Basic Information

Insect: Zaprionus kolodkinae
Gene Symbol: zfh1
Assembly: GCA_018901885.1
Location: JAEIFM010000498.1:9745095-9749333[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.6e-05 0.0018 18.5 1.0 1 23 150 172 150 172 0.97

2 15 0.0031 0.21 12.0 0.8 3 23 180 200 178 200 0.93

3 15 8.8e-05 0.006 16.9 0.1 1 23 362 384 362 384 0.98

4 15 0.00082 0.056 13.8 2.2 1 23 390 412 390 412 0.98

5 15 3.3e-05 0.0023 18.2 2.2 1 23 443 466 443 466 0.95

6 15 0.00058 0.04 14.3 1.9 1 23 500 522 500 522 0.95

7 15 0.017 1.2 9.6 1.4 1 23 528 551 528 551 0.97

8 15 0.026 1.7 9.1 0.4 3 19 560 576 559 577 0.95

9 15 0.00015 0.01 16.1 5.6 1 23 586 608 586 608 0.97

10 15 0.04 2.7 8.5 1.2 2 23 614 635 613 635 0.96

11 15 8.9e-06 0.00061 20.0 1.0 1 23 644 666 644 666 0.98

12 15 0.001 0.069 13.5 0.1 3 23 674 694 672 694 0.97

13 15 5.4e-05 0.0037 17.5 0.5 1 23 700 722 700 723 0.95

14 15 0.05 3.4 8.2 0.4 1 23 733 755 733 755 0.97

15 15 0.0039 0.26 11.7 0.2 1 23 1306 1328 1306 1328 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.6e-05	0.0018	18.5	1.0	1	23	150	172	150	172	0.97
2	15	0.0031	0.21	12.0	0.8	3	23	180	200	178	200	0.93
3	15	8.8e-05	0.006	16.9	0.1	1	23	362	384	362	384	0.98
4	15	0.00082	0.056	13.8	2.2	1	23	390	412	390	412	0.98
5	15	3.3e-05	0.0023	18.2	2.2	1	23	443	466	443	466	0.95
6	15	0.00058	0.04	14.3	1.9	1	23	500	522	500	522	0.95
7	15	0.017	1.2	9.6	1.4	1	23	528	551	528	551	0.97
8	15	0.026	1.7	9.1	0.4	3	19	560	576	559	577	0.95
9	15	0.00015	0.01	16.1	5.6	1	23	586	608	586	608	0.97
10	15	0.04	2.7	8.5	1.2	2	23	614	635	613	635	0.96
11	15	8.9e-06	0.00061	20.0	1.0	1	23	644	666	644	666	0.98
12	15	0.001	0.069	13.5	0.1	3	23	674	694	672	694	0.97
13	15	5.4e-05	0.0037	17.5	0.5	1	23	700	722	700	723	0.95
14	15	0.05	3.4	8.2	0.4	1	23	733	755	733	755	0.97
15	15	0.0039	0.26	11.7	0.2	1	23	1306	1328	1306	1328	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGATTATGGCGGCATCCGATGGATACAGCAGCACGCATCAGCGGTCGAGTCTGAGGTTGATATGCTGGAAAGCGGCGCACCCGACAGTGAGGTGACTGCTGCCTATTTGGTAAATGGGAATGCAACCGATGAAGATCTTGATCAAATGGCGGCCGAGAATCTAATCTTCATGGCGCGCGATGGTCAGCTGAGTGAAATTATTGCAGCCAACGAAACCGACGGTGAAACAGTTCTAATCACAGACAGCGGGACAGTGGAGTATGCAGAGTCATTCGACGATGATGCGCAGGTTGTAACCGAGGAAATAATAACTGACGATTGGGTTCAGCATCAGGGAGCCGAACGTGTGGAAATCGCAGCTGAGCAAATTGCTGGAAATTCGAATGCCCTAGAGTTGCTGGATATGGAACAGGATGAATACACGGCATTACGCCCTTATCCGTGTGACTTCTGCAGCCGGCGTTTTCGAAAAAAGGCCAGCCTTAATAACCATATGCTGGCTCATCAAAACGATCGTCCACACCTGTGTAAACTGTGCGGTGCGCGTTTTTCACGTCGTGCTGAGCTCATTGGCCATTTCAAGGCACATGCTGTGGCTCAGGATGCAGCAGATGCGGAGGCCGCGGCAGCAGCTTCAATTAAATTCGAGCCCCAGCTGCAGCAACATCGGCAAGGCGATGATCACTTTTATGAACAAGAATGGCCAATGTATCAGGATCAGGAGCATGAGCAAATACAGGACCAGGGACAGCAACTGGAGCAAGAGCATTTATCAGTAGCCAGTCAAGTTGTGCAACAAGCCAGCTATGCTTCCGTCAGCTCTGTGCAAGCTCCCACAGCAGCACGTGGACGTATTAGTCGTCTGAAGCCCAAGGAGGAGACCACACAGTACATTGTGATTACTGACAAGCAGGCAACAGACGATTTGCAACAGTATATGCATTGTGATGAGCTACAATCACCCCTAGCCGACAGTGCAACATCCACCAATGCGATGAACCCTATGGACAGCAGCCAAGCTGTTGAAGCGGTAGACGGTTCTCGTTATCCGGTTTTGGATGACAGCAAACCCTTTGTTTGCCAGCAGTGCGGATTGGCATTTGCTCGCGAGAAGGCGCTTGTCTCGCACATTAAGAATCATCGCATGGACTCTCCCTTCGAATGCAATCAATGTCAGGAAATGTTCTGGGACAATCATAGTCTGCAGGAGCATCAGAAAACACATCAGTTTGAGGAGAGCAATTCAGAGTATGATCCAGCCTCGGCGGGTGAGGATAGTGCCAGTGAATCGGAGCCAGATCAGCTTTATGGTGATTTCTACTGCAGTGAGTGTGGTATTTCGTTTCATCGGCAAGATTTGCTGCGTAGGCATGCCAAACAACAGCATAAGCTCGGCAATGCGGGGAGTGCGGCGGCGGCTGCTCAACATGCAACTGATGTGGAGGGCAGTGCTGATGCTGACGCTGACAATGCCAAAGACGGAACACACTGCTGTCACACCTGCGGTAAATCATTTCCCAGCGCATTGGAACTGCTTGCTCATGCCGAGATTCATGCACGCTTTCCTCCCTTCAAATGTGTCTTGTGTGGAATCAGCTTTTACGAGGAGCAGGGCATCAAACGCCATCTGCACACCCGTCATCCGCACGAGCTTAAGCCAAATTCATGCGTGCTGTGCGGCAAGGAATGCCGTGATCGCAAGGCACTGATCAAACACGCCTGGGATCATTCGCGTGAGAAGTGCCACTCGTGCTCAAAGTGTGGTAAAAACTTTCATAACAAAGCCCGCCTGAAGCGACATATGGCCTCGCATCGCGACAAGTCTGTGGTGTGCGAGGTGTGCCACGAGGAGTTTCCCGATGGCCGCACCCTTTCCAATCATCGTCATTCGCATAGCACTACCTCGCCGGGGAAACTTTTTCCATGTCACGAGTGCGGCAAGACCTTTGGATCACGCAGCTCGCAACAGATTCATGTGCGCATTCATACGGGAGAACGTCCATATGGCTGTCGGTACTGCTGGAAAGCCTTCGCCGATGGCGGCACACTGCGCAAGCATGAGCGGATTCATACGGGCGAGAAGCCTTATGCCTGCAGCGTATGTCCACGAGCTTTCAACCAACGTGTCGTGCTGCGTGAGCACATACGTTCTCATCATTCGGGACTCGATGCTGTTCGGGGCACGTATCATTGTACTGTCTGCACAGCCGACTTATCGTCATCCAATGAGCTTATACAGCATCTCATCCAGCACAGCGACACGAACACAGCCAAACAGCGTCAGCCAATTACTGGTCCGCGCAAGTATAAGCGTCGTAGGAAACTGCAACCACATGAGATTGCGCACATGCGTGCCGAAAACAAGGATGGCGAAGAATATGCCAGTGACATGGATCTCTGCGACCTAGATGTGGAAAATGTTGACGATCTCTTTGACGGAAATGATGCACCGCCCCCGAAAAAGGAGAAGCGCAAGCGCAGTGCTGCCAGCCAAGCGAAGGCAGTGGCAAATGGCGTTGCGGGAAGTGTGCATAACACTGCCACGGCTGTAAAGCAACCGGATCGACTCTGGGATGAGAAATTTGCACAGTCAAATGGCAATGCGAATGGCGGTGGTAGCGGTCAGGTCTGTGATGATGCCTACAAAGGTTTCTATCAAATTGACTCACTGCTGGTTGTTAATGATACAACGCTACAGCCCGTGAGCTCATCCAGTAGTACCAATGCGTCGAAGACGCGACGCAGTGGCAAGCAGGCGGCACAGTTGCAGACGAACAATAGTAACAAGTCATTAACGGCAGCAGCACGAACGACATCCGCAGCGGGTACAGGATCAGGACCTGGTGGCGATGCAGAGTGCAGCAAATCGAATTCTACCTCCATTTCAACAAGCAGTCGCAGCAGTAGCAGGAAGAAGGCTAGCAAGGCATCCAAGAGTATGGGAACAACCGGCTCAACTTCCAACAGCAGCAGCAGTAGCGCACGTCCACGCATGATACATACGGAAAAGTCACGTGTGCCGCAGGAAAATGTCTCGAAGAAGACTGGGCGAGGTCGGACTTATGTGACGCGCACGAACACAAGCGAGACCAGCCAGCTGGGTCTGGTGAAGTCAAGCAGCGTCGCCAGTTCGCGCATTGTTGATGATTATGAAATAATTTCACCTGCCCTACAGCCTCCCAATCAGATTAGTTCCAGTCCATTGCATATTAAGCAGGAGCAAGAACAACAGCAGCGTGTGCAGCTGATGTACGATGATACGCATCTGTTGATCGATGCGGGACTGTTGCGCGAGAAGACCTACGAGAAGTTTAATCCCAGTATAGTCAATGATTTGGAGGAGATTCTGCGTAGCCCGCTCAAACATGATCGCAATGCACGCTTGCGTTTCACCAGCGAATCATCGACAACCCCACAATTTCTTCCCGAGGAGGAACAGAATCTGATAAAAATCGAACCAACGTCGCCGGATTTACGTGAAATGGTCGAGAGCCAGCAACGTGTAACATCTGCTGGACATGGAGCCACACCCACATCCTCATCATCGTCATCGGCGCGCACATCACGGCATCTGCGTCAGCTCACTGCCAATTCTAGTTTTCGGACAGCAACCAAGCAGCGCGGTGGCAGCGGCACCAGCAGCAGTAATAACAGCCGAAGCAAAACAGATTCCTCCGCTTCCAGCTCCAAGAAGTCATCCACTGTTGCTGCCAGCAATAAAACGAGCTCGTATCTCAACTACGTCGGCGTCGATGCGTACAATGTGAGCAGCGGTACGAATGCCAGCTCATCGGATGTTAGCTCCGGATTCTTTTCCATCTCTGAGGTGGTATCCGCAGCCGATGCTGCCGATGCGGCGGCCAAAGCGGCTGCGGCCAATAAATCTGAGCGCAGGACGCGATGCTTTGAGTGTGAGATGTGCTCGGCCAATTTTCCGGATCGCGCTCAGCTGCTGGAACATGTGCATATACACATCTGA
Protein Sequence: MNNQDYGGIRWIQQHASAVESEVDMLESGAPDSEVTAAYLVNGNATDEDLDQMAAENLIFMARDGQLSEIIAANETDGETVLITDSGTVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNSNALELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELIGHFKAHAVAQDAADAEAAAAASIKFEPQLQQHRQGDDHFYEQEWPMYQDQEHEQIQDQGQQLEQEHLSVASQVVQQASYASVSSVQAPTAARGRISRLKPKEETTQYIVITDKQATDDLQQYMHCDELQSPLADSATSTNAMNPMDSSQAVEAVDGSRYPVLDDSKPFVCQQCGLAFAREKALVSHIKNHRMDSPFECNQCQEMFWDNHSLQEHQKTHQFEESNSEYDPASAGEDSASESEPDQLYGDFYCSECGISFHRQDLLRRHAKQQHKLGNAGSAAAAAQHATDVEGSADADADNAKDGTHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQGIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCTADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAENKDGEEYASDMDLCDLDVENVDDLFDGNDAPPPKKEKRKRSAASQAKAVANGVAGSVHNTATAVKQPDRLWDEKFAQSNGNANGGGSGQVCDDAYKGFYQIDSLLVVNDTTLQPVSSSSSTNASKTRRSGKQAAQLQTNNSNKSLTAAARTTSAAGTGSGPGGDAECSKSNSTSISTSSRSSSRKKASKASKSMGTTGSTSNSSSSSARPRMIHTEKSRVPQENVSKKTGRGRTYVTRTNTSETSQLGLVKSSSVASSRIVDDYEIISPALQPPNQISSSPLHIKQEQEQQQRVQLMYDDTHLLIDAGLLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTSAGHGATPTSSSSSSARTSRHLRQLTANSSFRTATKQRGGSGTSSSNNSRSKTDSSASSSKKSSTVAASNKTSSYLNYVGVDAYNVSSGTNASSSDVSSGFFSISEVVSAADAADAAAKAAAANKSERRTRCFECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01552585;
90% Identity: -
80% Identity: -