Basic Information

Gene Symbol
-
Assembly
GCA_035046045.1
Location
JAWNOI010000086.1:686113-698730[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.00054 0.034 14.4 2.3 1 23 855 877 855 877 0.98
2 7 0.00023 0.015 15.6 1.3 1 23 909 931 909 931 0.97
3 7 0.0047 0.3 11.5 0.0 3 23 968 989 967 989 0.96
4 7 0.00027 0.017 15.3 3.5 1 23 995 1017 995 1017 0.97
5 7 0.039 2.5 8.6 0.2 1 23 1024 1047 1024 1047 0.95
6 7 0.00035 0.022 15.0 2.2 2 20 1054 1072 1053 1075 0.91
7 7 0.5 31 5.1 9.2 1 23 1081 1104 1081 1104 0.92

Sequence Information

Coding Sequence
atggaTAACAAAACTACACAGTTGGATTTTAAATTACTGGTGGATCAGTCAGTGAATCTACTGGATAGCCTGAGTGCGGCGTCGCGGTGCGATGCAATCAAGTTTCTGCTGCAAACGCTTAAGTGCAAATATCCGGATGCCTGCGACCGAGTCGTCAGGAGTCTGTTCAGTCACAAACccaatgataatgataatcaGGATGAGCTAGCGAAGTgcaagcaactgcagctgctgcttgcgacgacgacgacgccaacgGCGACGCCCAAGAAAGAGAAGACGGATCCCGATCTGGATGGATGCGGCCTGGAGACGTTGCCCGTTTCGGTTGCGAAAATCAAGCGCGAGAGCGCAGACAGTGTCGTCGATGGGGGACGgggaccagcagcagctgcgatcGATTTAAATCAAAACGTTGAAAAGATTCTCTGCAAGGAGGAGTTTATGTGCCTCGACGAGGAGGATGACTTCCTCGATGATGACGCCGaagccgatgccgatgccgacaCTGAGAACTCGTCTTCCATGAGCAAACGCCTGCACTTTCATCGCTccacgaacagcagcagcagcagcagcatagccAAAGCCCAGCGCATCAGTGGTGGGAGTAGTAGCAACAATGTGGACGCGACTGCCAGTGCAGTCGCGTCTGCGCAGCTCAACAGCGATCCCCTCGATCTGATACCGACGGCAGCGAATGCAGCCAGCAGCGGCTTGATCAAGCGCAAATATGCAGCGACATTCGATGAGCTGCTGGACATGGATGCCGACGAGAATGATGTGCAGGCTGAAGCTTACGAcgacagcaatagcaacagcaacagcaacggctgCGAGGAGCTGCTCCTGCATCGCAAACAGAAGCTAATCCGTGGCGCCGGCCTCTCTGTGAAACGAAGGCGCGTCAACAACTTCATTGGCAGCCTGAACGCAGTGGCGGTGGCGCCCGTTGCCCGCTCCCGTCTGGGCGAGGGCTATGTGTTCCACGAGGACACACAGTACACGCTGCGCTATCATCACAGCAGCGGCGAGTTCAGCGAGCGGGCGTACAAGGCGCAgttccggctgctgctgcgactggcaCTGAGCCAGCACCACAAGCCCTTCCTCAAGCAGTTCTACGAGAATTTCGTGGTCACCGGGCGGCTGCTGGGCACCACGCCGTCAGCACGCGTGCTGAAGGAGCTGCGCGAGCAGCGACTGGAAGAATGGCGGCGGCAACGCGAGCGCAGACAACTGGCCAAGGCGGCAGCtgaggcagaagcagaggcagaggctgccgcggctgctgctgctgcacggcaactggagcaacagttgctgaagcagaagcaacagcagcagcaacaggagcaacaacaacatcagcagcagcgggagcaacagcagcgggagcagcaacaactgcagctggagcagagccAACAAATGGACCAACAACTGGATGCGTCCCTGCAGCTGGTGGATGGCcaagagcagcgccagctcagATCCATCTCGTTTGGCGACTCGGAGCTCGAGTCGGAGACGGAATCGCAGCtctcgtcggcggcggcgcaggGCATCATGAAGTTCGAGGAGTTCATTGACGAAGGTTTGGGCGCAGGACGTCTCATCGATGGGCTTGAGATGGAACCGGAAATAGACGAGATGCTTGCCGGCGCCGGCAGTGGGCTGGGCAGTGTGACGGGCACCGGCAGcgggaacagcaacagcaacagcagcgccgtcCATGACAATGGCCATGACATCGCCTCGCTGCTCCTGGACAGCGGCCATCAACTcagcagcagcagcacgagtgTCGCTGCAAATCTTGTGATCAACGGCCTTACTTCAAGcaatatcaacaacaacaacaacaacaataacaacaacaacaacgactgcaACAAGAGCCAGCAGCTGAGCGAGTCGGAGCAGCATGCGAGCAAGCAGCccgtgcagctgcagtcgcactcgcagtcgcagtcacagtcgccgAATTTGCCATTGCCCATGAGATCGGCCTATGGCCATGAGGTTGCCTCGCAGCTGATGTCCGGCTCGGAGATTCAGCTGCAGAACGATAGCCCCAGCTCGAATCAGAgtcaacaccagcagcagcaccagcatcagcaccataatccgaatccgaatcagAATCATTATAACTCAAGCAATAATCCGCTCTCGATGATGGGCGGCATGATGCagatgcagcaacagcagcagcagcagagtcccTTTCCACAGCATGCGCATGCGCATGCGCAGCTGATGAACAATCGCCAGCCTCAGCTGCATCCACATGCGCCGCTGCATTCGCATGCGCCGGGACAGCCGCCGCATCTGGCAGCTGCATCGCTTGTGTCGCAGTTGAACTCTTCGCTGGAGCTGGACGACAACGAGCTGTCGggcgacgaggacgacgacgagttGGACAACGAGCTGGACGAACTGGACgctgccaagcagcagctcatcgatggcggcagcagcagcagcacttcgcTGCAGGCACCGCCCTCGCAGCTCGGCGGCAGCCAGACGCCTGGCAGCAAGAAGGACAAGCCCAGCTACAATTGCCTGCTGTGCCCGAAGTCGTACAGGAAGCGCAAGTCGCTGCTGGATCACTACAAGACGCATCCGGGCTACTGTCACGACTGCGGCCAGCCCAATGGCAACACGCTGGAGGAGATAATCCAGCACAATCGCACGGTGCACGCGAAGGAGTATCCATTTGTGTGCGACACCTGCGGCGAGTCCTACTCGCGCCGGCAGCAGTTCCACGCGCACGTCGAGTCGCACAAGAAGGAATCGAAATTGTCCAATTGCGGCGAGTGCGGCCTTAAGATGTCgcagaagaagctgcagcagcacttcgAGGAGACGGGCCACAAGGCCGATGGCGCCATCTGCGAGGTCTGCGGCGCCGACTTTGCCTCGAAGAACGCGCTCTACCAGCACATCATCAAGGTGCACAAGCGCGACAACTTCTTCGAGTGCCACATTTGCCATAATCGCTTTACGCTCAAGGCCAATCTGGAGCGGCACGTGCAGCTGCACACGGAGGTGAAGCGCACCTATGTGTGCGATCTGTGCGGCTCCTCCTACTTTACATATCCGGCGCTCAAGGAGCACTACAGCAACGCCCACGTCGATGTGTCCGAGTGCAAGTGCACGCTGTGCGGCAAGCGCTTCGGCTCGGCCAAGTCCCTGCAGCGTCATCTGCCATCGCACTCGGAGGAGCGACCGCACTGCTGCAATCACTGCGATCAGACCTTCAAGTGGAAGACGCATCTGGTGCGCCACAAACAGGCGATGCACGGCAACCAACCGCCGCCTCCCAAGAAGGCCAAAGGTCAGCGTTTCCCCAAGGCCAATGAGGAGGatctgctgcccctgcccgacATGCCCGGCCCGCCGCCGGTGAAGGCAACCAAAAAGTCAGCCGCCAGCAAGGCAAAGTCTCAGGCCGCggcagttgctgccgccgcagcgcaacagcagcagcagcaacaacaacaacagggtaTCGTGGGCAAGGGTGTTGGCatgggtgccacgcccacaccgccaccgccgctaTCGACGACGCCGGGCTGCTCGCAGCAGGATCCCTTCAATGCCGCCATggtgagcagcaacagctcgcaGTCGTCGACGGCCTCAACGTCGCAGCACTCGGTCTCCACGAGCGAATCTCAGCAGAATTCCATGTACAATCAGAGCTTTAATGCggacaagctgcagcagcaacaacagcaacagcagcagcagccgccgacgcagcagcagcagcagcagcagaatgcgttacatcatcagcaacagcagcagcaacatgctgcAGCCACGCCACCgccaacgcagcagcagcagcagcaacaggtgccacaaccgcagcagcagcagcaaccgcagccGCATCATCGCCATACGCATACGCCGAACAACAGTACGCCGGAGCTGCATCTGCAGCGGATGAACAGCTTTGGCGGGCAGCCCGAGAGCCAGTTCCACTTCGAGCCGACTAGCAATGCTGCTGGTGCCTATCAGCAACATCAGCTGCTCAGccagtaccagcagcagcagcagcagcaacaacaacagcagcagcagcaggcacaacagcaacaacaaccacagcaggCGCAACTCATGCGCAGTCACACGCCGCAGAGTCCACATCCGCATCCACATCCCCATCCACATGCACACcaggctcagcagcagcagcagcagatgcaacagcagcagcatttcaaCTCGCCGCACCACATGCCGCCAATGCACCACCAGCATCAGTTGCTCATGCAGCAGCATCGCCACACGCActcgccgcagctgcagcattcgCGTCTGCACTCGCCGCAACCGCAACCGTCGCcctcagcggcagcagcagcagcgacaccacagcagcagcagcagcagtttatgcagcagcaacagcaggcagccgaTGCGTGGGGCAACATGAGTTTTGGTGGTGCAGCAAGTAACCAGCAGGTCGAGCTGAAGGACAAGTTCTACATAGTCGACTCAGCCGAGTTTCTGGGGCTTCCGATGGGTGTTGGTGGCGCTGCGCCgccgacgcagcagcaacagcagcctgCTATAGTCAACAaggcgcaacaacagcagcagcagccacagcaacaacaacaacagccacagcagcagcctcaggATGCAGCGCTGGGTGGAGATCTGCTGAGCTTCCAGCACATgtggccgcagcagcagcagcaacaacaacagcagcagcagcaacaacaacagcaggcgccCACAGCGCAGGCGCAGTCGAATCAGGTGGGCCCGGGAGATGctcacaactacaacaacattgGCAGCATACTGACGAATCTCATAGATACGAATCCTGCACCCTTGGAGTACAACTTCGATCTGATGCAGCAGCaagcgccacagcagcaacagcaagcggtgcagcagcaacagcaagcggcgcagcagcagcagcagcagcaggtcgtGCAGCAACATCACAACGCCGGCGGTGCTTATGGCGGCGGTCTGATGCGTCATGCGGGCGCCGGCAACGTCTACTCCTACGAGGCACATCACAatcacgagcagcagctcgtcaaCGATCAGCAGAAGCACAACAGCTTCCAGCCCTACGGCCATGGGCATCCGCATGCgcacgcgctgcagcagccgctgcactcgctggcagctgccacacacctgttgccgccgccgccgccgcatgGCAATGTCTACGAGCGCACGGTGGCACCGCCagtgggtgtgggcgtgggcgtgggcgtcaATGTAGGCTATCCCATGATGGGCGACGATACGAAGTCGGTGCTGCCGCCGATCAACGACTACATGCAtcatatgcagcagcagcagcccgatcTAATCTATTATCCAGTGAAGAACGATTGA
