Basic Information

Insect: Zaprionus lachaisei
Gene Symbol: zfh1
Assembly: GCA_018901815.1
Location: JAEIFI010000587.1:176481-180680[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.4e-05 0.0017 18.5 1.0 1 23 149 171 149 171 0.97

2 15 0.00075 0.052 13.9 1.2 3 23 179 199 177 199 0.94

3 15 8.2e-05 0.0057 16.9 0.1 1 23 360 382 360 382 0.98

4 15 0.00076 0.053 13.8 2.2 1 23 388 410 388 410 0.98

5 15 3.1e-05 0.0022 18.2 2.2 1 23 441 464 441 464 0.95

6 15 0.00054 0.038 14.3 1.9 1 23 497 519 497 519 0.95

7 15 0.0098 0.68 10.4 1.3 1 23 525 548 525 548 0.97

8 15 0.024 1.7 9.1 0.4 3 19 557 573 556 574 0.95

9 15 0.00014 0.0099 16.1 5.6 1 23 583 605 583 605 0.97

10 15 0.037 2.6 8.5 1.2 2 23 611 632 610 632 0.96

11 15 8.3e-06 0.00058 20.0 1.0 1 23 641 663 641 663 0.98

12 15 0.00094 0.066 13.6 0.1 3 23 671 691 669 691 0.97

13 15 5e-05 0.0035 17.6 0.5 1 23 697 719 697 720 0.95

14 15 0.046 3.2 8.2 0.4 1 23 730 752 730 752 0.97

15 15 0.0036 0.25 11.7 0.2 1 23 1274 1296 1274 1296 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.4e-05	0.0017	18.5	1.0	1	23	149	171	149	171	0.97
2	15	0.00075	0.052	13.9	1.2	3	23	179	199	177	199	0.94
3	15	8.2e-05	0.0057	16.9	0.1	1	23	360	382	360	382	0.98
4	15	0.00076	0.053	13.8	2.2	1	23	388	410	388	410	0.98
5	15	3.1e-05	0.0022	18.2	2.2	1	23	441	464	441	464	0.95
6	15	0.00054	0.038	14.3	1.9	1	23	497	519	497	519	0.95
7	15	0.0098	0.68	10.4	1.3	1	23	525	548	525	548	0.97
8	15	0.024	1.7	9.1	0.4	3	19	557	573	556	574	0.95
9	15	0.00014	0.0099	16.1	5.6	1	23	583	605	583	605	0.97
10	15	0.037	2.6	8.5	1.2	2	23	611	632	610	632	0.96
11	15	8.3e-06	0.00058	20.0	1.0	1	23	641	663	641	663	0.98
12	15	0.00094	0.066	13.6	0.1	3	23	671	691	669	691	0.97
13	15	5e-05	0.0035	17.6	0.5	1	23	697	719	697	720	0.95
14	15	0.046	3.2	8.2	0.4	1	23	730	752	730	752	0.97
15	15	0.0036	0.25	11.7	0.2	1	23	1274	1296	1274	1296	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGATTATGGCGGCATCCGATGGATACAGCAGCACGCATCTGCGGTCGAGTCAGAGGTTGATATGTTGGAAAGCGGCGCACCCGACAGTGAGGTGACTGCCGCCTATCTGGTAAATGGCAATGCAACCGACGAGGATCTCGATCAAATGGCGGCCGAGAATCTTATCTTCATGGCGCGCGACGGTCAGCTAAGTGAAATTATAGCTGCCAACGAAACCGGTGGCGGCACAGTCCTAATCACAGACAGCGGCACTGTGTATGCAGAGTCATTTGACGATGATGCACAGGTGGTAACCGAAGAGATCATAACCGATGATTGGGTGCAGCATCAAGGCGCCGAACGTGTGGAAATCGCTGCTGAGCAGATAGCTGGAAACTCAAATTCGCTGGAGTTGCTAGATATGGAACAGGATGAGTACACAGCATTACGCCCCTATCCGTGTGACTTCTGTAGTCGACGTTTCCGTAAGAAAGCCAGCCTTAACAATCATATGTTGGCCCATCAAAACGACCGTCCGCATCTGTGTAAACTGTGCGGGGCGCGTTTTTCACGTCGCGCCGAACTCATCAGTCATTTTAAGGCACATGCTGAAGCCCAGGATGCAGCAGACGCGGAGGCCGCGGCAGCAGCTTCAATTAAATTTGAGCCGCAACAGCAGCAACATCGACAAGTGGATGATCACTTCTATGAACAGGAATGGCCAATGTATCAGGAGCAGGACCACGAGCAAATACAGGACCAGGGACAGCAACTTGAGCAAGAGCATTTATCAGTAGCTAGTCAAGTTGTACAACAGGCCAGCTATGCTTCCGTCAGCTCTGTGCAAGCTCCGACAGCAGCGCGGGGACGCATAAGTCGTCTGAAACCCAAGGAGGAGACCACACAGTACATTGTGATTGACAAGCAGGCTGCAGACGATTTGCAACAGTATATGAATTGCGATGAACTGCAACCACCCCTGGCCGACGGTGCTACGTCCAGCGATGCGATGCACACCATGGACAGCAGCCAAGCAGTTGAAGCTGAAGACGCCTCACGCTTTCCCGTGTTGGACGAAAGCAAACCCTTTGTTTGTCAACAGTGCGGATTGGCATTTGCTCGCGAGAAGGCGCTTGTCTCGCACATTAAGAATCATCGGATGGACTCTCCTTTCGAATGCAATCAGTGCCAGGAGATGTTCTGGGATAACCACAGTCTGCAGGAGCATCAGAAAACACATCAATTCGAGGAGAGCAGCTCAGAGTACGATCCACCTTCGGCTGGTGAGGAAAGTGCCAGTGAATCGGAGCCAGATCAGCTTTACGGTGACTTCTACTGCAGCGAATGTGGTATTTCGTTTCATCGACAAGATTTGTTGCGCCGGCATGCTAAGCAACAGCATAAGCTGAGTAACGCGGGCAGTGTTGCGGCTGCTCATCATGCAGCCGATGTGGAGGTCAGTGCCGATGCGGAGGCTGATAATGCCAAAGATGCCCCACACTGTTGTCACACCTGCGGTAAATCATTTCCCAGCGCATTGGAACTACTTGCCCACGCGGAGATCCACGCACGCTTTCCACCATTCAAGTGTGTCTTATGTGGTATCAGTTTCTACGAGGAACAGGCCATTAAACGGCATCTGCACACTCGCCACCCTCACGAGCTTAAGCCAAACTCATGCGTGCTGTGCGGCAAGGAGTGTCGCGATCGCAAAGCACTGATCAAACACGCCTGGGATCATTCGCGTGAGAAGTGTCATTCGTGCTCAAAGTGTGGTAAGAATTTTCACAACAAAGCCCGCCTGAAGCGCCACATGGCTTCGCATCGCGACAAGTCGGTGGTGTGCGAGGTGTGCCACGAAGAGTTTCCCGATGGGCGCACCCTTTCCAATCATCGACATTCGCACAGCACAACCTCGCCGGGGAAACTGTTTCCCTGCCACGAGTGCGGCAAGACCTTCGGCTCTCGCAGCTCGCAGCAAATTCATGTGCGCATTCATACGGGAGAACGTCCGTATGGCTGTCGGTACTGCTGGAAGGCTTTCGCCGATGGCGGTACACTGCGCAAGCATGAGCGGATTCATACGGGCGAGAAGCCTTACGCCTGTAGCGTGTGTCCGCGAGCTTTCAATCAACGTGTTGTGCTGCGTGAGCATATACGCTCACATCACTCGGGGCTTGATACAGTCCGCGGGACGTACCACTGCACAGTTTGCACAGCCGACTTATCCTCATCCAATGAGCTTATACAGCATCTCATTCAGCACAGCGACACAAACACAGCCAAACAGCGACAGCCAATTACTGGTCCGCGCAAATACAAGCGACGAAGGAAACTGCAACCACATGAAATTGCACACATGCGTGCCGAGAACAAGGATGGCGACGAATATGCCAGTGACATGGATCTCTGTGACCTGGATGTGGAGAATGTGGACGATCTCTTTGACGGAGCTGAAGCCCCGCCACCCAAAAAGGAAAAGCGCAAACGGAGCGCTCCCAGCCATGCGAAGGCAGTGGCAAATGGCGTAGGAGGACATGAGGATACCACGGCCTCTACAGTTAAACAAGCAAACAACAATCCAGATCGTCTGTGGGATGAGAAATTTTCGCAGTCAAATGGCAACGCGACTGGCGATGTTAATGGTCAGGTCTGTGATGAAGCATATAAAGGTTTCTATCAAATTGATTCGCTGCTGGTTGTTAATGATACAACGCTGCAACCCGTCAGCTCATCCAGCAGTACCAACACGTCGAAGACGCTACGCAGTGGCAAACAGTCGGCACAGACATTAATGCAGGCGAACAATAGCAACAAGTCAATAACGGCGGAATCAGGAACGTCATCAATAGCCAGAACAGCATCACCTCGTGGTGACGACTGCAGCAAATCGAACGCTACCTCAATTTCAACAAGCAGTCGAAGCAGCGGCAGAAAGAAGAATGGCAAGGCGGGCAAGAGCTTAGGAACAACCGCCTCAGCTTCCAACAGCGGCAGTAGTGCACGCCCACGCATGATACACACGGAAAAGTCACGTGTGCCACAGGAAAATGCCTCAAAAAAGGTCGGCCGAGGCCGTGGGTATATAACGCGCACGAGCACCAACGAGACCACCCAGCTGGGTCTGGTTAAGTCGAGCAGCGTCGCCAGTTCGCGCATTGTGGATGACTATGAGATAATTTCACCTGCCTTACAGCCCCCCAATCAGATTAGTTCTAGTCCATTGCATATAAAACAGGAGCAAGAACAACAGCAGCGCGTGCAGCTAATGTACGATGATACGCATCTGTTGATTGATGCAGGACTGTTGCGCGAGAAGACCTACGAGAAGTTTAATCCCAGCATAGTCAATGATCTAGAGGAGATTCTGCGTAGTCCGCTTAAGCACGATCGCAATGCTCGGCTGCGTTTTACCAGCGAATCATCGACAACACCACAATTTTTGCCCGAGGAGGAACAGAATCTGATAAAAATCGAGCCCACGTCCCCGGATTTGCGTGAAATGCCCGCACATCACGACACCTGCGTCAGCTCACTGCCAACTCCAGTTTTCGGGCGACAACAAAGCGCGGCAGCAGCAAAACCGTTTCCCCCCTCCAGCTCCAAAAAGTCAGCATTGTCCTCGTCGACCGCTGTTACAGCCAGCAAAACCAGCACGTATCTCAACTACGGCGTCGACTCGTACAACGTGAGTAGCGGTACGAATGCCAGCTCATCGGATGTAAGCTCCGGATTCTTCTCCATCTCCGAGGTTGTATCCGCAGCAGATGCCGCCGATGCCGCAGCCAAAGAGGCAGCGGCCAACAAATCTGAGCGCAGGACGCGATGCTTTGAGTGCGAAATGTGCTCCGCCAACTTTCCGGACCGCGCTCAGCTGCTGGAGCATGTGCATATACACATCTGA
Protein Sequence: MNNQDYGGIRWIQQHASAVESEVDMLESGAPDSEVTAAYLVNGNATDEDLDQMAAENLIFMARDGQLSEIIAANETGGGTVLITDSGTVYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNSNSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAASIKFEPQQQQHRQVDDHFYEQEWPMYQEQDHEQIQDQGQQLEQEHLSVASQVVQQASYASVSSVQAPTAARGRISRLKPKEETTQYIVIDKQAADDLQQYMNCDELQPPLADGATSSDAMHTMDSSQAVEAEDASRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRMDSPFECNQCQEMFWDNHSLQEHQKTHQFEESSSEYDPPSAGEESASESEPDQLYGDFYCSECGISFHRQDLLRRHAKQQHKLSNAGSVAAAHHAADVEVSADAEADNAKDAPHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDTVRGTYHCTVCTADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAENKDGDEYASDMDLCDLDVENVDDLFDGAEAPPPKKEKRKRSAPSHAKAVANGVGGHEDTTASTVKQANNNPDRLWDEKFSQSNGNATGDVNGQVCDEAYKGFYQIDSLLVVNDTTLQPVSSSSSTNTSKTLRSGKQSAQTLMQANNSNKSITAESGTSSIARTASPRGDDCSKSNATSISTSSRSSGRKKNGKAGKSLGTTASASNSGSSARPRMIHTEKSRVPQENASKKVGRGRGYITRTSTNETTQLGLVKSSSVASSRIVDDYEIISPALQPPNQISSSPLHIKQEQEQQQRVQLMYDDTHLLIDAGLLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMPAHHDTCVSSLPTPVFGRQQSAAAAKPFPPSSSKKSALSSSTAVTASKTSTYLNYGVDSYNVSSGTNASSSDVSSGFFSISEVVSAADAADAAAKEAAANKSERRTRCFECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01552585;
90% Identity: iTF_01556979;
80% Identity: -