAACTGGGGCAGGAGCGTAACAATCTCAGCGAACTGGAACAGAAGGCCATGGAAAAGTCTATATTTCTTTGCTATGTCTGTCGTACGGATTTCCCTTCAGTTAAACTCTACGATGCCCATTTAACGGAACATCCTGCCGAGTGTTTCACGTGTGGAAAGAAATTCTATCGCTGGAAGAACTTCTCATTGCATCTGAAGCGTCATCTTGGCTGGAAGGAGTTTGGTTGCTATGTCTGTGACAAGAAGTTCGTAGTGCGCAGCGCTCTGGTCGAGCACATGCGTATGCATACGGGGCTGAGCCCACTGAAGTGCAAGATATGTGGCAAAAAATTCAAACGTTATTCCAATTTGACGCAACATCGCAAGCGACACACCAAAATGATGGTGCGCAAAAAGGAATATGTTTGCCATTGCGGTGAAGTATTGCCGTCAAAGGCACGTTTTCTATGGCACAAGGAGACGCATGATCTGAAGCCCAAATGCTGTCCCTATTGCTGCGATCGTTTCGTGCACGCCAATTCCTTGCGCCGCCACATACGACTGGCGCATTCGGATAAGTTTGACTATGCCGAGCCAATGGAGTGTCCCATGTGCAAGCAGATATTCGCCAAGACATCCATAAAGGCGCATATGGCAACGCATTCGACAGATCCACAATACGATTGCGCAATCTGCAACAAAAGTTTCTCCACCAAATGGAATCTCAAAATACATTCGTGGGTGCATGCGAATCGCACAGCCAAACCCTTCAAGTGCGAGTACTGTCCCAAGGCGTTTGTGCGTGAACTGGATTTTAAGAACCATATGAATGCACACAAGCAGATCAAACCGTACACCTGTGAGTATTGTGGCTGCAAGTTCATACGCAAGTACAACTATATGCGGCATCGGCGGGAGCATCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAATCCTTCCATCGGCATTACTATCTGATCGAGCATCGACGTATTCATACCGGGGAAAGACCCTTCCATTGCACGATTTGTGGCAAAAGCTCCACCACGAAAACCAATCACAACAAGCATCTGAAGATTCATCATTCGCGCGATCCCTTCACAGTGGAGGTCTAA
Protein Sequence
MVESMQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNNVAGSSLATAVLSSAAGCGTTDGGGTHSSLPPPPPPPLQLFAQQSTTTLSHQKPPPAYGAAIRASSVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEDDDEDEEETEEKVHNWTHSEDEDQSNVSHTHVEDGDDEREDSRSRVGVKQTMKRTSRKTKSGGRISKRTSKHHQHQPVEDEDDFMSVGSSCADSDHQSEQQHQQPQTASTAAAAAANSGASSAAGSSSGATKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLLKVEKEEPLDDYDGMQATLTPLSSTTMSLQAIKVEVEATKLLPQRFTAPAQQRGPKKLVIKPKATATATATLASTTTTKKTDNNATSSSSNGGSKISVESLSISAKMQGPTGELVQIKSERTEVASGIGSILEKHLTTSYAATQNQQQQLQQQLSRKHSSVNDDDARVLLEFANSNSKQQQTQSGTTFVVNAASFASAGSVFAVNASSNAVGSTSAKKATNTQGEEYILPDDNNLEVDEIVISSSSSFASSSQQQQQEQTQHQHQPHHQPTSTTQAHLQPPQGFNDFNFLYHHQNNSAITATTTASNFTQFGLQQQQQPQQHGSSEATNAATLASSSSNSSALDQDSSMNATFRVARPQSTLGTCVAAVDSDAKYLDLDTCKREQLSNSSSHLPSVSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSVGMYGDISQRYFRNQFSDGYNQQLADWRQDYYPAQDLSGQQSQQEQREPKRTFDFNAVASEYVQPGDLDASSSSARSNNNLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQPLVSGSIISQPQDGQQQQAQQLTLQSEASDIGTLQEDSKDGIVKIKQEHCQDKQDTPGQMLDQMDLPDVKDADLLDVNGSNGRDADMKPPTSTTEIDQKPTMAPLAITTPAAKLAALYRMLISYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGLSPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-