Basic Information

Gene Symbol
-
Assembly
GCA_018903715.1
Location
JAEIGL010000003.1:4017764-4024017[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.032 2.2 8.8 0.2 1 23 877 900 877 900 0.94
2 13 5.1 3.6e+02 1.8 0.2 1 23 1062 1084 1062 1084 0.91
3 13 0.00011 0.008 16.4 2.7 2 23 1087 1108 1087 1108 0.97
4 13 4.4e-05 0.0031 17.7 0.2 3 23 1116 1136 1114 1136 0.98
5 13 3.7e-07 2.6e-05 24.3 4.1 2 23 1143 1164 1142 1164 0.97
6 13 3.3 2.3e+02 2.4 0.4 5 23 1177 1195 1174 1195 0.95
7 13 0.86 60 4.2 5.4 3 23 1202 1223 1200 1223 0.93
8 13 0.092 6.4 7.3 0.2 2 23 1234 1254 1233 1254 0.96
9 13 3.5e-05 0.0024 18.1 0.4 1 19 1260 1278 1260 1282 0.95
10 13 1e-05 0.0007 19.8 0.5 1 23 1290 1312 1290 1312 0.98
11 13 6.6e-05 0.0046 17.2 7.6 1 23 1318 1340 1318 1341 0.96
12 13 0.00013 0.0089 16.3 5.9 1 23 1346 1368 1346 1368 0.98
13 13 0.018 1.3 9.5 8.2 1 23 1374 1396 1374 1397 0.95

Sequence Information

Coding Sequence
ATGGTTGAGAGCATGCAGTGCCCCGTGTGCACCCTATACCTGCATGCGGGTATGAATCTCTCCGATCATTTGGAGACACATCCCAAGGAGCAGGTGATCAAGGCTCTGGTGCAGATGACTATTGTTGGCAACAATGTGGCAGGCAGTTCCTTGGCTACAGCTGTGCTCTCTACTGCCGCCGGTTGTGGCACAACCGATGGCAGTGGCAGCGGTGGCAGCACATCCTCCACTTCCTCATCGGCCATGTCCTTCGCGCCACCCCCGACTGAGGCGCTAGCAGCCACCACATCCAACGCACCCACCACAAGCAGCAGCGTGGCCACAGTCTATCCGCCAACGTTGACCTCTGACTATCGCTATGAGCAGCAGCCGCCACCACCGGCAACATCGCTACATGGATTTGCGCGTGGCAGCAACACGTCGCTAGTGATACCACATCCGCCACAGCAGCAGCAACAACATTTTCTGACCAACCAACAGCAGCCTGGACACTTCGCTGCCCAACAACAACAACAACAGTCGCCAATGAAGTACGCATATGCAGCGCATGCAACGCTGCCTCCTCCGCCACCGCCTCCACTGCAGCTCTTTGCGCAACAGTCGACGACAACGTTGTCGCATCAGAAGCCCCCACCCGCCTATGGCGCCGCCATCACTGCACAACATAACGTTAACCTTGCACCACCGAGCGGGAAACACAGCAAAATCCACACGGATATCTTTCTGAATCCACCGCCACCACCACCGCCACAGTCCACATTGCCGACGTCGTCTGGACGCAATATCAGCAGCCGCCAATCGACCAATTCGCCATTTGGAGCACTGTTAAATGCTGCCGCACAAGCTGCCTACGTTCCACCTGCCGCAGGGGCACCATCTGTGCTGCGTTTTGCCGAATCACCTGTGGCCCACTACTTGGAGCGCGATAATGGCGACTTTATTGTGCAAGAGACTCCCAAGCATATTGTGGAATGCGTTGAAAAGGAGGATGGTGAATTCTCAGTCATTGAACGCATCTATCAATCGCCGCCCAGCGTGTTGCACATTCACGACGATGACGAAGACGACGACGATGACGAAGATAAGCAGGAGACGGAGGAGAAGGTGCACAACTGGACGCATAGCGAGGATGAGGATCAGTCCAAGGTGTCACATGGTCATGTGGATGATGGCGATGATGAGCGCGAGGACAGCCGCAGTAGAGTTGGCGTCAAGCAGACAACGAAAAGAACATCGCGCAAAACTAAATCCGGTGGAAGGATAAGCAAACGCACTTCCAAGCATCATCAGCATCAGCCAGTGGAGGATGAAGATGACTTCATGAGCGTCGGCAGCAGTTGTGCCGATAGTGACCATCAGTCCGATCAGCTGCATCAACACCATCAACAGCCACAGAATGCCTCAAGTGCTGTACTGGCATCGTCATCATCCTCATCATCTGCACAGCATCTTTCCACGGCACCCTCAACCTCAGCTGCAGCTGCTGCCGCCGCCAACAGTAGTGGTGCCTCATCTGCAACGGGTAGTTCCAGCGGGGCCACCAAGTCGAAGAAGAATCGTGTGACGGTGCTGAGTGATGTGCCGCTGAATATGAATGAGTATTTGGATCTGGTTGGCAACATTGTGGCATCAAGTCGCATTGCTAAAGTGCAAGGGCCAACTGGGGAGCTGGTGCAGATCAAGAGCGAACGTACGGAAGTGGCATCAGGCACAGGCAGTATTTTGGAGAAGCATCTGACCACCAGCTATGCAGCTACACAACACCAGCAGCAGCAGCAACTACAGCAACAATTGTCGCGTAAACATTCGTCTGTCAATGATGATGATGCGCGAGTGCTACTAGAATTTGCCAACTCCAATTCAAAGCAGCAGCAGACCCAATCGGGCACTACGTTTGTTGTGAATGCGGCAAGTTTTGCCTCGGCCGGATCCGTCTTTGCGTCCAGCAGCAATGCCGTCGGCAGTCCGAGTGCAAAGAAGGCAAACACTTCGCAGGGCGAAGAATATATATTGCCCGATGATAAAAATCTGGAACGGGAACAGTTGAGCAACAGCAGCAGCCATTTGCCATCAGCCTCGGCATCCACATCGACGTCTTCTTCATTTGCTGCTGCTGCAACAGAAAGCAGTTTAGTGGGTGGTTTAGGTCTCAACATACGCACAGATGAGAAAATGCCAGCCAAGGGAGAAATATCAGAGCAGGAGAGCAATTGTGACATTGAGAACTCCTGGAGTCAATCGGTAGGTATGTACGGCGACATATCACAGCGTTACTTTAGAAATCAGTTCTCAGATGGATACAATCAACAGCTGGCCGATTGGCGTCAGGATTACTATCCGGCGCAAGATCTCAGTGGCCAGCAACCGCAGCAGGAGCAGCGTGAGCACAAACGCACTTTTGATTTTAATGCCGTCGCTTCGGACTATGCACAACCGGGTGATCTGGACGCCTCCTCGAGCTCGGCGAGAAGCAACAATCATTTGTTGGATGCTCAACCCACCACCTCATCATCGTCATCGGCATTGCTGGCTGGTCCACCAATTGCCTCGACTTCACGCGCCGCAGCCGAAGCAGAAGCAGCTGTTGCAGCTGCGTTGGCACAACGCAAGCCACCGCGTCGCAAAATTTACAAGTGCCCGCATTGTGTGGCCATCTTTGAGAAGCTGAAAGAGCGCAATGCTCACATGATTGGCGAGCACAATTATGTGCGGCAGAATCGGCGTTTGATCTGTACACAGCCACTGGTTAGTGGCACAATAATGTCGCAGCCACAGGATGCGCAACAGCAGCAGCCGCAGCAGTTATCTCTGCAACCGGAGTTAAGCGATGTTGCTGCTCTGCAAGAGGATTCCAAGGATGGCATAGTGAAGATCAAGCAGGAACATTGTCAAGATAAACAAGACACATCAGGGCAGATGCTTGATCAAATGGAGCTACCCGACGTGAAGGATGCCGATTTACTTGATGTGAACGGCTCAAATGGACGCGATGCCGATATGAAACCACCGACAAGCACCACTGAAATAGATCAGAAGCCATCAATGGCACCATTGGCAATTACCACACCTGCTGCCAAGCTGGCGGCACTTTATCGCATGCTTATTTCCTACAATGAATCGAAACTGGGGCAGGAACGTAACAATCTCAGCGAATTGGAGCAAAAGGCCATGGAGAAATCCATATTTCTTTGCTATGTTTGTCGTACGGATTTTCCTTCGGTAAAACTCTACGATGCCCATTTAACGGAACATCCCGCTGAGTGTTTTACGTGTGGCAAGAAATTCTATCGCTGGAAGAACTTCTCATTGCATCTGAAGCGTCATCTCGGCTGGAAGGAATTTGGCTGCTATGTCTGTGACAAGAAGTTTGTGGTGCGCAGCGCTCTGGTCGAGCACATGCGTATGCATACGGGGCAGAGTCCACTCAAGTGCAAGATATGTGGCAAAAAATTCAAGCGTTACTCCAATTTGACGCAACATCGCAAGCGACACACCAAAATGATGGTGCGCAAAAAGGAATATGTTTGCCACTGCGGCGAAGTGTTACCGTCGAAGGCACGTTTTCTGTGGCACAAGGAGACGCATGATCTGAAGCCCAAATGCTGTCCCTATTGCTGCGATCGTTTCGTGCACGCCAATTCGCTACGTCGCCACATACGACTGGCGCATTCGGATAAGTTCGACTATGCCGAGCCAATGGAGTGTCCCATGTGCAAGCAGATATTCGCCAAGACATCGATAAAGGCGCACATGGCAACGCATTCGACAGATCCGCAATACGATTGCGCCATCTGCAACAAAAGTTTCTCCACCAAATGGAATCTCAAAATACATTCGTGGGTGCATGCGAATCGCACAGCCAAACCCTTCAAGTGCGAGTACTGCCCCAAGGCATTTGTGCGTGAACTGGACTTTAAGAACCATATGAATGCACACAAGCAGATCAAACCGTACACCTGTGAGTATTGTGGCTGCAAGTTCATACGCAAATACAACTATATGCGGCATCGGCGGGAGCATCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAATCCTTCCATCGACATTACTATCTGATCGAACATCGGCGCATTCACACCGGGGAACGGCCCTTCCATTGTACGATTTGTGGCAAGAGCTCCACCACGAAAACCAATCACAACAAGCATCTGAAGATTCATCATTCGCGCGATCCCTTCACAGTGGAGGTCTAA
Protein Sequence
MVESMQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNNVAGSSLATAVLSTAAGCGTTDGSGSGGSTSSTSSSAMSFAPPPTEALAATTSNAPTTSSSVATVYPPTLTSDYRYEQQPPPPATSLHGFARGSNTSLVIPHPPQQQQQHFLTNQQQPGHFAAQQQQQQSPMKYAYAAHATLPPPPPPPLQLFAQQSTTTLSHQKPPPAYGAAITAQHNVNLAPPSGKHSKIHTDIFLNPPPPPPPQSTLPTSSGRNISSRQSTNSPFGALLNAAAQAAYVPPAAGAPSVLRFAESPVAHYLERDNGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDDDDEDKQETEEKVHNWTHSEDEDQSKVSHGHVDDGDDEREDSRSRVGVKQTTKRTSRKTKSGGRISKRTSKHHQHQPVEDEDDFMSVGSSCADSDHQSDQLHQHHQQPQNASSAVLASSSSSSSAQHLSTAPSTSAAAAAAANSSGASSATGSSSGATKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIAKVQGPTGELVQIKSERTEVASGTGSILEKHLTTSYAATQHQQQQQLQQQLSRKHSSVNDDDARVLLEFANSNSKQQQTQSGTTFVVNAASFASAGSVFASSSNAVGSPSAKKANTSQGEEYILPDDKNLEREQLSNSSSHLPSASASTSTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSVGMYGDISQRYFRNQFSDGYNQQLADWRQDYYPAQDLSGQQPQQEQREHKRTFDFNAVASDYAQPGDLDASSSSARSNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQPLVSGTIMSQPQDAQQQQPQQLSLQPELSDVAALQEDSKDGIVKIKQEHCQDKQDTSGQMLDQMELPDVKDADLLDVNGSNGRDADMKPPTSTTEIDQKPSMAPLAITTPAAKLAALYRMLISYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQSPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01558467;
90% Identity
-
80% Identity
-