Protein Sequence
MDNKTTQLDFKLLVDQSVNLLDSLSAASRCDAIKFLLQTLKCKYPDACDRVVRSLFSHKPNDNDNQDELAKCKQLQLLLATTTTPTATPKKEKTDPDLDGCGLETLPVSVAKIKRESADSVVDGGRGPAAAAIDLNQNVEKILCKEEFMCLDEEDDFLDDDAEADADADTENSSSMSKRLHFHRSTNSSSSSSIAKAQRISGGSSSNNVDATASAVASAQLNSDPLDLIPTAANAASSGLIKRKYAATFDELLDMDADENDVQAEAYDDSNSNSNSNGCEELLLHRKQKLIRGAGLSVKRRRVNNFIGSLNAVAVAPVARSRLGEGYVFHEDTQYTLRYHHSSGEFSERAYKAQFRLLLRLALSQHHKPFLKQFYENFVVTGRLLGTTPSARVLKELREQRLEEWRRQRERRQLAKAAAEAEAEAEAAAAAAAARQLEQQLLKQKQQQQQQEQQQHQQQREQQQREQQQLQLEQSQQMDQQLDASLQLVDGQEQRQLRSISFGDSELESETESQLSSAAAQGIMKFEEFIDEGLGAGRLIDGLEMEPEIDEMLAGAGSGLGSVTGTGSGNSNSNSSAVHDNGHDIASLLLDSGHQLSSSSTSVAANLVINGLTSSNINNNNNNNNNNNNDCNKSQQLSESEQHASKQPVQLQSHSQSQSQSPNLPLPMRSAYGHEVASQLMSGSEIQLQNDSPSSNQSQHQQQHQHQHHNPNPNQNHYNSSNNPLSMMGGMMQMQQQQQQQSPFPQHAHAHAQLMNNRQPQLHPHAPLHSHAPGQPPHLAAASLVSQLNSSLELDDNELSGDEDDDELDNELDELDAAKQQLIDGGSSSSTSLQAPPSQLGGSQTPGSKKDKPSYNCLLCPKSYRKRKSLLDHYKTHPGYCHDCGQPNGNTLEEIIQHNRTVHAKEYPFVCDTCGESYSRRQQFHAHVESHKKESKLSNCGECGLKMSQKKLQQHFEETGHKADGAICEVCGADFASKNALYQHIIKVHKRDNFFECHICHNRFTLKANLERHVQLHTEVKRTYVCDLCGSSYFTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNHCDQTFKWKTHLVRHKQAMHGNQPPPPKKAKGQRFPKANEEDLLPLPDMPGPPPVKATKKSAASKAKSQAAAVAAAAAQQQQQQQQQQGIVGKGVGMGATPTPPPPLSTTPGCSQQDPFNAAMVSSNSSQSSTASTSQHSVSTSESQQNSMYNQSFNADKLQQQQQQQQQQPPTQQQQQQQNALHHQQQQQQHAAATPPPTQQQQQQQVPQPQQQQQPQPHHRHTHTPNNSTPELHLQRMNSFGGQPESQFHFEPTSNAAGAYQQHQLLSQYQQQQQQQQQQQQQQAQQQQQPQQAQLMRSHTPQSPHPHPHPHPHAHQAQQQQQQMQQQQHFNSPHHMPPMHHQHQLLMQQHRHTHSPQLQHSRLHSPQPQPSPSAAAAAATPQQQQQQFMQQQQQAADAWGNMSFGGAASNQQVELKDKFYIVDSAEFLGLPMGVGGAAPPTQQQQQPAIVNKAQQQQQQPQQQQQQPQQQPQDAALGGDLLSFQHMWPQQQQQQQQQQQQQQQQAPTAQAQSNQVGPGDAHNYNNIGSILTNLIDTNPAPLEYNFDLMQQQAPQQQQQAVQQQQQAAQQQQQQQVVQQHHNAGGAYGGGLMRHAGAGNVYSYEAHHNHEQQLVNDQQKHNSFQPYGHGHPHAHALQQPLHSLAAATHLLPPPPPHGNVYERTVAPPVGVGVGVGVNVGYPMMGDDTKSVLPPINDYMHHMQQQQPDLIYYPVKND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-