Basic Information

Insect: Zaprionus bogoriensis
Gene Symbol: zfh1
Assembly: GCA_035046045.1
Location: JAWNOI010000030.1:504607-529779[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.024 1.5 9.2 1.5 2 23 79 101 78 101 0.95

2 9 0.001 0.064 13.6 0.1 1 23 299 321 299 321 0.97

3 9 1.9e-05 0.0012 19.0 0.6 2 23 335 356 334 356 0.97

4 9 5.4e-05 0.0034 17.6 4.9 1 23 365 387 365 387 0.99

5 9 0.0014 0.091 13.1 1.7 3 20 395 412 393 414 0.93

6 9 0.028 1.8 9.0 0.4 2 21 647 666 646 667 0.92

7 9 4.8e-05 0.003 17.7 0.5 1 23 1020 1042 1020 1042 0.94

8 9 5.1e-05 0.0032 17.6 7.4 1 23 1048 1070 1048 1070 0.98

9 9 0.0026 0.16 12.3 4.3 1 21 1076 1096 1076 1097 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.024	1.5	9.2	1.5	2	23	79	101	78	101	0.95
2	9	0.001	0.064	13.6	0.1	1	23	299	321	299	321	0.97
3	9	1.9e-05	0.0012	19.0	0.6	2	23	335	356	334	356	0.97
4	9	5.4e-05	0.0034	17.6	4.9	1	23	365	387	365	387	0.99
5	9	0.0014	0.091	13.1	1.7	3	20	395	412	393	414	0.93
6	9	0.028	1.8	9.0	0.4	2	21	647	666	646	667	0.92
7	9	4.8e-05	0.003	17.7	0.5	1	23	1020	1042	1020	1042	0.94
8	9	5.1e-05	0.0032	17.6	7.4	1	23	1048	1070	1048	1070	0.98
9	9	0.0026	0.16	12.3	4.3	1	21	1076	1096	1076	1097	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCTATCGTCGACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCGTGCAGTTTCCCTCTTTGGCCTCCAGCCTGCATCATCATCAAGCACACAACAAGCCCAGCAATGTGGCTGCCACaagcgaggaggaggagcacgCCCCACACGCGGCCAGTGCGACGGCGAGCGCTGGCGAGGATTACCTGGTCAAGTGCACGCAGTGCCACCAGCGCTTCAATGAGTTCCAGtccctcagCGAGCACATTGCCAGCGAGCATCCGCACGACAAGCTCAACTACGAGCCAAATCGCGCGGCTGGCGCAGTGCAGCCCGAGAGCGAGGCTGAGGAGGACGAGCAGAGCAatctgagcagcagcagtcgacgcTACGCCAAGTCgccggccagcagcaacaacaacaacaacaacaacagcgagacaACCAAGAatcagaacaacaacagcagcagcagtcgcagccaaCACTCGCCGCTCTGCTCGCCCGTTgcgcatgccacgcccagcgatCTGTTCGCCCACCTGCCGCATCCGCCCCCGCAGCTGCCCGCCGACCTGCACCGCCAGCTCATGGCGGCCGCCGCCTCGCTGGCCATGCAGTCCGCACGCTCCGCCAGCTCGCCcaaccagctgcagcaggcgcagcagcgacagcagcagcagcaggcacaacagcagcagcaacagttgctgctgccgccaccgggacagcaacaacagcatcagcagcagcagccgggcagcaacagcagcagcattggcagcaACTCCGCCTACGATCTGGACCTGAGCACGCCGCGCTCCACCTCCAGTCCAGGCTCGACGACGGGCGACGGCCTCAGCCTGAATGCCTTCCCCTGCATGCAGTGCACCGCGGCCTTCCCCACAcgcgagcagctcgagcagcaccagctgctgcactcgccCAGCGGACAGCCGGCCGCACAGAACGTGACGCAGTCGTGCAAAATTTGCAACAAGGCGTTCGCAAACGTGTACCGCCTGCAGCGGCACATGATCAGCCACGACGAGTCCGCGCTGCTGCGCAAGTTCAAGTGCGGCCTGTGCGAGAAGGCGTTCAAGTTCAAGCACCACCTGAAGGAGCATGTGCGCATCCATTCCGGCGAGAAGCCCTTCGGCTGCGACAAGTGCGGCAAGCGCTTCTCGCACTCGGGCAGCTTCTCTTCCCACACGACCTCGAAGAAGTGCACCAACATGAACCTCAAAgtcagcaacggcaacaacagcaacagcaacaacaacaacaacagcagcaacagcaacccgagcagcaacagcaatcgGCAACTGCTGAAGAGCCTGGACAAGAACGCGAGCGCTGGACGCTCCTCCGCCGACcacctgcagccgctgctggcggGCAAGCGCGTGCCTAATCCCATGAACTACTTTGCCGGCGAGGCACAGGTGGCCGCTGGCAATGCACCCGCTGCCTTCTACCACAACTACGCGGCGCTGATGAGCTTTCCGAATGCCTTCATCACCGCCGCGCTGGATCCGCGCATGCATCCGTACAGCATACAGCGCCTGCTCGAGCTCACAGCTGCGGGCCAGCAGCATCGCGAgGAACAGGAGGAGGAGCCGCTCTACGAGCGCAGCCAGGACGACGATGAGACGCCCGACGAGCCTAAGCTTGTGATGGATCTGGAGGAGTCCGAGCAGAAATCggcgacgccagcgccagagcagcagcctgcagccgAGGCAGTTGCCGAGGCCGACAGCTTCAAGCAGGAGCCTGTGCGGGAGCCAACGCCAGTGCTGCACAGTGCACCCGCAACACCCAAGTCCATCAAGTTGGAGCagcaagaggaggaggagcaactgGCGACGCCTGTGGAGGAGGAAACGCGTGCGCCGACACCGCAGGAgctgcgctgcagtcgctgcgccaAGCAGTTCAATCATCCCACAGAGCTCGTGCAGCACGAGAAGGTGCTCTGCGGGTTCATCAAGGAGGAACTCGAGCAGcacttccagcagcagcagcagcaacaacagcagcagcagcagcaggcaagctTTGTGCTGCCCGCCGCTAGCGACGCCGACgatgacgaggaggaggaggaagagccACGCCCAGACTTcaatgccggcagcagcgacagcggcgagCGCAAGGTGCGCGTGCGCACCGCCATcaacgaggagcagcagcagcagctgaagcagcactACGCCCACAACGCGCGTCCCAGTCGCGACGAGTTCCGCATGATCGCCGCGCGCCTGCAGCTCGATGCACGCGTCGTCCAGGTTTGGTTCCAGAACAATCGCTCGCGCGAGCGTAAGCTCCAGAGCTACACGAGCAGCACGGAGCATGCCGCTGGCActgccgtcgccgctgccgtctccagcgctgcgctgccggcgcgtGCTGGTGCCGAGGATCAGCCGCTGGATTTGTCCGTGAAGCGGGATGCCTCGCCGCTGTACGGCCTGGCGCCGCAGCAGACGCCAGTCGCCGACTTCCGCGAGGAGGCGATGGCCATCAATTTGAGTCGCAAGCTCTCCAGCTCGGCCTCCATGTCGCCGGCTTCGCTGTCGCCCTGCTCGGGTGCCTCCTCGCTGCAGCAgaccgcagctgctgctgccgcggcagCTCTGTACTTTGACCCAAGCCTGCCGGCCGGCGTGCACGAGGTGGCACCACCCATGCCGCCACATGGTGCGGCAGCTGTCCCGCCACGCGGCCAGCCCTTTGTCGGCCTGCCGCCGTACATGATGCAGCGCCTGCCCATGGACGCGCTCTTCCAGATGCGACCCGGCGGCGACTATGCGCCCAATCCGCTGATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGCCTCAGTCCTGGCGGCTCCGAGAAGCGTTCGTGGCGCGACGATGATTCACGCATCTCGCATGAGGATGACTACGTGCTGGCCGGCAATGGGTTGCTGCCGCCGAAGCCTAAGCGCGTCAAGGCCGAGACGCACGGGCATGCGGGCGATCCGGATCTGCCCTTCGTCTGCGATCAGTGCGAGAAGGCGTTCGCCAAGCAGAGCTCGCTGGCGCGTCACAAGTACGAGCATTCCGGTCAACGACCCTACCAATGCATGGACTGCCCCAAGGCCTTCAAGCACAAGCACCACCTGACGGAGCACAAGCGCCTGCATTCCGGCGAGAAGCCCTTCCAGTGCTCCAAGTGCCTGAAGCGCTTCTCGCACTCGGGCAGCTACAGCCAGCACATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLALSSTRFGQEDNIIQQSMPSSTAFSVQFPSLASSLHHHQAHNKPSNVAATSEEEEHAPHAASATASAGEDYLVKCTQCHQRFNEFQSLSEHIASEHPHDKLNYEPNRAAGAVQPESEAEEDEQSNLSSSSRRYAKSPASSNNNNNNNSETTKNQNNNSSSSRSQHSPLCSPVAHATPSDLFAHLPHPPPQLPADLHRQLMAAAASLAMQSARSASSPNQLQQAQQRQQQQQAQQQQQQLLLPPPGQQQQHQQQQPGSNSSSIGSNSAYDLDLSTPRSTSSPGSTTGDGLSLNAFPCMQCTAAFPTREQLEQHQLLHSPSGQPAAQNVTQSCKICNKAFANVYRLQRHMISHDESALLRKFKCGLCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHTTSKKCTNMNLKVSNGNNSNSNNNNNSSNSNPSSNSNRQLLKSLDKNASAGRSSADHLQPLLAGKRVPNPMNYFAGEAQVAAGNAPAAFYHNYAALMSFPNAFITAALDPRMHPYSIQRLLELTAAGQQHREEQEEEPLYERSQDDDETPDEPKLVMDLEESEQKSATPAPEQQPAAEAVAEADSFKQEPVREPTPVLHSAPATPKSIKLEQQEEEEQLATPVEEETRAPTPQELRCSRCAKQFNHPTELVQHEKVLCGFIKEELEQHFQQQQQQQQQQQQQASFVLPAASDADDDEEEEEEPRPDFNAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRMIAARLQLDARVVQVWFQNNRSRERKLQSYTSSTEHAAGTAVAAAVSSAALPARAGAEDQPLDLSVKRDASPLYGLAPQQTPVADFREEAMAINLSRKLSSSASMSPASLSPCSGASSLQQTAAAAAAAALYFDPSLPAGVHEVAPPMPPHGAAAVPPRGQPFVGLPPYMMQRLPMDALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVLAGNGLLPPKPKRVKAETHGHAGDPDLPFVCDQCEKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01549473;
90% Identity: iTF_01549473;
80% Identity: iTF_01549473;