Basic Information

Gene Symbol
-
Assembly
GCA_018903695.1
Location
JAEIFO010001440.1:6868300-6869855[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 4.1e-06 0.00029 21.0 1.7 3 23 87 107 86 107 0.98
2 7 8.2e-06 0.00058 20.0 0.2 1 23 113 135 113 135 0.94
3 7 4.1e-06 0.00029 21.0 0.6 1 23 141 163 141 163 0.97
4 7 0.17 12 6.5 1.0 1 22 169 192 169 195 0.86
5 7 3.7e-06 0.00026 21.1 1.6 1 23 226 248 226 248 0.99
6 7 3.3e-06 0.00023 21.3 1.4 2 23 255 278 254 278 0.93
7 7 0.019 1.3 9.4 5.4 1 23 284 306 284 306 0.98

Sequence Information

Coding Sequence
ATGCGTCAACCCGAACAGCCTTTAGGGCCAGAGGCCCAGGGGGAGGAGGAGGAGGAGGAGGAGGACAACGATTGTTATGCCGCCTGTCTGACCGAGGATCTGCAGCTCTTTGGGCAACTAAACGATCTGCAAGCTCAGGATCTTCTTCAGCTGACAAATGTGACTCCTTTGCCATCGCCGTCATCTGTGGCATCAACAGACTTGCCACCTGTCCGTCGCAAACGTGCTGCGCCCACAAAGCGAATGACGCGCAACATTTGTGACATTTGCACGCGTTGCTTTAGTGACGCTTATACGTTGCGCATTCACCGGATGACGCACACCGATGAGCGTCCACATGTGTGCGGGGAGTGCGGCAAGGGATTCCGACAGCTGAGCAAACTGCGCATTCACGCCGTAATACACACCAAGGAGCGGCCCCACGAGTGTGACATCTGTGGCAAGGGATTCCGTTTTGCCAACTACCTTGCCGTCCATCGGCGACTGCATACGGGCGAGAAACCCTATGCGTGCACAGTGCCGGAATGCGGCATGAGCTTTCATTCCATACACGCTCGCCGCATGCACCTCAAGCTGCAGCAGCATGATTGCAAGACAACAGAGATGCCAGTGAAGCAAGACGAGCAGGAGGAGCAGGAGGAGCAGCTAGCGTCTGGATCTGTAGCCTCGCTCAGCTACACCTGCCCCATCTGCGGGCGCATCCTCACCGATCAATGCTATCTAAATACGCACCTAAAGCGTCACTACAACCAACGCGACTTCCTCTGCCCGCAGCCGCAGTGCGGCAAGCGTTTCTTTAGCTCATCCGAACTGAACCATCATCAGATCACCCATATACGACTGCGTCCGTTTCGCTGCGTCCACTGCACGTCGCGATTCCTACGCAAATCGAATTACCAGCAGCATCTCAAGCTGCATCAAGCTGAAGCCTGA
Protein Sequence
MRQPEQPLGPEAQGEEEEEEEDNDCYAACLTEDLQLFGQLNDLQAQDLLQLTNVTPLPSPSSVASTDLPPVRRKRAAPTKRMTRNICDICTRCFSDAYTLRIHRMTHTDERPHVCGECGKGFRQLSKLRIHAVIHTKERPHECDICGKGFRFANYLAVHRRLHTGEKPYACTVPECGMSFHSIHARRMHLKLQQHDCKTTEMPVKQDEQEEQEEQLASGSVASLSYTCPICGRILTDQCYLNTHLKRHYNQRDFLCPQPQCGKRFFSSSELNHHQITHIRLRPFRCVHCTSRFLRKSNYQQHLKLHQAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01549064;
90% Identity
iTF_01554160;
80% Identity
-